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Ionis Pharmaceuticals (IONS) Institutional Ownership

Ionis Pharmaceuticals logo
$70.27 +0.31 (+0.44%)
Closing price 10/9/2025 04:00 PM Eastern
Extended Trading
$71.74 +1.47 (+2.08%)
As of 04:49 AM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.
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Institutional Ownership Changes (13F Filings) for Ionis Pharmaceuticals (NASDAQ:IONS)

Current
Institutional Ownership
Percentage
93.86%
Number of
Institutional Buyers
(last 12 months)
190
Total
Institutional Inflows
(last 12 months)
$881.40M
Number of
Institutional Sellers
(last 12 months)
122
Total
Institutional Outflows
(last 12 months)
$2.43B
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IONS Institutional Buying and Selling by Quarter

Ionis Pharmaceuticals Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
10/9/2025Mitchell & Pahl Private Wealth LLC3,572$234K0.1%N/A0.002%
10/7/2025 Assenagon Asset Management S.A.312,297$20.43M0.0%+1,669.0%0.196%
10/7/2025 Sicart Associates LLC164,318$10.75M2.9%-11.3%0.103%
10/2/2025 GAMMA Investing LLC1,341$88K0.0%+44.2%0.001%
9/26/2025Corient Private Wealth LLC237,840$9.40M0.0%+0.3%0.149%
9/4/2025Osaic Holdings Inc.5,296$209K0.0%+123.2%0.003%
8/27/2025Orion Porfolio Solutions LLC5,600$221K0.0%N/A0.004%
8/27/2025Squarepoint Ops LLC134,395$5.31M0.0%-56.0%0.084%
8/19/2025Marex Group plc83,361$3.29M0.0%N/A0.052%
8/18/2025Hudson Bay Capital Management LP750,000$29.63M0.1%-28.6%0.471%
8/16/2025Nikko Asset Management Americas Inc.139,739$5.52M0.1%-1.9%0.088%
8/15/2025CANADA LIFE ASSURANCE Co46,501$1.84M0.0%+6.0%0.029%
8/15/2025Tower Research Capital LLC TRC 1,581$62K0.0%-84.0%0.001%
8/15/2025Exome Asset Management LLC121,116$4.79M2.5%-10.7%0.076%
8/15/2025Corient Private Wealth LLC237,931$9.40M0.0%+0.3%0.149%
8/15/2025E Fund Management Co. Ltd.16,160$638K0.0%-1.9%0.010%
8/15/2025Vestal Point Capital LP500,000$19.76M1.0%N/A0.314%
8/15/2025Vident Advisory LLC12,000$474K0.0%N/A0.008%
8/15/2025Teza Capital Management LLC6,604$261K0.2%-35.5%0.004%
8/15/2025Rafferty Asset Management LLC144,770$5.72M0.0%-17.9%0.091%
8/15/2025Oxford Asset Management LLP22,405$885K0.3%N/A0.014%
8/15/2025Orion Investment Co217,370$8.59M3.1%+1.0%0.136%
8/15/2025Orion Porfolio Solutions LLC5,600$221K0.0%N/A0.004%
8/15/2025Hudson Bay Capital Management LP750,000$29.63M0.1%-28.6%0.471%
8/15/2025Engineers Gate Manager LP33,118$1.31M0.0%N/A0.021%
8/15/2025Brevan Howard Capital Management LP32,732$1.29M0.0%+42.5%0.021%
8/15/2025Adage Capital Partners GP L.L.C.3,800,000$150.14M0.3%+253.3%2.384%
8/14/2025PDT Partners LLC54,365$2.15M0.1%-43.4%0.034%
8/14/2025Paloma Partners Management Co12,557$496K0.1%N/A0.008%
8/14/2025California State Teachers Retirement System145,104$5.73M0.0%+9.7%0.091%
8/14/2025Worldquant Millennium Advisors LLC74,438$2.94M0.0%N/A0.047%
8/14/2025Bayesian Capital Management LP16,600$656K0.1%+95.3%0.010%
8/14/2025Quantinno Capital Management LP17,542$693K0.0%+106.0%0.011%
8/14/2025MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.7,071$281K0.0%-13.8%0.004%
8/14/2025Treasurer of the State of North Carolina72,587$2.87M0.0%+1.4%0.046%
8/14/2025Squarepoint Ops LLC134,395$5.31M0.0%-56.0%0.084%
8/14/2025OCONNOR A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS LLC 81,251$3.21M0.2%-10.5%0.051%
8/14/2025Daiwa Securities Group Inc.26,141$1.03M0.0%+18.1%0.016%
8/14/2025California Public Employees Retirement System201,993$7.98M0.0%+5.8%0.127%
8/13/2025Jump Financial LLC9,018$356K0.0%-88.9%0.006%
8/13/2025Tema Etfs LLC28,161$1.11M0.3%+12.0%0.018%
8/13/2025Marshall Wace LLP13,100$518K0.0%+43.9%0.008%
