Heron Therapeutics (HRTX) Short Interest Ratio & Short Volume $1.35 +0.03 (+2.27%) Closing price 10/15/2025 04:00 PM EasternExtended Trading$1.35 0.00 (0.00%) As of 10/15/2025 07:16 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Short Interest Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock Heron Therapeutics Short Interest DataHeron Therapeutics (HRTX) has a short interest of 32.96 million shares. This marks a 1.76% increase in short interest from the previous month. The short interest ratio (days to cover) is 19.3, indicating that it would take 19.3 days of the average trading volume of 1.65 million shares to cover all short positions.Current Short Interest32,960,000 sharesPrevious Short Interest32,390,000 sharesChange Vs. Previous Month+1.76%Dollar Volume Sold Short$40.87 millionShort Interest Ratio19.3 Days to CoverLast Record DateSeptember 15, 2025Outstanding Shares183,320,000 sharesPercentage of Shares Shorted17.98%Today's Trading Volume1,017,768 sharesAverage Trading Volume1,651,597 sharesToday's Volume Vs. Average62% Short Selling Heron Therapeutics? Sign up to receive the latest short interest report for Heron Therapeutics and its competitors with MarketBeat's FREE newsletter. 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Skip Charts & View Short Interest HistoryShort Interest ChartDays to Cover ChartShort Percent of Float ChartHRTX Short Interest Over TimeHRTX Days to Cover Over TimeHRTX Percentage of Float Shorted Over Time Heron Therapeutics Short Interest History Export to ExcelReport DateTotal Shares Sold ShortDollar Volume Sold ShortChange from Previous ReportPercentage of Float ShortedDays to CoverPrice on Report Date 9/15/202532,960,000 shares $40.87 million +1.8%N/A19.3 $1.24 8/31/202532,390,000 shares $43.73 million -2.5%22.4%19.5 $1.35 8/15/202533,230,000 shares $44.20 million -5.8%N/A20.3 $1.33 7/31/202535,260,000 shares $61.00 million -0.2%24.4%22.7 $1.73 7/15/202535,320,000 shares $72.05 million -4.3%N/A23.1 $2.04 6/30/202536,920,000 shares $76.42 million +7.9%25.7%23.4 $2.07 6/15/202534,210,000 shares $66.03 million +0.7%23.8%23.4 $1.93 5/31/202533,960,000 shares $64.18 million -1.3%23.7%22.3 $1.89 5/15/202534,410,000 shares $64.35 million +3.3%24.0%17.6 $1.87 4/30/202533,300,000 shares $80.59 million +1.0%N/A17.9 $2.42 Get the Latest News and Ratings for HRTX and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Heron Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 4/15/202532,960,000 shares $63.28 million +1.4%23.0%19.9 $1.92 3/31/202532,520,000 shares $71.54 million +1.4%22.7%18.8 $2.20 3/15/202532,070,000 shares $74.40 million +2.4%22.4%17.5 $2.32 2/28/202531,330,000 shares $77.39 million +1.8%21.9%10.2 $2.47 2/15/202530,770,000 shares $54.77 million -0.2%21.5%10.7 $1.78 1/31/202530,840,000 shares $52.43 million -0.7%N/A10 $1.70 1/15/202531,060,000 shares $47.21 million +1.1%N/A10 $1.52 12/31/202430,710,000 shares $46.99 million +2.4%N/A9.9 $1.53 12/15/202429,980,000 shares $47.97 million +8.9%N/A9.6 $1.60 11/30/202427,540,000 shares $32.77 million -1.3%N/A8.8 $1.19 11/15/202427,910,000 shares $33.21 million -3.1%N/A15.3 $1.19 10/31/202428,810,000 shares $50.13 million -6.0%N/A15.7 $1.74 10/15/202430,640,000 shares $55.15 million -3.3%N/A14.9 $1.80 9/30/202431,700,000 shares $63.08 million -10.6%N/A14.4 $1.99 9/15/202435,440,000 shares $66.27 million -1.3%N/A14.9 $1.87 8/31/202435,920,000 shares $69.33 million -0.1%N/A15.5 $1.93 8/15/202435,960,000 shares $70.12 million +0.9%N/A14.9 $1.95 7/31/202435,630,000 shares $105.82 million -0.1%N/A14.9 $2.97 7/15/202435,660,000 shares $118.03 million +8.7%N/A14.7 $3.31 6/30/202432,820,000 shares $114.87 million +7.7%N/A14 $3.50 6/15/202430,470,000 shares $109.69 million +1.4%N/A14.5 $3.60 5/31/202430,040,000 shares $111.15 million -0.8%N/A12.3 $3.70 5/15/202430,270,000 shares $90.81 million +10.9%N/A12.6 $3.00 4/30/202427,290,000 shares $63.31 million +7.3%N/A11.6 $2.32 4/15/202425,430,000 shares $75.02 million -0.5%N/A9.8 $2.95 3/31/202425,550,000 shares $70.77 million +0.5%N/A8.8 $2.77 3/15/202425,430,000 shares $77.82 million +3.7%N/A8.4 $3.06 2/29/202424,530,000 shares $65.25 million -0.4%N/A8.8 $2.66 2/15/202424,620,000 shares $70.91 million +1.2%N/A8.4 $2.88 1/31/202424,330,000 shares $58.64 million +13.1%N/A6.6 $2.41 1/15/202421,520,000 shares $46.27 million +6.5%N/A6.5 $2.15 12/31/202320,210,000 shares $34.36 million -3.8%N/A6 $1.70 12/15/202321,000,000 shares $38.01 million -2.7%N/A6.8 $1.81 11/30/202321,580,000 shares $26.54 million +22.7%N/A7.4 $1.23 11/15/202317,590,000 shares $15.13 million -4.5%N/A6.4 $0.86 10/31/202318,410,000 shares $11.73 million -4.9%N/A9.1 $0.64 10/15/202319,360,000 shares $13.99 million -26.5%N/A8.9 $0.72 9/30/202326,330,000 shares $27.12 million +2.3%N/A12.8 $1.03 9/15/202325,750,000 shares $31.16 million +1.7%N/A13.4 $1.21 8/31/202325,320,000 shares $41.52 million -8.8%N/A12.7 $1.64 8/15/202327,760,000 shares $46.50 million +14.2%N/A13.2 $1.68 7/31/202324,310,000 shares $40.35 million +9.4%N/A10.4 $1.66 7/15/202322,220,000 shares $28.22 million -1.0%N/A10.1 $1.27 6/30/202322,440,000 shares $26.03 million -2.0%N/A9.7 $1.16 6/15/202322,890,000 shares $29.99 million -2.1%N/A8.9 $1.31 5/31/202323,380,000 shares $26.65 million +8.0%N/A9 $1.14 5/15/202321,650,000 shares $28.79 million -2.9%N/A8.8 $1.33 4/30/202322,300,000 shares $53.30 million -3.8%N/A10.8 $2.39 4/15/202323,190,000 shares $63.31 million +0.2%N/A10.8 $2.73 3/31/202323,150,000 shares $34.96 million +1.5%N/A10.9 $1.51 3/15/202322,800,000 shares $53.81 million -2.0%N/A12.7 $2.36 2/28/202323,270,000 shares $55.15 million -11.0%N/A10.2 $2.37 2/15/202326,140,000 shares $68.75 million -2.4%N/A11.2 $2.63 1/31/202326,790,000 shares $72.60 million -1.0%N/A10.5 $2.71 1/15/202327,070,000 shares $85.81 million +8.2%N/A10.7 $3.17 12/30/202225,030,000 shares $62.58 million -13.2%N/A9.7 $2.50 12/15/202228,840,000 shares $73.25 million +2.2%N/A10.8 $2.54 11/30/202228,220,000 shares $76.48 million -0.6%N/A10 $2.71 11/15/202228,400,000 shares $90.88 million -1.3%N/A10.1 $3.20 10/31/202228,770,000 shares $110.76 million -1.4%N/A9.3 $3.85 10/15/202229,180,000 shares $107.09 million -12.7%N/A9 $3.67 9/30/202233,420,000 shares $141.03 million +2.1%N/A10.1 $4.22 9/15/202232,720,000 shares $159.35 million +0.2%N/A9.7 $4.87 8/31/202232,650,000 shares $133.54 million -4.0%N/A10.8 $4.09 8/15/202234,000,000 shares $182.58 million -15.9%N/A11.2 $5.37 7/31/202240,430,000 shares $112.40 million +0.6%N/A14.3 $2.78 7/15/202240,180,000 shares $118.13 million +10.3%N/A14.9 $2.94 6/30/202236,440,000 shares $101.67 million -6.5%47.0%13.8 $2.79 6/15/202238,980,000 shares $99.40 million +5.5%50.3%15.5 $2.55 5/31/202236,960,000 shares $121.97 million -0.1%N/A14.6 $3.30 5/15/202236,980,000 shares $132.76 million -0.1%N/A14.4 $3.59 4/30/202237,010,000 shares $167.29 million -0.5%N/A15.7 $4.52 4/15/202237,200,000 shares $218.36 million -5.3%N/A16.2 $5.87 