Upstream Bio (UPB) News Today $9.22 -0.40 (-4.16%) Closing price 05/28/2025 04:00 PM EasternExtended Trading$9.20 -0.02 (-0.22%) As of 05/28/2025 06:45 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Headlines Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOwnershipSEC FilingsTrendsBuy This Stock UPB Latest News All Sources Trusted Sources MarketBeat Benzinga Bloomberg GlobeNewswire GuruFocus MarketWatch Motley Fool NASDAQ PR Newswire Reuters Seeking Alpha TalkMarkets The Street TipRanks The Wall Street Journal Wall Street Zen Yahoo Finance Source Sentiment refers to the positivity or negativity of each headline according to our language processing algorithm. Sentiment All Sentiments Very Positive Positive Neutral Negative Very Negative Most Recent May 2025 April 2025 March 2025 February 2025 January 2025 December 2024 November 2024 October 2024 September 2024 August 2024 July 2024 June 2024 May 2024 April 2024 March 2024 February 2024 January 2024 December 2023 November 2023 October 2023 September 2023 August 2023 July 2023 June 2023 May 2023 April 2023 March 2023 February 2023 January 2023 December 2022 November 2022 October 2022 September 2022 August 2022 July 2022 June 2022 Time Period Jane Street Group LLC Takes Position in Upstream Bio, Inc. (NASDAQ:UPB)Jane Street Group LLC bought a new stake in Upstream Bio, Inc. (NASDAQ:UPB - Free Report) in the 4th quarter, according to its most recent 13F filing with the Securities & Exchange Commission. The institutional investor bought 45,549 shares of the company's stock, valued at approximately $749,May 27 at 3:03 AM | marketbeat.comNorthern Trust Corp Makes New Investment in Upstream Bio, Inc. (NASDAQ:UPB)Northern Trust Corp purchased a new stake in Upstream Bio, Inc. (NASDAQ:UPB - Free Report) in the fourth quarter, according to its most recent filing with the SEC. The fund purchased 143,721 shares of the company's stock, valued at approximately $2,363,000. Northern Trust Corp owned about 0.27% ofMay 27 at 3:02 AM | marketbeat.comWoodline Partners LP Buys New Stake in Upstream Bio, Inc. (NASDAQ:UPB)Woodline Partners LP purchased a new position in shares of Upstream Bio, Inc. (NASDAQ:UPB - Free Report) in the 4th quarter, according to the company in its most recent Form 13F filing with the Securities and Exchange Commission (SEC). The firm purchased 526,511 shares of the company's stock, valueMay 25, 2025 | marketbeat.comVR Adviser LLC Takes $37.74 Million Position in Upstream Bio, Inc. (NASDAQ:UPB)VR Adviser LLC acquired a new stake in shares of Upstream Bio, Inc. (NASDAQ:UPB - Free Report) during the 4th quarter, according to the company in its most recent 13F filing with the Securities and Exchange Commission (SEC). The institutional investor acquired 2,295,319 shares of the company's stoMay 22, 2025 | marketbeat.comUpstream Bio names new chief technology officerMay 21, 2025 | investing.comUpstream Bio Appoints Stacy Price As CTOMay 21, 2025 | nasdaq.comUpstream Bio, Inc. Appoints Stacy Price as Chief Technology Officer to Lead Expansion of Technical OperationsMay 21, 2025 | nasdaq.comUpstream Bio Appoints Stacy Price as Chief Technology OfficerMay 20, 2025 | globenewswire.comOrbimed Advisors LLC Takes Position in Upstream Bio, Inc. (NASDAQ:UPB)Orbimed Advisors LLC acquired a new stake in shares of Upstream Bio, Inc. (NASDAQ:UPB - Free Report) during the fourth quarter, according to its most recent filing with the Securities & Exchange Commission. The firm acquired 5,693,589 shares of the company's stock, valued at approximately $93,6May 15, 2025 | marketbeat.comBalyasny Asset Management L.P. Invests $4.95 Million in Upstream Bio, Inc. (NASDAQ:UPB)Balyasny Asset Management L.P. acquired a new stake in shares of Upstream Bio, Inc. (NASDAQ:UPB - Free Report) in the fourth quarter, according to the company in its most recent 13F filing with the SEC. The fund acquired 301,152 shares of the company's stock, valued at approximately $4,951,000. BalMay 13, 2025 | marketbeat.comEnavate Sciences GP LLC Acquires Shares of 2,459,703 Upstream Bio, Inc. (NASDAQ:UPB)Enavate Sciences GP LLC bought a new position in shares of Upstream Bio, Inc. (NASDAQ:UPB - Free Report) during the fourth