Inspire Medical Systems Q2 2025 Earnings Report

Inspire Medical Systems EPS Results

• Actual EPS: $0.45
• Consensus EPS: $0.22
• Beat/Miss: Beat by +$0.23
• One Year Ago EPS: $0.32

Inspire Medical Systems Revenue Results

• Actual Revenue: $217.09 million
• Expected Revenue: $214.50 million
• Beat/Miss: Beat by +$2.59 million
• YoY Revenue Growth: +10.80%

Inspire Medical Systems Announcement Details

• Quarter: Q2 2025
• Date: 8/4/2025
• Time: After Market Closes
• Conference Call Date: Monday, August 4, 2025
• Conference Call Time: 5:00PM ET

Inspire Medical Systems (NYSE:INSP), a medical technology company, focuses on the development and commercialization of minimally invasive solutions for patients with obstructive sleep apnea (OSA) in the United States and internationally. The company offers Inspire system, a neurostimulation technology that provides a safe and effective treatment for moderate to severe OSA. It also develops a novel, closed-loop solution that continuously monitors a patient's breathing and delivers mild hypoglossal nerve stimulation to maintain an open airway. The company was incorporated in 2007 and is headquartered in Golden Valley, Minnesota.

Inspire Medical Systems Q2 2025 Earnings Call Transcript

Key Takeaways

• Negative Sentiment: 2025 guidance lowered as revenue outlook was cut to $900–910 million (down from $940–955 million) and EPS guidance trimmed to $0.40–0.50 (from $2.20–2.30) due to transition headwinds and increased marketing spend.
• Neutral Sentiment: Inspire five rollout challenges included delayed SleepSync IT approvals and postponed Medicare billing, though over 50% of US centers now have SleepSync and full implementation is expected by end of Q3.
• Positive Sentiment: Early clinical data for Inspire five show a 20% reduction in surgical time and US centers that transitioned saw a 20%+ increase in implant volume, plus 86% inspiratory overlap accuracy.
• Positive Sentiment: Proposed 2026 reimbursement uplift for CPT code 64568 would boost Medicare hospital rates by 4%, ASC rates by 5%, and surgeon fees by 11%, enhancing device margins.
• Neutral Sentiment: Patient marketing ramp-up and footprint expansion accelerate in H2 with over 20% growth in DTC spend and expanded digital scheduling to drive awareness and capacity.

Presentation

[Operator]

Good afternoon. My name is Dilem, and I'll be your conference operator today. At this time, I would like to welcome everyone to the Inspire Medical Systems Second Quarter twenty twenty five Conference Call. All lines have been placed on mute to prevent any background noise. After the speakers' remarks, there will be a question and answer session.

[Operator]

I'll now hand the call over to your first speaker, Eske Yaja, the Vice President of Investor Relations at Inspire. You may begin the conference.

[Ezgi Yagci, VP - IR at Inspire Medical Systems]

Thank you, Delheim, and thank you all for participating in today's call. Joining me are Tim Herbert, Chairman and Chief Executive Officer and Rick Beevolz, Chief Financial Officer. Earlier today, we released financial results for the three months ended 06/30/2025. A copy of the press release is available on our website. On this call, management will make forward looking statements within the meaning of the federal securities laws.

[Ezgi Yagci, VP - IR at Inspire Medical Systems]

All forward looking statements, without limitation, those relating to our operations, financial results and financial condition, investments in our business, full year 2025 financial and operational outlook, and changes in market access are based upon our current estimates and various assumptions. These statements involve material risks and uncertainties that could cause actual results or events to materially differ. Accordingly, you should not place undue reliance on these statements. Please see our filings with the Securities and Exchange Commission, including our Form 10 Q, which we filed with the SEC earlier this afternoon, for a description of these risks and uncertainties. Inspire disclaims any intention or obligation, except as required by law, to update or revise any financial projections or forward looking statements, whether because of new information, future events, otherwise.

[Ezgi Yagci, VP - IR at Inspire Medical Systems]

This conference call contains time sensitive information and speaks only as of the live broadcast today, 08/04/2025. With that, it is my pleasure to turn the call over to Tim Herbert. Tim?

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Thank you, Resge, and thanks, everyone, for joining our business update call for the 2025. I'll start by highlighting some key takeaways of our second quarter results. I'll then discuss our updated 2025 guidance and provide additional context and rationale around the change. Then Rick will provide a financial review. We will then open the call for questions.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

It has been an impressive start to the year 2025 and we have achieved many key milestones. That said, I want to provide some important context on the challenges we are facing in the commercial rollout of our Inspire five next generation system, which began in May. As the quarter progressed, we encountered certain headwinds that slowed our efforts to transition customers to Inspire five. While we are disappointed with the elongated timeframe we now expect for the rollout, we remain focused on advancing the transition of our customers to Inspire five. To this end, we are taking concrete actions that we believe will allow us to complete this transaction in the next few quarters.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Strong market demand, positive patient and surgeon feedback, and favorable clinical results give us conviction in our platform and ability to make a difference in the lives of our patients with obstructive sleep apnea. I'd now like to provide some detail regarding the challenges faced during the quarter and the steps we're taking to actively address the factors at play. First, in the second quarter, many centers did not complete the training, contracting, and onboarding criteria required prior to the purchase and implant of INSPIRE five. Specifically, implementation of sleep sync has been the most challenging step to accomplish. Although not technically difficult, the approval process from our customers' IT departments has taken longer than expected.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Additionally, some centers have been delaying implementing SleepSync until their first patients are scheduled to receive the Inspire five device. To increase the rate of implementation of SleepSync by our customers, we began and continued to leverage our technical teams. To date, we have completed the implementation at over 50% of The U. S. Centers.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

With these technical resources fully engaged, we expect to complete the vast majority by the end of the third quarter. As an aside, most of the units sold in the second quarter were Inspire 4s. Therefore, we did not experience much inventory destocking in the second quarter. The burn down of Inspire four inventory will remain a headwind in the 2025 as we continue the transition to INSPIRE V. The second challenge related to adoption of CPT code 64568 for INSPIRE V for Medicare patients.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

The approval of the code change was announced in April with a retroactive effective date of 01/01/2025. However, the software updates for claims submissions and processing did not take effect until July 1. Thus, although traditional Medicare and Medicare Advantage patients could receive Inspire therapy, implanting centers would not be able to bill for those procedures until July 1. Given this dynamic, many centers continued to treat Medicare patients with Inspire four. With this software update now complete, we anticipate centers will ramp up their efforts to transition to Inspire five.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Third, certain patients opted to wait for the Inspire five device knowing its availability was imminent instead of being treated with Inspire four. And as more centers transitioned to Inspire five into the third quarter, these patients should start receiving Inspire five therapy. Fourth, we intentionally held off on patient marketing and education spend and footprint expansion, namely new centers and territories, in the first half of the year. This was a strategic decision given all the resources required for the Inspire five transition. As we move into the second half of the year, we have ramped up both marketing and footprint expansion efforts to increase patient awareness and build capacity across The U.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