3/31/202239,280,000 shares $224.68 million +16.0%N/A17.1 $5.72 3/15/202233,850,000 shares $163.83 million -2.6%N/A15 $4.84 2/28/202234,750,000 shares $246.73 million -1.4%N/A15.2 $7.10 2/15/202235,240,000 shares $311.52 million +1.7%N/A16.9 $8.84 1/31/202234,640,000 shares $301.71 million -6.3%N/A16.5 $8.71 1/15/202236,960,000 shares $321.55 million +0.9%N/A0 $8.70 12/31/202136,650,000 shares $334.61 million +7.9%N/A18.9 $9.13 12/15/202133,970,000 shares $306.41 million +8.1%N/A17.6 $9.02 11/30/202131,430,000 shares $297.01 million +2.1%N/A18.8 $9.45 11/15/202130,790,000 shares $336.53 million +3.6%N/A21.4 $10.93 10/29/202129,730,000 shares $327.33 million +5.2%N/A21.4 $11.01 10/15/202128,270,000 shares $299.38 million +5.1%N/A21.4 $10.59 9/30/202126,900,000 shares $287.56 million +2.0%N/A20.2 $10.69 9/15/202126,370,000 shares $307.47 million -3.1%N/A21.3 $11.66 8/31/202127,220,000 shares $317.66 million +5.9%N/A21.3 $11.67 8/13/202125,710,000 shares $284.10 million +0.1%N/A17.3 $11.05 7/30/202125,690,000 shares $317.53 million +5.9%N/A14 $12.36 7/15/202124,250,000 shares $317.43 million +2.2%N/A13.9 $13.09 6/30/202123,720,000 shares $368.13 million -1.4%N/A13.8 $15.52 6/15/202124,050,000 shares $372.05 million +1.6%N/A14.5 $15.47 5/28/202123,680,000 shares $314.23 million +11.8%N/A14.5 $13.27 5/14/202121,180,000 shares $329.03 million +0.8%N/A14.3 $15.54 4/30/202121,010,000 shares $370.20 million -1.9%N/A20.4 $17.62 4/15/202121,410,000 shares $369.75 million +1.5%N/A21.2 $17.27 3/31/202121,100,000 shares $322.83 million +2.7%N/A20.9 $15.30 3/15/202120,550,000 shares $348.12 million +2.0%N/A19 $16.94 2/26/202120,150,000 shares $363.71 million +2.2%N/A19.4 $18.05 2/12/202119,710,000 shares $364.83 million +3.0%N/A19.1 $18.51 1/29/202119,140,000 shares $351.41 million +7.8%N/A17.9 $18.36 1/15/202117,760,000 shares $325.72 million +1.3%N/A17.2 $18.34 12/31/202017,530,000 shares $372.86 million -0.4%N/A18.8 $21.27 12/15/202017,600,000 shares $316.10 million -5.2%N/A19.8 $17.96 11/30/202018,560,000 shares $333.89 million +2.5%N/A23 $17.99 11/15/202018,100,000 shares $328.15 million +3.6%N/A23.2 $18.13 10/30/202017,480,000 shares $280.38 million +0.5%N/A24.2 $16.04 HRTX Short Interest - Frequently Asked Questions What is Heron Therapeutics' current short interest? Short interest is the volume of Heron Therapeutics shares that have been sold short but have not yet been closed out or covered. As of September 15th, investors have sold 32,960,000 shares of HRTX short. Learn More on Heron Therapeutics' current short interest. What is a good short interest ratio for Heron Therapeutics? The short interest ratio, also known as the "days to cover ratio", is calculated by dividing the number of shares of a stock sold short divided by its average trading volume. A short interest ratio ranging between 1 and 4 generally indicates strong positive sentiment about a stock and a lack of short sellers. A short interest ratio of 10 or greater indicates strong pessimism about a stock. HRTX shares currently have a short interest ratio of 19.0. Learn More on Heron Therapeutics's short interest ratio. Which institutional investors are shorting Heron Therapeutics? As of the most recent reporting period, the following institutional investors, funds, and major shareholders have reported short positions of Heron Therapeutics: Group One Trading LLC, and Simplex Trading LLC. These positions are disclosed in Form 13F filings with the Securities and Exchange