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NASDAQ:HOWL

Werewolf Therapeutics (HOWL) Stock Price, News & Analysis

Werewolf Therapeutics logo
$0.41 +0.00 (+0.68%)
As of 12:41 PM Eastern
This is a fair market value price provided by Massive. Learn more.

About Werewolf Therapeutics Stock (NASDAQ:HOWL)

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Key Stats

Today's Range
$0.40
$0.42
50-Day Range
$0.31
$0.50
52-Week Range
$0.27
$2.38
Volume
62,496 shs
Average Volume
551,160 shs
Market Capitalization
$20.02 million
P/E Ratio
N/A
Dividend Yield
N/A
Price Target
$3.75
Consensus Rating
Hold

Company Overview

Werewolf Therapeutics, Inc. (NASDAQ: HOWL) is a clinical-stage biotechnology company focused on the development of next-generation immunotherapies for the treatment of solid tumors. The company’s proprietary Conditional Activation Platform is designed to keep therapeutic molecules inert in healthy tissues and selectively activate them within the tumor microenvironment, aiming to enhance anti-tumor efficacy while minimizing systemic toxicity.

Leveraging this platform, Werewolf Therapeutics is advancing multiple programs that include conditionally activated cytokine candidates and bi-specific antibody constructs. These investigational agents are engineered to engage key immune pathways—such as T-cell activation and pro-inflammatory cytokine signaling—only when proteolytically processed by enzymes present in the tumor milieu. This approach is intended to drive a potent, localized immune response against cancer cells while reducing the risk of adverse events associated with systemic cytokine exposure.

The company’s pipeline spans both preclinical and early clinical stages, with lead programs targeting interleukin and tumor-necrosis factor family members. In addition to internal research efforts, Werewolf Therapeutics collaborates with academic institutions and industry partners to explore combination regimens that may further enhance the anti-tumor activity of its conditional agents.

Founded in 2019 and headquartered in Cambridge, Massachusetts, Werewolf Therapeutics is led by a management team with extensive experience in immuno-oncology drug discovery and clinical development. The company is focused on advancing its pipeline through regulatory milestones and clinical proof-of-concept studies in the United States.

AI Generated. May Contain Errors.

Werewolf Therapeutics Stock Analysis - MarketRank™

See Top-Rated MarketRank™ Stocks
52nd Percentile Overall Score

HOWL MarketRank™: 

Werewolf Therapeutics scored higher than 52% of companies evaluated by MarketBeat, and ranked 292nd out of 909 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

  • Consensus Rating

    Werewolf Therapeutics has received a consensus rating of Hold. The company's average rating score is 2.14, and is based on no strong buy ratings, 2 buy ratings, 4 hold ratings, and 1 sell rating.

  • Upside Potential

    Werewolf Therapeutics has a consensus price target of $3.75, representing about 810.2% upside from its current price of $0.41.

  • Amount of Analyst Coverage

    Werewolf Therapeutics has only been the subject of 1 research reports in the past 90 days.

  • Read more about Werewolf Therapeutics' stock forecast and price target.
  • Earnings Growth

    Earnings for Werewolf Therapeutics are expected to grow in the coming year, from ($1.08) to ($0.99) per share.

  • Price to Earnings Ratio vs. the Market

    The P/E ratio of Werewolf Therapeutics is -0.54, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

  • Price to Earnings Ratio vs. Sector

    The P/E ratio of Werewolf Therapeutics is -0.54, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

  • Price to Book Value per Share Ratio

    Werewolf Therapeutics has a P/B Ratio of 0.81. P/B Ratios below 1 indicate that a company could be undervalued with respect to its assets and liabilities.

  • Read more about Werewolf Therapeutics' valuation and earnings.
  • Percentage of Shares Shorted

    2.96% of the float of Werewolf Therapeutics has been sold short.
  • Short Interest Ratio / Days to Cover

    Werewolf Therapeutics has a short interest ratio ("days to cover") of 1.3, which is generally considered an acceptable ratio of short interest to trading volume.
  • Change versus previous month

    Short interest in Werewolf Therapeutics has recently increased by 17.67%, indicating that investor sentiment is decreasing significantly.
  • Dividend Yield

    Werewolf Therapeutics does not currently pay a dividend.

  • Dividend Growth

    Werewolf Therapeutics does not have a long track record of dividend growth.