S. These investments have already started to be implemented and we have already experienced an increase in website activity, calls into our advisor care program, and appointments to health care providers. We continue to leverage our ACP to connect patients interested in Inspire therapy with qualified physicians, including through the expansion of digital scheduling. In addition, we are ramping our medical education and local community health talk efforts to promote the launch of Inspire five. These efforts should provide a tailwind into the 2025 and beyond.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Lastly, we believe some patients may be delaying Inspire therapy to try GLP-one. We are unable to quantify this and continue to believe GLP-1s present a tailwind long term as we do hear of patients losing weight to qualify and receive Inspire therapy. As an example, when a prospective patient fails the DICE procedure due to complete concentric collapse, our centers work with the patients to help address their high BMI, including prescribing a GLP-one. As a result of these headwinds, we are adjusting our full year revenue guidance to a range of 900,000,000 to $910,000,000 from our previous revenue guidance of $940,000,000 to $955,000,000 or a 4% reduction at the midpoint. The new revenue guidance reflects growth of 12% to 13% over 2024 revenue.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

We are also reducing our diluted net income per share to a range of $0.04 0 to $0.50 from our previous guidance of $2.2 to $2.3 per share to reflect this change in revenue guidance and to a lesser extent, the planned increase in patient marketing cost for the second half of the year. I will now take a few minutes to highlight the success we have already seen with the INSPIRE-five system and what to expect moving forward. The early results of our Singapore clinical study have been presented at the recent sleep meeting and demonstrated a twenty percent reduction in surgical times. This reduction will provide for increased capacity at centers. In fact, we have already noted that The US centers that have completed the transition to INSPIRE V have experienced a more than twenty percent increase in patient implants in the 2025 as compared to the same period in 2024.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

From an efficacy standpoint, the accelerometer study we highlighted at recent investor conferences suggested significantly improved sensing capability, including an 86% inspiratory overlap with a patient's breathing. Synchronization with respiration is essential as the airway collapses during the inspiratory phase of respiration. The early review of AHI reductions appears very promising as well. And we plan to present this data at the upcoming ENT meetings in October. Regarding reimbursement, CMS recently released the twenty twenty six proposed OPPS rules, which, if approved, would provide positive increases for Medicare reimbursement for the Inspire system.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

As you know, for Inspire V, centers will be billing CPT code 64568, which has been accepted for plans covering over 90% of our 300,000,000 covered lives, including Medicare. The national average Medicare hospital reimbursement for CPT code 64568 is proposed to increase to $32,000 up roughly $1,300 or 4% from 2024. And the ASC reimbursement is proposed to increase to $28,000 up $1,300 or 5% compared to 2024. Finally, the surgeon reimbursement for CPT code 64568 is projected to increase to $660 up 11% as compared to 2024. Should the proposed rules be finalized as expected early November, the new reimbursement would take effect 01/01/2026.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

With respect to clinical evidence, we are very excited to have submitted the predictor manuscript to a leading journal and expect it to be published later this year. As a reminder, the clinical evidence proposes an algorithm which uses BMI and neck circumference to determine a patient's eligibility, thereby eliminating the need for a DICE procedure for the vast majority of patients. We're also excited to announce that we became a corporate champion of the American Academy of Otolaryngology. The sponsorship positions Inspire is the leading voice in ENT innovation, aligning with top thought leaders and decision makers. It also strengthens our brand and trust within the ENT community, which is vital for expanding Inspire's influence and adoption.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

It also provides a platform for collaboration and research and policy, thereby advancing Inspire's market leadership in hyperglottal nerve stimulation. Before I turn the call over to Rick, I'd like to take a moment and discuss a personnel announcement we made today. No one has lived up to our commitment to delivering strong patient outcomes more than Randy Bann, our Executive Vice President, Patient Access and Therapy Awareness. Randy recently announced his intention to retire at the January 2026. As one of our earliest team members and a longtime commercial leader at Inspire, Randy has played a significant role in advancing access to Inspire therapy and building a strong mission driven organization.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

He will remain fully engaged in his current role into early next year to support a smooth and thoughtful transition. We are grateful to Randy for his many contributions and wish him the best in his well earned retirement. At the beginning of this year, Carlton Wetherbee assumed the lead of the U. S. Sales and marketing teams and will continue to build upon the robust history of growth in the adoption of Inspire therapy initiated by Randy many years ago.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

In summary, we remain focused on the patient to continue the growth and adoption of Inspire therapy. We will execute our growth strategy of driving high quality patient flow and increasing the capacity of our provider partners to effectively treat and manage more patients. Our key strategies include training advanced practice providers, certifying additional surgeons qualified to implant flare therapy, and driving the adoption of SleepSync and our digital tools, all of which are embedded strategies and our commercial team's objective to increase provider capacity. Looking ahead, we are confident about our future and that we have the appropriate strategy in place to drive long term stakeholder value. We have our arms around the headwinds that I described and actions are already underway to accelerate the adoption of Inspire five in the latter half of the year.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Looking beyond 2025, we continue to take actions to position the company for strong, profitable growth. With that, I'd like to turn the call over to Rick for his review of our financials.

[Rick Buchholz, Chief Financial Officer at Inspire Medical Systems]

Thank you, Tim, and good afternoon, everyone. Total revenue for the quarter was $217,100,000 an 11% increase from the $195,900,000 generated in the 2024. US revenue in the quarter was $207,200,000 an increase of 10% from the $187,800,000 in the prior year period. Revenue outside The US was $9,900,000 which was a 23% increase year over year. Gross margin in the quarter was 84% compared to 84.8% in the prior year period.

[Rick Buchholz, Chief Financial Officer at Inspire Medical Systems]

The year over year decrease was primarily due to a 2,100,000.0 charge for excess INSPIRE IV subcomponents, which reduced gross margin by 100 basis points in the quarter. Total operating expenses for the quarter were $185,700,000 an increase of 15% as compared to $160,900,000 in the 2024. This increase was primarily due to the expansion of our sales organization and increased general corporate costs, partially offset by a reduction in R and D year over year. In addition, operating expenses included accelerated non cash stock based compensation expense of $11,200,000 for employees who are now retirement eligible in accordance with the implementation of changes to the treatment of equity awards upon an employee's death, disability or retirement. Operating expenses also included $1,700,000 in legal fees related to a civil investigative demand from the Department of Justice and a patent infringement suit that we filed against a potential competitor.