quarter, according to the company in its most recent filing with the Securities and Exchange Commission (SEC). The fund bought 2,459,703 shares of the company's stock, valued aMay 11, 2025 | marketbeat.comQ2 EPS Estimates for Upstream Bio Decreased by William BlairUpstream Bio, Inc. (NASDAQ:UPB - Free Report) - Research analysts at William Blair cut their Q2 2025 earnings per share (EPS) estimates for shares of Upstream Bio in a research report issued to clients and investors on Tuesday, May 6th. William Blair analyst M. Phipps now forecasts that the compaMay 10, 2025 | marketbeat.comDeep Track Capital LP Takes Position in Upstream Bio, Inc. (NASDAQ:UPB)Deep Track Capital LP bought a new position in Upstream Bio, Inc. (NASDAQ:UPB - Free Report) during the fourth quarter, according to the company in its most recent filing with the SEC. The firm bought 1,000,000 shares of the company's stock, valued at approximately $16,440,000. Deep Track Capital LMay 9, 2025 | marketbeat.comAlyeska Investment Group L.P. Invests $1.40 Million in Upstream Bio, Inc. (NASDAQ:UPB)Alyeska Investment Group L.P. purchased a new stake in shares of Upstream Bio, Inc. (NASDAQ:UPB - Free Report) during the 4th quarter, according to the company in its most recent 13F filing with the SEC. The institutional investor purchased 85,000 shares of the company's stock, valued at approximaMay 9, 2025 | marketbeat.comUpstream Bio Advances Verekitug in Clinical TrialsMay 7, 2025 | tipranks.comUpstream Bio Reports First Quarter 2025 Financial Results and Accelerates Guidance on All Clinical ProgramsMay 6, 2025 | globenewswire.comSamsara BioCapital LLC Acquires Shares of 2,217,146 Upstream Bio, Inc. (NASDAQ:UPB)Samsara BioCapital LLC bought a new position in Upstream Bio, Inc. (NASDAQ:UPB - Free Report) during the 4th quarter, according to its most recent disclosure with the Securities & Exchange Commission. The fund bought 2,217,146 shares of the company's stock, valued at approximately $36,450,000.May 2, 2025 | marketbeat.comSoros Fund Management LLC Makes New Investment in Upstream Bio, Inc. (NASDAQ:UPB)Soros Fund Management LLC bought a new stake in Upstream Bio, Inc. (NASDAQ:UPB - Free Report) during the fourth quarter, according to the company in its most recent 13F filing with the Securities & Exchange Commission. The fund bought 46,350 shares of the company's stock, valued at approximatelMay 2, 2025 | marketbeat.comTCG Crossover Management LLC Takes $44.86 Million Position in Upstream Bio, Inc. (NASDAQ:UPB)TCG Crossover Management LLC bought a new position in shares of Upstream Bio, Inc. (NASDAQ:UPB - Free Report) during the fourth quarter, according to its most recent Form 13F filing with the Securities and Exchange Commission (SEC). The fund bought 2,801,763 shares of the company's stock, valued atMay 1, 2025 | marketbeat.comNantahala Capital Management LLC Acquires Shares of 600,000 Upstream Bio, Inc. (NASDAQ:UPB)Nantahala Capital Management LLC purchased a new stake in shares of Upstream Bio, Inc. (NASDAQ:UPB - Free Report) during the 4th quarter, according to its most recent Form 13F filing with the Securities and Exchange Commission. The institutional investor purchased 600,000 shares of the company's sApril 30, 2025 | marketbeat.comJPMorgan Chase & Co. Acquires Shares of 47,792 Upstream Bio, Inc. (NASDAQ:UPB)JPMorgan Chase & Co. purchased a new stake in shares of Upstream Bio, Inc. (NASDAQ:UPB - Free Report) during the fourth quarter, according to its most recent Form 13F filing with the Securities & Exchange Commission. The firm purchased 47,792 shares of the company's stock, valued at approximateApril 30, 2025 | marketbeat.comLynx1 Capital Management LP Makes New Investment in Upstream Bio, Inc. (NASDAQ:UPB)Lynx1 Capital Management LP purchased a new stake in shares of Upstream Bio, Inc. (NASDAQ:UPB - Free Report) during the fourth quarter, according to the company in its most recent disclosure with the SEC. The firm purchased 240,042 shares of the company's stock, valued at approximately $3,946,000.April 29, 2025 | marketbeat.comDecheng Capital LLC Buys Shares of 3,285,293 Upstream Bio, Inc. (NASDAQ:UPB)Decheng Capital LLC acquired a new position in shares of Upstream