Octagon Capital Advisors Lp Top Holdings and 13F Report (2026) About Octagon Capital Advisors LpInvestment ActivityOctagon Capital Advisors Lp has $1.11 billion in total holdings as of June 30, 2026.Octagon Capital Advisors Lp owns shares of 27 different stocks, but just 11 companies or ETFs make up 80% of its holdings.Approximately 13.40% of the portfolio was purchased this quarter.About 15.32% of the portfolio was sold this quarter.This quarter, Octagon Capital Advisors Lp has purchased 29 new stocks and bought additional shares in 4 stocks.Octagon Capital Advisors Lp sold shares of 6 stocks and completely divested from 7 stocks this quarter.Largest Holdings DIANTHUS THERAPEUTICS INC $179,525,699DEFINIUM THERAPEUTICS INC $138,768,000ABIVAX SA $132,327,180Cogent Biosciences $90,945,000ALUMIS INC $79,655,898 Largest New Holdings this Quarter 29479A908 - ERASCA INC $22,991,600 Holding86627T108 - Summit Therapeutics $18,212,500 Holding00704R109 - ADLAI NORTYE LTD $10,749,234 Holding81728A207 - FAETH THERAPEUTICS INC $9,025,250 Holding403783103 - GYRE THERAPEUTICS INC $6,289,601 Holding Largest Purchases this Quarter ABIVAX SA 316,000 shares (about $42.11M)DEFINIUM THERAPEUTICS INC 510,000 shares (about $23.99M)ERASCA INC 1,255,000 shares (about $22.99M)Summit Therapeutics 1,250,000 shares (about $18.21M)ADLAI NORTYE LTD 934,716 shares (about $10.75M) Largest Sales this Quarter Trevi Therapeutics 1,170,000 shares (about $21.82M)Kymera Therapeutics 115,000 shares (about $13.19M)Ocular Therapeutix 1,091,600 shares (about $10.72M)DIANTHUS THERAPEUTICS INC 105,000 shares (about $10.24M)PRECISION BIOSCIENCES INC 886,732 shares (about $6.97M) Sector Allocation Over TimeMap of 500 Largest Holdings ofOctagon Capital Advisors Lp Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorDIANTHUS THERAPEUTICS INC$179,525,699$10,235,400 â–¼-5.4%1,841,66716.1%COMDEFINIUM THERAPEUTICS INC$138,768,000$23,990,400 â–²20.9%2,950,00012.5%COM SHSABIVAX SA$132,327,180$42,110,160 â–²46.7%993,00011.9%SPONSORED ADSCOGTCogent Biosciences$90,945,0000.0%2,350,0008.2%HealthcareALUMIS INC$79,655,8980.0%2,830,7007.2%COMARRIVENT BIOPHARMA INC$68,474,4160.0%1,971,0546.2%COMTSHATaysha Gene Therapies$66,010,992$5,674,998 â–²9.4%9,693,2445.9%HealthcareBIOAGE LABS INC$42,843,4800.0%1,748,0003.9%COMMIRMMirum Pharmaceuticals$39,675,0230.0%338,9003.6%HealthcareKYMRKymera Therapeutics$35,547,700$13,187,050 â–¼-27.1%310,0003.2%HealthcareAKTIS ONCOLOGY INC$30,968,0990.0%960,8472.8%COMXENEXenon Pharmaceuticals$29,576,4000.0%490,0002.7%HealthcareERASCA INC$22,991,600$22,991,600 â–²New Holding1,255,0002.1%CALLPALISADE BIO INC$21,477,5030.0%10,276,3171.9%COMOCULOcular Therapeutix$20,376,500$10,719,512 â–¼-34.5%2,075,0001.8%HealthcareIRONDisc Medicine$19,747,8000.0%270,0001.8%HealthcareSMMTSummit Therapeutics$18,212,500$18,212,500 â–²New Holding1,250,0001.6%HealthcarePHVSPharvaris$15,793,412$10,087,712 â–²176.8%456,7211.4%HealthcareADLAI NORTYE LTD$10,749,234$10,749,234 â–²New Holding934,7161.0%SPONSORED ADSPRECISION BIOSCIENCES INC$10,611,000$6,969,714 â–¼-39.6%1,350,0001.0%COM NEWDBV TECHNOLOGIES S A$9,416,8800.0%574,2000.8%SPONSORED ADSFAETH THERAPEUTICS INC$9,025,250$9,025,250 â–²New Holding361,0100.8%COM NEWGYRE THERAPEUTICS INC$6,289,601$6,289,601 â–²New Holding954,4160.6%COMTRVITrevi Therapeutics$5,874,750$21,820,500 â–¼-78.8%315,0000.5%HealthcareUNICYCIVE THERAPEUTICS INC$4,690,0000.0%1,000,0000.4%COM NEWCNTXContext Therapeutics$1,689,395$1,218,580 â–¼-41.9%3,050,0000.2%HealthcareGOSSGossamer Bio$1,275,6500.0%7,750,0000.1%HealthcareCNTACentessa Pharmaceuticals$0$29,790,000 â–¼-100.0%00.0%HealthcareKALVKalVista Pharmaceuticals$0$29,188,500 â–¼-100.0%00.0%HealthcareTERNTerns Pharmaceuticals$0$27,941,600 â–¼-100.0%00.0%HealthcareBRIDGEBIO ONCOLOGY THERAPEUT$0$6,435,050 â–¼-100.0%00.0%COM NEWLEXEO THERAPEUTICS INC$0$6,314,000 â–¼-100.0%00.0%COMPERSPECTIVE THERAPEUTICS INC$0$3,300,784 â–¼-100.0%00.0%COM NEWEVOMMUNE INC$0$3,298,421 â–¼-100.0%00.0%COM SHSShowing largest 100 holdings. View all holdings. More Institutional Buying and Selling Information SEC Filings and Trading Data SEC Filings 13F Filings Top 13F Buys Top 13F Sells Unlock superior investment research and tools. Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools and reports. Get MarketBeat All Access MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. Real-time analyst ratings, insider transactions, earnings data, and more. Our daily ratings and market update email newsletter. Sign in to your free account to enjoy all that MarketBeat has to offer. Sign In Create Account Your Email Address: Email Address Required Your Password: Password Required Log In Email Me a Login Link or Sign in with Facebook Sign in with Google Forgot your password? Your Email Address: Please enter your email address. Please enter a valid email address Choose a Password: Please enter your password. Your password must be at least 8 characters long and contain at least 1 number, 1 letter, and 1 special character. Create My Account (Free) or Sign in with Facebook Sign in with Google By creating a free account, you agree to our terms of service. This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.