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Casdin Capital, LLC Top Holdings and 13F Report (2021)

About Casdin Capital, LLC

Investment Activity

  • Casdin Capital, LLC has $1.10 billion in total holdings as of September 30, 2021.
  • Casdin Capital, LLC owns shares of 33 different stocks, but just 8 companies or ETFs make up 80% of its holdings.
  • Approximately 3.45% of the portfolio was purchased this quarter.
  • About 18.26% of the portfolio was sold this quarter.
  • This quarter, Casdin Capital, LLC has purchased 44 new stocks and bought additional shares in 9 stocks.
  • Casdin Capital, LLC sold shares of 12 stocks and completely divested from 12 stocks this quarter.

Largest Holdings

GeneDx
$323,746,309
BioLife Solutions
$166,012,334
Standard BioTools
$91,290,763
Illumina
$61,539,450

Largest New Holdings this Quarter

532457108 - Eli Lilly and Company
$6,626,005 Holding

Largest Purchases this Quarter

Structure Therapeutics
525,000 shares (about $10.89M)
Relay Therapeutics
2,300,000 shares (about $7.96M)
Eli Lilly and Company
8,500 shares (about $6.63M)
Illumina
50,000 shares (about $4.77M)
Prime Medicine
1,200,000 shares (about $2.96M)

Largest Sales this Quarter

Revolution Medicines
810,000 shares (about $29.80M)
BioLife Solutions
1,000,000 shares (about $21.54M)
Exact Sciences
315,000 shares (about $16.74M)
Alnylam Pharmaceuticals
38,500 shares (about $12.55M)
Guardant Health
150,000 shares (about $7.81M)

Sector Allocation Over Time

Map of 500 Largest Holdings ofCasdin Capital, LLC

 
 
