NASDAQ:CUE Cue Biopharma (CUE) Stock Price, News & Analysis $37.05 -0.79 (-2.09%) Closing price 09/18/2026 04:00 PM EasternExtended Trading$37.02 -0.03 (-0.08%) As of 09/18/2026 07:37 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsInsider TradesNews and TrendsOptions ChainOwnershipSEC FilingsShort Interest About Cue Biopharma Stock (NASDAQ:CUE) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Cue Biopharma alerts:Sign Up Key Stats Today's Range$35.54▼$41.0050-Day Range$23.18▼$37.8452-Week Range$4.97▼$45.50Volume381,738 shsAverage Volume148,828 shsMarket Capitalization$268.98 millionP/E RatioN/ADividend YieldN/APrice Target$83.00Consensus RatingHold Company Overview Cue Biopharma, Inc. is a clinical-stage biotechnology company developing therapeutics that selectively activate and regulate antigen-specific T cells inside the body. Its approach is designed to direct the immune system toward cancer cells while potentially reducing the broad immune activation and toxicity associated with conventional immunotherapies. The company’s proprietary Immuno-STAT (Selective Targeting of Antigens for Remodeling of T cells) platform uses biologic molecules that combine peptide-major histocompatibility complex components with immune-modulating signals. Cue’s pipeline includes investigational treatments intended for oncology and immune-related diseases, including programs targeting tumor-associated antigens such as human papillomavirus 16 and Wilms tumor 1. Cue Biopharma is headquartered in Boston, Massachusetts, and focuses primarily on research, clinical development and strategic collaboration activities rather than commercialized products. Its lead programs have been evaluated in clinical studies for advanced cancers, including HPV16-positive malignancies and other solid tumors. The company is led by President and Chief Executive Officer Daniel R. Passeri.AI Generated. May Contain Errors. Read More Cue Biopharma Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks55th Percentile Overall ScoreCUE MarketRank™: Cue Biopharma scored higher than 55% of companies evaluated by MarketBeat, and ranked 406th out of 897 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion3.8 / 5Analyst RatingHold Consensus RatingCue Biopharma has received a consensus rating of Hold. The company's average rating score is 2.33, and is based on no strong buy ratings, 2 buy ratings, no hold ratings, and 1 sell rating.Upside PotentialCue Biopharma has a consensus price target of $83.00, representing about 124.0% upside from its current price of $37.05.Amount of Analyst CoverageCue Biopharma has only been the subject of 3 research reports in the past 90 days.Read more about Cue Biopharma's stock forecast and price target. Earnings and Valuation0.0 / 5Proj. Earnings GrowthN/A Price to Earnings Ratio vs. the MarketThe P/E ratio of Cue Biopharma is -1.37, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Cue Biopharma is -1.37, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioCue Biopharma has a P/B Ratio of 3.68. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.Read more about Cue Biopharma's valuation and earnings. Short Interest3.0 / 5Short Interest LevelHealthy Percentage of Shares Shorted5.13% of the float of Cue Biopharma has been sold short.Short Interest Ratio / Days to CoverCue Biopharma has a short interest ratio ("days to cover") of 1.76, which is generally considered an acceptable ratio of short interest to trading volume.Change versus previous monthShort interest in Cue Biopharma has recently decreased by 2.76%, indicating that investor sentiment is improving. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldCue Biopharma does not currently pay a dividend.Dividend GrowthCue Biopharma does not have a long track record of dividend growth. News and Social Media2.7 / 5News Sentiment0.33 News SentimentCue Biopharma has a news sentiment score of 0.33. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.56 average news sentiment score of Healthcare companies.News Coverage This WeekMarketBeat has tracked 9 news articles for Cue Biopharma this week, compared to 3 articles on an average week.MarketBeat Follows3 people have added Cue Biopharma to their MarketBeat watchlist in the last 30 days. This is an increase of 50% compared to the previous 30 days. Company Ownership1.7 / 5Insider TradingSelling Shares Insider Buying vs. Insider SellingIn the past three months, Cue Biopharma insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $2,041,555.00 in company stock.Percentage Held by Insiders14.56% of the stock of Cue Biopharma is held by insiders. A high percentage of insider ownership can be a sign of company health.Percentage Held by Institutions35.04% of the stock of Cue Biopharma is held by institutions.Read more about Cue Biopharma's insider trading history. Receive CUE Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Cue Biopharma and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. CUE Stock News HeadlinesCue Biopharma Reports Positive Phase 2 Topline Results for CUE-221 in Chronic Spontaneous Urticaria3 hours ago | quiverquant.comQCue