Adagene (ADAG) Stock Price, News & Analysis

Company Overview

Adagene Inc., headquartered in Suzhou, China, is a clinical-stage biopharmaceutical company specializing in the discovery and development of antibody-based therapeutics for cancer and immune-related diseases. Founded in 2017, the company leverages its proprietary immunome technology platform to mine human antibody repertoires and engineer novel monospecific and bispecific antibodies. Adagene’s pipeline includes multiple candidates in preclinical and early clinical development, with a focus on targeting tumor microenvironments and modulating immune checkpoints to enhance anti-tumor efficacy.

At the core of Adagene’s research and development efforts is its Bihanc™ antibody platform, which combines combinatorial phage display, structure-based design and artificial intelligence to optimize binding affinity, specificity and developability. The immunome platform enables rapid identification of high-quality antibody candidates derived from healthy donor B cells, while the AI-driven design engine accelerates selection and engineering, aiming to streamline candidate advancement toward investigational new drug filings and clinical trials.

Adagene operates research facilities in Suzhou and maintains an office in Cambridge, Massachusetts, serving global markets through strategic collaborations with leading pharmaceutical partners. The company’s leadership team is led by founder and CEO Dr. Ying Yan, whose expertise in antibody discovery and immuno-oncology has driven the development of its platform-based strategy. Under her guidance, Adagene has expanded its research capabilities and advanced multiple therapeutic candidates into the clinic.

Key Stats

• Today's Range: $1.76 to $1.85
• 50-Day Range: $1.65 to $2.50
• 52-Week Range: $1.33 to $3.16
• Volume: 25,824 shs
• Average Volume: 81,092 shs
• Market Capitalization: $82.95 million
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $7.00
• Consensus Rating: Moderate Buy

Adagene Stock Analysis - MarketRank™

Adagene scored higher than 43% of companies evaluated by MarketBeat, and ranked 649th out of 950 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 4.1 / 5
• Analyst Rating: Moderate Buy

Consensus Rating

Adagene has received a consensus rating of Moderate Buy. The company's average rating score is 2.60, and is based on 2 buy ratings, 1 hold rating, and 1 sell rating.

Upside Potential

Adagene has a consensus price target of $7.00, representing about 297.7% upside from its current price of $1.76.

Amount of Analyst Coverage

Adagene has only been the subject of 4 research reports in the past 90 days.

Earnings and Valuation

• Score: 0.0 / 5
• Proj. Earnings Growth: Decreasing

Earnings Growth

Earnings for Adagene are expected to decrease in the coming year, from ($0.60) to ($0.76) per share.

Price to Book Value per Share Ratio

Adagene has a P/B Ratio of 1.54. P/B Ratios below 3 indicates that a company is reasonably valued with respect to its assets and liabilities.

Short Interest

• Score: 3.0 / 5
• Short Interest Level: Healthy

Percentage of Shares Shorted

0.20% of the float of Adagene has been sold short.

Short Interest Ratio / Days to Cover

Adagene has a short interest ratio ("days to cover") of 0.7, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in Adagene has recently increased by 66.36%, indicating that investor sentiment is decreasing significantly.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

Adagene does not currently pay a dividend.

Dividend Growth

Adagene does not have a long track record of dividend growth.

Sustainability and ESG

• Score: N/A
• Environmental Score: N/A

Percentage of Shares Shorted

0.20% of the float of Adagene has been sold short.

Short Interest Ratio / Days to Cover

Adagene has a short interest ratio ("days to cover") of 0.7, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in Adagene has recently increased by 66.36%, indicating that investor sentiment is decreasing significantly.

News and Social Media

• Score: 0.6 / 5
• News Sentiment: N/A

News Sentiment

Adagene has a news sentiment score of -1.00. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.48 average news sentiment score of Medical companies.

News Coverage This Week

MarketBeat has tracked 1 news article for Adagene this week, compared to 2 articles on an average week.

Company Ownership

• Score: 1.7 / 5
• Insider Trading: N/A

Insider Buying vs. Insider Selling

In the past three months, Adagene insiders have not sold or bought any company stock.

Percentage Held by Insiders

21.20% of the stock of Adagene is held by insiders. A high percentage of insider ownership can be a sign of company health.

Percentage Held by Institutions

Only 9.51% of the stock of Adagene is held by institutions.

ADAG Stock Analysis - Frequently Asked Questions

How have ADAG shares performed this year?

Adagene's stock was trading at $1.99 at the beginning of 2025. Since then, ADAG shares have decreased by 11.6% and is now trading at $1.76.

When did Adagene IPO?

Adagene (ADAG) raised $133 million in an IPO on Tuesday, February 9th 2021. The company issued 7,400,000 shares at a price of $17.00-$19.00 per share. Goldman Sachs (Asia), Morgan Stanley and Jefferies served as the underwriters for the IPO and China Renaissance was co-manager.

How do I buy shares of Adagene?

Shares of ADAG stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of Adagene own?

Based on aggregate information from My MarketBeat watchlists, some other companies that Adagene investors own include NVIDIA (NVDA), Meta Platforms (META), Advanced Micro Devices (AMD), Arista Networks (ANET), Broadcom (AVGO), CrowdStrike (CRWD) and Adobe (ADBE).

Company Calendar

• Today: 10/19/2025
• Fiscal Year End: 12/31/2025

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Medical
• Industry: MED - BIOMED/GENE
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NASDAQ:ADAG
• CIK: 1818838
• Web: www.adagene.com
• Phone: 86-512-8777-3632
• Fax: N/A
• Employees: 260
• Year Founded: 2012

Price Target and Rating

• Average Price Target for Adagene: $7.00
• High Price Target: $7.00
• Low Price Target: $7.00
• Potential Upside/Downside: +297.7%
• Consensus Rating: Moderate Buy
• Rating Score (0-4): 2.60
• Research Coverage: 5 Analysts

Profitability

• EPS (Trailing Twelve Months): N/A
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: N/A
• Net Margins: N/A
• Pretax Margin: N/A
• Return on Equity: N/A
• Return on Assets: N/A

Debt

• Debt-to-Equity Ratio: N/A
• Current Ratio: 2.29
• Quick Ratio: N/A

Sales & Book Value

• Annual Sales: $100 thousand
• Price / Sales: 829.49
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: $1.14 per share
• Price / Book: 1.54

Miscellaneous

• Outstanding Shares: 47,130,000
• Free Float: 37,139,000
• Market Cap: $82.95 million
• Optionable: Not Optionable
• Beta: 0.74