Commission. Is Heron Therapeutics' short interest increasing or decreasing? Heron Therapeutics saw a increase in short interest during the month of September. As of September 15th, there was short interest totaling 32,960,000 shares, an increase of 1.8% from the previous total of 32,390,000 shares. Changes in short volume can be used to identify positive and negative investor sentiment. Investors that short sell a stock are betting that its price will decline in the future. An increase in short sale volume suggests bearish (negative) sentiment among investors. A decrease on short sale volume suggests bullish (positive) sentiment. How does Heron Therapeutics' short interest compare to its competitors? Here is how the short interest of companies in the industry of "pharmaceutical products" compare to Heron Therapeutics: Precigen, Inc. (23.95%), Xencor, Inc. (13.45%), Oculis Holding AG (0.03%), Oruka Therapeutics, Inc. (10.00%), BGM Group Ltd. (0.20%), Mind Medicine (MindMed) Inc. (14.74%), Valneva SE Sponsored ADR (0.02%), ProKidney Corp. (10.19%), AnaptysBio, Inc. (36.77%), Kura Oncology, Inc. (12.50%), Which stocks are the most shorted right now? As of the most recent reporting period, the following stocks had the largest short interest positions: AppLovin Corporation ($8.81 billion), Canadian Natural Resources Limited ($5.82 billion), Reddit Inc. ($5.19 billion), Coinbase Global, Inc. ($4.52 billion), Robinhood Markets, Inc. ($4.30 billion), Charter Communications, Inc. ($3.75 billion), CoreWeave Inc. ($3.66 billion), Seagate Technology Holdings PLC ($3.57 billion), Live Nation Entertainment, Inc. ($3.33 billion), and Rocket Lab Corporation ($3.26 billion). View all of the most shorted stocks. What does it mean to sell short Heron Therapeutics stock? Short selling HRTX is an investing strategy that aims to generate trading profit from Heron Therapeutics as its price is falling. HRTX shares are trading up $0.03 today. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit. How does a short squeeze work against Heron Therapeutics? A short squeeze for Heron Therapeutics occurs when it has a large amount of short interest and its stock increases in price. This forces short sellers to cover their short interest positions by buying actual shares of HRTX, which in turn drives the price of the stock up even further. How often is Heron Therapeutics' short interest reported? Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including HRTX, twice per month. The most recent reporting period available is September, 15 2025. More Short Interest Resources from MarketBeat Related Companies Precigen Short Squeeze Xencor Short Squeeze Oculis Short Squeeze Oruka Therapeutics Short Squeeze BGM Group Short Squeeze Mind Medicine (MindMed) Short Squeeze Valneva Short Squeeze ProKidney Short Squeeze AnaptysBio Short Squeeze Kura Oncology Short Squeeze Short Interest Tools Stocks to Short Largest Short Interest Positions Short Interest Increases Short Interest Decreases Short Interest Reporting Dates This page (NASDAQ:HRTX) was last updated on 10/16/2025 by MarketBeat.com Staff From Our PartnersURGENT: The Market's 3 Red Flags Are FlashingHere’s the uncomfortable truth: The smartest investors in the world are already preparing for a crash befor...StockEarnings | SponsoredGenerate up to $5,000/month with 10X less money?The secret to retiring without a million-dollar nest egg. 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