Selling
 
 
Neutral
 
 
Buying
Issuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSector
GeneDx Holdings Corp. stock logo
WGS
GeneDx
$323,746,3090.0%3,507,16429.5%Medical
BioLife Solutions, Inc. stock logo
BLFS
BioLife Solutions
$166,012,334$21,540,000 -11.5%7,707,16515.1%Medical
Revolution Medicines, Inc. stock logo
RVMD
Revolution Medicines
$106,247,055$29,799,900 -21.9%2,887,9339.7%Medical
Standard BioTools Inc. stock logo
LAB
Standard BioTools
$91,290,7630.0%76,075,6368.3%Medical
Illumina, Inc. stock logo
ILMN
Illumina
$61,539,450$4,770,500 8.4%645,0005.6%Medical
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
$50,410,000$7,668,000 -13.2%1,775,0004.6%Medical
Verve Therapeutics, Inc. stock logo
VERV
Verve Therapeutics
$45,993,262$1,123,000 2.5%4,095,5714.2%Medical
Relay Therapeutics, Inc. stock logo
RLAY
Relay Therapeutics
$39,439,066$7,958,000 25.3%11,398,5743.6%Medical
Alnylam Pharmaceuticals, Inc. stock logo
ALNY
Alnylam Pharmaceuticals
$26,576,335$12,554,465 -32.1%81,5002.4%Medical
Structure Therapeutics Inc. Sponsored ADR stock logo
GPCR
Structure Therapeutics
$25,406,500$10,888,500 75.0%1,225,0002.3%Medical
Beam Therapeutics Inc. stock logo
BEAM
Beam Therapeutics
$24,664,500$415,690 1.7%1,450,0002.2%Medical
NEUROGENE INC
$19,365,6470.0%1,295,3611.8%COM
Codexis, Inc. stock logo
CDXS
Codexis
$17,568,000$2,196,000 -11.1%7,200,0001.6%Medical
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
$16,930,659$1,527,269 9.9%990,0971.5%Medical
Denali Therapeutics Inc. stock logo
DNLI
Denali Therapeutics
$12,451,100$1,399,000 -10.1%890,0001.1%Medical
Hims & Hers Health, Inc. stock logo
HIMS
Hims & Hers Health
$11,465,500$1,495,500 15.0%230,0001.0%Medical
MAZE THERAPEUTICS INC
$9,311,175$2,300,625 -19.8%758,8570.8%COM
Veracyte, Inc. stock logo
VCYT
Veracyte
$7,468,6050.0%276,3080.7%Medical
Eli Lilly and Company stock logo
LLY
Eli Lilly and Company
$6,626,005$6,626,005 New Holding8,5000.6%Medical
Syndax Pharmaceuticals, Inc. stock logo
SNDX
Syndax Pharmaceuticals
$6,084,000$140,400 2.4%650,0000.6%Medical
SEPTERNA INC
$5,848,0430.0%553,2680.5%COM
Guardant Health, Inc. stock logo
GH
Guardant Health
$5,204,000$7,806,000 -60.0%100,0000.5%Medical
Exact Sciences Corporation stock logo
EXAS
Exact Sciences
$4,782,600$16,739,100 -77.8%90,0000.4%Medical
Prime Medicine, Inc. stock logo
PRME
Prime Medicine
$3,870,922$2,964,000 326.8%1,567,1750.4%Medical
Agios Pharmaceuticals, Inc. stock logo
AGIO
Agios Pharmaceuticals
$3,326,000$4,989,000 -60.0%100,0000.3%Medical
Absci Corporation stock logo
ABSI
Absci
$2,501,2780.0%973,2600.2%Medical
Pacific Biosciences of California, Inc. stock logo
PACB
Pacific Biosciences of California
$897,4710.0%723,7670.1%Medical
Recursion Pharmaceuticals, Inc. stock logo
RXRX
Recursion Pharmaceuticals
$836,5340.0%165,3230.1%Medical
Century Therapeutics, Inc. stock logo
IPSC
Century Therapeutics
$686,190$1,108,532 -61.8%1,228,1900.1%Medical
CONTINEUM THERAPEUTICS INC
$588,8820.0%148,3330.1%CL A
GINKGO BIOWORKS HOLDINGS INC
$410,5460.0%36,4930.0%CL A NEW
Monte Rosa Therapeutics, Inc. stock logo
GLUE
Monte Rosa Therapeutics
$387,9230.0%86,0140.0%Medical
Tenaya Therapeutics, Inc. stock logo
TNYA
Tenaya Therapeutics
$221,235$3,893,948 -94.6%361,9690.0%Medical
Blueprint Medicines Corporation stock logo
BPMC
Blueprint Medicines
$0$28,887,717 -100.0%00.0%Medical
Intellia Therapeutics, Inc. stock logo
NTLA
Intellia Therapeutics
$0$14,220,000 -100.0%00.0%Medical
BeiGene, Ltd. stock logo
BGNE
BeiGene
$0$10,886,800 -100.0%00.0%Medical
2seventy bio, Inc. stock logo
TSVT
2seventy bio
$0$9,880,000 -100.0%00.0%Medical
GE HealthCare Technologies Inc. stock logo
GEHC
GE HealthCare Technologies
$0$8,071,000 -100.0%00.0%Medical
Moderna, Inc. stock logo
MRNA
Moderna
$0$6,378,750 -100.0%00.0%Medical
Verastem, Inc. stock logo
VSTM
Verastem
$0$3,618,000 -100.0%00.0%Medical
Solid Biosciences Inc. stock logo
SLDB
Solid Biosciences
$0$2,867,500 -100.0%00.0%Medical
Teladoc Health, Inc. stock logo
TDOC
Teladoc Health
$0$2,388,000 -100.0%00.0%Medical
DYNE THERAPEUTICS INC
$0$1,046,000 -100.0%00.0%COM
Tango Therapeutics, Inc. stock logo
TNGX
Tango Therapeutics
$0$171,250 -100.0%00.0%Medical
Kronos Bio, Inc. stock logo
KRON
Kronos Bio
$0$102,167 -100.0%00.0%Medical

Showing largest 100 holdings. View all holdings.
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