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Is Pfizer Stock Still Worth Buying After the Pandemic?

Is Pfizer Stock Still Worth Buying After the Pandemic? Literally synonymous with COVID-19 vaccines, pharmaceutical giant Pfizer Inc. NYSE: PFE has delivered over 367 million vaccinations in the U.S. alone and over 1.4 billion does worldwide since the pandemic began.

Moderna Inc. NASDAQ: MRNA comes in a distant second place with over 230 million vaccinations. Johnson & Johnson NYSE: JNJ comes in a telescopic third place with a distribution of just over 2.5 million COVID-19 vaccinations. Novavax Inc. NASDAQ: NVAX administered just over 30,000 vaccinations in the U.S. There’s no disputing that the pandemic has been a boon to Pfizer’s top and bottom lines and helped it expand its mRNA technology. The U.S. Department of Health and Human Services (HHS) stated in a report released October 6 that vaccinations were responsible for preventing over 600,000 hospitalizations and 300,000 deaths among Medicare patients. However, as the pandemic becomes less of a focus, investors wonder if Pfizer stock's good times will also follow suit.

Bustling COVID-19 Franchise

Key Points

  • Pfizer has a robust pipeline of over 90 drugs and vaccinations make up 38% of total revenues.
  • The company reported its highest quarterly sales in history in Q2 2022.
  • Pfizer appears to be recession-resistant due to COVID-19 vaccine government purchases.
  • 5 stocks we like better than Pfizer

Pfizer and its partner BioNTech NASDAQ: BNTX have turned COVID vaccinations into an evergreen franchise business with its booster shots — only 4% of eligible people are fully boosted. While some investors may see this as a glass-half-full situation and believe 96% more booster vaccinations will unleash, the general population may be getting complacent. More individuals drop off with each round of booster shots, which naturally hurts Pfizer’s bottom line. 

Paxlovid Drives Growth

Pfizer continues to develop COVID-19 therapies for the COVID franchise, including Paxlovid, an oral pill that fights the virus by preventing it from replicating in the body. It’s a three-pill antiviral regimen for people who contract COVID-19 and treats those in higher-risk categories (the elderly, diabetics, heart and kidney disease and cancer patients). It has been proven 89% effective in cutting hospitalizations and death compared to a placebo group. President Joe Biden was the most high-profile candidate to use the drug. Some patients, like Biden, experience “Paxlovid rebound,” where he tested positive for COVID-19 again, but without symptoms. This occurs in 1% to 2% of patients but outcomes are still positive.

The company expects Paxlovid to generate $22 billion and Comirnaty (a COVID-19 vaccine for immunization) to generate $32 billion over last months of 2022. Pfizer inked a $3.2 billion deal with the U.S. government for the fall vaccination campaign.

Expanding mRNA

Pfizer and BioNTech have expanded the applications for its mRNA vaccines to include influenza (flu) and shingles. The global influenza market is estimated to exceed $10 billion by 2030. Pfizer has already formed a 25,000-subject test group for its third phase quadrivalent mRNA vaccine for the flu. Its expanded Acuitas Therapeutics lipid nanoparticles (LNP) licensing enables Pfizer to target vaccines for 10 other indications. It also acquired Biohaven Pharmaceuticals for $3.5 billion to gain its migraine drug Nurtec ODT and zavegepant.

Pfizer has a robust pipeline of over 90 drugs in development and 12 pivotal readouts for 2022. Two drugs with billion-dollar potential in phase three include its Duchenne syndrome (250,000 patients globally) and respiratory syncytial virus ($4 billion market by 2027). However, competitors Sarepta NASDAQ: SRPT and GlaxoSmithKline NYSE: GSK are both further ahead in development. 

Is Pfizer Stock Still Worth Buying After the Pandemic?

PFE Opportunistic Pullback Levels

Using the rifle charts on the weekly and daily timeframes provides a precision view of the landscape for PFE stock. The weekly rifle chart has been in a sharp downtrend led by the five-period moving average (MA) resistance at $44.81, followed by the 15-period MA resistance at $48.27 and falling through the weekly market structure low (MSL) buy at $43.83. The weekly 200-period MA support sits near the $40.99 Fibonacci (fib) level. The weekly 200-period MA support lies at $40.82 and weekly lower Bollinger Bands (BBs) at $40.24. The weekly stochastic formed a bearish mini inverse pup that dropped it through the 10-band. The daily rifle chart formed an inverse pup breakdown with a falling five-period MA resistance at $43.63 followed by the daily 15-period MA at $44.08. The daily lower BBs sit at $41.46. Attractive pullback levels sit at the $40.99 and weekly 200-period MA, $39.50 fib, $38.57 fib, $35.93 fib, $34.52 fib, $32.79 fib and the $30.36 fib level.

Earnings Still Blowing Up

On July 28, Pfizer released its fiscal Q2 results for the quarter ending June 2022. The company reported an earnings per share (EPS) profit of $2.04 versus $1.78 consensus analyst estimates, a $0.26 beat. The company saw revenues grow 46.8% year-over-year (YoY) to $27.74 billion, driven by Paxlovid and Comirnaty and beating analyst estimates for $26.2 billion.

Raised Lowered Guidance for 2022

Pfizer has raised the lower end of its earlier lowered full-year 2022 estimates by $0.05 for EPS coming in between $6.30 to $6.45 versus $6.67 consensus analyst estimates. Full-year 2022 revenues should come in between $98 billion to $102 billion versus $103.62 billion per consensus analyst estimates. Based on supply contracts, the company expected $32 billion in sales for Comirnaty and $22 billion in revenues for Paxlovid.

Should you invest $1,000 in Pfizer right now?

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Companies Mentioned in This Article

CompanyMarketRank™Current PricePrice ChangeDividend YieldP/E RatioConsensus RatingConsensus Price Target
Pfizer (PFE)
4.8374 of 5 stars
BioNTech (BNTX)
1.5666 of 5 stars
Moderna (MRNA)
3.3497 of 5 stars
Johnson & Johnson (JNJ)
4.8479 of 5 stars
Novavax (NVAX)
3.9155 of 5 stars
Sarepta Therapeutics (SRPT)
4.7483 of 5 stars
$113.33-8.2%N/A1,030.27Moderate Buy$164.47
2.1524 of 5 stars
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Jea Yu

About Jea Yu


Contributing Author

Trading Strategies


Jea Yu has been a contributing writer for MarketBeat since 2018.

Areas of Expertise

Equities, options, ETFs and futures; fundamental, qualitative, quantitative and technical analysis and pattern identification; active and swing trading; trading systems and methodology development


Bachelor of Arts, University of Maryland, College Park

Past Experience

U.S. equity markets trader, writer and analyst for over 25 years. Published four books by publishers McGraw-Hill, John Wiley & Sons, Marketplace Books and Bloomberg Press. Speaker at various expos and seminars and has been quoted and featured in USA Today, The Wall Street Journal, Traders Magazine, The Financial Times and various trade publications, including Stocks & Commodities, Active Trader and Online Investor.

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