NASDAQ:SYRE Spyre Therapeutics Q1 2025 Earnings Report $84.72 -1.07 (-1.25%) Closing price 09/29/2026 04:00 PM EasternExtended Trading$88.25 +3.53 (+4.17%) As of 08:43 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. ProfileEarnings HistoryForecast Spyre Therapeutics EPS ResultsActual EPS-$0.74Consensus EPS -$0.76Beat/MissBeat by +$0.02One Year Ago EPSN/ASpyre Therapeutics Revenue ResultsActual RevenueN/AExpected RevenueN/ABeat/MissN/AYoY Revenue GrowthN/ASpyre Therapeutics Announcement DetailsQuarterQ1 2025Date5/8/2025TimeBefore Market OpensConference Call DateThursday, May 8, 2025Conference Call Time4:00PM ETUpcoming EarningsSpyre Therapeutics' Q3 2026 earnings is estimated for Tuesday, November 3, 2026, based on past reporting schedules, with a conference call scheduled on Friday, November 6, 2026 at 4:00 PM ET. Check back for transcripts, audio, and key financial metrics as they become available.Conference Call ResourcesPress Release (8-K)Quarterly Report (10-Q)Earnings HistoryCompany ProfilePowered by Earnings DocumentsPress Release(8-K)Quarterly report(10-Q) Spyre Therapeutics Earnings HeadlinesSpyre Therapeutics, Inc. (SYRE)September 29 at 7:40 AM | finance.yahoo.comAnalyzing Surrozen (NASDAQ:SRZN) & Spyre Therapeutics (NASDAQ:SYRE)September 24, 2026 | americanbankingnews.comA letter from Shannon StansberryPorter Stansberry nearly canceled the entire project. When he first saw the claimed returns - only one down year in nearly two decades and total gains of almost 2,000% - his immediate reaction was disbelief. It took a trusted friend's personal vouching for Emmet Savage and a face-to-face trip to Ireland to change his mind. The full documentary, Investigating Project Prophet, is now live.September 30 at 1:00 AM | Porter & Company (Ad)Spyre Therapeutics, Inc. (NASDAQ:SYRE) Given Consensus Rating of "Moderate Buy" by BrokeragesSeptember 20, 2026 | americanbankingnews.comSpyre (SYRE) Clears Monotherapy Phase for IBD Portfolio, Setting Up Combination TestsSeptember 17, 2026 | finance.yahoo.comSpyre Therapeutics (SYRE) Reports SPY003 Endoscopic Improvement. Can Randomized Testing Confirm It?September 10, 2026 | insidermonkey.comSee More Spyre Therapeutics Headlines Get Earnings Announcements in your inboxWant to stay updated on the latest earnings announcements and upcoming reports for companies like Spyre Therapeutics? Sign up for Earnings360's daily newsletter to receive timely earnings updates on Spyre Therapeutics and other key companies, straight to your email. Email Address About Spyre TherapeuticsSpyre Therapeutics (NASDAQ:SYRE) is a clinical-stage biotechnology company focused on developing antibody therapeutics for inflammatory bowel disease (IBD), including ulcerative colitis and Crohn’s disease. The company is working to create next-generation biologic medicines intended to address significant treatment needs in these chronic gastrointestinal conditions. Spyre’s pipeline includes programs directed at validated inflammatory pathways, including interleukin-23 (IL-23) and tumor necrosis factor-like ligand 1A (TL1A). Its research approach emphasizes antibody engineering, with the goal of developing therapies that may offer durable activity, convenient dosing, and potential use in combination treatment regimens. The company’s programs remain in clinical development and are subject to ongoing evaluation for safety and effectiveness. The company was formed through a transaction involving Aeglea BioTherapeutics and Spyre Therapeutics and began trading under the name Spyre Therapeutics and the Nasdaq symbol SYRE in 2023. Spyre is headquartered in the United States and conducts its drug discovery and development activities through research, clinical, and corporate operations. Its leadership includes Chief Executive Officer and President Cameron Turtle, Ph.D.View Spyre Therapeutics ProfileRead more More Earnings Resources from MarketBeat Earnings Tools Today's Earnings Tomorrow's Earnings Next Week's Earnings Upcoming Earnings Calls Earnings Newsletter Earnings Call Transcripts Earnings Beats & Misses Corporate Guidance Earnings Screener Latest Articles CarMax Just Gave Investors a Better Reason to Believe in the TurnaroundBernstein Downgrades 3 Cybersecurity Stocks: How Concerned Should Investors Be?Brewing Trouble? 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