Actuate Therapeutics (ACTU) Competitors

$2.38 0.00 (0.00%)

Closing price 05/22/2026 04:00 PM Eastern

Extended Trading

$2.40 +0.02 (+1.05%)

As of 05/22/2026 06:40 PM Eastern

ACTU vs. EDIT, AVXL, ACIU, ALXO, and CHRS

Should you buy Actuate Therapeutics stock or one of its competitors? MarketBeat compares Actuate Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Actuate Therapeutics include Editas Medicine (EDIT), Anavex Life Sciences (AVXL), AC Immune (ACIU), ALX Oncology (ALXO), and Coherus Oncology (CHRS). These companies are all part of the "pharmaceutical products" industry.

How does Actuate Therapeutics compare to Editas Medicine?

Editas Medicine (NASDAQ:EDIT) and Actuate Therapeutics (NASDAQ:ACTU) are both small-cap medical companies, but which is the superior investment? We will contrast the two businesses based on the strength of their earnings, institutional ownership, profitability, media sentiment, valuation, risk, dividends and analyst recommendations.

Actuate Therapeutics has lower revenue, but higher earnings than Editas Medicine. Actuate Therapeutics is trading at a lower price-to-earnings ratio than Editas Medicine, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Editas Medicine	$40.52M	6.67	-$160.06M	-$1.23	N/A
Actuate Therapeutics	N/A	N/A	-$22.23M	-$0.97	N/A

In the previous week, Actuate Therapeutics had 16 more articles in the media than Editas Medicine. MarketBeat recorded 17 mentions for Actuate Therapeutics and 1 mentions for Editas Medicine. Editas Medicine's average media sentiment score of 0.00 beat Actuate Therapeutics' score of -0.26 indicating that Editas Medicine is being referred to more favorably in the media.

Company	Very Positive	Positive	Neutral	Negative	Very Negative	Overall Sentiment
Editas Medicine	0 Very Positive mention(s)	0 Positive mention(s)	1 Neutral mention(s)	0 Negative mention(s)	0 Very Negative mention(s)	Neutral
Actuate Therapeutics	0 Very Positive mention(s)	0 Positive mention(s)	3 Neutral mention(s)	2 Negative mention(s)	0 Very Negative mention(s)	Neutral

Editas Medicine currently has a consensus price target of $5.40, suggesting a potential upside of 95.65%. Actuate Therapeutics has a consensus price target of $17.50, suggesting a potential upside of 635.29%. Given Actuate Therapeutics' higher possible upside, analysts plainly believe Actuate Therapeutics is more favorable than Editas Medicine.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Editas Medicine	1 Sell rating(s)	1 Hold rating(s)	5 Buy rating(s)	0 Strong Buy rating(s)	2.57
Actuate Therapeutics	1 Sell rating(s)	0 Hold rating(s)	2 Buy rating(s)	0 Strong Buy rating(s)	2.33

Editas Medicine has a beta of 2.14, suggesting that its share price is 114% more volatile than the broader market. Comparatively, Actuate Therapeutics has a beta of 0.92, suggesting that its share price is 8% less volatile than the broader market.

71.9% of Editas Medicine shares are owned by institutional investors. 3.1% of Editas Medicine shares are owned by company insiders. Comparatively, 58.0% of Actuate Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

Actuate Therapeutics has a net margin of 0.00% compared to Editas Medicine's net margin of -281.59%. Actuate Therapeutics' return on equity of -430.93% beat Editas Medicine's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Editas Medicine	-281.59%	-677.39%	-58.25%
Actuate Therapeutics	N/A	-430.93%	-180.86%

Summary

Editas Medicine beats Actuate Therapeutics on 8 of the 15 factors compared between the two stocks.

How does Actuate Therapeutics compare to Anavex Life Sciences?

Actuate Therapeutics (NASDAQ:ACTU) and Anavex Life Sciences (NASDAQ:AVXL) are both small-cap medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their valuation, profitability, institutional ownership, media sentiment, earnings, risk, dividends and analyst recommendations.

