CRISPR Therapeutics (CRSP) Short Interest Ratio & Short Volume $67.21 +0.69 (+1.04%) Closing price 10/23/2025 04:00 PM EasternExtended Trading$68.24 +1.03 (+1.53%) As of 08:32 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Short Interest Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock CRISPR Therapeutics Short Interest DataCRISPR Therapeutics (CRSP) has a short interest of 21.35 million shares. This marks a -10.33% decrease in short interest from the previous month. The short interest ratio (days to cover) is 7.4, indicating that it would take 7.4 days of the average trading volume of 2.76 million shares to cover all short positions.Current Short Interest21,350,000 sharesPrevious Short Interest23,810,000 sharesChange Vs. Previous Month-10.33%Dollar Volume Sold Short$1.38 billionShort Interest Ratio7.4 Days to CoverLast Record DateSeptember 30, 2025Outstanding Shares90,950,000 sharesPercentage of Shares Shorted23.47%Today's Trading Volume1,550,503 sharesAverage Trading Volume2,758,558 sharesToday's Volume Vs. Average56% Short Selling CRISPR Therapeutics? Sign up to receive the latest short interest report for CRISPR Therapeutics and its competitors with MarketBeat's FREE newsletter. 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Skip Charts & View Short Interest HistoryShort Interest ChartDays to Cover ChartShort Percent of Float ChartCRSP Short Interest Over TimeCRSP Days to Cover Over TimeCRSP Percentage of Float Shorted Over Time CRISPR Therapeutics Short Interest History Export to ExcelReport DateTotal Shares Sold ShortDollar Volume Sold ShortChange from Previous ReportPercentage of Float ShortedDays to CoverPrice on Report Date 9/30/202521,350,000 shares $1.38 billion -10.3%N/A7.4 $64.81 9/15/202523,810,000 shares $1.38 billion +7.9%N/A7.6 $57.84 8/31/202522,070,000 shares $1.14 billion -5.3%25.4%7 $51.83 8/15/202523,310,000 shares $1.39 billion -0.6%N/A7.2 $59.73 7/31/202523,450,000 shares $1.32 billion -7.3%26.9%7.5 $56.26 7/15/202525,300,000 shares $1.33 billion -0.9%N/A8.6 $52.73 6/30/202525,540,000 shares $1.24 billion +19.3%30.9%9.4 $48.64 6/15/202521,410,000 shares $885.52 million +4.2%25.9%9.3 $41.36 5/31/202520,540,000 shares $740.26 million -2.5%25.0%9.6 $36.04 5/15/202521,070,000 shares $765.05 million -1.2%25.6%10.5 $36.31 Get the Latest News and Ratings for CRSP and Related StocksEnter your email address below to receive the latest news and analysts' ratings for CRISPR Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 4/30/202521,320,000 shares $824.44 million +2.7%N/A9.4 $38.67 4/15/202520,760,000 shares $808.60 million +1.2%25.2%9.3 $38.95 3/31/202520,510,000 shares $697.96 million +1.0%24.9%9.2 $34.03 3/15/202520,310,000 shares $855.46 million -2.4%24.7%9.7 $42.12 2/28/202520,810,000 shares $913.98 million +2.0%25.3%9.7 $43.92 2/15/202520,410,000 shares $1.01 billion +4.7%24.8%9.5 $49.72 1/31/202519,490,000 shares $810.59 million -4.0%N/A10.1 $41.59 1/15/202520,310,000 shares $792.90 million +6.3%N/A10.8 $39.04 12/31/202419,100,000 shares $751.78 million +5.4%N/A11.4 $39.36 12/15/202418,120,000 shares $793.29 million -0.2%N/A11.6 $43.78 11/30/202418,150,000 shares $928.74 million -6.4%N/A12.7 $51.17 11/15/202419,390,000 shares $916.18 million +4.3%N/A14.8 $47.25 10/31/202418,590,000 shares $862.39 million +5.7%N/A16 $46.39 10/15/202417,590,000 shares $845.20 million +0.2%N/A16.1 $48.05 9/30/202417,560,000 shares $824.97 million +0.1%N/A14.9 $46.98 9/15/202417,540,000 shares $858.41 million +0.6%N/A14.7 $48.94 8/31/202417,440,000 shares $832.24 million +1.6%N/A13.8 $47.72 8/15/202417,170,000 shares $838.75 million +4.5%N/A13.1 $48.85 7/31/202416,430,000 shares $941.27 million +1.9%N/A12 $57.29 7/15/202416,120,000 shares $926.26 million +3.0%N/A12 $57.46 6/30/202415,650,000 shares $845.26 million +5.3%N/A11.9 $54.01 6/15/202414,870,000 shares $945.14 million -5.0%N/A11.1 $63.56 5/31/202415,660,000 shares $841.57 million +2.2%N/A12 $53.74 5/15/202415,330,000 shares $873.20 million +5.1%N/A10.9 $56.96 4/30/202414,590,000 shares $773.12 million -1.0%N/A8.5 $52.99 4/15/202414,740,000 shares $865.53 million -0.1%N/A8.5 $58.72 3/31/202414,760,000 shares $1.01 billion +0.3%N/A7.9 $68.16 3/15/202414,720,000 shares $1.07 billion -2.3%N/A7.4 $72.95 2/29/202415,060,000 shares $1.27 billion +1.3%N/A5.8 $84.22 2/15/202414,870,000 shares $1.26 billion -5.5%N/A5.5 $84.48 1/31/202415,740,000 shares $990.83 million -7.6%N/A5.6 $62.95 1/15/202417,040,000 shares $1.09 billion +4.9%N/A5.8 $64.25 12/31/202316,250,000 shares $1.02 billion -6.2%N/A5.9 $62.60 12/15/202317,330,000 shares $1.08 billion +8.8%N/A6.6 $62.08 11/30/202315,930,000 shares $1.06 billion -2.7%N/A7 $66.73 11/15/202316,370,000 shares $920.49 million +17.9%N/A9.6 $56.23 10/31/202313,890,000 shares $540.74 million +2.5%N/A10.9 $38.93 10/15/202313,550,000 shares $600.40 million +3.9%N/A13.3 $44.31 9/30/202313,040,000 shares $591.89 million -5.4%N/A13.4 $45.39 9/15/202313,790,000 shares $697.50 million -2.1%N/A14.6 $50.58 8/31/202314,080,000 shares $704.14 million +5.0%N/A13.7 $50.01 8/15/202313,410,000 shares $652.80 million +10.7%N/A11.9 $48.68 7/31/202312,110,000 shares $694.27 million -1.6%N/A9.5 $57.33 7/15/202312,310,000 shares $700.56 million -2.1%N/A9.8 $56.91 6/30/202312,570,000 shares $705.68 million +0.8%16.6%9.2 $56.14 6/15/202312,470,000 shares $734.98 million +2.3%16.5%9 $58.94 5/31/202312,190,000 shares $780.65 million -1.9%16.1%9.1 $64.04 5/15/202312,430,000 shares $819.76 million -5.8%16.4%9.5 $65.95 4/30/202313,200,000 shares $646.01 million +1.9%17.5%11.1 $48.94 4/15/202312,950,000 shares $651.51 million +2.0%17.2%11.3 $50.31 3/31/202312,700,000 shares $574.42 million +4.3%16.9%12.2 $45.23 3/15/202312,180,000 shares $547.13 million +9.0%16.2%11.3 $44.92 2/28/202311,170,000 shares $550.90 million +9.0%14.8%10 $49.32 2/15/202310,250,000 shares $534.74 million +2.7%13.7%9.4 $52.17 1/31/20239,980,000 shares $509.18 million +1.0%13.3%9.2 $51.02 1/15/20239,880,000 shares $493.41 million -5.7%13.2%9.1 $49.94 12/30/202210,480,000 shares $426.01 million +12.2%14.0%9.9 $40.65 12/15/20229,340,000 shares $443.65 million -16.2%12.4%8.8 $47.50 11/30/202211,140,000 shares $610.36 million -4.3%14.8%10.6 $54.79 11/15/202211,640,000 shares $710.16 million -7.3%15.5%10.8 $61.01 10/31/202212,550,000 shares $656.87 million +6.7%16.7%11.4 $52.34 10/15/202211,760,000 shares $635.86 million +1.7%15.7%10.4 $54.07 9/30/202211,560,000 shares $755.45 million +5.8%16.1%9.1 $65.35 9/15/202210,930,000 shares $819.86 million +0.5%15.3%7.5 $75.01 8/31/202210,880,000 shares $708.18 million +1.5%15.2%6 $65.09 8/15/202210,720,000 shares $859.10 million -2.3%15.0%5.7 $80.14 7/31/202210,970,000 shares $822.75 million -4.9%15.4%5.5 $75.00 7/15/202211,530,000 shares $961.49 million +1.9%16.2%5.8 $83.39 6/30/202211,320,000 shares $687.92 million +6.4%15.9%6.1 $60.77 6/15/202210,640,000 shares $666.70 million +4.0%15.0%6.3 $62.66 5/31/202210,230,000 shares $593.85 million -7.2%14.4%7.3 $58.05 5/15/202211,020,000 shares $575.57 million +8.7%15.5%7.7 $52.23 4/30/202210,140,000 shares $503.15 million -2.3%14.3%7.1 $49.62 4/15/202210,380,000 shares $645.53 