8/13/2025First Trust Advisors LP56,519$2.23M0.0%N/A0.035%
8/13/2025Kennedy Capital Management LLC132,045$5.22M0.1%-12.2%0.083%
8/13/2025Guggenheim Capital LLC40,857$1.61M0.0%-1.3%0.026%
8/13/2025Invesco Ltd.256,235$10.12M0.0%-89.2%0.161%
8/13/2025Granite Investment Partners LLC43,181$1.71M0.1%-36.9%0.027%
8/13/2025M&T Bank Corp7,651$303K0.0%N/A0.005%
8/13/2025Capital Counsel LLC NY50,205$1.98M0.1%+35.4%0.031%
8/13/2025Virtus Investment Advisers LLC12,476$493K0.2%+28.6%0.008%
8/13/2025Norges Bank450,254$17.79M0.0%N/A0.282%
8/13/2025Hsbc Holdings PLC108,294$4.29M0.0%+44.7%0.068%
8/13/2025Capital Fund Management S.A.31,219$1.23M0.0%-46.2%0.020%
8/13/2025Groupama Asset Managment1,160,957$45.87M0.2%+8.6%0.728%
8/13/2025State Board of Administration of Florida Retirement System153,895$6.08M0.0%+1.0%0.097%
8/13/2025Russell Investments Group Ltd.9,265$366K0.0%-97.2%0.006%
8/13/2025Rhenman & Partners Asset Management AB182,000$7.19M0.9%+124.7%0.114%
8/12/2025North Star Asset Management Inc.16,610$656K0.0%+22.0%0.010%
8/12/2025Laurel Wealth Advisors LLC23,706$937K0.0%+3,851.0%0.015%
8/12/2025Edmond DE Rothschild Holding S.A.197,600$7.81M0.1%+59.1%0.124%
8/12/2025DCF Advisers LLC91,750$3.63M1.7%-1.9%0.058%
8/12/2025Horizon Kinetics Asset Management LLC11,952$472K0.0%-4.2%0.007%
8/12/2025Prudential Financial Inc.9,254$341K0.0%+47.8%0.006%
8/12/2025American Century Companies Inc.472,749$18.68M0.0%+304.9%0.297%
8/12/2025Rhumbline Advisers181,599$7.18M0.0%-3.5%0.114%
8/12/2025Franklin Resources Inc.5,556$220K0.0%N/A0.003%
8/12/2025Legal & General Group Plc404,366$15.98M0.0%+19.5%0.254%
8/12/2025DNB Asset Management AS12,271$485K0.0%N/A0.008%
8/12/2025Entropy Technologies LP29,452$1.16M0.1%N/A0.018%
8/12/2025Swiss National Bank288,600$11.40M0.0%+4.8%0.181%
8/12/2025Westfield Capital Management Co. LP9,561$378K0.0%N/A0.006%
8/12/2025Ensign Peak Advisors Inc53,320$2.11M0.0%-3.2%0.033%
8/12/2025Artisan Partners Limited Partnership354,962$14.03M0.0%+74.7%0.223%
8/11/2025Pinnacle Wealth Planning Services Inc.5,284$209K0.0%N/A0.003%
8/11/2025Frank Rimerman Advisors LLC5,763$228K0.0%N/A0.004%
8/11/2025Raiffeisen Bank International AG56,754$2.27M0.0%+35.9%0.036%
8/11/2025Semanteon Capital Management LP9,536$377K0.6%+26.4%0.006%
8/8/2025Creative Planning53,289$2.11M0.0%+47.5%0.033%
8/8/2025Grandfield & Dodd LLC37,230$1.47M0.1%-1.4%0.023%
8/8/2025Allianz SE2,100$83K0.0%N/A0.001%
8/8/2025Candriam S.C.A.724,740$28.64M0.2%-27.1%0.455%
8/8/2025Police & Firemen s Retirement System of New Jersey59,723$2.36M0.0%+3.8%0.037%
8/8/2025Geode Capital Management LLC2,891,095$114.25M0.0%+1.7%1.814%
8/8/2025PNC Financial Services Group Inc.11,411$451K0.0%+3.9%0.007%
8/8/2025KBC Group NV4,699$186K0.0%-97.7%0.003%
8/7/2025Allworth Financial LP740$29K0.0%+231.8%0.000%
8/7/2025ProShare Advisors LLC5,943$235K0.0%-17.1%0.004%
8/7/2025Profund Advisors LLC28,859$1.14M0.0%-17.3%0.018%
8/7/2025Future Fund LLC29,595$1.17M0.5%N/A0.019%
8/7/2025Connor Clark & Lunn Investment Management Ltd.265,793$10.50M0.0%+105.6%0.167%
8/7/2025Mitsubishi UFJ Asset Management Co. Ltd.5,398$213K0.0%-12.0%0.003%
8/6/2025Fox Run Management L.L.C.10,988$434K0.1%N/A0.007%
8/6/2025Vestmark Advisory Solutions Inc.14,341$567K0.0%N/A0.009%
8/6/2025Savant Capital LLC5,607$222K0.0%N/A0.004%
8/6/2025C WorldWide Group Holding A S450,000$17.78M0.2%+12.5%0.282%
8/5/2025Huntington National Bank795$31K0.0%-27.3%0.000%
8/5/2025Corton Capital Inc.14,424$570K0.7%N/A0.009%
8/4/2025Pinnacle Associates Ltd.494,539$19.54M0.3%-18.7%0.310%
8/4/2025BLB&B Advisors LLC151,550$5.99M0.3%-0.4%0.095%
8/4/2025Amalgamated Bank11,526$455K0.0%+9.0%0.007%
(Data available from 1/1/2016 forward)

