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Actuate Therapeutics (ACTU) Competitors

Actuate Therapeutics logo
$2.02 0.00 (0.00%)
Closing price 06/12/2026 04:00 PM Eastern
Extended Trading
$1.98 -0.03 (-1.73%)
As of 06/12/2026 07:56 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

ACTU vs. ARTV, OKUR, IPHA, ABOS, and CNTN

Should you buy Actuate Therapeutics stock or one of its competitors? MarketBeat compares Actuate Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Actuate Therapeutics include Artiva Biotherapeutics (ARTV), OnKure Therapeutics (OKUR), Innate Pharma (IPHA), Acumen Pharmaceuticals (ABOS), and Hillstream Biopharma (CNTN). These companies are all part of the "pharmaceutical products" industry.

How does Actuate Therapeutics compare to Artiva Biotherapeutics?

Actuate Therapeutics (NASDAQ:ACTU) and Artiva Biotherapeutics (NASDAQ:ARTV) are both small-cap medical companies, but which is the superior investment? We will contrast the two businesses based on the strength of their analyst recommendations, dividends, profitability, earnings, institutional ownership, media sentiment, valuation and risk.

Actuate Therapeutics has a beta of 0.53, indicating that its stock price is 47% less volatile than the broader market. Comparatively, Artiva Biotherapeutics has a beta of 2.4, indicating that its stock price is 140% more volatile than the broader market.

In the previous week, Artiva Biotherapeutics had 8 more articles in the media than Actuate Therapeutics. MarketBeat recorded 11 mentions for Artiva Biotherapeutics and 3 mentions for Actuate Therapeutics. Artiva Biotherapeutics' average media sentiment score of 0.91 beat Actuate Therapeutics' score of 0.62 indicating that Artiva Biotherapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Actuate Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Artiva Biotherapeutics
2 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Artiva Biotherapeutics' return on equity of -73.15% beat Actuate Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Actuate TherapeuticsN/A -430.93% -180.86%
Artiva Biotherapeutics N/A -73.15%-62.74%

Actuate Therapeutics has higher earnings, but lower revenue than Artiva Biotherapeutics. Artiva Biotherapeutics is trading at a lower price-to-earnings ratio than Actuate Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Actuate TherapeuticsN/AN/A-$22.23M-$0.97N/A
Artiva Biotherapeutics$250K844.44-$83.86M-$3.54N/A

Actuate Therapeutics presently has a consensus target price of $17.50, indicating a potential upside of 766.34%. Artiva Biotherapeutics has a consensus target price of $39.00, indicating a potential upside of 356.67%. Given Actuate Therapeutics' higher probable upside, equities research analysts plainly believe Actuate Therapeutics is more favorable than Artiva Biotherapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Actuate Therapeutics
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33
Artiva Biotherapeutics
1 Sell rating(s)
0 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.83

Summary

Artiva Biotherapeutics beats Actuate Therapeutics on 9 of the 13 factors compared between the two stocks.

How does Actuate Therapeutics compare to OnKure Therapeutics?

OnKure Therapeutics (NASDAQ:OKUR) and Actuate Therapeutics (NASDAQ:ACTU) are both small-cap medical companies, but which is the superior investment? We will contrast the two companies based on the strength of their valuation, earnings, analyst recommendations, dividends, risk, profitability, institutional ownership and media sentiment.

OnKure Therapeutics has a beta of 0.28, suggesting that its stock price is 72% less volatile than the broader market. Comparatively, Actuate Therapeutics has a beta of 0.53, suggesting that its stock price is 47% less volatile than the broader market.

91.0% of OnKure Therapeutics shares are owned by institutional investors. 17.9% of OnKure Therapeutics shares are owned by company insiders. Comparatively, 58.0% of Actuate Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

OnKure Therapeutics currently has a consensus target price of $27.00, suggesting a potential upside of 542.86%. Actuate Therapeutics has a consensus target price of $17.50, suggesting a potential upside of 766.34%. Given Actuate Therapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Actuate Therapeutics is more favorable than OnKure Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
OnKure Therapeutics
1 Sell rating(s)
2 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00
Actuate Therapeutics
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33

In the previous week, Actuate Therapeutics had 1 more articles in the media than OnKure Therapeutics. MarketBeat recorded 3 mentions for Actuate Therapeutics and 2 mentions for OnKure Therapeutics. OnKure Therapeutics' average media sentiment score of 0.94 beat Actuate Therapeutics' score of 0.62 indicating that OnKure Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
OnKure Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Actuate Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

OnKure Therapeutics' return on equity of -61.02% beat Actuate Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
OnKure TherapeuticsN/A -61.02% -55.99%
Actuate Therapeutics N/A -430.93%-180.86%

Actuate Therapeutics is trading at a lower price-to-earnings ratio than OnKure Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
OnKure TherapeuticsN/AN/A-$59.52M-$4.33N/A
Actuate TherapeuticsN/AN/A-$22.23M-$0.97N/A

Summary

Actuate Therapeutics beats OnKure Therapeutics on 8 of the 13 factors compared between the two stocks.