Bio, Inc. (NASDAQ:UPB - Free Report) in the fourth quarter, according to its most recent 13F filing with the SEC. The institutional investor acquired 3,285,293 shares of the company's stock, valued at approximately $54,010,000. UpstApril 28, 2025 | marketbeat.comGeode Capital Management LLC Purchases New Position in Upstream Bio, Inc. (NASDAQ:UPB)Geode Capital Management LLC purchased a new position in Upstream Bio, Inc. (NASDAQ:UPB - Free Report) in the fourth quarter, according to its most recent disclosure with the Securities and Exchange Commission (SEC). The firm purchased 363,269 shares of the company's stock, valued at approximatelyApril 28, 2025 | marketbeat.comMarshall Wace LLP Makes New $4.78 Million Investment in Upstream Bio, Inc. (NASDAQ:UPB)Marshall Wace LLP purchased a new stake in shares of Upstream Bio, Inc. (NASDAQ:UPB - Free Report) in the 4th quarter, according to the company in its most recent disclosure with the Securities & Exchange Commission. The firm purchased 290,734 shares of the company's stock, valued at approximatApril 27, 2025 | marketbeat.comUpstream Bio (NASDAQ:UPB) Trading 7.2% Higher - Here's What HappenedUpstream Bio (NASDAQ:UPB) Trading 7.2% Higher - Should You Buy?April 23, 2025 | marketbeat.comBain Capital Life Sciences Investors LLC Acquires New Holdings in Upstream Bio, Inc. (NASDAQ:UPB)Bain Capital Life Sciences Investors LLC purchased a new stake in Upstream Bio, Inc. (NASDAQ:UPB - Free Report) during the 4th quarter, according to the company in its most recent disclosure with the Securities & Exchange Commission. The institutional investor purchased 2,295,322 shares of theApril 23, 2025 | marketbeat.comUpstream Bio: Verekitug, A Longer-Acting Dupixent? - Key Data Is ImminentApril 17, 2025 | seekingalpha.comFmr LLC Purchases New Position in Upstream Bio, Inc. (NASDAQ:UPB)Fmr LLC acquired a new position in shares of Upstream Bio, Inc. (NASDAQ:UPB - Free Report) during the 4th quarter, according to its most recent disclosure with the SEC. The institutional investor acquired 7,176,187 shares of the company's stock, valued at approximately $117,977,000. Fmr LLC ownedApril 16, 2025 | marketbeat.comUpstream Bio Stock Price, Quotes and Forecasts | NASDAQ:UPB | BenzingaApril 11, 2025 | benzinga.comUpstream Bio (NASDAQ:UPB) Is In A Good Position To Deliver On Growth PlansApril 11, 2025 | finance.yahoo.comAlliancebernstein L.P. Invests $18.27 Million in Upstream Bio, Inc. (NASDAQ:UPB)Alliancebernstein L.P. bought a new stake in Upstream Bio, Inc. (NASDAQ:UPB - Free Report) in the fourth quarter, according to its most recent 13F filing with the Securities and Exchange Commission (SEC). The institutional investor bought 1,111,337 shares of the company's stock, valued at approximApril 9, 2025 | marketbeat.comWellington Management Group LLP Makes New $25.63 Million Investment in Upstream Bio, Inc. (NASDAQ:UPB)Wellington Management Group LLP bought a new stake in shares of Upstream Bio, Inc. (NASDAQ:UPB - Free Report) in the fourth quarter, according to its most recent Form 13F filing with the Securities & Exchange Commission. The fund bought 1,583,154 shares of the company's stock, valued at approxiApril 9, 2025 | marketbeat.comNorges Bank Invests $16.44 Million in Upstream Bio, Inc. (NASDAQ:UPB)Norges Bank acquired a new stake in Upstream Bio, Inc. (NASDAQ:UPB - Free Report) in the 4th quarter, according to its most recent Form 13F filing with the Securities and Exchange Commission (SEC). The fund acquired 1,000,000 shares of the company's stock, valued at approximately $16,440,000. NorgeApril 9, 2025 | marketbeat.comUpstream Bio, Inc.'s Lock-Up Period Will Expire on April 9th (NASDAQ:UPB)Upstream Bio's (NASDAQ:UPB - Get Free Report) lock-up period is set to end on Wednesday, April 9th. Upstream Bio had issued 15,000,000 shares in its IPO on October 11th. The total size of the offering was $255,000,000 based on an initial share price of $17.00. After the expiration of Upstream Bio's lock-up period, company insiders and major shareholders will be able to sell their shares of the company.April 3, 2025 | marketbeat.comCharles Schwab Investment Management Inc. Invests $2.23 Million in Upstream Bio, Inc. (NASDAQ:UPB)Charles