[Rick Buchholz, Chief Financial Officer at Inspire Medical Systems]

These items do not reflect costs associated with our ongoing operations. Please refer to our earnings press release for a reconciliation of these items. Interest and dividend income totaled $4,500,000 in the quarter compared to $5,900,000 in the prior year period. Operating loss for the quarter totaled $3,300,000 compared to an operating income of $5,100,000 in the prior year period. Net loss for the quarter was $3,600,000 compared to a net income of $9,800,000 in the prior year period.

[Rick Buchholz, Chief Financial Officer at Inspire Medical Systems]

This represented a loss per share of $0.12 for the quarter compared to a net income of $0.32 per share in the 2024. Adjusted EBITDA for the quarter totaled $44,100,000 which is a 14% increase compared to $38,700,000 in the prior year period. The adjusted EBITDA margin in the second quarter was 20% and consistent with the 2024. Adjusted net income per share totaled $0.45 compared to $0.32 in the prior year period, or an increase of 40% year over year. The weighted average number of diluted shares outstanding for the quarter was 29,500,000.

[Rick Buchholz, Chief Financial Officer at Inspire Medical Systems]

We ended the quarter with $411,000,000 in cash and investments. Our strong cash position allows us to remain focused on executing our growth strategies. Moving on to 2025 guidance. As Tim mentioned, we now expect full year revenue to be in the range of 900,000,000 to $910,000,000 down from $940,000,000 to $955,000,000 representing an annual increase of 12% to 13% compared to full year 2024 revenue. We expect Q3 revenue to increase 1% to 3% sequentially from the second quarter as we continue the transition to Inspire V.

[Rick Buchholz, Chief Financial Officer at Inspire Medical Systems]

We continue to expect full year gross margin to be in the range of 84% to 86%. We now expect diluted net income for the full year 2025 will be $0.40 to $0.50 per share, a decrease from our previous range of $2.2 to $2.3 dollars per share. The reduction is primarily due to the revised revenue guidance and, to a lesser extent, the planned increase in patient marketing costs for the second half of the year. We ended the quarter with three forty eight US territories and two fifty nine US field clinical representatives. We continue to expect our reported tax rate in 2025 to be roughly 10%, primarily related to state and local taxes.

[Rick Buchholz, Chief Financial Officer at Inspire Medical Systems]

We expect the full year diluted shares outstanding to be approximately $31,000,000 With that, our prepared remarks are concluded. Dulham, you may now open the line for questions.

[Operator]

Thank you. We ask that you please keep your questions to no more than one question and one follow-up. And if time permits, we'll be more than happy to take more questions. Please stand by while we compile the Q and A roster. And I show our first question comes from the line of Adam Mader from Piper Sandler. Please go ahead.

[Adam Maeder, MD & Senior Research Analyst at Piper Sandler Companies]

Hi, good afternoon. Thank you for taking the questions. A couple from me, I guess, the first one is on the revised guidance. And you guys outlined a handful of different headwinds that are facing the business here. Was just hoping to get a little bit more color there, if you could kind of put some force rank order around those different items or quantification around those items so we can kind of understand those different components and kind of how you're thinking about the potential impact in the second half of the year. Then I have a follow-up. Thanks.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Sounds great, Adam. How are you doing? Good to hear from you. I think when we laid out the four key items that we highlighted, the first two are really the predominant factors that we had. And the first one certainly being the number of centers that have completed their full training and adding SleepSync to their systems to be able to use the Inspire five programmer.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

And the second is really the concern over billing Medicare, which is everybody was aware of it being approved, but not being able to bill it until July 1 has really put some centers in a a tough spot, and so they chose to continue to implant INSPIRE IV. Those two factors really are the predominant drivers, and we really got our arms around both of those. Of course, the Medicare is now approved and centers are able to bill 64,568 for INSPIRE V, and we have a full team working to get all the other centers trained and up and running. As we mentioned, over 50% of the centers have already have access to sleep sick.

[Adam Maeder, MD & Senior Research Analyst at Piper Sandler Companies]

That's helpful color, Tim. Thank you for all that. And for the follow-up, I'm gonna test my luck 2026 and the rollout obviously going slower than expected with Gen five here this year. But you gave some kind of helpful color around kind of how you're thinking about the trajectory in the back half of the year. Maybe to ask it a little bit more directly, would you expect revenue in 2026 to accelerate over the 12% to 13% that you've guided to in FY 2025? Thanks so

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Absolutely.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

We're going to provide our next year's guidance, of course, at a year end call. But we're making several investments, as I've already mentioned, to get the sites up and running with Inspire five. We talked about the increased marketing with our direct to consumer spend, expanding our footprint, both with new centers, with surgeons, bringing back some of the surgeons who weren't doing as many procedures because of the pressure sensing lead before. And so yes, we would expect our revenue growth to exceed the 12 to 13 we're talking about now.

[Adam Maeder, MD & Senior Research Analyst at Piper Sandler Companies]

Thanks very much.

[Operator]

Thank you. And I show our next question comes from the line of Travis Steed from Bank of America Securities. Please go ahead.

[Travis Steed, MD - Equity Research at Bank of America]

Hey, thanks for taking the question. I wanted to ask about the EPS guide change. I know the numbers in the press release, the 2.2 to $2.3 went to $0.04 0 to $0.50 There was, I guess, a $0.57 onetime charge this quarter. But trying to get the bridge kind of back to the underlying EPS guide kind of on an adjusted basis, if you could kind of help walk how the guide changed versus the 2.2 to $2.3 that you gave last quarter.

[Rick Buchholz, Chief Financial Officer at Inspire Medical Systems]

Sure. Hey, Travis. So the most significant item there is just the gross margin that we're going to the reduced gross margin that we would obtain had we had higher revenue. So really, the biggest impact there is the reduction of the revenue guide from our previous midpoint of $948,000,000 down to $9.00 $5,000,000 So that's the majority of that. But we are also increasing our DTC spend too.

[Rick Buchholz, Chief Financial Officer at Inspire Medical Systems]

So to a lesser extent, there's some impact there from continued investments. And the big driver there is that we expect to actually increase our DTC investments significantly now that we've got the launch underway. And so part of that launch is we want to take advantage of the launch with INSPIRE V to ensure that we're building patient awareness. And so that growth we had DTC at 95,000,000 in 2024, expect that to be over 20% growth, which implies about 115,000,000 in 2025.

[Travis Steed, MD - Equity Research at Bank of America]

So the $0.04 0 to $0.50 EPS guide is excluding the $0.57 one time charge this quarter, just to be clear?