31.6% of Anavex Life Sciences shares are held by institutional investors. 58.0% of Actuate Therapeutics shares are held by insiders. Comparatively, 11.4% of Anavex Life Sciences shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

Anavex Life Sciences' return on equity of -38.76% beat Actuate Therapeutics' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Actuate Therapeutics	N/A	-430.93%	-180.86%
Anavex Life Sciences	N/A	-38.76%	-35.01%

Actuate Therapeutics currently has a consensus target price of $17.50, suggesting a potential upside of 635.29%. Anavex Life Sciences has a consensus target price of $21.33, suggesting a potential upside of 693.06%. Given Anavex Life Sciences' stronger consensus rating and higher probable upside, analysts clearly believe Anavex Life Sciences is more favorable than Actuate Therapeutics.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Actuate Therapeutics	1 Sell rating(s)	0 Hold rating(s)	2 Buy rating(s)	0 Strong Buy rating(s)	2.33
Anavex Life Sciences	1 Sell rating(s)	1 Hold rating(s)	3 Buy rating(s)	0 Strong Buy rating(s)	2.40

Actuate Therapeutics has a beta of 0.92, indicating that its share price is 8% less volatile than the broader market. Comparatively, Anavex Life Sciences has a beta of 1.24, indicating that its share price is 24% more volatile than the broader market.

Anavex Life Sciences is trading at a lower price-to-earnings ratio than Actuate Therapeutics, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Actuate Therapeutics	N/A	N/A	-$22.23M	-$0.97	N/A
Anavex Life Sciences	N/A	N/A	-$46.38M	-$0.46	N/A

In the previous week, Actuate Therapeutics had 15 more articles in the media than Anavex Life Sciences. MarketBeat recorded 17 mentions for Actuate Therapeutics and 2 mentions for Anavex Life Sciences. Anavex Life Sciences' average media sentiment score of 0.96 beat Actuate Therapeutics' score of -0.26 indicating that Anavex Life Sciences is being referred to more favorably in the news media.

Company	Very Positive	Positive	Neutral	Negative	Very Negative	Overall Sentiment
Actuate Therapeutics	0 Very Positive mention(s)	0 Positive mention(s)	3 Neutral mention(s)	2 Negative mention(s)	0 Very Negative mention(s)	Neutral
Anavex Life Sciences	1 Very Positive mention(s)	0 Positive mention(s)	1 Neutral mention(s)	0 Negative mention(s)	0 Very Negative mention(s)	Positive

Summary

Anavex Life Sciences beats Actuate Therapeutics on 9 of the 13 factors compared between the two stocks.

How does Actuate Therapeutics compare to AC Immune?

Actuate Therapeutics (NASDAQ:ACTU) and AC Immune (NASDAQ:ACIU) are both small-cap medical companies, but which is the better stock? We will compare the two companies based on the strength of their dividends, valuation, analyst recommendations, profitability, risk, media sentiment, earnings and institutional ownership.

51.4% of AC Immune shares are owned by institutional investors. 58.0% of Actuate Therapeutics shares are owned by insiders. Comparatively, 4.6% of AC Immune shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Actuate Therapeutics currently has a consensus price target of $17.50, indicating a potential upside of 635.29%. AC Immune has a consensus price target of $7.50, indicating a potential upside of 165.02%. Given Actuate Therapeutics' stronger consensus rating and higher probable upside, equities research analysts clearly believe Actuate Therapeutics is more favorable than AC Immune.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Actuate Therapeutics	1 Sell rating(s)	0 Hold rating(s)	2 Buy rating(s)	0 Strong Buy rating(s)	2.33
AC Immune	1 Sell rating(s)	1 Hold rating(s)	2 Buy rating(s)	0 Strong Buy rating(s)	2.25

Actuate Therapeutics has a beta of 0.92, indicating that its stock price is 8% less volatile than the broader market. Comparatively, AC Immune has a beta of 1.65, indicating that its stock price is 65% more volatile than the broader market.

