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Ionis Pharmaceuticals (IONS) 10K Form and Latest SEC Filings 2026

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$44.84 -2.41 (-5.10%)
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Latest Ionis Pharmaceuticals SEC Filings & Recent Activity

Ionis Pharmaceuticals (NASDAQ:IONS) has submitted 1,083+ documents to the U.S. Securities and Exchange Commission (SEC) since 2017. For investors, these filings are the primary source of verified financial data — covering everything from annual revenue and debt levels in the 10-K, to material business events in 8-K current reports, to insider buying and selling activity in Form 4 disclosures. Key figures from these filings, including revenue, earnings, and cash flow, are summarized in Ionis Pharmaceuticals's financial statements. The most recent filing was a Form 8-K submitted on September 4, 2026.

Form 4
IONIS PHARMACEUTICALS INC Reports Ownership Change on Sep. 2, 2026

Form 4 filings disclose changes in stock ownership by company insiders, including purchases, sales, grants, and option exercises.

View insider ownership

8-K
Ionis Pharmaceuticals Files Current Report on Sep. 4, 2026

An 8-K is filed when a material corporate event occurs, such as an acquisition, leadership change, or financial update.

View filing

10-Q
Ionis Pharmaceuticals Files Quarterly Report on Apr. 29, 2026

The 10-Q contains Ionis Pharmaceuticals's unaudited quarterly financial statements, revenue, earnings updates, and cash flow changes between annual reports.

View earnings history

Ionis Pharmaceuticals SEC Filing History

Browse Ionis Pharmaceuticals' complete SEC filing history using the filters below. Filter by form type - 10-K, 10-Q, 8-K, Form 4, and more - or set a custom date range to find a filing.