[Rick Buchholz, Chief Financial Officer at Inspire Medical Systems]

No. That's included. It's it's GAAP EPS. It's inclusive of that.

[Travis Steed, MD - Equity Research at Bank of America]

Okay. So if I take the $2.28 versus $2.3 subtract the $0.57 and that should be under the underlying EPS guide, right?

[Rick Buchholz, Chief Financial Officer at Inspire Medical Systems]

Yes, because you have original The underlying guide is a midpoint of $0.45 roughly $1.0.2 for the reduction in revenue, and then roughly $0.60 for the one time items. Yes, correct.

[Travis Steed, MD - Equity Research at Bank of America]

Okay. Just want to make sure that was clear since it's confusing for a lot of people. And then the second question I had was just on the Q3 guide and any kind of view on June, July trends that kind of helped inform that Q3 guide up 1% to 3% sequentially? Thank you.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Hi, Travis. No, I think as we come out, it's always a little bit lower at the beginning of a quarter, especially when you're talking about the July. But we do see the patient flow that we're working through in the second quarter and be able to get a handle on where we are from patient flow and expected implants to be able to guide a 1% to 3% step up over the second quarter revenue. So those are just the early views that we see from the patient flow.

[Travis Steed, MD - Equity Research at Bank of America]

Okay. Thanks a lot.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Thank you, Travis.

[Operator]

Thank you. And I show our next question comes from the line of Danielle Antalffy from UBS. Please go ahead.

[Danielle Antalffy, Analyst at UBS Group]

Hey, good afternoon, guys. Thanks so much for taking the question. Just want to make sure I understand what's happening here on underlying volume trends. Appreciate all the color you provided, Tim. But I guess even if it's a matter of, like, slower transition to inspire five volumes seem to be lower than than what well, certainly than what you guys have been tracking over the last few years, but, you know, than what a lot of people expected.

[Danielle Antalffy, Analyst at UBS Group]

And so I guess some of that is, you know, patients choosing to to wait. But I guess I'm just curious, like, why you're still seeing such pressure on on volumes. And I I know it's hard to quantify, like, the GLP one impact, things like that. But anything you can say there to just give us, some more confidence that this is truly temporary and not something structural the market would be great. Sorry, I know that's an open ended question, and I'll just leave it at that.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Thanks, Danielle. I think, well, first off, in the second quarter, we did achieve expectations with our revenue in taking care of patients. So we did have a good patient flow there to achieve what we set expectations or set guide to be in the second quarter. But as we look forward, knowing the delay in getting all the centers up and running, that pushes our cases forward. And it also limited our ability to increase the footprint.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

So we didn't add as many centers in the second quarter as we're working on the transition. We didn't add as many territory managers as we noted in the script. We did increase the number of field clinical reps because that builds the capability to move forward. And again, as Adam asked earlier on, the two key factors of getting the sites up and running to transition to five and really the ability to build Medicare. Centers really had a difficult time billing Medicare knowing that they wouldn't get billing accepted until July 1.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

The other two factors do play as well, of course, with the patients who are expecting or waiting for Inspire five, but until their centers are up and running, they certainly can't get in the queue to be able to get scheduled for that, but we know those patients are there. And then finally, with the majority of the units being sold in the quarter being Inspire 4s, we still have a burn down of inventory that will carry forward moving forward. So yes, we have strong confidence in our ability to move forward and that's really highlighted by the great performance that we're seeing with Inspire V device so far, both in The US and again, as we mentioned, from the clinical study in Singapore. And we're going to be proud to present some more of those results at the upcoming ENT meeting. So yeah, the team's got their head down, they're working hard.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

We think we got our arms around the headwinds limiting the Inspire five transition and have good confidence that we have the corrective actions in place to be able to overcome those.

[Danielle Antalffy, Analyst at UBS Group]

Okay. Thanks for the comprehensive answer.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Thanks, Danielle.

[Operator]

Thank you. And I show our next question comes from the line of Robbie Marcus from JPMorgan. Please go ahead.

[Robert Marcus, Senior Analyst at JPMorgan Chase]

Great. Thanks for taking the questions. Two for me. First one, Tim, I appreciate you're not commenting on 2026. But would the expectation be, given this is a transient issue, that you'd basically go back to your prior run rate in 2026, meaning you'd get back the 40,000,000 to $45,000,000 in revenue cut that you had here in 'twenty five next year if it's not demand related?

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

I think that that's what we're going be targeting for. I think that we do think this is a short term issue. And with the shift, it limits our ability to work through Q3 and Q4, but it does set us up for a very promising 2026 and beyond as we need to be focused to get all the sites transitioned over. But we already have the payers in place, as we mentioned, the CPT coding. We have Medicare now in place and we have seen positive experience from centers that have already implemented INSPIRE V.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

So again, we're going to give the formal guidance when we move forward, but our intent is to bring the growth back absolutely.

[Robert Marcus, Senior Analyst at JPMorgan Chase]

Great. Maybe just a follow-up. You've had approval for a long while now. You were in limited launch for many months. The launch isn't going according to plan.

[Robert Marcus, Senior Analyst at JPMorgan Chase]

What would you say if you compare now versus on the first quarter call, which was partway into the second quarter? What exactly didn't go to plan? What was the biggest delta versus expectations?

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Sure.

[Robert Marcus, Senior Analyst at JPMorgan Chase]

How do you plan to fix those shortcomings through

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

I the rest of the this is the largest launch in the history of the company. There's no question about it. It's one of the largest launches in med tech based on where we are today. So there are challenges that go with it. At the beginning of the year, really we're focused more on making sure we have sufficient inventory to be able to even start the launch.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

And so we're really limiting the number of centers that could be exposed to INSPIRE-five, being able to pick up enough data to have confidence moving forward in the rollout. As we got to May when we did the full launch and started to roll it out, we did have the opportunity with the extended time to be able to get all the reimbursement in place and we did have Medicare approved, although when they do their documentation they do it twice a year. And of course, we weren't part of the January release knowing we had to wait until the July release had one issue. So that's a timing factor. But then the sleep sync is really the big change too because that gives us the advantage to be able to capture the information when physicians do the device programming.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

So that's really a long term opportunity to build the robustness of the Inspire system. And so it is a complex launch, but I think now we have our arms around it. I think having inventory earlier would have allowed us to release this earlier, albeit we still would have been constrained from a Medicare standpoint. But yeah, we do take it to heart and do look closely at a lot of the details and when we go into our programs moving forward on what can we do to enhance that going forward and have some better planning to address some of the challenges that we've seen.

[Robert Marcus, Senior Analyst at JPMorgan Chase]

Appreciate it. Thanks, Tim.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Thanks, Robbie.