How does Actuate Therapeutics compare to Innate Pharma?

Actuate Therapeutics (NASDAQ:ACTU) and Innate Pharma (NASDAQ:IPHA) are both small-cap medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their media sentiment, valuation, risk, analyst recommendations, dividends, earnings, profitability and institutional ownership.

Actuate Therapeutics has higher earnings, but lower revenue than Innate Pharma.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Actuate TherapeuticsN/AN/A-$22.23M-$0.97N/A
Innate Pharma$10.19M16.22-$55.64MN/AN/A

Actuate Therapeutics currently has a consensus price target of $17.50, suggesting a potential upside of 766.34%. Innate Pharma has a consensus price target of $5.00, suggesting a potential upside of 184.09%. Given Actuate Therapeutics' higher probable upside, research analysts plainly believe Actuate Therapeutics is more favorable than Innate Pharma.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Actuate Therapeutics
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33
Innate Pharma
1 Sell rating(s)
1 Hold rating(s)
1 Buy rating(s)
1 Strong Buy rating(s)
2.50

0.2% of Innate Pharma shares are held by institutional investors. 58.0% of Actuate Therapeutics shares are held by insiders. Comparatively, 31.9% of Innate Pharma shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

In the previous week, Actuate Therapeutics had 2 more articles in the media than Innate Pharma. MarketBeat recorded 3 mentions for Actuate Therapeutics and 1 mentions for Innate Pharma. Innate Pharma's average media sentiment score of 1.89 beat Actuate Therapeutics' score of 0.62 indicating that Innate Pharma is being referred to more favorably in the news media.

Company Overall Sentiment
Actuate Therapeutics Positive
Innate Pharma Very Positive

Innate Pharma's return on equity of 0.00% beat Actuate Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Actuate TherapeuticsN/A -430.93% -180.86%
Innate Pharma N/A N/A N/A

Actuate Therapeutics has a beta of 0.53, meaning that its share price is 47% less volatile than the broader market. Comparatively, Innate Pharma has a beta of 0.31, meaning that its share price is 69% less volatile than the broader market.

Summary

Innate Pharma beats Actuate Therapeutics on 7 of the 13 factors compared between the two stocks.

How does Actuate Therapeutics compare to Acumen Pharmaceuticals?

Actuate Therapeutics (NASDAQ:ACTU) and Acumen Pharmaceuticals (NASDAQ:ABOS) are both small-cap medical companies, but which is the better stock? We will contrast the two companies based on the strength of their dividends, analyst recommendations, institutional ownership, risk, profitability, earnings, valuation and media sentiment.

Actuate Therapeutics currently has a consensus target price of $17.50, indicating a potential upside of 766.34%. Acumen Pharmaceuticals has a consensus target price of $6.67, indicating a potential upside of 181.29%. Given Actuate Therapeutics' higher probable upside, equities research analysts plainly believe Actuate Therapeutics is more favorable than Acumen Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Actuate Therapeutics
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33
Acumen Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.50

71.0% of Acumen Pharmaceuticals shares are owned by institutional investors. 58.0% of Actuate Therapeutics shares are owned by company insiders. Comparatively, 10.2% of Acumen Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

Actuate Therapeutics is trading at a lower price-to-earnings ratio than Acumen Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Actuate TherapeuticsN/AN/A-$22.23M-$0.97N/A
Acumen PharmaceuticalsN/AN/A-$121.33M-$1.86N/A

Actuate Therapeutics has a beta of 0.53, suggesting that its share price is 47% less volatile than the broader market. Comparatively, Acumen Pharmaceuticals has a beta of 0.34, suggesting that its share price is 66% less volatile than the broader market.

