Immunic (NASDAQ:IMUX) is a clinical-stage biopharmaceutical company focused on developing novel oral therapies to treat chronic inflammatory and autoimmune diseases as well as certain cancers. The company’s research strategy centers on small-molecule immunology, aiming to offer targeted treatments with improved safety and tolerability profiles. By modulating key signaling pathways within the immune system, Immunic seeks to address underlying disease mechanisms and achieve durable therapeutic benefits for patients.
Immunic’s lead product candidate, vidofludimus calcium (IMU-838), is an oral selective dihydroorotate dehydrogenase (DHODH) inhibitor in Phase 2 clinical development for conditions including ulcerative colitis, Crohn’s disease and relapsing multiple sclerosis. A second program, IMU-935, targets the RORγt pathway, with preclinical and early-stage clinical studies designed to assess its potential in treating psoriasis and other inflammatory disorders. Both programs reflect the company’s commitment to advancing therapies that may offer improved efficacy and convenience compared to existing injections or infusions.
Founded in 2008 and headquartered in New York, Immunic maintains research operations in Germany to leverage its European expertise in medicinal chemistry and translational science. This transatlantic footprint supports robust clinical trial activity and enables collaboration with international academic and clinical partners. Over the years, the company has progressed its pipeline through strategic financing rounds and regulatory engagement, culminating in its NASDAQ listing in early 2020.
Under the leadership of Chief Executive Officer Friederike Bertram, M.D., Immunic continues to expand its pipeline and explore additional indications for its platform of oral immunology agents. Guided by a management team experienced in drug development and regulatory affairs, the company aims to bring new therapeutic options to patients living with immune-mediated diseases and certain oncologic conditions.