DateFilerForm TypeView
09/04/2026 4:00 PM
Ionis Pharmaceuticals (874015) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
09/04/2026 5:01 AM
Ionis Pharmaceuticals (874015) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
09/02/2026 7:32 PM
BENNETT C FRANK (1073387) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
09/02/2026 7:22 PM
Birchler Brian (1970151) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
09/02/2026 7:22 PM
Ionis Pharmaceuticals (874015) Issuer
Monia Brett P (1537529) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
09/02/2026 7:22 PM
Ionis Pharmaceuticals (874015) Issuer
O'NEIL PATRICK R. (1564926) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
07/31/2026 3:42 PM
Hayden Michael R (1352908) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
07/31/2026 12:57 PM
Ionis Pharmaceuticals (874015) Filer
Form S-8
Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans  
07/17/2026 4:12 PM
BERTHELSEN SPENCER R (1181548) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
07/17/2026 4:12 PM
HERMAN JOAN E (1248398) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
07/17/2026 4:13 PM
HANTSON LUDWIG (1491435) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
07/17/2026 4:13 PM
Ionis Pharmaceuticals (874015) Issuer
Reikes Peter N (1753652) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
07/09/2026 8:03 PM
Ionis Pharmaceuticals (874015) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
07/09/2026 6:26 PM
BENNETT C FRANK (1073387) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
07/09/2026 5:07 PM
Ionis Pharmaceuticals (874015) Issuer
Kordasiewicz Holly B. (2102721) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
07/09/2026 5:07 PM
Diaz Allene M. (1773314) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
07/09/2026 1:55 PM
Ionis Pharmaceuticals (874015) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
07/07/2026 3:28 PM
BENNETT C FRANK (1073387) Reporting
Ionis Pharmaceuticals (874015) Subject
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
07/07/2026 3:30 PM
Ionis Pharmaceuticals (874015) Subject
Kordasiewicz Holly B. (2102721) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
07/07/2026 3:33 PM
Diaz Allene M. (1773314) Reporting
Ionis Pharmaceuticals (874015) Subject
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
07/06/2026 5:44 PM
BERTHELSEN SPENCER R (1181548) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
07/06/2026 5:44 PM
Diaz Allene M. (1773314) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
07/06/2026 5:45 PM
Hayden Michael R (1352908) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
07/06/2026 5:49 PM
Ionis Pharmaceuticals (874015) Issuer
KLEIN JOSEPH III (1206369) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
07/06/2026 5:49 PM
HERMAN JOAN E (1248398) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
07/06/2026 5:50 PM
Ionis Pharmaceuticals (874015) Issuer
LOSCALZO JOSEPH (1276128) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
07/06/2026 5:50 PM
Ionis Pharmaceuticals (874015) Issuer
YANG MICHAEL J. (1702283) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
07/01/2026 4:29 PM
Ionis Pharmaceuticals (874015) Subject
KLEIN JOSEPH III (1206369) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
06/30/2026 4:48 PM
Ionis Pharmaceuticals (874015) Issuer
Schneider Eugene (1838539) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
06/30/2026 4:48 PM
Ionis Pharmaceuticals (874015) Issuer
O'NEIL PATRICK R. (1564926) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
06/30/2026 4:48 PM
Baroldi Joseph (1813775) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
06/26/2026 6:09 PM
Ionis Pharmaceuticals (874015) Issuer
Swayze Eric (1791058) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
06/26/2026 6:09 PM
Ionis Pharmaceuticals (874015) Issuer
Monia Brett P (1537529) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
06/26/2026 4:43 PM
Ionis Pharmaceuticals (874015) Subject
Schneider Eugene (1838539) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
06/26/2026 4:47 PM
Ionis Pharmaceuticals (874015) Subject
O'NEIL PATRICK R. (1564926) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
06/26/2026 4:48 PM
Baroldi Mariana (1961885) Reporting
Ionis Pharmaceuticals (874015) Subject
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
06/25/2026 5:53 PM
Ionis Pharmaceuticals (874015) Subject
Swayze Eric (1791058) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
06/24/2026 2:48 PM
Ionis Pharmaceuticals (874015) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
06/16/2026 4:26 PM
BERTHELSEN SPENCER R (1181548) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
06/16/2026 4:26 PM
Ionis Pharmaceuticals (874015) Issuer
Kordasiewicz Holly B. (2102721) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
06/15/2026 9:17 AM
BERTHELSEN SPENCER R (1181548) Reporting
Ionis Pharmaceuticals (874015) Subject
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
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06/12/2026 1:20 PM
Ionis Pharmaceuticals (874015) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
06/08/2026 3:58 PM
HANTSON LUDWIG (1491435) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 3
Initial statement of beneficial ownership of securities  
06/08/2026 3:59 PM
Ionis Pharmaceuticals (874015) Issuer
Reikes Peter N (1753652) Reporting
Form 3
Initial statement of beneficial ownership of securities  
06/08/2026 3:59 PM
HANTSON LUDWIG (1491435) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
06/08/2026 3:59 PM
Ionis Pharmaceuticals (874015) Issuer
Reikes Peter N (1753652) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
06/08/2026 11:49 AM
Ionis Pharmaceuticals (874015) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
06/03/2026 4:34 PM
BERTHELSEN SPENCER R (1181548) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
06/01/2026 9:47 AM
BERTHELSEN SPENCER R (1181548) Reporting
Ionis Pharmaceuticals (874015) Subject
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
05/28/2026 11:41 AM
Ionis Pharmaceuticals (874015) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
05/15/2026 5:15 PM
