NASDAQ:VYNE VYNE Therapeutics (VYNE) Stock Price, News & Analysis $28.32 -0.24 (-0.82%) Closing price 07/27/2026 07:48 PM EasternExtended Trading$28.32 0.00 (0.00%) As of 07/27/2026 07:48 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsDividendEarningsFDA EventsFinancialsHeadlinesInsider TradesOwnershipSEC FilingsTrendsBuy This Stock About VYNE Therapeutics Stock (NASDAQ:VYNE) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get VYNE Therapeutics alerts:Sign Up Key Stats Today's Range$23.37▼$28.5650-Day Range$25.45▼$46.1752-Week Range$14.03▼$79.75Volume93,278 shsAverage Volume44,151 shsMarket Capitalization$18.98 millionP/E RatioN/ADividend YieldN/APrice TargetN/AConsensus RatingReduce Company Overview VYNE Therapeutics is a clinical-stage biopharmaceutical company focused on the discovery and development of small-molecule therapies for vascular, inflammatory and fibrotic diseases. The company is advancing a pipeline of selective oral inhibitors that modulate key pathways implicated in chronic tissue damage and immune dysregulation. Headquartered in the San Francisco Bay Area, VYNE Therapeutics seeks to address high-unmet-need conditions by leveraging proprietary chemical and biological insights to create differentiated drug candidates. The company’s lead program, VTX-002, targets the colony-stimulating factor-1 receptor (CSF-1R) pathway, which plays a central role in macrophage proliferation and activation. VTX-002 is in IND-enabling studies for indications such as pulmonary fibrosis and other fibrotic disorders. A second discovery program is focused on a novel mechanism of complement modulation, intended to dampen excessive inflammatory responses in vascular and autoimmune diseases. In addition to these core assets, VYNE maintains a discovery engine aimed at identifying new small molecules with optimized drug-like properties for indications in cardiometabolic and fibrotic pathology. Since its founding, VYNE Therapeutics has built a leadership team comprised of seasoned executives and scientific founders with prior experience at leading biotechnology and pharmaceutical companies. The company collaborates with academic institutions and contract research organizations to accelerate preclinical and clinical activities. VYNE’s research and development efforts are designed to serve patient populations across North America and Europe, with strategic plans to expand into additional regions through partnerships and licensing agreements.AI Generated. May Contain Errors. Read More VYNE Therapeutics Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks19th Percentile Overall ScoreVYNE MarketRank™: VYNE Therapeutics scored higher than 19% of companies evaluated by MarketBeat, and ranked 760th out of 832 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion1.0 / 5Analyst RatingReduce Consensus RatingVYNE Therapeutics has received a consensus rating of Reduce. The company's average rating score is 1.50, and is based on no strong buy ratings, no buy ratings, 1 hold rating, and 1 sell rating.Amount of Analyst CoverageVYNE Therapeutics has only been the subject of 1 research reports in the past 90 days.Read more about VYNE Therapeutics' stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthN/A Price to Earnings Ratio vs. the MarketThe P/E ratio of VYNE Therapeutics is -74.54, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of VYNE Therapeutics is -74.54, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioVYNE Therapeutics has a P/B Ratio of 0.68. P/B Ratios below 1 indicate that a company could be undervalued with respect to its assets and liabilities.Read more about VYNE Therapeutics' valuation and earnings. Short Interest3.0 / 5Short Interest LevelHealthy Percentage of Shares Shorted0.57% of the float of VYNE Therapeutics has been sold short.Short Interest Ratio / Days to CoverVYNE Therapeutics has a short interest ratio ("days to cover") of 0.08, which is generally considered an acceptable ratio of short interest to trading volume.Change versus previous monthShort interest in VYNE Therapeutics has recently increased by 76.33%, indicating that investor sentiment is decreasing significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldVYNE Therapeutics does not currently pay a dividend.Dividend GrowthVYNE Therapeutics does not have a long track record of dividend growth. News and Social Media3.3 / 5News Sentiment0.25 News SentimentVYNE Therapeutics has a news sentiment score of 0.25. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.89 average news sentiment score of Medical companies.News Coverage This WeekMarketBeat has tracked 7 news articles for VYNE Therapeutics this week, compared to 1 article on an average week.Search Interest4 people have searched for VYNE on MarketBeat in the last 30 days. MarketBeat Follows1 people have added VYNE Therapeutics to their MarketBeat watchlist in the last 30 days. Company Ownership0.8 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, VYNE Therapeutics insiders have not sold or bought any company stock.Percentage Held by Insiders3.03% of the stock of VYNE Therapeutics is held by insiders.Percentage Held by Institutions83.78% of the stock of VYNE Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about VYNE Therapeutics' insider trading history. 