NASDAQ:ABOS Acumen Pharmaceuticals (ABOS) Stock Price, News & Analysis $2.51 0.00 (0.00%) Closing price 05/22/2026 04:00 PM EasternExtended Trading$2.50 0.00 (-0.20%) As of 05/22/2026 06:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock About Acumen Pharmaceuticals Stock (NASDAQ:ABOS) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Acumen Pharmaceuticals alerts:Sign Up Key Stats Today's Range$2.48▼$2.6050-Day Range$2.17▼$3.3452-Week Range$0.99▼$3.60Volume396,206 shsAverage Volume316,977 shsMarket Capitalization$181.29 millionP/E RatioN/ADividend YieldN/APrice Target$6.67Consensus RatingModerate Buy Company Overview Acumen Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on the discovery and development of oral small molecule therapies for neurodegenerative diseases. Leveraging a proprietary drug discovery platform that integrates chemoproteomics, high-throughput screening and computational chemistry, the company seeks to identify and optimize compounds that selectively modulate pathological protein aggregation. Its approach is designed to address the underlying biology of conditions such as Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis and related proteinopathies. The company’s pipeline comprises multiple lead candidates at various stages of preclinical and early clinical development. Its most advanced program targets abnormal tau aggregation in Alzheimer’s disease and has entered Phase 1 clinical testing. Additional preclinical candidates are designed to inhibit the misfolding or aggregation of proteins including TDP-43, alpha-synuclein, mutant huntingtin and transthyretin, with the goal of expanding its portfolio across a spectrum of neurodegenerative indications. Founded in 2019 and headquartered in San Diego, California, Acumen Pharmaceuticals has assembled a management team with extensive experience in small molecule drug discovery and neuroscience R&D. The company completed its initial public offering in mid-2023, raising capital to advance its lead program through clinical proof-of-concept and to prepare select preclinical candidates for first-in-human studies. Acumen’s research and development efforts are complemented by collaborations with academic laboratories and contract research organizations across North America. With a strategic focus on oral therapies that can be broadly administered in outpatient settings, Acumen aims to address significant unmet medical needs in the rapidly growing field of neurodegenerative disease treatment. The company’s leadership emphasizes rigorous translational science and biomarker-driven clinical development to accelerate the pathway from discovery to potential regulatory approval, ultimately seeking to improve quality of life for patients worldwide.AI Generated. May Contain Errors. Read More Acumen Pharmaceuticals Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks45th Percentile Overall ScoreABOS MarketRank™: Acumen Pharmaceuticals scored higher than 45% of companies evaluated by MarketBeat, and ranked 586th out of 869 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion3.7 / 5Analyst RatingModerate Buy Consensus RatingAcumen Pharmaceuticals has received a consensus rating of Moderate Buy. The company's average rating score is 2.50, and is based on no strong buy ratings, 3 buy ratings, no hold ratings, and 1 sell rating.Upside PotentialAcumen Pharmaceuticals has a consensus price target of $6.67, representing about 165.6% upside from its current price of $2.51.Amount of Analyst CoverageAcumen Pharmaceuticals has only been the subject of 2 research reports in the past 90 days.Read more about Acumen Pharmaceuticals' stock forecast and price target. Earnings and Valuation0.0 / 5Proj. Earnings GrowthDecreasing Earnings GrowthEarnings for Acumen Pharmaceuticals are expected to decrease in the coming year, from ($1.43) to ($2.38) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Acumen Pharmaceuticals is -1.35, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Acumen Pharmaceuticals is -1.35, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioAcumen Pharmaceuticals has a P/B Ratio of 2.07. P/B Ratios below 3 indicates that a company is reasonably valued with respect to its assets and liabilities.Read more about Acumen Pharmaceuticals' valuation and earnings. Short Interest2.0 / 5Short Interest LevelBearish Percentage of Shares Shorted2.50% of the float of Acumen Pharmaceuticals has been sold short.Short Interest Ratio / Days to CoverAcumen Pharmaceuticals has a short interest ratio ("days to cover") of 5.17.Change versus previous monthShort interest in Acumen Pharmaceuticals has recently increased by 8.47%, indicating that investor sentiment is decreasing significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldAcumen Pharmaceuticals does not currently pay a dividend.Dividend GrowthAcumen Pharmaceuticals does not have a long track record of dividend growth. News and Social Media2.7 / 5News Sentiment0.25 News SentimentAcumen Pharmaceuticals has a news sentiment score of 0.25. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.45 average news sentiment score of Medical companies.News Coverage This WeekMarketBeat has tracked 2 news articles for Acumen Pharmaceuticals this week, compared to 3 articles on an average week.Search Interest8 people have searched for ABOS on MarketBeat in the last 30 days. This is an increase of 167% compared to the previous 30 days.MarketBeat Follows3 people have added Acumen Pharmaceuticals to their MarketBeat watchlist in the last 30 days. This is an increase of 50% compared to the previous 30 days. Company Ownership1.0 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, Acumen Pharmaceuticals insiders have not sold or bought any company stock.Percentage Held by Insiders9.30% of the stock of Acumen Pharmaceuticals is held by insiders.Percentage Held by Institutions71.01% of the stock of Acumen Pharmaceuticals is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Acumen Pharmaceuticals' insider trading history. Receive ABOS Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Acumen Pharmaceuticals and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. ABOS Stock News HeadlinesAcumen's Late-2026 Sabirnetug Readout Is A Viable BetMay 20, 2026 | seekingalpha.comAcumen Pharma president Doherty sells $15k in ABOS stockMay 19, 2026 | investing.comYour book is insideThe "Sucker's Bet" Most New Options Traders Fall For Most people who try options lose money the same way. They don't know the rules. They don't know what to avoid. And they hand their account to Wall Street on a silver platter. Normally $29.97. Free today.May 25 at 1:00 AM | Profits Run (Ad)Acumen Pharmaceuticals Sets Sights on Key Alzheimer's Drug Readout This YearMay 16, 2026 | americanbankingnews.comAcumen Pharmaceuticals, Inc. (ABOS) Presents at Bank of America Global Healthcare Conference 2026 TranscriptMay 14, 2026 | seekingalpha.comAcumen Pharmaceuticals Warns Investors: Unchanged 10-K Risk Factors Still Weigh on Valuation and Share PriceMay 14, 2026 | tipranks.comAcumen Pharmaceuticals Bets Big on Alzheimer’s TrialsMay 12, 2026 | tipranks.comAcumen Pharmaceuticals Inc (ABOS) Q1 2026 Earnings Call Highlights: Strategic Advances Amid ...May 12, 2026 | finance.yahoo.comSee More Headlines ABOS Stock Analysis - Frequently Asked Questions How have ABOS shares performed this year? Acumen Pharmaceuticals' stock was trading at $2.11 at the start of the year. Since then, ABOS stock has increased by 19.0% and is now trading at $2.51. How were Acumen Pharmaceuticals' earnings last quarter? Acumen Pharmaceuticals, Inc. (NASDAQ:ABOS) announced its quarterly earnings data on Tuesday, May, 12th. The company reported ($0.33) earnings per share (EPS) for the quarter, beating analysts' consensus estimates of ($0.40) by $0.07. Read the conference call transcript. When did Acumen Pharmaceuticals IPO? Acumen Pharmaceuticals (ABOS) raised $150 million in an initial public offering (IPO) on Tuesday, June 29th 2021. The company issued 9,999,999 shares at $14.00-$16.00 per share. Who are Acumen Pharmaceuticals' major shareholders? Top institutional shareholders of Acumen Pharmaceuticals include ADAR1 Capital Management LLC (2.99%), SG Americas Securities LLC (1.00%), Renaissance Technologies LLC (0.66%) and Bank of America Corp DE (0.44%). Insiders that own company stock include Ra Capital Management, LP, Daniel Joseph Oconnell, Matt Zuga, Eric Siemers, Russell Barton, Derek M Meisner, James J Doherty and Jeffrey L Ives. View institutional ownership trends. How do I buy shares of Acumen Pharmaceuticals? Shares of ABOS stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Acumen Pharmaceuticals own? Based on aggregate information from My MarketBeat watchlists, some other companies that Acumen Pharmaceuticals investors own include Invesco QQQ (QQQ), SPDR S&P 500 ETF Trust (SPY), SPDR Dow Jones Industrial Average ETF Trust (DIA), Tesla (TSLA), Meta Platforms (META), NVIDIA (NVDA) and Netflix (NFLX). Company Calendar Last Earnings5/12/2026Today5/25/2026Next Earnings (Estimated)8/11/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Green Zone (10m+) 1-Year History May 25 Aug 25 Nov 25 Feb 26 May 26 ABOS's financial health is in the Green zone, according to TradeSmith. ABOS has been in this zone for over 10 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry MED - BIOMED/GENE Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:ABOS CIK1576885 Webwww.acumenpharm.com Phone434-297-1000FaxN/AEmployees20Year Founded1996Price Target and Rating Average Price Target for Acumen Pharmaceuticals$6.67 High Price Target$8.00 Low Price Target$4.00 Potential Upside/Downside+165.6%Consensus RatingModerate Buy Rating Score (0-4)2.50 Research Coverage4 Analysts Profitability EPS (Trailing Twelve Months)($1.86) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$121.33 million Net MarginsN/A Pretax MarginN/A Return on Equity-123.07% Return on Assets-79.41% Debt Debt-to-Equity Ratio0.19 Current Ratio4.55 Quick Ratio4.55 Sales & Book Value Annual SalesN/A Price / SalesN/A Cash FlowN/A Price / Cash FlowN/A Book Value$1.21 per share Price / Book2.07Miscellaneous Outstanding Shares72,228,000Free Float65,511,000Market Cap$181.29 million OptionableOptionable Beta0.32 Social Links The 10 Best High-Yield Dividend Stocks for 2026Discover the 10 Best High-Yield Dividend Stocks for 2026 and secure reliable income in uncertain markets. Download the report now to identify top dividend payers and avoid common yield traps.Get This Free Report This page (NASDAQ:ABOS) was last updated on 5/25/2026 by MarketBeat.com Staff. 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