NASDAQ:ACTU Actuate Therapeutics (ACTU) Stock Price, News & Analysis $0.88 -0.02 (-2.46%) As of 01:44 PM Eastern This is a fair market value price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsInsider TradesNews and TrendsOwnershipSEC Filings About Actuate Therapeutics Stock (NASDAQ:ACTU) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Actuate Therapeutics alerts:Sign Up Key Stats Today's Range$0.84▼$0.9350-Day Range$0.91▼$1.7852-Week Range$0.84▼$8.49Volume123,797 shsAverage Volume209,716 shsMarket Capitalization$21.25 millionP/E RatioN/ADividend YieldN/APrice Target$10.50Consensus RatingHold Company Overview Actuate Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing therapies for cancer and other serious diseases. The company’s research is centered on glycogen synthase kinase-3 beta (GSK-3β), a signaling protein involved in tumor growth, inflammation and immune regulation. Actuate’s lead investigational product is elraglusib, also known as 9-ING-41, a small-molecule inhibitor of GSK-3β. The therapy has been evaluated in clinical studies involving patients with hematologic malignancies and solid tumors, including pancreatic cancer, as the company investigates its potential to improve outcomes when used alone or in combination with other treatments. The company is advancing elraglusib through clinical development and continues to study its potential applications in oncology and inflammatory or immune-related conditions. As a development-stage biotechnology company, Actuate’s products remain investigational and are not established as approved commercial therapies.AI Generated. May Contain Errors. Read More Actuate Therapeutics Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks53rd Percentile Overall ScoreACTU MarketRank™: Actuate Therapeutics scored higher than 53% of companies evaluated by MarketBeat, and ranked 447th out of 898 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion3.8 / 5Analyst RatingHold Consensus RatingActuate Therapeutics has received a consensus rating of Hold. The company's average rating score is 2.33, and is based on no strong buy ratings, 2 buy ratings, no hold ratings, and 1 sell rating.Upside PotentialActuate Therapeutics has a consensus price target of $10.50, representing about 1,083.8% upside from its current price of $0.89.Amount of Analyst CoverageActuate Therapeutics has only been the subject of 3 research reports in the past 90 days.Read more about Actuate Therapeutics' stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthGrowing Earnings GrowthEarnings for Actuate Therapeutics are expected to grow in the coming year, from ($0.73) to ($0.59) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Actuate Therapeutics is -1.02, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Actuate Therapeutics is -1.02, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioActuate Therapeutics has a P/B Ratio of 2.61. P/B Ratios below 3 indicates that a company is reasonably valued with respect to its assets and liabilities. Short Interest2.0 / 5Short Interest LevelBearish Percentage of Shares Shorted11.62% of the float of Actuate Therapeutics has been sold short.Short Interest Ratio / Days to CoverActuate Therapeutics has a short interest ratio ("days to cover") of 1.92, which is generally considered an acceptable ratio of short interest to trading volume.Change versus previous monthShort interest in Actuate Therapeutics has recently increased by 68.50%, indicating that investor sentiment is decreasing significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldActuate Therapeutics does not currently pay a dividend.Dividend GrowthActuate Therapeutics does not have a long track record of dividend growth. News and Social Media2.8 / 5News Sentiment0.51 News SentimentActuate Therapeutics has a news sentiment score of 0.51. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This news sentiment score is similar to the average news sentiment of Healthcare companies.News Coverage This WeekMarketBeat has tracked 2 news articles for Actuate Therapeutics this week, compared to 3 articles on an average week.Search Interest6 people have searched for ACTU on MarketBeat in the last 30 days. This is an increase of 500% compared to the previous 30 days.MarketBeat Follows2 people have added Actuate Therapeutics to their MarketBeat watchlist in the last 30 days. Company Ownership0.7 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, Actuate Therapeutics insiders have not sold or bought any company stock.Percentage Held by Insiders57.98% of the stock of Actuate Therapeutics is held by insiders. A high percentage of insider ownership can be a sign of company health.Percentage Held by InstitutionsActuate Therapeutics has minimal institutional ownership at this time.Read more about Actuate Therapeutics' insider trading history. 