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OTCMKTS:OPHLF

Ono Pharmaceutical (OPHLF) Stock Price, News & Analysis

Ono Pharmaceutical logo
$14.71 -0.15 (-1.01%)
As of 10:04 AM Eastern

About Ono Pharmaceutical Stock (OTCMKTS:OPHLF)

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Key Stats

Today's Range
$14.71
$14.97
50-Day Range
$13.38
$15.56
52-Week Range
$10.27
$18.67
Volume
345 shs
Average Volume
667 shs
Market Capitalization
$6.91 billion
P/E Ratio
14.01
Dividend Yield
N/A
Price Target
N/A
Consensus Rating
Strong Buy

Company Overview

Ono Pharmaceutical Co., Ltd., founded in 1717 and headquartered in Osaka, Japan, is a research‐based pharmaceutical company specializing in the discovery, development and marketing of innovative therapies. With origins as a traditional pharmacy, Ono has grown into a global biopharmaceutical entity focused on delivering new treatment options across several therapeutic areas, including oncology, immunology, cardiovascular and antiviral diseases. The company conducts comprehensive research programs spanning early drug discovery through to clinical development.

One of Ono’s most recognized products is the immune checkpoint inhibitor nivolumab, marketed in collaboration with Bristol-Myers Squibb under the trade name Opdivo. This immuno-oncology therapy has become a cornerstone treatment for various cancers such as melanoma, lung and renal cell carcinoma. Beyond oncology, Ono has developed epoprostenol (marketed as FASPRO) for pulmonary arterial hypertension and pursues research in autoimmune diseases and infectious disease treatments, including antiviral candidates.

Ono operates a network of research facilities and subsidiaries across Asia, North America and Europe to support its global R&D and commercial activities. In Japan, the company’s main research center focuses on molecular biology and immunology, while its U.S. and European research arms conduct clinical trials and regulatory submissions. This international footprint enables Ono to collaborate with academic institutions, biotechnology firms and multinational pharmaceutical partners.

Governed by a board of directors and led by senior executives with extensive industry experience, Ono maintains a strategic emphasis on innovation and partnership. The company continues to expand its pipeline through in‐house discovery and external collaborations, aiming to address unmet medical needs and enhance patient outcomes worldwide.

AI Generated. May Contain Errors.

Ono Pharmaceutical Stock Analysis - MarketRank™

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2nd Percentile Overall Score

OPHLF MarketRank™: 

Ono Pharmaceutical scored higher than 2% of companies evaluated by MarketBeat. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

  • Earnings Growth

    Earnings for Ono Pharmaceutical are expected to decrease by -9.00% in the coming year, from $1.00 to $0.91 per share.

  • Price to Earnings Ratio vs. the Market

    The P/E ratio of Ono Pharmaceutical is 14.01, which means that it is trading at a less expensive P/E ratio than the market average P/E ratio of about 39.69.

  • Price to Earnings Ratio vs. Sector

    The P/E ratio of Ono Pharmaceutical is 14.01, which means that it is trading at a less expensive P/E ratio than the Healthcare sector average P/E ratio of about 268.76.

  • Price to Book Value per Share Ratio

    Ono Pharmaceutical has a P/B Ratio of 1.33. P/B Ratios below 3 indicates that a company is reasonably valued with respect to its assets and liabilities.

  • Read more about Ono Pharmaceutical's valuation and earnings.
  • Percentage of Shares Shorted

    0.76% of the float of Ono Pharmaceutical has been sold short.
  • Short Interest Ratio / Days to Cover

    Ono Pharmaceutical has a short interest ratio ("days to cover") of 999.99, which indicates bearish sentiment.
  • Change versus previous month

    Short interest in Ono Pharmaceutical has recently increased by 51.28%, indicating that investor sentiment is decreasing significantly.
  • Dividend Yield

    Ono Pharmaceutical does not currently pay a dividend.

  • Dividend Growth

    Ono Pharmaceutical does not have a long track record of dividend growth.

  • News Sentiment

    Ono Pharmaceutical has a news sentiment score of -1.00. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.67 average news sentiment score of Healthcare companies.
  • News Coverage This Week

    MarketBeat has tracked 1 news article for Ono Pharmaceutical this week, compared to 0 articles on an average week.
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OPHLF Stock News Headlines

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OPHLF Stock Analysis - Frequently Asked Questions

Ono Pharmaceutical's stock was trading at $12.8696 at the start of the year. Since then, OPHLF shares have increased by 14.3% and is now trading at $14.71.

Ono Pharmaceutical Co. (OTCMKTS:OPHLF) released its quarterly earnings results on Monday, February, 2nd. The company reported $0.40 earnings per share for the quarter, beating analysts' consensus estimates of $0.29 by $0.11. The company had revenue of $892.70 million for the quarter, compared to analyst estimates of $727.58 million. Ono Pharmaceutical had a net margin of 15.02% and a trailing twelve-month return on equity of 9.69%.

Shares of OPHLF stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

Company Calendar

Last Earnings
2/02/2026
Today
8/12/2026
Next Earnings (Estimated)
10/29/2026
Fiscal Year End
3/31/2027

Industry, Sector and Symbol

Stock Exchange
OTCMKTS
Industry
Pharmaceuticals
Sub-Industry
Pharmaceuticals
Current Symbol
OTCMKTS:OPHLF
CIK
940821
Employees
4,287
Year Founded
1717

Profitability

EPS (Trailing Twelve Months)
$1.05
Trailing P/E Ratio
14.01
Forward P/E Ratio
14.71
P/E Growth
N/A
Net Income
$463.46 million
Net Margins
15.02%
Pretax Margin
N/A
Return on Equity
9.69%
Return on Assets
7.50%

Debt

Debt-to-Equity Ratio
0.10
Current Ratio
3.02
Quick Ratio
2.56

Sales & Book Value

Annual Sales
$3.43 billion
Price / Sales
2.02
Cash Flow
$1.07 per share
Price / Cash Flow
13.79
Book Value
$11.07 per share
Price / Book
1.33

Miscellaneous

Outstanding Shares
469,910,000
Free Float
N/A
Market Cap
$6.91 billion
Optionable
Not Optionable
Beta
0.33

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This page (OTCMKTS:OPHLF) was last updated on 8/12/2026 by MarketBeat.com Staff.
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