Ionis Pharmaceuticals (874015) Issuer
Monia Brett P (1537529) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
05/15/2026 9:06 AM
Ionis Pharmaceuticals (874015) Subject
T. Rowe Price Investment Management, Inc. (1897612) Filed by
Form SCHEDULE 13G/A
05/14/2026 12:55 PM
Capital World Investors (1422849) Filed by
Ionis Pharmaceuticals (874015) Subject
Form SCHEDULE 13G/A
05/13/2026 4:20 PM
Ionis Pharmaceuticals (874015) Subject
Monia Brett P (1537529) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
05/06/2026 4:27 PM
Ionis Pharmaceuticals (874015) Issuer
LOSCALZO JOSEPH (1276128) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
05/04/2026 5:05 PM
Ionis Pharmaceuticals (874015) Subject
LOSCALZO JOSEPH (1276128) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
04/30/2026 3:21 PM
Baroldi Joseph (1813775) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
04/30/2026 10:07 AM
Ionis Pharmaceuticals (874015) Subject
VANGUARD CAPITAL MANAGEMENT LLC (2100119) Filed by
Form SCHEDULE 13G
04/29/2026 1:33 PM
Ionis Pharmaceuticals (874015) Filer
Form 10-Q
General form for quarterly reports under Section 13 or 15(d)  
04/29/2026 6:00 AM
Ionis Pharmaceuticals (874015) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
04/23/2026 3:22 PM
Ionis Pharmaceuticals (874015) Filer
Form DEFA14A
04/23/2026 3:24 PM
Ionis Pharmaceuticals (874015) Filer
Form ARS
04/23/2026 3:21 PM
Ionis Pharmaceuticals (874015) Filer
Form DEF 14A
04/21/2026 6:00 AM
Ionis Pharmaceuticals (874015) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
04/17/2026 6:19 PM
Baroldi Joseph (1813775) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
04/17/2026 6:19 PM
Birchler Brian (1970151) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
04/17/2026 6:19 PM
Ionis Pharmaceuticals (874015) Issuer
Jenne Kyle (1791857) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
04/17/2026 6:19 PM
Ionis Pharmaceuticals (874015) Issuer
PARSHALL B LYNNE (1073385) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
04/16/2026 5:45 PM
Baroldi Joseph (1813775) Reporting
Ionis Pharmaceuticals (874015) Subject
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
04/16/2026 5:47 PM
Birchler Brian (1970151) Reporting
Ionis Pharmaceuticals (874015) Subject
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
04/16/2026 5:49 PM
Ionis Pharmaceuticals (874015) Subject
Jenne Kyle (1791857) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
04/02/2026 6:43 PM
Devers Shannon L. (2037721) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
04/02/2026 6:43 PM
Ionis Pharmaceuticals (874015) Issuer
KLEIN JOSEPH III (1206369) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
03/31/2026 4:28 PM
Diaz Allene M. (1773314) Reporting
Ionis Pharmaceuticals (874015) Subject
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
03/27/2026 8:52 AM
Ionis Pharmaceuticals (874015) Subject
VANGUARD GROUP INC (102909) Filed by
Form SCHEDULE 13G/A
03/24/2026 3:43 PM
Ionis Pharmaceuticals (874015) Subject
Schneider Eugene (1838539) Reporting
Form 144/A
03/23/2026 6:36 PM
Ionis Pharmaceuticals (874015) Issuer
Schneider Eugene (1838539) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
03/19/2026 3:01 PM
Ionis Pharmaceuticals (874015) Subject
Schneider Eugene (1838539) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
03/09/2026 3:16 PM
Ionis Pharmaceuticals (874015) Subject
O'NEIL PATRICK R. (1564926) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
03/09/2026 6:00 AM
Ionis Pharmaceuticals (874015) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
03/05/2026 5:13 PM
Baroldi Joseph (1813775) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
03/05/2026 5:13 PM
BENNETT C FRANK (1073387) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
03/05/2026 5:14 PM
Devers Shannon L. (2037721) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
03/05/2026 5:14 PM
Diaz Allene M. (1773314) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
03/05/2026 5:14 PM
Ionis Pharmaceuticals (874015) Issuer
KLEIN JOSEPH III (1206369) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
03/05/2026 5:14 PM
Ionis Pharmaceuticals (874015) Issuer
LOSCALZO JOSEPH (1276128) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
03/03/2026 4:34 PM
Devers Shannon L. (2037721) Reporting
Ionis Pharmaceuticals (874015) Subject
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
03/03/2026 4:35 PM
Ionis Pharmaceuticals (874015) Subject
KLEIN JOSEPH III (1206369) Reporting
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
03/03/2026 4:42 PM
Baroldi Joseph (1813775) Reporting
Ionis Pharmaceuticals (874015) Subject
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
03/03/2026 4:43 PM
Baroldi Mariana (1961885) Reporting
Ionis Pharmaceuticals (874015) Subject
Form 144
Notice of proposed sale of securities pursuant to Rule 144  
02/25/2026 6:00 AM
Ionis Pharmaceuticals (874015) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
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02/17/2026 9:28 AM
Ionis Pharmaceuticals (874015) Subject
T. Rowe Price Investment Management, Inc. (1897612) Filed by
Form SCHEDULE 13G/A
02/13/2026 6:40 PM
Ionis Pharmaceuticals (874015) Issuer
PARSHALL B LYNNE (1073385) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
02/13/2026 6:40 PM
Ionis Pharmaceuticals (874015) Issuer
Swayze Eric (1791058) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
02/13/2026 6:40 PM
BENNETT C FRANK (1073387) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4/A
02/04/2026 3:06 PM
BENNETT C FRANK (1073387) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
02/02/2026 7:51 PM
Baroldi Joseph (1813775) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
02/02/2026 7:51 PM
BENNETT C FRANK (1073387) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
02/02/2026 7:51 PM
Birchler Brian (1970151) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
02/02/2026 7:51 PM
HOUGEN ELIZABETH L (1074773) Reporting
Ionis Pharmaceuticals (874015) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
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Ionis Pharmaceuticals SEC Filings - Frequently Asked Questions