Actuate Therapeutics has a net margin of 0.00% compared to AC Immune's net margin of -1,788.02%. AC Immune's return on equity of -125.26% beat Actuate Therapeutics' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Actuate Therapeutics	N/A	-430.93%	-180.86%
AC Immune	-1,788.02%	-125.26%	-40.85%

In the previous week, Actuate Therapeutics had 14 more articles in the media than AC Immune. MarketBeat recorded 17 mentions for Actuate Therapeutics and 3 mentions for AC Immune. AC Immune's average media sentiment score of 0.92 beat Actuate Therapeutics' score of -0.26 indicating that AC Immune is being referred to more favorably in the news media.

Company	Very Positive	Positive	Neutral	Negative	Very Negative	Overall Sentiment
Actuate Therapeutics	0 Very Positive mention(s)	0 Positive mention(s)	3 Neutral mention(s)	2 Negative mention(s)	0 Very Negative mention(s)	Neutral
AC Immune	2 Very Positive mention(s)	0 Positive mention(s)	1 Neutral mention(s)	0 Negative mention(s)	0 Very Negative mention(s)	Positive

Actuate Therapeutics has higher earnings, but lower revenue than AC Immune. AC Immune is trading at a lower price-to-earnings ratio than Actuate Therapeutics, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Actuate Therapeutics	N/A	N/A	-$22.23M	-$0.97	N/A
AC Immune	$4.31M	66.82	-$85.03M	-$0.82	N/A

Summary

Actuate Therapeutics and AC Immune tied by winning 7 of the 14 factors compared between the two stocks.

How does Actuate Therapeutics compare to ALX Oncology?

ALX Oncology (NASDAQ:ALXO) and Actuate Therapeutics (NASDAQ:ACTU) are both small-cap medical companies, but which is the better investment? We will compare the two businesses based on the strength of their risk, valuation, institutional ownership, analyst recommendations, earnings, profitability, media sentiment and dividends.

98.0% of ALX Oncology shares are held by institutional investors. 21.0% of ALX Oncology shares are held by insiders. Comparatively, 58.0% of Actuate Therapeutics shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

ALX Oncology has a beta of 0.41, meaning that its stock price is 59% less volatile than the broader market. Comparatively, Actuate Therapeutics has a beta of 0.92, meaning that its stock price is 8% less volatile than the broader market.

Actuate Therapeutics is trading at a lower price-to-earnings ratio than ALX Oncology, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
ALX Oncology	N/A	N/A	-$101.69M	-$1.49	N/A
Actuate Therapeutics	N/A	N/A	-$22.23M	-$0.97	N/A

ALX Oncology's return on equity of -124.06% beat Actuate Therapeutics' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
ALX Oncology	N/A	-124.06%	-85.57%
Actuate Therapeutics	N/A	-430.93%	-180.86%

In the previous week, Actuate Therapeutics had 17 more articles in the media than ALX Oncology. MarketBeat recorded 17 mentions for Actuate Therapeutics and 0 mentions for ALX Oncology. ALX Oncology's average media sentiment score of 0.00 beat Actuate Therapeutics' score of -0.26 indicating that ALX Oncology is being referred to more favorably in the media.

Company	Overall Sentiment
ALX Oncology	Neutral
Actuate Therapeutics	Neutral

ALX Oncology presently has a consensus target price of $4.60, suggesting a potential upside of 132.32%. Actuate Therapeutics has a consensus target price of $17.50, suggesting a potential upside of 635.29%. Given Actuate Therapeutics' higher possible upside, analysts clearly believe Actuate Therapeutics is more favorable than ALX Oncology.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
ALX Oncology	1 Sell rating(s)	0 Hold rating(s)	5 Buy rating(s)	0 Strong Buy rating(s)	2.67
Actuate Therapeutics	1 Sell rating(s)	0 Hold rating(s)	2 Buy rating(s)	0 Strong Buy rating(s)	2.33

Summary

ALX Oncology beats Actuate Therapeutics on 7 of the 13 factors compared between the two stocks.

