Stonepine Capital Management, LLC Top Holdings and 13F Report (2021) About Stonepine Capital Management, LLCInvestment ActivityStonepine Capital Management, LLC has $102.76 million in total holdings as of September 30, 2021.Stonepine Capital Management, LLC owns shares of 66 different stocks, but just 19 companies or ETFs make up 80% of its holdings.Approximately 23.87% of the portfolio was purchased this quarter.About 17.44% of the portfolio was sold this quarter.This quarter, Stonepine Capital Management, LLC has purchased 52 new stocks and bought additional shares in 18 stocks.Stonepine Capital Management, LLC sold shares of 24 stocks and completely divested from 9 stocks this quarter.Largest Holdings ANI Pharmaceuticals $13,648,925Evolus $13,648,925OPTINOSE INC $7,231,893Zevra Therapeutics $4,868,500Verastem $3,696,390 Largest New Holdings this Quarter 27966L306 - EDESA BIOTECH INC $1,677,500 Holding492327101 - Keros Therapeutics $1,019,000 Holding374163103 - Geron $795,000 Holding88427A107 - TF Financial $738,357 Holding00439U104 - GRACE THERAPEUTICS INC $665,683 Holding Largest Purchases this Quarter ANI Pharmaceuticals 27,600 shares (about $7.85M)OPTINOSE INC 199,990 shares (about $1.83M)SURROZEN INC 148,582 shares (about $1.73M)EDESA BIOTECH INC 687,500 shares (about $1.68M)Enanta Pharmaceuticals 258,842 shares (about $1.43M) Largest Sales this Quarter Galapagos 106,032 shares (about $2.66M)Evolus 130,077 shares (about $1.56M)Verastem 257,000 shares (about $1.55M)scPharmaceuticals 335,843 shares (about $883.27K)INOVIO PHARMACEUTICALS INC 531,669 shares (about $866.62K) Sector Allocation Over TimeMap of 500 Largest Holdings ofStonepine Capital Management, LLC Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorANIPANI Pharmaceuticals$13,648,925$7,848,132 ▲135.3%48,00013.3%MedicalEOLSEvolus$13,648,925$1,564,826 ▼-10.3%1,134,57413.3%MedicalOPTINOSE INC$7,231,893$1,833,908 ▲34.0%788,6477.0%COM NEWZVRAZevra Therapeutics$4,868,500$391,727 ▲8.8%650,0004.7%MedicalVSTMVerastem$3,696,390$1,549,710 ▼-29.5%613,0003.6%MedicalURGNUroGen Pharma$3,687,404$100,381 ▲2.8%333,4003.6%MedicalSURROZEN INC$3,332,218$1,732,466 ▲108.3%285,7823.2%COM NEWENTAEnanta Pharmaceuticals$3,260,896$1,428,808 ▲78.0%590,7423.2%MedicalANIKAnika Therapeutics$3,260,896$498,400 ▼-13.3%206,6393.2%MedicalAQSTAquestive Therapeutics$3,039,973$607,995 ▲25.0%200,0003.0%MedicalESTAEstablishment Labs$3,039,973$224,509 ▼-6.9%74,5003.0%MedicalINDVIndivior$2,897,120$9,530 ▼-0.3%304,0002.8%MedicalACRSAclaris Therapeutics$2,766,143$710,415 ▼-20.4%527,8422.7%MedicalDAWNDay One Biopharmaceuticals$2,766,143$902,593 ▲48.4%348,8202.7%MedicalXOMAXOMA$2,587,173$81,972 ▲3.3%129,8132.5%MedicalTELATELA Bio$2,507,375$363,406 ▼-12.7%2,055,2252.4%MedicalGLPGGalapagos$2,360,476$2,663,524 ▼-53.0%93,9682.3%MedicalIKTInhibikase Therapeutics$2,003,791$476,139 ▼-19.2%914,9731.9%MedicalHRTXHeron Therapeutics$1,751,420$211,420 ▲13.7%796,1001.7%MedicalEDESA BIOTECH INC$1,677,500$1,677,500 ▲New Holding687,5001.6%COM NEWMYOMyomo$1,330,961$10,972 ▲0.8%276,7071.3%MedicalKROSKeros Therapeutics$1,019,000$1,019,000 ▲New Holding100,0001.0%MedicalVIRVir Biotechnology$937,189$126,217 ▼-11.9%144,6280.9%MedicalSCPHscPharmaceuticals$914,417$883,267 ▼-49.1%347,6870.9%MedicalINOVIO PHARMACEUTICALS INC$844,880$866,621 ▼-50.6%518,3310.8%COM SHSPROFProfound Medical$814,462$349,537 ▼-30.0%139,9420.8%MedicalGERNGeron$795,000$795,000 ▲New Holding500,0000.8%MedicalAYTUAytu BioPharma$795,000$96,301 ▲13.8%463,7210.8%MedicalTHRDTF Financial$738,357$738,357 ▲New Holding212,7830.7%MedicalPMVPPMV Pharmaceuticals$686,899$102,872 ▲17.6%630,1830.7%MedicalGRACE THERAPEUTICS INC$665,683$665,683 ▲New Holding294,5500.6%COMITOSiTeos Therapeutics$656,7000.0%110,0000.6%MedicalCOLLCollegium Pharmaceutical$615,119$615,119 ▲New Holding20,6070.6%MedicalCALCCalciMedica$615,119$169,819 ▼-21.6%367,3710.6%MedicalKIORA PHARMACEUTICALS INC$603,947$972 ▼-0.2%200,6470.6%COMYMABY-mAbs Therapeutics$581,039$581,039 ▲New Holding131,1600.6%MedicalXERSXeris Biopharma$561,435$439,486 ▼-43.9%102,2650.5%MedicalCHRSCoherus BioSciences$500,815$299,065 ▲148.2%620,5880.5%MedicalKEZAR LIFE SCIENCES INC$488,000$48,800 ▼-9.1%100,0000.5%COM NEWSLRNAcelyrin$413,923$85,734 ▲26.1%167,5800.4%MedicalIMABI-Mab$398,477$398,477 ▲New Holding483,6470.4%MedicalSEPTERNA INC$394,206$394,206 ▲New Holding68,0840.4%COMHLVXHilleVax$346,478$154,575 ▲80.5%238,9500.3%MedicalXGNExagen$343,732$557,535 ▼-61.9%95,7470.3%MedicalRNXTRenovoRx$275,406$275,406 ▲New Holding278,1880.3%MedicalKALVKalVista Pharmaceuticals$248,687$248,687 ▲New Holding21,5500.2%MedicalACETAdicet Bio$203,500$76,767 ▼-27.4%508,2660.2%MedicalCARGO THERAPEUTICS INC$203,500$203,500 ▲New Holding50,0000.2%COMMISTMilestone Pharmaceuticals$200,025$200,025 ▼-50.0%250,0000.2%MedicalBIOAGE LABS INC$188,000$188,000 ▲New Holding50,0000.2%COMACADACADIA Pharmaceuticals$185,850$251,945 ▼-57.5%93,3930.2%MedicalCRBPCorbus Pharmaceuticals$185,850$185,850 ▲New Holding35,0000.2%MedicalVNDAVanda Pharmaceuticals$161,329$46,579 ▲40.6%35,1480.2%MedicalPOLYPID LTD$148,982$131,958 ▼-47.0%54,9750.1%COMAMRNAmarin$105,000$86,589 ▲470.3%651,6140.1%MedicalELANElanco Animal Health$105,000$105,000 ▲New Holding10,0000.1%MedicalZNTLZentalis Pharmaceuticals$95,400$95,400 ▲New Holding60,0000.1%MedicalAADIAadi Bioscience$83,122$83,122 ▲New Holding46,6980.1%MedicalSVRASavara$80,549$80,549 ▲New Holding29,0790.1%MedicalIOVAIovance Biotherapeutics$66,600$66,600 ▲New Holding20,0000.1%MedicalTHERATECHNOLOGIES INC$36,155$36,155 ▲New Holding25,8250.0%COM NEWEBSEmergent BioSolutions$24,300$24,300 ▲New Holding5,0000.0%MedicalADMAADMA Biologics$24,300$12,931 ▼-34.7%810,0000.0%MedicalNKTXNkarta$18,400$18,400 ▲New Holding10,0000.0%MedicalAPREAprea Therapeutics$14,400$6,617 ▼-31.5%102,2420.0%MedicalESPREsperion Therapeutics$14,400$14,400 ▲New Holding10,0000.0%MedicalIRWDIronwood Pharmaceuticals$0$2,874,118 ▼-100.0%00.0%MedicalJAZZJazz Pharmaceuticals$0$1,231,500 ▼-100.0%00.0%MedicalTSVT2seventy bio$0$882,000 ▼-100.0%00.0%MedicalANTX(ANTX)$0$271,490 ▼-100.0%00.0%MedicalELEVElevation Oncology$0$112,520 ▼-100.0%00.0%MedicalABIVAX SA$0$109,800 ▼-100.0%00.0%SPONSORED ADSALIMERA SCIENCES INC CVR$0$107,124 ▼-100.0%00.0%COMALLARITY THERAPEUTICS INC$0$78,728 ▼-100.0%00.0%COMRVNCRevance Therapeutics$0$70,723 ▼-100.0%00.0%MedicalShowing largest 100 holdings. 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