NASDAQ:PRLD Prelude Therapeutics Q4 2025 Earnings Results & Report $3.32 +0.09 (+2.79%) Closing price 04:00 PM EasternExtended Trading$3.32 0.00 (0.00%) As of 04:51 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Prelude Therapeutics beat analyst earnings expectations but missed on revenue in its Q4 2025 results, released March 10, 2026. The company reported EPS of -$0.20 versus the -$0.33 consensus estimate, while revenue of $5.64 million fell short of the $20.50 million estimate by $14.86 million. Research:ProfileEarnings HistoryForecast Earnings Announcement Details QuarterQ4 2025Report DateMarch 10, 2026TimeBefore Market Opens Prelude Therapeutics EPS ResultsActual EPS-$0.20Consensus EPS -$0.33Beat/MissBeat by +$0.13One Year Ago EPSN/AEPS Beat Rate8 of last 8 quartersPrelude Therapeutics Revenue ResultsActual Revenue$5.64 millionExpected Revenue$20.50 millionBeat/MissMissed by -$14.86 millionYoY Revenue GrowthN/AUpcoming EarningsPrelude Therapeutics' Q3 2026 earnings is estimated for Wednesday, November 11, 2026, based on past reporting schedules, with a conference call scheduled at 8:00 AM ET. Check back for transcripts, audio, and key financial metrics as they become available.Q3 2026 Earnings ReportConference Call ResourcesPress Release (8-K)Annual Report (10-K)Earnings HistoryCompany ProfilePowered by Earnings DocumentsPress Release(8-K)Annual report(10-K) Prelude Therapeutics Q4 2025 Earnings FAQ Did Prelude Therapeutics beat earnings estimates for Q4 2025? Prelude Therapeutics (NASDAQ:PRLD) reported earnings of -$0.20 per share for Q4 2025, beating the consensus estimate of -$0.33. The report was announced on Tuesday, March 10, 2026. What was Prelude Therapeutics' revenue for Q4 2025? Prelude Therapeutics reported revenue of $5.64 million for Q4 2025, against a consensus estimate of $20.50 million. When is Prelude Therapeutics' next earnings date? Prelude Therapeutics' next earnings date is estimated for Wednesday, November 11, 2026. MarketBeat tracks confirmed and estimated earnings dates for Prelude Therapeutics on the company's earnings history page. Prelude Therapeutics Earnings HeadlinesPrelude Therapeutics Incorporated Proceeds With Phase 1 Study Of PRT13722 In Patients With HR+/HER2- Breast CancerOctober 14 at 7:49 PM | marketscreener.comMPrelude Announces Clinical Trial Collaboration and Supply Agreement with Lilly to Evaluate KAT6A Selective Degrader PRT13722 in Combination with Verzenio® and Inluriyo® in ...October 13 at 8:59 AM | markets.businessinsider.comHere’s the stock symbol I’ve promisedWhitney Tilson of Stansberry Research has long recommended Berkshire Hathaway as a core retirement holding - but now he believes he's found something better. This under-the-radar company sits at the intersection of America's two most important industries, including AI, pays massive dividends, and attracted a famous money manager who put 60% of his multi-billion-dollar fund into it. Tilson is revealing the name and ticker symbol completely free - no credit card or email required.October 15 at 1:00 AM | Stansberry Research (Ad)Prelude, Lilly Partner On Breast Cancer Combination Trial; Stock UpOctober 13 at 8:59 AM | rttnews.comPrelude Therapeutics, Eli Lilly to Study Breast Cancer Drug Combinations in Phase 1 TrialOctober 13 at 8:59 AM | finance.yahoo.comPrelude Announces Clinical Trial Collaboration and Supply Agreement with Lilly to Evaluate KAT6A Selective Degrader PRT13722 in Combination with Verzenio® and Inluriyo® in Patients with HR+/HER2- Breast CancerOctober 13 at 7:01 AM | globenewswire.comSee More Prelude Therapeutics Headlines Get Earnings Announcements in your inboxWant to stay updated on the latest earnings announcements and upcoming reports for companies like Prelude Therapeutics? Sign up for Earnings360's daily newsletter to receive timely earnings updates on Prelude Therapeutics and other key companies, straight to your email. Email Address About Prelude TherapeuticsPrelude Therapeutics (NASDAQ:PRLD) Inc. is a clinical-stage biopharmaceutical company focused on developing precision medicines for cancer. The company uses cancer biology, medicinal chemistry and targeted drug-discovery approaches to identify small-molecule therapies designed to address genetic and molecular vulnerabilities in tumors. Prelude’s investigational pipeline has included PRT3789, a selective SMARCA2 protein degrader being developed for cancers with SMARCA4 loss, and PRT2527, a selective cyclin-dependent kinase 9 (CDK9) inhibitor under evaluation for oncology applications. These programs are investigational and are not approved for commercial use. Founded in 2016 and headquartered in Wilmington, Delaware, Prelude conducts research and clinical development activities in the United States. The company was founded by David Mack, Ph.D., who has served as its president and chief executive officer. As a clinical-stage biotechnology company, Prelude’s operations are primarily focused on advancing its drug candidates through clinical testing and establishing potential treatment options for patients with cancer.View Prelude Therapeutics ProfileRead more More Earnings Resources from MarketBeat Earnings Tools Today's Earnings Tomorrow's Earnings Next Week's Earnings Upcoming Earnings Calls Earnings Newsletter Earnings Call Transcripts Earnings Beats & Misses Corporate Guidance Earnings Screener Latest Articles Apple Cut iPhone 18 Orders; What Does It Mean For Suppliers?Domino’s Pizza: As Cheap As It Gets, Nowhere to Go But UpFastenal Flashes Bullish Signal as Uptrend Holds Despite Margin PressureASML Can’t Keep Up With AI Demand—Why That's a Good ThingCiti Stock Falls Despite Earnings Beat: What Investors Need to KnowDon’t Get NVIDIA’s Reflection AI Interest Wrong: Its Moat Could DeepenBig Banks Report Strong Earnings—So Why Are Shares Falling? 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