Ionis Pharmaceuticals (IONS) has submitted 1,083+ filings to the SEC since 2017. You can browse the complete history or filter by form type using the tools above.

Ionis Pharmaceuticals's fiscal year ends on December 31. The company typically files its 10-K annual report by the end of February, covering the prior fiscal year's financial results. Key financial data from these reports is available on Ionis Pharmaceuticals's financial statements page.

The most recent filing was a Form 8-K submitted on September 4, 2026. This was a current report on a material business event.

SEC Filing Types: 10-K, 10-Q, 8-K and More

SEC filings are legally required disclosures that public companies submit to the U.S. Securities and Exchange Commission. Unlike press releases or earnings call transcripts, these documents are filed under legal obligation — meaning the financial data they contain is audited, standardized, and subject to penalties if materially false. For investors, that makes SEC filings the most reliable primary source available for evaluating a company's true financial position.

Yes. All SEC filings are publicly available through the SEC's EDGAR database and on financial research platforms like MarketBeat. Companies are required by law to make these disclosures accessible to all investors — meaning retail investors have access to the same source documents as institutional analysts.

A 10-K is an annual report containing audited financial statements and a full review of the company's business — it is the most comprehensive filing a company makes each year. A 10-Q is a shorter, unaudited quarterly update filed three times per year between annual reports. Investors typically use the 10-K for deep fundamental analysis and the 10-Q to track whether the company is on pace with its guidance mid-year.

The most important filing for fundamental investors. Filed once per year, the 10-K contains audited financial statements, revenue and earnings trends, debt obligations, risk factors, and management's own assessment of the business. Reading the risk factors section and comparing year-over-year financials can reveal issues that don't show up in analyst summaries.

An unaudited financial update filed three times per year (the 10-K covers Q4). Investors use 10-Qs to track whether guidance is on pace, monitor changes in cash flow or inventory, and catch any mid-year shifts in business conditions before they become headline news.

Filed within four business days of a material event — earnings releases, merger announcements, executive departures, or major asset sales. Because 8-Ks are filed before media coverage catches up, they are often the fastest way to get unfiltered information directly from the company on market-moving events.

Filed within two business days whenever an executive or director buys or sells company stock. Insider purchases — especially large or clustered buys — are often interpreted as a signal of management confidence. Insider selling is more ambiguous but worth monitoring for patterns, particularly around lock-up expirations or ahead of major announcements.


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SEC filings for NASDAQ:IONS are sourced directly from the U.S. Securities and Exchange Commission (SEC), with the most recent filing dated 9/4/2026. New filings are added as they're published.
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