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Casdin Capital, LLC Top Holdings and 13F Report (2021)

About Casdin Capital, LLC

Investment Activity

  • Casdin Capital, LLC has $1.22 billion in total holdings as of September 30, 2021.
  • Casdin Capital, LLC owns shares of 44 different stocks, but just 11 companies or ETFs make up 80% of its holdings.
  • Approximately 4.59% of the portfolio was purchased this quarter.
  • About 5.11% of the portfolio was sold this quarter.
  • This quarter, Casdin Capital, LLC has purchased 38 new stocks and bought additional shares in 4 stocks.
  • Casdin Capital, LLC sold shares of 11 stocks and completely divested from 2 stocks this quarter.

Largest Holdings

GeneDx
$310,611,980
BioLife Solutions
$198,871,649
Standard BioTools
$82,161,687

Largest New Holdings this Quarter

07725L102 - BeiGene
$10,886,800 Holding
578784100 - MAZE THERAPEUTICS INC
$10,419,391 Holding
36266G107 - GE HealthCare Technologies
$8,071,000 Holding
433000106 - Hims & Hers Health
$5,910,000 Holding
92337C203 - Verastem
$3,618,000 Holding

Largest Purchases this Quarter

BeiGene
40,000 shares (about $10.89M)
MAZE THERAPEUTICS INC
946,357 shares (about $10.42M)
GE HealthCare Technologies
100,000 shares (about $8.07M)
Hims & Hers Health
200,000 shares (about $5.91M)
Standard BioTools
4,820,959 shares (about $5.21M)

Largest Sales this Quarter

Illumina
155,000 shares (about $12.30M)
Sarepta Therapeutics
172,717 shares (about $11.02M)
Exact Sciences
245,000 shares (about $10.61M)
Alnylam Pharmaceuticals
20,000 shares (about $5.40M)
Guardant Health
100,000 shares (about $4.26M)

Sector Allocation Over Time

Map of 500 Largest Holdings ofCasdin Capital, LLC

 
 