In the previous week, Acumen Pharmaceuticals had 1 more articles in the media than Actuate Therapeutics. MarketBeat recorded 4 mentions for Acumen Pharmaceuticals and 3 mentions for Actuate Therapeutics. Actuate Therapeutics' average media sentiment score of 0.62 beat Acumen Pharmaceuticals' score of 0.59 indicating that Actuate Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Actuate Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Acumen Pharmaceuticals
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Acumen Pharmaceuticals' return on equity of -123.07% beat Actuate Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Actuate TherapeuticsN/A -430.93% -180.86%
Acumen Pharmaceuticals N/A -123.07%-79.41%

Summary

Acumen Pharmaceuticals beats Actuate Therapeutics on 7 of the 13 factors compared between the two stocks.

How does Actuate Therapeutics compare to Hillstream Biopharma?

Actuate Therapeutics (NASDAQ:ACTU) and Hillstream Biopharma (NASDAQ:CNTN) are both small-cap pharmaceutical products companies, but which is the superior stock? We will compare the two businesses based on the strength of their analyst recommendations, institutional ownership, dividends, risk, valuation, profitability, earnings and media sentiment.

Actuate Therapeutics currently has a consensus target price of $17.50, indicating a potential upside of 766.34%. Given Actuate Therapeutics' stronger consensus rating and higher probable upside, research analysts clearly believe Actuate Therapeutics is more favorable than Hillstream Biopharma.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Actuate Therapeutics
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33
Hillstream Biopharma
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00

In the previous week, Actuate Therapeutics had 2 more articles in the media than Hillstream Biopharma. MarketBeat recorded 3 mentions for Actuate Therapeutics and 1 mentions for Hillstream Biopharma. Hillstream Biopharma's average media sentiment score of 1.89 beat Actuate Therapeutics' score of 0.62 indicating that Hillstream Biopharma is being referred to more favorably in the news media.

Company Overall Sentiment
Actuate Therapeutics Positive
Hillstream Biopharma Very Positive

Actuate Therapeutics has a beta of 0.53, suggesting that its stock price is 47% less volatile than the broader market. Comparatively, Hillstream Biopharma has a beta of 1.41, suggesting that its stock price is 41% more volatile than the broader market.

1.2% of Hillstream Biopharma shares are owned by institutional investors. 58.0% of Actuate Therapeutics shares are owned by company insiders. Comparatively, 6.7% of Hillstream Biopharma shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Hillstream Biopharma's return on equity of -31.50% beat Actuate Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Actuate TherapeuticsN/A -430.93% -180.86%
Hillstream Biopharma N/A -31.50%-24.72%

Hillstream Biopharma is trading at a lower price-to-earnings ratio than Actuate Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Actuate TherapeuticsN/AN/A-$22.23M-$0.97N/A
Hillstream BiopharmaN/AN/A-$35.92M-$1.15N/A

Summary

Actuate Therapeutics beats Hillstream Biopharma on 8 of the 13 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding ACTU and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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ACTU vs. The Competition

MetricActuate TherapeuticsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$48.34M$3.39B$6.52B$12.05B
Dividend YieldN/A2.25%2.67%5.66%
P/E Ratio-2.0820.0024.0024.42
Price / SalesN/A303.75533.77123.88
Price / CashN/A53.6127.4837.92
Price / Book5.948.3210.556.82
Net Income-$22.23M$23.94M$3.57B$337.56M
7 Day Performance10.99%1.84%0.59%1.16%
1 Month Performance-22.90%-0.04%1.55%3.16%
1 Year Performance-76.65%44.82%25.41%30.60%

Actuate Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
ACTU
Actuate Therapeutics
2.0528 of 5 stars
$2.02
flat
$17.50
+766.3%
-76.6%$48.34MN/AN/A10
ARTV
Artiva Biotherapeutics
3.869 of 5 stars
$7.05
+2.6%
$39.00
+453.2%
+331.3%$174.28M$250KN/A81
OKUR
OnKure Therapeutics
2.7652 of 5 stars
$4.31
+2.1%
$27.00
+526.5%
+58.5%$174.12MN/AN/AN/A
IPHA
Innate Pharma
3.2999 of 5 stars
$1.81
-0.5%
$5.00
+176.2%
-7.1%$170.00M$10.19MN/A220
ABOS
Acumen Pharmaceuticals
2.5217 of 5 stars
$2.33
-1.7%
$6.67
+186.1%
+121.5%$168.29MN/AN/A20

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This page (NASDAQ:ACTU) was last updated on 6/15/2026 by MarketBeat.com Staff.
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