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Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. VYNE Stock News HeadlinesYarrow Bioscience Completes VYNE Therapeutics Merger, Begins Phase 2 Trial Dosing for YB-101July 29 at 6:52 PM | finance.yahoo.comYarrow Bioscience Announces Closing of Merger with VYNE Therapeutics and Initiation of Dosing in Phase 2a/2b Trial of YB-101, a Potential First-in-Class Treatment for Graves ...July 27 at 12:15 PM | finance.yahoo.comElon’s message for AmericaElon Musk bought Super Bowl ad time at $266,000 per second - something he has never done before. 125 million Americans watched, but Whitney Tilson, former manager of a $200 million hedge fund, says most investors missed what it actually means. With 1 in 3 Super Bowl viewers using buy-now-pay-later services and 40% of Americans carrying more credit card debt than savings, Tilson believes Elon's message reveals a major economic current - and a clear signal for where smart money should be positioned.July 30 at 1:00 AM | Stansberry Research (Ad)VYNE Therapeutics Provides Update Regarding Cash Dividend, Reverse Stock Split and Anticipated Timing of Closing of the Proposed Merger with Yarrow BioscienceJuly 23, 2026 | globenewswire.comVYNE Therapeutics (NASDAQ:VYNE) Shares Scheduled to Reverse Split on Monday, July 27thJuly 23, 2026 | americanbankingnews.comVYNE Therapeutics Inc.: VYNE Therapeutics Announces 1-for-50 Reverse Stock Split and Provides Update Regarding Special Dividend in Connection with the Proposed Merger with ...July 22, 2026 | finanznachrichten.deVYNE Therapeutics Announces 1-for-50 Reverse Stock Split and Provides Update Regarding Special Dividend in Connection with the Proposed Merger with Yarrow BioscienceJuly 21, 2026 | globenewswire.comVYNE Therapeutics Announces Special Cash Dividend in Connection with Pending Merger with Yarrow BioscienceJuly 10, 2026 | quiverquant.comQSee More Headlines VYNE Stock Analysis - Frequently Asked Questions How have VYNE shares performed this year? VYNE Therapeutics' stock was trading at $29.0050 at the beginning of 2026. Since then, VYNE stock has decreased by 2.3% and is now trading at $28.3250. How were VYNE Therapeutics' earnings last quarter? VYNE Therapeutics Inc. (NASDAQ:VYNE) released its quarterly earnings data on Friday, May, 15th. The company reported ($4.00) earnings per share for the quarter, beating the consensus estimate of ($9.00) by $5.00. The firm had revenue of $0.09 million for the quarter, compared to analysts' expectations of $0.20 million. VYNE Therapeutics had a negative trailing twelve-month return on equity of 70.42% and a negative net margin of 4,726.21%. When did VYNE Therapeutics' stock split? Shares of VYNE Therapeutics reverse split on Monday, February 13th 2023.The 1-18 reverse split was announced on Monday, February 13th 2023. The number of shares owned by shareholders was adjusted after the closing bell on Monday, February 13th 2023. An investor that had 100 shares of stock prior to the reverse split would have 6 shares after the split. When did VYNE Therapeutics IPO? VYNE Therapeutics (VYNE) raised $116 million in an initial public offering on Thursday, January 25th 2018. The company issued 7,000,000 shares at $16.00-$17.00 per share. How do I buy shares of VYNE Therapeutics? Shares of VYNE stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of VYNE Therapeutics own? Based on aggregate information from My MarketBeat watchlists, some other companies that VYNE Therapeutics investors own include NIO (NIO), Tesla (TSLA), Sorrento Therapeutics (SRNE), Advanced Micro Devices (AMD), Meta Platforms (META), NVIDIA (NVDA). Company Calendar Last Earnings5/15/2026Record date for 7/23 Dividend7/22/2026Dividend Payable7/23/2026Today7/30/2026Next Earnings (Estimated)8/13/2026Fiscal Year End12/31/2026Get Stock AlertsIndustry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry MED - DRUGS Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:VYNE CIK1566044 Webvynetherapeutics.com Phone(800) 755-7936FaxN/AEmployees30Year FoundedN/AProfitability EPS (Trailing Twelve Months)($0.38) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$26.48 million Net Margins-4,726.21% Pretax Margin-4,782.82% Return on Equity-70.42% Return on Assets-63.46% Debt Debt-to-Equity RatioN/A Current Ratio20.86 Quick Ratio20.86 Sales & Book Value Annual Sales$570 thousand Price / Sales33.29 Cash FlowN/A Price / Cash FlowN/A Book Value$41.71 per share Price / Book0.68Miscellaneous Outstanding Shares670,000Free Float648,000Market Cap$18.98 million OptionableNot Optionable Beta2.00 Social Links The Infrastructure's Backbone: 10 Stocks Powering the AI BuildoutThe AI boom extends far beyond the biggest tech names. Discover 10 companies supplying the memory, storage, networking, semiconductor manufacturing, and power infrastructure that make AI possible. Learn where the next wave of AI investment opportunities may emerge—and the key risks investors should watch as the global AI buildout accelerates.Get This Free Report This page (NASDAQ:VYNE) was last updated on 7/30/2026 by MarketBeat.com Staff. From Our PartnersPass by August 7… or wait until 2027?Right now, your phone is recording exactly where you are. It does this roughly every two minutes. 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