Schwab Investment Management Inc. bought a new stake in Upstream Bio, Inc. (NASDAQ:UPB - Free Report) during the fourth quarter, according to the company in its most recent 13F filing with the SEC. The institutional investor bought 135,323 shares of the company's stock, valued at approximaMarch 30, 2025 | marketbeat.comBank of New York Mellon Corp Invests $607,000 in Upstream Bio, Inc. (NASDAQ:UPB)Bank of New York Mellon Corp purchased a new stake in shares of Upstream Bio, Inc. (NASDAQ:UPB - Free Report) in the 4th quarter, according to its most recent Form 13F filing with the Securities and Exchange Commission. The firm purchased 36,913 shares of the company's stock, valued at approximatelMarch 27, 2025 | marketbeat.comUpstream Bio (NASDAQ:UPB) Stock Price Down 7.3% - Time to Sell?Upstream Bio (NASDAQ:UPB) Trading Down 7.3% - Time to Sell?March 19, 2025 | marketbeat.comWilliam Blair Forecasts Increased Earnings for Upstream BioUpstream Bio, Inc. (NASDAQ:UPB - Free Report) - Stock analysts at William Blair upped their Q1 2025 EPS estimates for shares of Upstream Bio in a research note issued to investors on Wednesday, March 12th. William Blair analyst M. Phipps now forecasts that the company will post earnings per shareMarch 15, 2025 | marketbeat.comUpstream Bio’s Financial Results and Strategic ProgressMarch 13, 2025 | tipranks.comUpstream Bio, Inc. Completes Enrollment in Phase 2 Trial of Verekitug for Chronic Rhinosinusitis and Raises $293 Million in IPOMarch 12, 2025 | quiverquant.comUpstream Bio Reports Fourth Quarter and Full Year 2024 Financial Results and Recent Business HighlightsMarch 12, 2025 | globenewswire.comUPB Upstream Bio, Inc.March 8, 2025 | seekingalpha.comPiper Sandler Remains a Buy on Upstream Bio, Inc. (UPB)March 4, 2025 | markets.businessinsider.comUpstream Bio to Present at Upcoming March Investor ConferencesFebruary 25, 2025 | globenewswire.comUpstream Bio (UPB) Projected to Post Earnings on ThursdayUpstream Bio (NASDAQ:UPB) will be releasing earnings before the market opens on Thursday, February 27, Financial Modeling Prep reports.February 22, 2025 | marketbeat.comUpstream Bio (NASDAQ:UPB) Reaches New 1-Year Low - What's Next?Upstream Bio (NASDAQ:UPB) Hits New 12-Month Low - Here's What HappenedFebruary 5, 2025 | marketbeat.comUpstream Bio (NASDAQ:UPB) Trading Down 7.3% - Time to Sell?Upstream Bio (NASDAQ:UPB) Stock Price Down 7.3% - Time to Sell?February 3, 2025 | marketbeat.comUpstream Bio (NASDAQ:UPB) Stock Price Up 9.4% - Here's What HappenedUpstream Bio (NASDAQ:UPB) Stock Price Up 9.4% - Time to Buy?January 30, 2025 | marketbeat.comMoody Aldrich Partners LLC Makes New Investment in Upstream Bio, Inc. (NASDAQ:UPB)Moody Aldrich Partners LLC purchased a new stake in Upstream Bio, Inc. (NASDAQ:UPB - Free Report) during the fourth quarter, according to its most recent Form 13F filing with the SEC. The fund purchased 74,773 shares of the company's stock, valued at approximately $1,229,000. Moody Aldrich PartnersJanuary 29, 2025 | marketbeat.com Get Upstream Bio News Delivered to You Automatically Sign up to receive the latest news and ratings for UPB and its competitors with MarketBeat's FREE daily newsletter. Email Address UPB Media Mentions By Week UPB Media Sentiment Learn about the media sentiment score. Each headline receives a score ranging from 2 (good news) to -2 (bad news). Our company news sentiment scores track the average news sentiment of articles about each company over the most recent 7 days in order to identify companies that are receiving positive press. UPB News Sentiment▼1.120.87▲Average Medical News Sentiment UPB News Coverage Learn about the media coverage comparison. We track news headlines from hundreds of news outlets and tag them by company. This chart compares the number of articles about this company in the last seven days compared with the average number of articles about this company on a typical week. UPB Articles This Week▼42▲UPB Articles Average Week Get Upstream Bio News Delivered to You Automatically Sign up to receive the latest news and ratings for UPB and its competitors with MarketBeat's FREE daily newsletter. 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