How does Actuate Therapeutics compare to Coherus Oncology?

Actuate Therapeutics (NASDAQ:ACTU) and Coherus Oncology (NASDAQ:CHRS) are both small-cap medical companies, but which is the better investment? We will compare the two businesses based on the strength of their dividends, risk, earnings, profitability, institutional ownership, valuation, media sentiment and analyst recommendations.

Actuate Therapeutics has a beta of 0.92, suggesting that its stock price is 8% less volatile than the broader market. Comparatively, Coherus Oncology has a beta of 1.01, suggesting that its stock price is 1% more volatile than the broader market.

72.8% of Coherus Oncology shares are owned by institutional investors. 58.0% of Actuate Therapeutics shares are owned by insiders. Comparatively, 8.1% of Coherus Oncology shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

Coherus Oncology has higher revenue and earnings than Actuate Therapeutics. Actuate Therapeutics is trading at a lower price-to-earnings ratio than Coherus Oncology, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Actuate Therapeutics	N/A	N/A	-$22.23M	-$0.97	N/A
Coherus Oncology	$42.17M	5.89	$168.02M	$1.67	0.96

Coherus Oncology has a net margin of 397.30% compared to Actuate Therapeutics' net margin of 0.00%. Coherus Oncology's return on equity of -198.90% beat Actuate Therapeutics' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Actuate Therapeutics	N/A	-430.93%	-180.86%
Coherus Oncology	397.30%	-198.90%	-46.65%

Actuate Therapeutics currently has a consensus price target of $17.50, suggesting a potential upside of 635.29%. Coherus Oncology has a consensus price target of $8.67, suggesting a potential upside of 438.30%. Given Actuate Therapeutics' higher probable upside, equities research analysts clearly believe Actuate Therapeutics is more favorable than Coherus Oncology.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Actuate Therapeutics	1 Sell rating(s)	0 Hold rating(s)	2 Buy rating(s)	0 Strong Buy rating(s)	2.33
Coherus Oncology	0 Sell rating(s)	1 Hold rating(s)	3 Buy rating(s)	0 Strong Buy rating(s)	2.75

In the previous week, Actuate Therapeutics had 17 more articles in the media than Coherus Oncology. MarketBeat recorded 17 mentions for Actuate Therapeutics and 0 mentions for Coherus Oncology. Coherus Oncology's average media sentiment score of 0.00 beat Actuate Therapeutics' score of -0.26 indicating that Coherus Oncology is being referred to more favorably in the news media.

Company	Overall Sentiment
Actuate Therapeutics	Neutral
Coherus Oncology	Neutral

Summary

Coherus Oncology beats Actuate Therapeutics on 12 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding ACTU and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.

Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.

ACTU vs. The Competition

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Metric	Actuate Therapeutics	MED Industry	Medical Sector	NASDAQ Exchange
Market Cap	$56.94M	$3.37B	$6.46B	$12.34B
Dividend Yield	N/A	2.26%	2.76%	5.28%
P/E Ratio	-2.45	18.74	21.22	25.66
Price / Sales	N/A	323.98	562.28	86.31
Price / Cash	N/A	125.17	43.49	56.67
Price / Book	14.88	7.09	10.31	7.14
Net Income	-$22.23M	$24.45M	$3.57B	$335.98M
7 Day Performance	-0.83%	6.38%	6.43%	4.15%
1 Month Performance	-19.87%	2.43%	3.57%	2.54%
1 Year Performance	-76.96%	62.98%	34.07%	35.06%