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Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. ACTU Stock News HeadlinesActuate Therapeutics, Inc. (NASDAQ:ACTU) Sees Significant Increase in Short InterestSeptember 17, 2026 | americanbankingnews.comActuate Therapeutics consensus price target decreased by 33.33% to $11.90September 15, 2026 | msn.comPass by August 7… or wait until 2027?On August 14, federal regulators cleared a national trust bank tied to the Trump family's crypto venture. Warren called it the most brazen act of self-dealing our financial system has ever seen… and announced legislation to bar presidents and senior officials from owning or controlling banks. The bank in question exists to issue and back USD1, a stablecoin that has now crossed $4 billion in circulation. The Trump family holds 38% of the parent company. And the approval stands. So there's a race on now. This ecosystem scaling up, against Washington players like Warren scrambling to slow it down.September 22 at 1:00 AM | Crypto 101 Media (Ad)Actuate to Present at the H.C. Wainwright 28th Annual Global Investment ConferenceSeptember 9, 2026 | globenewswire.comActuate Therapeutics: Actuate Announces Promising Preclinical Data Showing Synergistic Activity of Elraglusib in Combination with RAS Inhibitors Zoldonrasib and DaraxonrasibSeptember 9, 2026 | finanznachrichten.deActuate Announces Promising Preclinical Data Showing Synergistic Activity of Elraglusib in Combination with RAS Inhibitors Zoldonrasib and DaraxonrasibSeptember 9, 2026 | globenewswire.comActuate Therapeutics’ Elraglusib Selected for Evaluation in BEACON2 Trial for High-Risk Pediatric NeuroblastomaJune 9, 2026 | markets.businessinsider.comActuate Therapeutics' Elraglusib Selected for Evaluation in BEACON2 Trial for High-Risk Pediatric NeuroblastomaJune 9, 2026 | globenewswire.comSee More Headlines ACTU Stock Analysis - Frequently Asked Questions How have ACTU shares performed this year? Actuate Therapeutics' stock was trading at $6.12 at the start of the year. Since then, ACTU shares have decreased by 85.5% and is now trading at $0.8870. How were Actuate Therapeutics' earnings last quarter? Actuate Therapeutics, Inc. (NASDAQ:ACTU) posted its earnings results on Friday, August, 14th. The company reported ($0.20) earnings per share (EPS) for the quarter, beating the consensus estimate of ($0.21) by $0.01. When did Actuate Therapeutics IPO? Actuate Therapeutics (ACTU) raised $27 million in an initial public offering (IPO) on Tuesday, August 13th 2024. The company issued 3,000,000 shares at $8.00-$10.00 per share. Titan Partners acted as the underwriter for the IPO and Newbridge Securities Corp. was co-manager. Who are Actuate Therapeutics' major shareholders? Top institutional investors of Actuate Therapeutics include Texas Capital Bank Wealth Management Services Inc (0.43%), Palogic Value Management L.P. (0.42%), BlackRock Inc. (0.38%) and ABS Investment Management LLC (0.31%). Insiders that own company stock include Todd S Thomson, Leslie W Kreis, Equity Cof Lp Bios and Aaron GL Fletcher. View institutional ownership trends. How do I buy shares of Actuate Therapeutics? Shares of ACTU stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Actuate Therapeutics own? Based on aggregate information from My MarketBeat watchlists, some other companies that Actuate Therapeutics investors own include Arch Capital Group (ACGL), Adobe (ADBE), Analog Devices (ADI), Alnylam Pharmaceuticals (ALNY), Amgen (AMGN) and Company Calendar Last Earnings8/14/2026Today9/22/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Yellow Zone (1w+) 1-Year History Sep 25 Dec 25 Mar 26 Jun 26 Sep 26 For the last 8 days, ACTU's financial health has been in the Yellow zone, according to TradeSmith. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorHealthcare Industry Pharmaceuticals Sub-IndustryPharmaceuticals Current SymbolNASDAQ:ACTU Previous SymbolNASDAQ:ACTU CIK1652935 Webactuatetherapeutics.com Phone(847) 986-4190FaxN/AEmployees12Year Founded2015Price Target and Rating Average Price Target for Actuate Therapeutics$10.50 High Price Target$15.00 Low Price Target$6.00 Potential Upside/Downside+1,086.4%Consensus RatingHold Rating Score (0-4)2.33 Research Coverage3 Analysts Profitability EPS (Trailing Twelve Months)($0.87) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$22.23 million Net MarginsN/A Pretax MarginN/A Return on Equity-346.19% Return on Assets-178.40% Debt Debt-to-Equity RatioN/A Current Ratio1.25 Quick Ratio1.25 Sales & Book Value Annual SalesN/A Price / SalesN/A Cash FlowN/A Price / Cash FlowN/A Book Value$0.34 per share Price / Book2.60Miscellaneous Outstanding Shares24,010,000Free Float10,091,000Market Cap$21.25 million OptionableN/A Beta0.95 Social Links 7 Stocks to Buy Before the Robotics RevolutionRobotics and automation are rapidly becoming essential infrastructure across healthcare, manufacturing, logistics, and many other industries. 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