IONS Institutional Ownership - Frequently Asked Questions

Who are the largest shareholders of IONS shares?

During the previous two years, 320 institutional investors and hedge funds held shares of Ionis Pharmaceuticals. The most heavily invested institutionals were FMR LLC ($975.19M), Vanguard Group Inc. ($494.30M), T. Rowe Price Investment Management Inc. ($488.02M), Capital World Investors ($400.83M), Bellevue Group AG ($275.09M), Wellington Management Group LLP ($233.57M), and Adage Capital Partners GP L.L.C. ($150.14M).Learn more on Ionis Pharmaceuticals' institutional investors.

What percentage of Ionis Pharmaceuticals' stock is owned by institutional investors?

93.86% of Ionis Pharmaceuticals' stock is owned by institutional investors. Learn more on IONS's institutional investor holdings.

Which institutional investors have been buying Ionis Pharmaceuticals' stock?

Of the 254 institutional investors that purchased Ionis Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Adage Capital Partners GP L.L.C. ($4.59M), Wellington Management Group LLP ($3.70M), Capital World Investors ($3.64M), Norges Bank ($3.34M), T. Rowe Price Investment Management Inc. ($2.01M), BVF Inc. IL ($1.91M), and Vanguard Group Inc. ($1.42M).

How much institutional buying is happening at Ionis Pharmaceuticals?

Institutional investors have bought a total of 24,921,673 shares in the last 24 months. This purchase volume represents approximately $881.40M in transactions.

Which of Ionis Pharmaceuticals' major shareholders have been selling company stock?

Of the 122 institutional investors that sold Ionis Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: Baker BROS. Advisors LP ($30M), Readystate Asset Management LP ($11.95M), Nuveen Asset Management LLC ($9.01M), Schroder Investment Management Group ($4.83M), Jefferies Financial Group Inc. ($2.70M), Invesco Ltd. ($2.12M), and Jump Financial LLC ($2.03M).

How much institutional selling is happening at Ionis Pharmaceuticals?

Institutional investors have sold a total of 75,015,319 shares in the last 24 months. This volume of shares sold represents approximately $2.43B in transactions.


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This page (NASDAQ:IONS) was last updated on 10/10/2025 by MarketBeat.com Staff
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