Hepion Pharmaceuticals (HEPA) Stock Price, News & Analysis

Company Overview

Hepion Pharmaceuticals, Inc. is a clinical‐stage biopharmaceutical company focused on developing novel therapies for chronic liver diseases. The company harnesses epigenetic and autophagy‐modulating approaches to address high unmet medical needs in conditions such as nonalcoholic steatohepatitis (NASH), fibrosis and hepatocellular carcinoma. Hepion’s research platform is designed to identify and advance small molecules that can halt or reverse liver damage by targeting key pathways involved in inflammation, cellular stress and tissue remodeling.

The company’s lead therapeutic candidate, CRV431, is a cyclophilin inhibitor being evaluated in Phase 2 clinical trials for the treatment of NASH with bridging fibrosis. CRV431 has demonstrated the potential to reduce inflammation, fibrosis and lipid accumulation in preclinical models. In addition to CRV431, Hepion’s pipeline includes early‐stage compounds aimed at inhibiting VPS34, an enzyme involved in autophagy, which may offer complementary mechanisms to improve liver function and slow disease progression. Hepion collaborates with academic institutions and contract research organizations to advance its programs from preclinical development into human studies.

Hepion Pharmaceuticals is headquartered in the United States and conducts multi‐center trials across North America and Europe. The company is led by a management team with extensive experience in pharmaceutical development, regulatory strategy and commercialization. Hepion seeks to leverage its scientific expertise and strategic partnerships to deliver safe and effective therapies for patients suffering from chronic liver disorders.

Key Stats

• Today's Range: $0.05 to $0.06
• 50-Day Range: $0.04 to $0.07
• 52-Week Range: $0.03 to $0.10
• Volume: 20,128 shs
• Average Volume: 17,495 shs
• Market Capitalization: $607.20 thousand
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: N/A
• Consensus Rating: N/A

HEPA Stock Analysis - Frequently Asked Questions

How have HEPA shares performed this year?

Hepion Pharmaceuticals' stock was trading at $0.06 at the beginning of the year. Since then, HEPA stock has decreased by 11.5% and is now trading at $0.0531.

How were Hepion Pharmaceuticals' earnings last quarter?

Hepion Pharmaceuticals, Inc. (NASDAQ:HEPA) issued its quarterly earnings results on Sunday, November, 15th. The company reported ($690.00) earnings per share (EPS) for the quarter, missing analysts' consensus estimates of ($510.00) by $180.00.

When did Hepion Pharmaceuticals' stock split?

Hepion Pharmaceuticals's stock reverse split on the morning of Tuesday, March 18th 2025.The 1-50 reverse split was announced on Friday, March 14th 2025. The number of shares owned by shareholders was adjusted after the market closes on Monday, March 17th 2025. An investor that had 100 shares of stock prior to the reverse split would have 2 shares after the split.

How do I buy shares of Hepion Pharmaceuticals?

Shares of HEPA stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of Hepion Pharmaceuticals own?

Based on aggregate information from My MarketBeat watchlists, some other companies that Hepion Pharmaceuticals investors own include VBI Vaccines (VBIV), Sorrento Therapeutics (SRNE), FuelCell Energy (FCEL), NVIDIA (NVDA), Tonix Pharmaceuticals (TNXP), Advanced Micro Devices (AMD) and Meta Platforms (META).

Company Calendar

• Last Earnings: 11/15/2020
• Today: 5/06/2026
• Next Earnings (Estimated): 5/12/2026
• Fiscal Year End: 12/31/2026

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Medical
• Industry: Pharmaceutical preparations
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NASDAQ:HEPA
• CIK: 1583771
• Web: www.hepionpharma.com
• Phone: (732) 902-4000
• Fax: 732-902-4100
• Employees: 20
• Year Founded: 2013

Profitability

• EPS (Trailing Twelve Months): ($72.15)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: -$48.93 million
• Net Margins: N/A
• Pretax Margin: N/A
• Return on Equity: -812.56%
• Return on Assets: -207.31%

Debt

• Debt-to-Equity Ratio: N/A
• Current Ratio: 1.30
• Quick Ratio: 1.30

Sales & Book Value

• Annual Sales: N/A
• Price / Sales: N/A
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: $1.29 per share
• Price / Book: 0.04

Miscellaneous

• Outstanding Shares: 11,435,000
• Free Float: 6,631,000
• Market Cap: $607.20 thousand
• Optionable: No Data
• Beta: 1.52