[Operator]

Thank you. And I show our next question comes from the line of Richard Newitter from Truist Securities. Please go ahead.

[Richard Newitter, Managing Director at Truist Securities]

Hi, thanks for taking the questions. Just a couple here and I'll list them all upfront. I'm curious if you could just parse out a little bit more clearly for us. Is this entirely Inspire five execution related and that's the transient item that gives you confidence here for moving into 2026. You did call out GLP-one impact a little bit more concretely than you have in the past. So I'm just trying to understand between that and maybe capacity utilization, what's potentially nearer term transient and then what's related to those other items? And anything you can give us on kind of underlying demand trends since there is inventory in the channel?

[Richard Newitter, Managing Director at Truist Securities]

And then sorry, two more. Your accounts receivable stepped up. I just wanted to know kind of how that factors into some of these considerations. And then lastly, you talked about a 20% increase for Inspire five users that have adopted in the first half. I'm just curious what's driving that?

[Richard Newitter, Managing Director at Truist Securities]

Is that patients that just aren't able to get INSPIRE five, but they found the few physicians who have them going there? Or is it actually throughput increases and physicians doing more procedures on their planned INSPIRE days? Thank you.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

You bet, Rich. Got it. Okay. Start with number one, Inspire five transition. And is that really the overriding element that's limiting patient flow?

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Again, I think we had good patient flow in the second quarter and we achieved the expectations that we set forward, but it was the continuation of the patient flow going into the third quarter. While the Inspire five is the leading issue there, there are underlying elements to it. Well, obviously the four items I talked about with the Inspire four, specifically sites being ready to go with five, the Medicare, some patients waiting for the Inspire five, and of course, the burn down of inventory. We also held back, remember, a little bit on our DTC and a little bit on our footprint expansion. So not purposely going out and adding a lot of reps, making sure that the team stays in place, focused with existing centers, get them transitioned to five and then turn around and really start to expand that.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

And that specifically is what we've started here in the third quarter, not just increased DTC, but an increased focus on building the footprint in The United States. And then we'll come back to, that's going to grow, capacity. No question about it. GLP-one impact, we're going to keep watching that closely. We do think that as the indication has come out, we may see pockets of that, with some of our centers of patients wanting to trial GLP-one and we've talked about that with you before.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

But again, we do think that's a real tailwind into the future. It's really about helping patients lose weight, addressing their lateral wall collapse. So we don't think that's a significant impact, but we're watching that very, very closely. I'm going to skip by accounts receivable and give that to Rick and go down to the third question, which is the 20% improvement in patient flow with implants with our physicians. These are with our limited release sites.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

And this is patient implant, this is patient flow, those are real numbers. We're tracking their implants during the '25 versus the '24. And these aren't new centers in '24, these are centers that had full year '24 as well. So it's a true apples to apples. And it's a reduction in the surgical complexity of five that allows them to improve their capacity.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

But more importantly, Rich, it's about them not having to put in the pressure sensing lead because as we remember, that sensing lead into the thoracic, not into the thoracic cavity, into the intercostal muscles is part of the surgery that is just not the most comfortable part for ENTs. And that really has been the number one primary positive feedback. So that being said, I'm going to back up to number two and ask Rick to comment on accounts receivable.

[Rick Buchholz, Chief Financial Officer at Inspire Medical Systems]

Yeah, Rich. The accounts receivable increase is really a twofold item. The primary driver there is in May, we actually completed a transition to a new customer billing service that helps automate and streamline our billing process, which is an upgrade from our previous manual billing process. And with that implementation of the new system, we had a temporary delay in the delivery of customer invoices actually with the new portal and our new automated delivery process. That temporary delay has been resolved, we expect to have this fully remediated in the third quarter.

[Rick Buchholz, Chief Financial Officer at Inspire Medical Systems]

So it's really just a timing. We'll get those collections here as we get into the third quarter. And then to a much lesser extent too is the second quarter was a little back end loaded in the fact that we had a really strong June. And so that also contributed to the increase in accounts receivable balance at the end of the quarter.

[Operator]

Thank you. And I show our next question in the queue comes from the line of David Prescott from Baird. Please go ahead.

[David Rescott, Senior Research Analyst at Baird]

Great. Thanks for taking the questions. Ricky, you answered the question earlier, but I wanted to just make crystal clear the updated EPS guide for the year, the $0.40 to $0.50 that's now in the guide relative to the prior $2 plus guide. Is that $0.40 to $0.50 relative to the negative $02 of net income per share or relative to the $0.55 of adjusted net income per share you've delivered year to date so far? And I guess based on that answer, are you expecting incremental stock based comp for this retirement component in the back half of the year as well? And then I have a follow-up.

[Rick Buchholz, Chief Financial Officer at Inspire Medical Systems]

Yeah. To your first question, it's relative to the $02 earnings per share to address your first question. And then the implementation of the retirement policy was really a one time charge, and we expect our stock based compensation to revert back to traditional levels as a percentage of our revenue going forward.

[David Rescott, Senior Research Analyst at Baird]

Okay, that's helpful. Then, Tim, you called out the three or four or five components of this lowered outlook for the year. And I'm curious on if you can bucket it in so much as to the progress that those have recovered either in June, in the back half of the quarter or already in July. Just based on kind of some of the trends you're seeing in the back half, where we kind of stand from a, hey, are some of these headwinds bottoming out? Are they on the up at this point? Any color there would be helpful. Thank you.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Absolutely, David. So the first two, the primary contributors, as we mentioned, the first one being the centers being up and running. Remember, we had to do the training, contracting and implementation of SleepSync. And we mentioned SleepSync is already adopted in 50% of the centers. Training is already complete because the training of surgeons is relatively straightforward, right?

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Don't implant the pressure sensing lead anymore and it's a little bit more streamlined. And contracting is even above that of implementation of sleep sync. So we've really got our arms around those three elements of getting centers up and running. So I think we're in a good position there with a strong focus from the team. Number two, of course, is Medicare and that is complete, right?

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

We do have the new code 64568 approved by Medicare. The documentation is complete. The software is updated and Medicare is accepting billing for Inspire procedures to that new code today. So that one is complete. The rest of them will keep coming as we keep expanding.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

And then beyond that, we are working diligently to increase the footprint agenda, add additional centers, to train additional centers, and maybe those physicians who weren't as excited about implanting the pressure sensing lead, that creates an opportunity for us and the team is really leaning in on that. So again, we think we have our arms around that as well and look forward to continue to report back on that.

[Operator]

Thank you. And I show our next question comes from the line of Michael Cercone from Jefferies. Please go ahead.