Biopharma Announces Positive Topline Results from CUE-221 Phase 2 Study in Chronic Spontaneous Urticaria3 hours ago | globenewswire.comElon Musk’s Hushed FCC Filing. Sept 25th.Elon Musk quietly filed a document with the federal government tied to artificial intelligence, one of the largest markets in the world. James Altucher, who previously flagged Nvidia in 2008 and Bitcoin in 2013, says the filing could rival Tesla, SpaceX and xAI combined. Few investors know this filing exists, but that is expected to change quickly.September 20 at 1:00 AM | Paradigm Press (Ad)B. Riley Financial Begins Coverage on Cue Biopharma (NASDAQ:CUE)September 20 at 1:48 AM | americanbankingnews.comCue Biopharma is a new buy at B Riley on valuationSeptember 19 at 12:34 AM | msn.comB Riley Securities initiates coverage of Cue Biopharma with buySeptember 18 at 11:43 PM | msn.comCue Biopharma is a new Buy at B. Riley on valuationSeptember 18 at 1:42 PM | seekingalpha.comCue Biopharma consensus price target cut by 21.30% to $92.31September 15, 2026 | msn.comSee More Headlines CUE Stock Analysis - Frequently Asked Questions How have CUE shares performed this year? Cue Biopharma's stock was trading at $274.86 on January 1st, 2026. Since then, CUE stock has decreased by 86.5% and is now trading at $37.05. How were Cue Biopharma's earnings last quarter? Cue Biopharma, Inc. (NASDAQ:CUE) issued its quarterly earnings results on Friday, August, 14th. The company reported ($24.14) EPS for the quarter, missing analysts' consensus estimates of ($1.69) by $22.45. The business had revenue of $7.88 million for the quarter, compared to the consensus estimate of $3 million. Cue Biopharma had a negative net margin of 435.83% and a negative trailing twelve-month return on equity of 620.06%. When did Cue Biopharma's stock split? Cue Biopharma's stock reverse split before market open on Thursday, April 23rd 2026.The 1-30 reverse split was announced on Wednesday, April 22nd 2026. The number of shares owned by shareholders was adjusted after the closing bell on Wednesday, April 22nd 2026. An investor that had 100 shares of stock prior to the reverse split would have 3 shares after the split. When did Cue Biopharma IPO? Cue Biopharma (CUE) raised $62 million in an IPO on Tuesday, January 2nd 2018. The company issued 8,820,710 shares at a price of $6.00-$8.00 per share. Who are Cue Biopharma's major shareholders? Top institutional shareholders of Cue Biopharma include BlackRock Inc. (1.38%), ADAR1 Capital Management LLC (1.31%), Citadel Advisors LLC (0.35%) and Texas Capital Bank Wealth Management Services Inc (0.54%). Insiders that own company stock include Shao-Lee Lin, Sumita Ray, Michael Vincent Meluzio and Daniel R Passeri. View institutional ownership trends. How do I buy shares of Cue Biopharma? Shares of CUE stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Cue Biopharma own? Based on aggregate information from My MarketBeat watchlists, some other companies that Cue Biopharma investors own include NVIDIA (NVDA), Tesla (TSLA), Advanced Micro Devices (AMD), Meta Platforms (META), JPMorgan Chase & Co. (JPM), Netflix (NFLX) and Company Calendar Last Earnings8/14/2026Today9/20/2026Next Earnings (Estimated)11/12/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Green Zone (4m+) 1-Year History Sep 25 Dec 25 Mar 26 Jun 26 Sep 26 CUE's financial health is in the Green zone, according to TradeSmith. CUE has been in this zone for over 4 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorHealthcare Industry Biotechnology Sub-IndustryBiotechnology Current SymbolNASDAQ:CUE CIK1645460 Webwww.cuebiopharma.com Phone(617) 949-2680FaxN/AEmployees29Year Founded2015Price Target and Rating Average Price Target for Cue Biopharma$83.00 High Price Target$83.00 Low Price Target$83.00 Potential Upside/Downside+124.0%Consensus RatingHold Rating Score (0-4)2.33 Research Coverage3 Analysts Profitability EPS (Trailing Twelve Months)($27.02) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$26.60 million Net Margins-435.83% Pretax Margin-434.50% Return on Equity-620.06% Return on Assets-291.15% Debt Debt-to-Equity RatioN/A Current Ratio1.25 Quick Ratio1.25 Sales & Book Value Annual Sales$27.47 million Price / Sales9.79 Cash FlowN/A Price / Cash FlowN/A Book Value$10.08 per share Price / Book3.68Miscellaneous Outstanding Shares7,260,000Free Float6,206,000Market Cap$268.98 million OptionableOptionable Beta2.45 Social Links The 10 Best High-Yield Dividend Stocks for 2026Discover the 10 Best High-Yield Dividend Stocks for 2026 and secure reliable income in uncertain markets. Download the report now to identify top dividend payers and avoid common yield traps.Get This Free Report This page (NASDAQ:CUE) was last updated on 9/20/2026 by MarketBeat.com Staff. From Our Partners$40,000,000,000,000The national debt just hit 40 trillion dollars, and the U.S. now spends more on interest payments than on its ...American Alternative | SponsoredBank of America: 'Digital Dollar Inevitable'Bank of America just revealed your expiration date. 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