  • News Coverage This Week

    MarketBeat has tracked 1 news article for Werewolf Therapeutics this week, compared to 5 articles on an average week.
  • Search Interest

    Only 1 people have searched for HOWL on MarketBeat in the last 30 days. This is a decrease of -75% compared to the previous 30 days.
  • MarketBeat Follows

    3 people have added Werewolf Therapeutics to their MarketBeat watchlist in the last 30 days.
  • Insider Buying vs. Insider Selling

    In the past three months, Werewolf Therapeutics insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $971,147.00 in company stock.

  • Percentage Held by Insiders

    23.60% of the stock of Werewolf Therapeutics is held by insiders. A high percentage of insider ownership can be a sign of company health.

  • Percentage Held by Institutions

    64.84% of the stock of Werewolf Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.

  • Read more about Werewolf Therapeutics' insider trading history.
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HOWL Stock News Headlines

Trump Takes Emergency Action - Plus Elon Musk's New Venture
Elon Musk has quietly launched a new venture - one that has nothing to do with rockets, EVs, or Neuralink. Trump has issued emergency support to accelerate the rollout, and it's already live in multiple states. The Financial Times reports Sam Altman is personally calling people to build this for OpenAI. A few little-known companies control the entire supply chain - meaning anyone who wants access must go through them. Their stocks are available to buy right now.tc pixel
See More Headlines

HOWL Stock Analysis - Frequently Asked Questions

Werewolf Therapeutics' stock was trading at $0.6335 at the beginning of 2026. Since then, HOWL stock has decreased by 35.0% and is now trading at $0.4120.

Werewolf Therapeutics, Inc. (NASDAQ:HOWL) released its earnings results on Friday, July, 31st. The company reported $0.08 earnings per share for the quarter, beating the consensus estimate of ($0.28) by $0.36. The business earned $21 million during the quarter, compared to analyst estimates of $21 million.

Werewolf Therapeutics (HOWL) raised $120 million in an IPO on Wednesday, April 28th 2021. The company issued 7,500,000 shares at $15.00-$17.00 per share. Jefferies, SVB Leerink and Evercore ISI acted as the underwriters for the IPO and H.C. Wainwright & Co. was co-manager.

Top institutional investors of Werewolf Therapeutics include Bank of America Corp DE (0.64%) and BlackRock Inc. (0.21%). Insiders that own company stock include Bioventures 2014 LP Mpm, Ra Capital Management, LP and Luke Evnin.
View institutional ownership trends
.

Shares of HOWL stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

Based on aggregate information from My MarketBeat watchlists, some other companies that Werewolf Therapeutics investors own include NVIDIA (NVDA), Broadcom (AVGO), Meta Platforms (META), Arista Networks (ANET), Adobe (ADBE), e.l.f. Beauty (ELF) and Jabil (JBL).

Company Calendar

Last Earnings
7/31/2026
Today
8/19/2026
Next Earnings (Estimated)
11/03/2026
Fiscal Year End
12/31/2026

Industry, Sector and Symbol

Stock Exchange
NASDAQ
Industry
Biotechnology
Sub-Industry
Biotechnology
Current Symbol
NASDAQ:HOWL
CIK
1785530
Fax
N/A
Employees
40
Year Founded
2017

Price Target and Rating

High Price Target
$7.00
Low Price Target
$1.00
Potential Upside/Downside
+810.2%
Consensus Rating
Hold
Rating Score (0-4)
2.14
Research Coverage
7 Analysts

Profitability

EPS (Trailing Twelve Months)
($0.76)
Trailing P/E Ratio
N/A
Forward P/E Ratio
N/A
P/E Growth
N/A
Net Income
-$60.82 million
Net Margins
N/A
Pretax Margin
-164.82%
Return on Equity
-166.99%
Return on Assets
-59.88%

Debt

Debt-to-Equity Ratio
N/A
Current Ratio
2.91
Quick Ratio
2.91

Sales & Book Value

Annual Sales
$1.88 million
Price / Sales
10.65
Cash Flow
N/A
Price / Cash Flow
N/A
Book Value
$0.51 per share
Price / Book
0.81

Miscellaneous

Outstanding Shares
48,600,000
Free Float
37,130,000
Market Cap
$20.02 million
Optionable
Optionable
Beta
0.29

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This page (NASDAQ:HOWL) was last updated on 8/19/2026 by MarketBeat.com Staff.
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