[Michael Sarcone, Analyst at Jefferies]

Good afternoon and thanks for taking the question. I guess just first, Tim, to follow-up on the Medicare billing and software update. You said that's been available since July 1. Could you give us any sense of what kind of uptake maybe you've seen since July 1 now that these centers are able to bill Medicare?

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Pretty limited early in this quarter so far in that we had to get the sites up and running before they're in a position to bill it. So a lot of sites weren't even going through the full implementation process until they're able to really step in. And so now that Medicare is in place, we can say that's no longer a barrier. Now we get to lean in with a lot of those centers. Hence, that's really kind of the push into the third quarter here that's driving a lot of the guidance changes.

[Michael Sarcone, Analyst at Jefferies]

Great. That's really helpful. And then a follow-up on the growth in the accounts that did transition to INSPIRE V. You said over 20% growth 1H twenty five versus 1H twenty four. Can you just talk about the phenotype of those accounts and the characteristics?

[Michael Sarcone, Analyst at Jefferies]

Is there any reason why we shouldn't expect that analog to hold for kind of the average account for Inspire?

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Good question. I think the key is when we look at the accounts that were in our limited market release, obviously these are accomplished centers. But when we can see that kind of growth in the accomplished centers, the high volume centers already, yeah, we want to use that to translate in across the board into other centers to be able to show that kind of growth going forward. And we can use that as an example with centers to show that capacity increases by the reduced OR time and ease in during the programming with these patients. So yes, we want to reflect that across other centers as well and we'll communicate that to the centers and to our team.

[Michael Sarcone, Analyst at Jefferies]

Great. Thanks, Tim.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Thank you.

[Operator]

Thank you. And I show our next question comes from the line of Shagun Singh from RBC. Please go ahead.

[Shagun Singh, Medical Technology Analyst at RBC Capital Markets]

Great. Thank you for taking the question. I wanted to get a better sense of the implied Q4 guide. It assumes a substantial step up from Q3 to Q4, about 20% growth. And just what is your confidence in that number and that it won't be pushed into 2026?

[Shagun Singh, Medical Technology Analyst at RBC Capital Markets]

Any assumptions you can quantify for that would be helpful. And then just on Q3, I think somebody asked the question earlier, but can you give us a sense of volume growth that you've seen in July? Specifically, how many accounts have been converted? And lastly, just have you heard any pushback from customers around profitability? Thank you for taking the question.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

I'll go backwards. No, we haven't really seen any pressure from centers on profitability. I think that the new Medicare rates, the OPPS rules coming out, that really helps that off quite a bit. And I think the sixty four thousand five and '68 gives a little bit better reimbursement for ASCs. And again, that steps up again quite well going into 2026.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

So really not any too much pressure from that standpoint. Second question was? I'm sorry, Shagrin, what was the second question?

[Shagun Singh, Medical Technology Analyst at RBC Capital Markets]

So I was just wondering if you can comment on the Q4 guide, any quantification you can provide? And then also on July specifically, anything you can share on volume growth?

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Yes. I'm not in a position to really comment too much on the early July as we're new into the quarter right now. We did talk with Michael on the last question in regards to really leaning in to really get the other centers kind of up and running. And then when we look at the fourth quarter, remember that's the big quarter. That's the one where we have our seasonality because of the high deductible insurance plans.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

And so if you kind of look historically, we always get a pretty good step up from Q3 to Q4. And when we set our guide this time and we talked about the 1% to 3% step up from Q2 to Q3 and then what we had expect through Q3 to Q4 with that seasonality, that's how we set that overall guidance.

[Shagun Singh, Medical Technology Analyst at RBC Capital Markets]

Thank you.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Thank you.

[Operator]

Thank you. And I show our next question comes from the line of Anthony Petrone from Mizuho Americas. Please go ahead.

[Anthony Petrone, MD - Equity Research at Mizuho Financial Group]

Thanks. I'm going to go into three quick ones, rattle them off on some of the headwinds here. One is capacity and then you talked about sleep sync and then GLP-one. So on the capacity side, maybe just an idea of where general surgeons can be as a channel heading into '26. On sleep sync, can it be fully up and running to all accounts by the end of the year?

[Anthony Petrone, MD - Equity Research at Mizuho Financial Group]

And if so, what does that do in terms of unlocking channel? And then a failed dice going to GLP-one, how often does that happen? In the experience so far, have you gotten any of those patients back at this point? Thanks.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Absolutely. Good question. Thank you. From a capacity standpoint, the first step that we're doing is with existing centers and making sure that they understand the improved capacities with Inspire five. We just talked about the demonstrated over 20% increase already in the sites in the limited market release.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

But we do think that the next step is going to be added ENTs, both those that were reluctant to do procedures based on the pressure sensing lead or those that were trained and really haven't really engaged and done a lot of procedures. And we believe the pressure sensing lead has a factor in that and that we can improve it. Then we can move forward and talk about both oral surgeons who do maxillomandibular advancements and even general surgeons. Now that we don't have that pressure sensing need, it can lend to improved adoption by general surgeons. We do have a few that are already doing that and quite successful with that.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Going to your second question on SleepSync. SleepSync is a long term view. It's our cloud based patient management system. And it is what is going to provide improved patient outcomes because it's going to help sleep physicians with the monitoring and programming and care of their patients from a longitudinal standpoint. And having that as part of the INSPIRE-five system is another conduit to be able to have data into the sleep sync overall.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

So it is a very important part of it. Yes, we plan to have the majority of the sites all up on sleepsync. Site who will be doing INSPIRE V will be up on sleep sync. There may be a few sites that will continue with four. But I think a great majority of sites will have sleep sync implemented.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

And that really provides a long term benefit both to the centers, especially to the patients because we can monitor their outcomes. And of course, for INSPIRE because it is a competitive edge as well. And then finally, GLP-1s, the failed dice. As you know with the predictor study, we're saying that we now have an algorithm for patients who have a BMI less than thirty two, that we can use the BMI of thirty two and a neck circumference to predict their qualifications for INSPIRE and therefore eliminate a sleep endoscopy for those patients with a higher BMI. And when you start to get a BMI up at about thirty five, it could be as high as fifty percent of patients would have a large enough neck circumference to have complete concentric collapse.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

And those patients need to lose weight so we can reduce the lateral wall collapse and be able to treat them with a tongue based collapse or hypoglossal nerve stimulation.

[Operator]

Thank you. And I show our next question in the queue comes from the line of Chris Pasquale from Nephron Research. Please go ahead.

[Chris Pasquale, Partner - Medical Devices & Supplies at Nephron Research LLC]

Thanks. I had a couple of Tim, I want to start off just taking a different spin on Shagun's question. To your point, up low single digits in 3Q, then up 20% plus in 4Q. That's very similar to what we've seen in the past couple of years. I guess my question is, should this year follow the typical seasonality?