million +3.3%14.7%6.8 $62.19 3/31/202210,050,000 shares $630.84 million +7.0%14.2%6.2 $62.77 3/15/20229,390,000 shares $563.78 million +2.5%13.3%5.6 $60.04 2/28/20229,160,000 shares $562.15 million +4.9%13.0%5.5 $61.37 2/15/20228,730,000 shares $532.27 million +6.5%12.4%5.2 $60.97 1/31/20228,200,000 shares $522.75 million -4.0%11.8%5 $63.75 1/15/20228,540,000 shares $578.76 million +6.1%N/A0 $67.77 12/31/20218,050,000 shares $610.03 million -1.2%11.6%4.9 $75.78 12/15/20218,150,000 shares $642.79 million +17.4%11.7%5.1 $78.87 11/30/20216,940,000 shares $554.51 million +18.6%10.0%4.8 $79.90 11/15/20215,850,000 shares $497.72 million +4.8%8.4%4.4 $85.08 10/29/20215,580,000 shares $509.62 million +15.8%8.0%4.4 $91.33 10/15/20214,820,000 shares $467.54 million +80.5%6.9%3.8 $97.00 9/30/20212,670,000 shares $298.85 million -15.8%3.8%2.4 $111.93 9/15/20213,170,000 shares $371.71 million +7.1%4.6%2.6 $117.26 8/31/20212,960,000 shares $369.85 million +0.7%4.4%2.4 $124.95 8/13/20212,940,000 shares $372.67 million +14.0%4.6%2.3 $126.76 7/30/20212,580,000 shares $312.23 million +11.2%4.1%1.9 $121.02 7/15/20212,320,000 shares $294.87 million -28.0%3.6%1.7 $127.10 6/30/20213,220,000 shares $521.29 million -4.2%5.0%2.2 $161.89 6/15/20213,360,000 shares $415.36 million +1.2%5.4%2.6 $123.62 5/28/20213,320,000 shares $392.36 million -14.2%5.3%2.4 $118.18 5/14/20213,870,000 shares $390.87 million +11.9%N/A2.2 $101.00 4/30/20213,460,000 shares $456.30 million -18.6%N/A1.8 $131.88 4/15/20214,250,000 shares $523.22 million -4.7%N/A2.1 $123.11 3/31/20214,460,000 shares $513.79 million +5.7%N/A2 $115.20 3/15/20214,220,000 shares $551.17 million +12.5%N/A1.7 $130.61 2/26/20213,750,000 shares $477.30 million +23.0%N/A1.5 $127.28 2/12/20213,050,000 shares $485.10 million +3.4%N/A1.4 $159.05 1/29/20212,950,000 shares $493.89 million -19.0%N/A1.5 $167.42 1/15/20213,640,000 shares $764.55 million -5.9%N/A2 $210.04 12/31/20203,870,000 shares $625.28 million +7.2%N/A2.3 $161.57 12/15/20203,610,000 shares $541.72 million -16.2%N/A2.7 $150.06 11/30/20204,310,000 shares $523.88 million -8.1%N/A4 $121.55 11/15/20204,690,000 shares $487.57 million -25.9%N/A5.2 $103.96 10/30/20206,330,000 shares $609.90 million +19.7%N/A6.5 $96.35 CRSP Short Interest - Frequently Asked Questions What is CRISPR Therapeutics' current short interest? Short interest is the volume of CRISPR Therapeutics shares that have been sold short but have not yet been closed out or covered. As of September 30th, investors have sold 21,350,000 shares of CRSP short. Learn More on CRISPR Therapeutics' current short interest. What is a good short interest ratio for CRISPR Therapeutics? The short interest ratio, also known as the "days to cover ratio", is calculated by dividing the number of shares of a stock sold short divided by its average trading volume. A short interest ratio ranging between 1 and 4 generally indicates strong positive sentiment about a stock and a lack of short sellers. A short interest ratio of 10 or greater indicates strong pessimism about a stock. CRSP shares currently have a short interest ratio of 7.0. Learn More on CRISPR Therapeutics's short interest ratio. Which institutional investors are shorting CRISPR Therapeutics? As of the most recent reporting period, the following institutional investors, funds, and major shareholders have reported short positions of CRISPR Therapeutics: Squarepoint Ops LLC, Nomura Holdings Inc., Group One Trading LLC, Bank of America Corp DE, Jane Street Group LLC, Caption Management LLC, Squarepoint Ops LLC, Walleye Capital