Actuate Therapeutics Competitors List

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Company	MarketRank	Share Price	Analysts' Price Target	1Y Price Performance	Market Cap	Revenue	P/E Ratio	Employee Count	Indicator(s)
ACTU Actuate Therapeutics	2.1902 of 5 stars	$2.38 flat	$17.50 +635.3%	-77.0%	$56.94M	N/A	N/A	10	Analyst Downgrade Gap Up
EDIT Editas Medicine	2.8571 of 5 stars	$2.89 -1.5%	$5.40 +87.2%	+78.1%	$282.47M	$40.52M	N/A	230	Gap Down
AVXL Anavex Life Sciences	2.0546 of 5 stars	$3.06 -0.2%	$21.33 +598.3%	-64.3%	$282.18M	N/A	N/A	40
ACIU AC Immune	2.649 of 5 stars	$2.77 flat	$7.50 +170.8%	+67.5%	$281.90M	$4.31M	N/A	140
ALXO ALX Oncology	2.7153 of 5 stars	$2.08 +2.2%	$4.60 +121.7%	+327.0%	$279.21M	N/A	N/A	40

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This page (NASDAQ:ACTU) was last updated on 5/26/2026 by MarketBeat.com Staff.

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Actuate Therapeutics (ACTU) Competitors

ACTU vs. EDIT, AVXL, ACIU, ALXO, and CHRS

How does Actuate Therapeutics compare to Editas Medicine?

Summary

How does Actuate Therapeutics compare to Anavex Life Sciences?

Summary

How does Actuate Therapeutics compare to AC Immune?

Summary

How does Actuate Therapeutics compare to ALX Oncology?

Summary

How does Actuate Therapeutics compare to Coherus Oncology?

Summary

New MarketBeat Followers Over Time

Media Sentiment Over Time

ACTU vs. The Competition

Actuate Therapeutics Competitors List

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Actuate Therapeutics (ACTU) Competitors

ACTU vs. EDIT, AVXL, ACIU, ALXO, and CHRS

How does Actuate Therapeutics compare to Editas Medicine?

Which has stronger valuation and earnings, EDIT or ACTU?

Does the media favor EDIT or ACTU?

Do analysts recommend EDIT or ACTU?

Which has more volatility and risk, EDIT or ACTU?

Do institutionals and insiders hold more shares of EDIT or ACTU?

Is EDIT or ACTU more profitable?

Summary

How does Actuate Therapeutics compare to Anavex Life Sciences?

Do insiders and institutionals hold more shares of ACTU or AVXL?

Is ACTU or AVXL more profitable?

Do analysts prefer ACTU or AVXL?

Which has more risk and volatility, ACTU or AVXL?

Which has higher valuation and earnings, ACTU or AVXL?

Does the media refer more to ACTU or AVXL?

Summary

How does Actuate Therapeutics compare to AC Immune?

Do insiders & institutionals have more ownership in ACTU or ACIU?

Do analysts rate ACTU or ACIU?

Which has more risk & volatility, ACTU or ACIU?

Is ACTU or ACIU more profitable?

Does the media prefer ACTU or ACIU?

Which has stronger earnings and valuation, ACTU or ACIU?

Summary

How does Actuate Therapeutics compare to ALX Oncology?

Do insiders and institutionals hold more shares of ALXO or ACTU?

Which has more volatility & risk, ALXO or ACTU?

Which has higher earnings & valuation, ALXO or ACTU?

Is ALXO or ACTU more profitable?

Does the media favor ALXO or ACTU?

Do analysts rate ALXO or ACTU?

Summary

How does Actuate Therapeutics compare to Coherus Oncology?

Which has more risk & volatility, ACTU or CHRS?

Do institutionals & insiders hold more shares of ACTU or CHRS?

Which has stronger earnings & valuation, ACTU or CHRS?

Is ACTU or CHRS more profitable?

Do analysts recommend ACTU or CHRS?

Does the media refer more to ACTU or CHRS?

Summary

New MarketBeat Followers Over Time

Media Sentiment Over Time

ACTU vs. The Competition

Actuate Therapeutics Competitors List

Related Companies and Tools

MarketBeat All Access Features

Best-in-Class Portfolio Monitoring

Stock Ideas and Recommendations

Advanced Stock Screeners and Research Tools