[Chris Pasquale, Partner - Medical Devices & Supplies at Nephron Research LLC]

It seems like many of the headwinds you called out are going to be peaking here in 3Q. It's going take you some time to realize the benefit from ramping back up the DTC spend. So why shouldn't we expect 3Q to be weaker than usual and then maybe even have a steeper ramp in the year end than we might typically see?

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Sure. I think what we said in Q3, it's going to be above 1% to 3%. Historically, you kind of look at it, it's usually a little bit higher than that maybe coming out of Q2 and so it's a little softer in our guide as we mentioned, but then we put the consistent step up going into Q4. So the key is going to be we just need to keep focus on the corrective actions that we have in place and all the actions to be able to get the patient flow going. And you're correct, the DTC does have more of a longer term impact both into Q4 and then of course, setting up for 2026.

[Chris Pasquale, Partner - Medical Devices & Supplies at Nephron Research LLC]

Okay. And then you said you haven't heard a lot of pushback on reimbursement yet. One of the things that we have heard from some high volume physicians is that the lower payment rate from Medicare patients under the new CPT code makes it less attractive for them to treat that population. And they're thinking about deemphasizing that cohort in their own practice. So how confident are you that everything we're seeing here is really just a matter of getting all the pieces in place so that it's easy to do the billing and not a broader issue around those patients getting served?

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

That's a good point. And so we need to continue to communicate that the difference between the old code 64582, the new code 64568 did have a $200 Medicare gap. And we also think that's reflective in the work that they do not have to put in the pressure sensing lead. So it is a reduction in time and the reimbursement per minute for the high level implanters, the experienced implanters will be awash. Now the good news is with the OPPCS rules coming out, there's a $600 increase in $64,568 There was a slight decrease in $64,582 We're not too concerned about that.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

That needs a little bit more review. But it really has significantly reduced that gap. Nonetheless, with an increase to $660 proposed with 64,568 And with the experience that they can get with a reduced OR time, it should increase their capacity. We believe, and as we've shown with our initial sites, patient flow and implant volume has increased over 20 with the first limited market release site. So I think we'll be able to work with the surgeons, communicate that and get their commitment to take care of patients.

[Chris Pasquale, Partner - Medical Devices & Supplies at Nephron Research LLC]

Thanks.

[Operator]

Thank you. And I show our next question comes from the line of Larry Biegelsen from Wells Fargo. Please go ahead.

[Lawrence Biegelsen, Senior Medical Device Equity Research Analyst at Wells Fargo]

Hi, good afternoon. Thanks for taking the question. Hey, Tim, I think some of us, maybe just me, might be struggling to understand how the delay in INSPIRE V negatively impacted Q2, because INSPIRE V doesn't really have a clinical benefit over INSPIRE IV. So I wanted to run the factors that impacted Q2 that I heard on this call by you to see if I'm missing anything. So Q2, it sounds like, was negatively impacted by patients who are waiting for Inspire five, one, some burning down of Inspire four inventory, lower hires and center edge and some impact from GLP-one trialing.

[Lawrence Biegelsen, Senior Medical Device Equity Research Analyst at Wells Fargo]

Is that kind of the right way to think about why The U. S. Growth in Q2 was 10%?

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Yes. But yes, and we communicated that on the Q1 call, what we expect out of Q2 and that's what we delivered.

[Lawrence Biegelsen, Senior Medical Device Equity Research Analyst at Wells Fargo]

Okay. And the GLP-1s, what makes you think the impact is temporary and short lived? Why couldn't it get worse from here? And do you have any visibility on Dice test growth, like the top of the funnel? Thanks.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Thanks, Larry. We do monitor the DICE growth and when they get scheduled, but we do track from the top of the funnel all the way through. And when we just communicate with some of our sites, that's where we get the anecdotal feedback that some patients may be trialing it. We do think with the focused effort on the high BMI patients with DICE and the cognitive effort to get those patients to help them lose weight with BMI, they're being proactive around that to offset any challenge we may have with GLP-1s. But of course, we'll, to your point, monitor that very closely to see how patients are doing with the GLP-1s.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

But again, the data to date really shows that it has the best impact with the high BMI patients and lower BMI patients don't really have the lateral wall collapse. They're the tongue based collapse that is treated with Inspire therapy and those are the patients that we are targeting.

[Lawrence Biegelsen, Senior Medical Device Equity Research Analyst at Wells Fargo]

All right. Thanks, Tim.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Thanks, Larry.

[Operator]

Thank you. And I show our next question comes from the line of Jon Block from Stifel. Please go ahead.

[Jonathan Block, Managing Director at Stifel Financial Corp]

Thanks, guys. Good afternoon. Maybe just to break it apart, are you going to sell Inspire four in 2026 in The U. S? And when we think about the revised guidance, is the four inventory arguably cleaned up or depleted, if you would, Tim, in your opinion, by the 2025? And then I'll just try to ask a follow-up.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Yeah, well, we're going to continue to have Inspire four available both in Europe and in Asia and in The United States for select sites that would like to remain using Inspire for. So it is going to be available. The real challenge is managing the inventory in Europe because remember how long it takes to be able to get the EU MDR approval. And so that's really the number one reserve we have with that inventory. And then we'll monitor in 2026 how much inventory we even have to be able to use in The US.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

And we'll have better answers and more clarity around that as we work through the year.

[Jonathan Block, Managing Director at Stifel Financial Corp]

Okay. Thanks for that. And then, Rick, I'll take a third shot at the EPS. So the way I look at it is that the GAAP EPS is essentially flat year to date essentially. And then you've got a 40 to 50¢ guide in GAAP EPS for the year.

[Jonathan Block, Managing Director at Stifel Financial Corp]

So you have interest income. I'm backing into, like call it low single digit EBIT margins in the back part of 2025. The gross margins are unchanged, the guide. So it's just OpEx as a percent of sales that moves much higher in 2H twenty five? I guess that's part one.

[Jonathan Block, Managing Director at Stifel Financial Corp]

Is that correct? And then is that also what's going to drive, Tim, in your view, the 2026 revenue acceleration because there's a good amount going into SG and A, DTC, etcetera, as we exit the back part of this year. Hope that made sense. Thanks, Gus.

[Rick Buchholz, Chief Financial Officer at Inspire Medical Systems]

Yeah, John, that driver is really increased operating expenses. With our previous guidance, operating expenses increased around 16% over 2024. Now with our revised earnings per share, if you work backwards, that overall OpEx growth inclusive of a couple adjusted items is 18%.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

And yes, I think the increase in our marketing and increase of the footprint is exactly the way as you described to be able to continue to excite patient flow and move forward into 2026. Yes, John, we fully remain committed to profitability.