LLC, Walleye Trading LLC, Capital Fund Management S.A., JPMorgan Chase & Co., and Bank of Montreal Can. These positions are disclosed in Form 13F filings with the Securities and Exchange Commission. Is CRISPR Therapeutics' short interest increasing or decreasing? CRISPR Therapeutics saw a drop in short interest during the month of September. As of September 30th, there was short interest totaling 21,350,000 shares, a drop of 10.3% from the previous total of 23,810,000 shares. Changes in short volume can be used to identify positive and negative investor sentiment. Investors that short sell a stock are betting that its price will decline in the future. An increase in short sale volume suggests bearish (negative) sentiment among investors. A decrease on short sale volume suggests bullish (positive) sentiment. How does CRISPR Therapeutics' short interest compare to its competitors? Here is how the short interest of companies compare to CRISPR Therapeutics: Allogene Therapeutics, Inc. (8.65%), Axsome Therapeutics, Inc. (6.77%), Beam Therapeutics Inc. (21.13%), KALA BIO, Inc. (26.25%), Moderna, Inc. (18.66%), Intellia Therapeutics, Inc. (27.70%), Twist Bioscience Corporation (21.50%), Vertex Pharmaceuticals Incorporated (1.39%), BioNTech SE Sponsored ADR (2.63%), Teva Pharmaceutical Industries Ltd. (4.35%), Which stocks are the most shorted right now? As of the most recent reporting period, the following stocks had the largest short interest positions: AppLovin Corporation ($15.71 billion), Robinhood Markets, Inc. ($7.56 billion), Reddit Inc. ($4.55 billion), Coinbase Global, Inc. ($4.53 billion), CoreWeave Inc. ($4.43 billion), Charter Communications, Inc. ($4.07 billion), Seagate Technology Holdings PLC ($3.94 billion), IonQ, Inc. ($3.78 billion), TC Energy Corporation ($3.13 billion), and Live Nation Entertainment, Inc. ($3.12 billion). View all of the most shorted stocks. What does it mean to sell short CRISPR Therapeutics stock? Short selling CRSP is an investing strategy that aims to generate trading profit from CRISPR Therapeutics as its price is falling. CRSP shares are trading up $0.69 today. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit. How does a short squeeze work against CRISPR Therapeutics? A short squeeze for CRISPR Therapeutics occurs when it has a large amount of short interest and its stock increases in price. This forces short sellers to cover their short interest positions by buying actual shares of CRSP, which in turn drives the price of the stock up even further. How often is CRISPR Therapeutics' short interest reported? Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including CRSP, twice per month. The most recent reporting period available is September, 30 2025. More Short Interest Resources from MarketBeat Related Companies Allogene Therapeutics Short Interest Axsome Therapeutics Short Interest Beam Therapeutics Short Interest KALA BIO Short Interest Moderna Short Interest Intellia Therapeutics Short Interest Twist Bioscience Short Interest Vertex Pharmaceuticals Short Interest BioNTech Short Interest Teva Pharmaceutical Industries Short Interest Short Interest Tools Stocks to Short Largest Short Interest Positions Short Interest Increases Short Interest Decreases Short Interest Reporting Dates This page (NASDAQ:CRSP) was last updated on 10/24/2025 by MarketBeat.com Staff From Our PartnersNEW LAW: Congress Approves Setup For Digital Dollar?Trump Ally Says Congress Approved the Setup for a Digital Dollar 2.0 But according to Rep. 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