Selling
 
 
Neutral
 
 
Buying
Issuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSector
GeneDx Holdings Corp. stock logo
WGS
GeneDx
$310,611,9800.0%3,507,16425.4%Medical
BioLife Solutions, Inc. stock logo
BLFS
BioLife Solutions
$198,871,6490.0%8,707,16516.3%Medical
Revolution Medicines, Inc. stock logo
RVMD
Revolution Medicines
$130,758,911$47,736 0.0%3,697,93310.7%Medical
Standard BioTools Inc. stock logo
LAB
Standard BioTools
$82,161,687$5,206,636 6.8%76,075,6366.7%Medical
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
$60,368,4000.0%2,045,0004.9%Medical
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
$57,487,971$11,022,799 -16.1%900,7834.7%Medical
Illumina, Inc. stock logo
ILMN
Illumina
$47,207,300$12,297,700 -20.7%595,0003.9%Medical
Alnylam Pharmaceuticals, Inc. stock logo
ALNY
Alnylam Pharmaceuticals
$32,402,400$5,400,400 -14.3%120,0002.6%Medical
Blueprint Medicines Co. stock logo
BPMC
Blueprint Medicines
$28,887,7170.0%326,3782.4%Medical
Beam Therapeutics Inc. stock logo
BEAM
Beam Therapeutics
$27,841,226$3,428,726 14.0%1,425,5622.3%Medical
Relay Therapeutics, Inc. stock logo
RLAY
Relay Therapeutics
$23,838,264$393,000 1.7%9,098,5741.9%Medical
Codexis, Inc. stock logo
CDXS
Codexis
$21,789,0000.0%8,100,0001.8%Medical
Verve Therapeutics, Inc. stock logo
VERV
Verve Therapeutics
$18,259,7590.0%3,995,5711.5%Medical
Exact Sciences Co. stock logo
EXAS
Exact Sciences
$17,532,450$10,606,050 -37.7%405,0001.4%Medical
NEUROGENE INC
$15,168,6770.0%1,295,3611.2%COM
Intellia Therapeutics, Inc. stock logo
NTLA
Intellia Therapeutics
$14,220,0000.0%2,000,0001.2%Medical
Denali Therapeutics Inc. stock logo
DNLI
Denali Therapeutics
$13,459,0500.0%990,0001.1%Medical
Structure Therapeutics Inc. stock logo
GPCR
Structure Therapeutics
$12,117,0000.0%700,0001.0%Medical
BeiGene, Ltd. stock logo
BGNE
BeiGene
$10,886,800$10,886,800 New Holding40,0000.9%Medical
Guardant Health, Inc. stock logo
GH
Guardant Health
$10,650,000$4,260,000 -28.6%250,0000.9%Medical
MAZE THERAPEUTICS INC
$10,419,391$10,419,391 New Holding946,3570.9%COM
2seventy bio, Inc. stock logo
TSVT
2seventy bio
$9,880,0000.0%2,000,0000.8%Medical
Veracyte, Inc. stock logo
VCYT
Veracyte
$8,192,5320.0%276,3080.7%Medical
GE HealthCare Technologies Inc. stock logo
GEHC
GE HealthCare Technologies
$8,071,000$8,071,000 New Holding100,0000.7%Medical
Syndax Pharmaceuticals, Inc. stock logo
SNDX
Syndax Pharmaceuticals
$7,800,975$1,965,600 33.7%635,0000.6%Medical
Agios Pharmaceuticals, Inc. stock logo
AGIO
Agios Pharmaceuticals
$7,325,0000.0%250,0000.6%Medical
Moderna, Inc. stock logo
MRNA
Moderna
$6,378,750$3,543,750 -35.7%225,0000.5%Medical
Hims & Hers Health, Inc. stock logo
HIMS
Hims & Hers Health
$5,910,000$5,910,000 New Holding200,0000.5%Medical
Tenaya Therapeutics, Inc. stock logo
TNYA
Tenaya Therapeutics
$3,838,4670.0%6,732,9710.3%Medical
Verastem, Inc. stock logo
VSTM
Verastem
$3,618,000$3,618,000 New Holding600,0000.3%Medical
SEPTERNA INC
$3,203,4220.0%553,2680.3%COM
Solid Biosciences Inc. stock logo
SLDB
Solid Biosciences
$2,867,500$2,867,500 New Holding775,0000.2%Medical
Absci Co. stock logo
ABSI
Absci
$2,442,8830.0%973,2600.2%Medical
Teladoc Health, Inc. stock logo
TDOC
Teladoc Health
$2,388,000$2,388,000 New Holding300,0000.2%Medical
Century Therapeutics, Inc. stock logo
IPSC
Century Therapeutics
$1,529,062$941,618 -38.1%3,212,3160.1%Medical
DYNE THERAPEUTICS INC
$1,046,000$1,046,000 New Holding100,0000.1%COM
CONTINEUM THERAPEUTICS INC
$1,035,364$1,035,364 -50.0%148,3330.1%CL A
Recursion Pharmaceuticals, Inc. stock logo
RXRX
Recursion Pharmaceuticals
$874,5590.0%165,3230.1%Medical
Pacific Biosciences of California, Inc. stock logo
PACB
Pacific Biosciences of California
$854,045$368,269 -30.1%723,7670.1%Medical
Prime Medicine, Inc. stock logo
PRME
Prime Medicine
$730,6780.0%367,1750.1%Medical
Monte Rosa Therapeutics, Inc. stock logo
GLUE
Monte Rosa Therapeutics
$399,1050.0%86,0140.0%Medical
GINKGO BIOWORKS HOLDINGS INC
$208,0100.0%36,4930.0%CL A NEW
Tango Therapeutics, Inc. stock logo
TNGX
Tango Therapeutics
$171,250$1,456,788 -89.5%125,0000.0%Medical
Kronos Bio, Inc. stock logo
KRON
Kronos Bio
$102,1670.0%123,8390.0%Medical
4D Molecular Therapeutics, Inc. stock logo
FDMT
4D Molecular Therapeutics
$0$6,405,500 -100.0%00.0%Medical
Fortrea Holdings Inc. stock logo
FTRE
Fortrea
$0$5,128,750 -100.0%00.0%Medical

Showing largest 100 holdings. View all holdings.
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