[Jonathan Block, Managing Director at Stifel Financial Corp]

Thank you.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Thanks, John.

[Operator]

And I show our next question comes from the line of Brett Fishman from KeyBanc Capital Markets. Please go ahead.

[Brett Fishbin, VP - Senior Equity Research Analyst at KeyBanc Capital Markets]

Hey, guys. Thanks for taking the questions and for fitting me in here. Just I'll have to follow-up to this EPS topic. So you mentioned that part of the revision has to do with investments in both marketing and footprint expansion. Was just curious if you could provide a little bit more specific color on what spending in those buckets is incremental versus the prior range?

[Brett Fishbin, VP - Senior Equity Research Analyst at KeyBanc Capital Markets]

So like what's being added to the budget versus what was previously assumed coming out of 1Q? Thank you.

[Rick Buchholz, Chief Financial Officer at Inspire Medical Systems]

Yeah, Brett. The real driver there is that we want to continue to build patient awareness. And so it's going to be our DTC spend that we're going to have increased awareness to really take advantage of the launch and kind of amplify our messaging as we said in our prepared remarks. We did intentionally hold off on DTC in the first real half of the year and just to focus on the launch, but so now we're ramping up those efforts here in second half of the year. We are still going to do some other spending on other marketing areas as well.

[Rick Buchholz, Chief Financial Officer at Inspire Medical Systems]

And we're going to continue to add territories as we've done in the past. And so those are the continued investments that we want to make. Like So as Tim said, we remain committed to improving long term profitability.

[Brett Fishbin, VP - Senior Equity Research Analyst at KeyBanc Capital Markets]

Thank you.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Thanks, Brett.

[Operator]

Thank you. And I show our last question comes from the line of Michael Polarc from Wolfe Research. Please go ahead.

[Mike Polark, Senior Equity Research Analyst - Medical Devices at Wolfe Research, LLC]

Hey, good afternoon.

[Mike Polark, Senior Equity Research Analyst - Medical Devices at Wolfe Research, LLC]

Probably for Rick. For the full year the updated full year guidance, $9.00 5,000,000 at the midpoint, What is the net inventory destocking headwind in that number? So four comes down centers that start on five ramp those units back up a little bit, but it sounds like there's a net negative impact in this updated guidance. And I'm wondering what that number is for the full year.

[Rick Buchholz, Chief Financial Officer at Inspire Medical Systems]

We have not factored that into our guidance at all. We have increased our inventory balances because we want to have INSPIRE V fully available. And so Wait a second, destocking. Stocking.

[Ezgi Yagci, VP - IR at Inspire Medical Systems]

Right. So destocking is factored into our updated back half guidance. We did not quantify it, and it would be very difficult to do so. Keep in mind, there's also a timing element here. So, depending on when that center transitions to INSPIRE V and destocks their INSPIRE IV, so there could be some timing element.

[Ezgi Yagci, VP - IR at Inspire Medical Systems]

But that is factored into the outlook we gave for the back half of the year.

[Mike Polark, Senior Equity Research Analyst - Medical Devices at Wolfe Research, LLC]

Yeah. And that's what I was driving to. I can understand for 2H why there would be a headwind on the timing, but at some point it'll work. It's I would think it works its way back to neutral. So if there's a number you wanted to call out for the full year, I'd be happy to receive it.

[Mike Polark, Senior Equity Research Analyst - Medical Devices at Wolfe Research, LLC]

And where I'm going is I'm trying to visualize the path back to higher than 12% to 13% growth in 2026. And one of the things that might not recur next year that is impairing growth this year is this item. And if there was a quantification of it, it'd be helpful to envision the reacceleration.

[Ezgi Yagci, VP - IR at Inspire Medical Systems]

Understood. We're not prepared to give that number at this time, but we'll take that under consideration as we provide guidance for next year.

[Mike Polark, Senior Equity Research Analyst - Medical Devices at Wolfe Research, LLC]

Okay. I appreciate that. If I can sneak one more in. I know this is a number you're not giving, but again, I think it could be helpful for kind of the new vision from here after the reset. So would you be willing to share at June 30 how many centers were active implanting in The US? I know the last number we got was fourteen thirty five at 12:31. Just be great to understand like how much center activation was really suppressed in the first part of the year due to all the launch activities.

[Ezgi Yagci, VP - IR at Inspire Medical Systems]

It is slightly higher. Let's just say it's a little over 1,500 right now. So, we did still continue to open new centers in the early part of this year, but not at the same rate that we did in 2024. Again, with the INSPIRE V transition underway, we did not want new center openings to distract the field, but we did continue to add centers, just not at the same rate. And Mike, congratulations on your firstborn.

[Mike Polark, Senior Equity Research Analyst - Medical Devices at Wolfe Research, LLC]

Thank you, thank you.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

Very good. Thanks Mike. As always, I'm grateful to the growing team of dedicated Inspire employees for their enthusiasm, hard work, and continued motivation to achieve successful and consistent patient outcomes. Team's commitment to patients remains unmatched and is the most important element to our success.

[Tim Herbert, Chairman, President & CEO at Inspire Medical Systems]

I wish to thank all of our employees as well as the healthcare teams for their continued efforts as we remain focused on further expanding our business in The U. S, in Europe and in Asia. For all of you on the call, we appreciate your continued interest in and support of Inspire and look forward to providing you with further updates in the months ahead.

[Operator]

Thank you. This concludes today's conference call. You may now disconnect.

Participants

Executives

• Ezgi Yagci, VP - IR
• Tim Herbert, Chairman, President & CEO
• Rick Buchholz, Chief Financial Officer

Analysts

• Adam Maeder, MD & Senior Research Analyst at Piper Sandler Companies
• Travis Steed, MD - Equity Research at Bank of America
• Danielle Antalffy, Analyst at UBS Group
• Robert Marcus, Senior Analyst at JPMorgan Chase
• Richard Newitter, Managing Director at Truist Securities
• David Rescott, Senior Research Analyst at Baird
• Michael Sarcone, Analyst at Jefferies
• Shagun Singh, Medical Technology Analyst at RBC Capital Markets
• Anthony Petrone, MD - Equity Research at Mizuho Financial Group
• Chris Pasquale, Partner - Medical Devices & Supplies at Nephron Research LLC
• Lawrence Biegelsen, Senior Medical Device Equity Research Analyst at Wells Fargo
• Jonathan Block, Managing Director at Stifel Financial Corp
• Brett Fishbin, VP - Senior Equity Research Analyst at KeyBanc Capital Markets
• Mike Polark, Senior Equity Research Analyst - Medical Devices at Wolfe Research, LLC