NASDAQ:SEPN Septerna Q4 2025 Earnings Report $38.51 +0.76 (+2.01%) Closing price 09/11/2026 04:00 PM EasternExtended Trading$38.88 +0.37 (+0.95%) As of 09/11/2026 07:30 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. ProfileEarnings HistoryForecast Septerna EPS ResultsActual EPS-$0.24Consensus EPS -$0.23Beat/MissMissed by -$0.01One Year Ago EPSN/ASepterna Revenue ResultsActual RevenueN/AExpected Revenue$20.44 millionBeat/MissN/AYoY Revenue GrowthN/ASepterna Announcement DetailsQuarterQ4 2025Date3/9/2026TimeBefore Market OpensConference Call DateN/AConference Call TimeN/AUpcoming EarningsSepterna's Q3 2026 earnings is estimated for Monday, November 9, 2026, based on past reporting schedules, with a conference call scheduled on Tuesday, November 10, 2026 at 4:00 PM ET. Check back for transcripts, audio, and key financial metrics as they become available.Conference Call ResourcesPress Release (8-K)Annual Report (10-K)Earnings HistoryCompany ProfilePowered by Earnings DocumentsPress Release(8-K)Annual report(10-K) Septerna Earnings HeadlinesSepterna, Inc. Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)September 10 at 4:00 PM | globenewswire.comSepterna to Participate in Upcoming Investor ConferencesSeptember 1, 2026 | globenewswire.comWhy I'm NOT Buying the SpaceX IPO (And What I'm Buying Instead)Don't buy Nvidia... Not when the AI companies that will define the next decade are selling for pennies. You won't find them on any stock exchange. The big funds already know this... Their focus has shifted to a subsegment they call decentralized AI. They're launching tokens in the native markets. This is where coins list months before Coinbase, Kraken, or Robinhood… because raising from millions of investors beats begging a handful of funds. This is the world's first open venture capital market… a teacher in Ohio investing at the same stage as a billionaire in Singapore. Watch the free training on how to access the native markets (and buy potential AI unicorns before major exchange listings).September 12 at 1:00 AM | Decentralized Masters (Ad)Septerna names Rajiv Patni as CMOAugust 25, 2026 | msn.comSepterna Appoints Rajiv Patni as Chief Medical OfficerAugust 25, 2026 | tipranks.comSepterna Appoints Industry Veteran Rajiv Patni, M.D., as Chief Medical OfficerAugust 25, 2026 | globenewswire.comSee More Septerna Headlines Get Earnings Announcements in your inboxWant to stay updated on the latest earnings announcements and upcoming reports for companies like Septerna? Sign up for Earnings360's daily newsletter to receive timely earnings updates on Septerna and other key companies, straight to your email. Email Address About SepternaSepterna (NASDAQ:SEPN) is a clinical-stage biotechnology company focused on discovering and developing oral small-molecule medicines that target G protein-coupled receptors (GPCRs). GPCRs are a large class of cell-surface proteins involved in numerous biological processes and are established targets for therapies across a range of diseases. The company uses its proprietary Native Orthosteric Ligand Discovery platform to study GPCRs in their native cellular environments and identify small-molecule compounds that can modulate these receptors. Septerna’s research and development efforts are directed toward potential treatments in areas including immunology, inflammation, metabolic disease and other conditions with significant unmet medical needs. Septerna was founded to advance GPCR-directed drug discovery and became a publicly traded company on the Nasdaq under the symbol SEPN. The company is based in the United States and is focused primarily on advancing its internal discovery and clinical-stage pipeline rather than marketing approved products.View Septerna ProfileRead more More Earnings Resources from MarketBeat Earnings Tools Today's Earnings Tomorrow's Earnings Next Week's Earnings Upcoming Earnings Calls Earnings Newsletter Earnings Call Transcripts Earnings Beats & Misses Corporate Guidance Earnings Screener Latest Articles MarketBeat Week in Review – 09/07 - 09/11Kroger’s Textbook Entry for Buy-and-Hold InvestorsOracle’s AI Spending Is Still Huge, But the Payoff Is Starting to Show in EarningsAmgen Drops 10% on a Trial It Didn't Even RunOil Above $100 Is Creating a New Opportunity Beyond the Major ProducersAST SpaceMobile Looks to Extend Its 30-Day FCC Satellite Testing WindowAmerican Eagle Goes on Sale: Is It Time to Buy? 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