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Ionis Pharmaceuticals (IONS) Institutional Ownership

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$56.71 -1.38 (-2.38%)
Closing price 09/8/2026 04:00 PM Eastern
Extended Trading
$56.40 -0.31 (-0.54%)
As of 05:41 AM Eastern
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Institutional Ownership Changes (13F Filings) for Ionis Pharmaceuticals (NASDAQ:IONS)

Current
Institutional Ownership
Percentage
93.86%
Number of
Institutional Buyers
(last 12 months)
278
Total
Institutional Inflows
(last 12 months)
$3.63B
Number of
Institutional Sellers
(last 12 months)
141
Total
Institutional Outflows
(last 12 months)
$2.86B
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IONS Institutional Buying and Selling by Quarter

Ionis Pharmaceuticals Major Shareholders & Ownership History

Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
9/9/2026 NewEdge Advisors LLC4,822$382K0.0%-77.9%0.003%
9/9/2026 Squarepoint Ops LLC109,379$8.67M0.0%-84.3%0.066%
9/8/2026 Arizona State Retirement System43,302$3.43M0.0%+2.5%0.026%
9/8/2026 Carmignac Gestion321,000$25.45M0.3%+505.7%0.193%
9/8/2026 Nykredit A S6,154$488K0.0%N/A0.004%
8/26/2026 HighTower Advisors LLC4,084$324K0.0%+7.6%0.002%
8/25/2026 VIRGINIA RETIREMENT SYSTEMS ET Al13,400$1.06M0.0%N/A0.008%
8/24/2026 California State Teachers Retirement System14,347,446$1.14B0.0%+8,029.6%8.634%
8/22/2026 AlphaGrep UK Ltd2,946$234K0.1%N/A0.002%
8/21/2026 AXQ Capital LP10,423$826K0.1%+171.0%0.006%
8/21/2026 Braidwell LP116,762$9.26M0.3%-10.8%0.070%
8/21/2026 Nykredit A S6,154$488K0.0%N/A0.004%
8/20/2026 Ancora Advisors LLC2,215$176K0.0%-7.4%0.001%
8/20/2026 Alyeska Investment Group L.P.1,417,916$112.43M0.3%+199.7%0.853%
8/20/2026 Northwestern Mutual Wealth Management Co.10,925$866K0.0%-1.8%0.007%
8/19/2026 Van ECK Associates Corp63,396$5.03M0.0%+83.7%0.038%
8/19/2026 Hsbc Holdings PLC188,402$15.05M0.0%+1.3%0.113%
8/19/2026 Archer Investment Corp600$48K0.0%N/A0.000%
8/18/2026 North Star Asset Management Inc.16,560$1.31M0.1%N/A0.010%
8/18/2026 Empowered Funds LLC223,142$17.69M0.1%N/A0.134%
8/18/2026Jefferies Financial Group Inc.38,665$3.07M0.0%N/A0.023%
8/18/2026 Public Employees Retirement System of Ohio46,862$3.72M0.0%N/A0.028%
8/17/2026 Corient Private Wealth LP196,791$15.60M0.0%N/A0.118%
8/17/2026 Artia Global Partners LP144,376$11.45M2.1%N/A0.087%
8/17/2026 Bamco Inc. NY14,000$1.11M0.0%N/A0.008%
8/17/2026 Bank of America Corp DE790,990$62.72M0.0%N/A0.476%
8/17/2026 Boone Capital Management LLC519,977$41.23M9.6%N/A0.313%
8/15/2026 Freestone Grove Partners LP339,967$26.96M0.2%N/A0.205%
8/15/2026 Jupiter Topco LLC68,191$5.41M0.0%N/A0.041%
8/14/2026 ADAR1 Capital Management LLC166,286$13.19M0.6%N/A0.100%
8/14/2026 Hsbc Holdings PLC188,402$15.05M0.0%N/A0.113%
8/14/2026 EFG International AG122,804$9.74M0.2%N/A0.074%
8/14/2026 Ancora Advisors LLC2,215$176K0.0%N/A0.001%
8/14/2026 Canada Pension Plan Investment Board33,300$2.64M0.0%N/A0.020%
8/14/2026 Legal & General Group Plc299,184$23.72M0.0%N/A0.180%
8/14/2026 The Manufacturers Life Insurance Company120,678$9.57M0.0%N/A0.073%
8/14/2026 Algert Global LLC206,853$16.40M0.2%+77.5%0.124%
8/13/2026 Sanctuary Advisors LLC3,938$312K0.0%N/A0.002%
8/13/2026 Polymer Capital Management HK LTD177,897$14.11M0.7%N/A0.107%
8/13/2026 Connor Clark & Lunn Investment Management Ltd.684,236$54.25M0.1%N/A0.412%
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8/13/2026 Bank of Nova Scotia68,548$5.44M0.0%N/A0.041%
8/12/2026 Commerce Bank11,681$926K0.0%N/A0.007%
8/12/2026 Northwestern Mutual Wealth Management Co.10,925$866K0.0%N/A0.007%
8/12/2026 Quantbot Technologies LP4,812$382K0.0%N/A0.003%
8/12/2026 Evolve Private Wealth LLC10,653$845K0.1%N/A0.006%
8/12/2026 Callan Family Office LLC7,143$566K0.0%N/A0.004%
8/11/2026 Allworth Financial LP516$41K0.0%N/A0.000%
8/11/2026 Silvant Capital Management LLC540$43K0.0%N/A0.000%
8/11/2026 E Fund Management Co. Ltd.5,569$442K0.0%N/A0.003%
8/11/2026 Edmond DE Rothschild Holding S.A.113,320$8.99M0.1%N/A0.068%
8/10/2026 DCF Advisers LLC37,500$2.97M0.5%N/A0.023%
8/10/2026 NewEdge Wealth LLC8,977$712K0.0%N/A0.005%
8/10/2026 Eagle Health Investments LP194,577$15.43M2.6%N/A0.117%
8/10/2026 Great Lakes Advisors LLC66,924$5.31M0.0%N/A0.040%
8/8/2026 Meeder Advisory Services Inc.7,660$607K0.0%N/A0.005%
8/7/2026 Grandfield & Dodd LLC37,077$2.94M0.2%N/A0.022%
8/7/2026 Deutsche Bank AG169,614$13.45M0.0%N/A0.102%
8/7/2026 Perigon Wealth Management LLC3,477$276K0.0%N/A0.002%
8/7/2026 TimesSquare Capital Management LLC614,070$48.69M0.7%N/A0.370%
8/7/2026 Mitsubishi UFJ Asset Management Co. Ltd.2,618$208K0.0%N/A0.002%
8/7/2026 OneDigital Investment Advisors LLC5,345$424K0.0%N/A0.003%
8/6/2026 Global Retirement Partners LLC2,282$181K0.0%N/A0.001%
8/6/2026 Bank of New York Mellon Corp542,454$43.01M0.0%N/A0.326%
8/6/2026 State of Wyoming2,024$160K0.0%N/A0.001%
8/6/2026 GSA Capital Partners LLP17,306$1.37M0.1%N/A0.010%
7/10/2026 Handelsbanken Fonder AB383,211$30.39M0.1%+79.1%0.232%
7/8/2026 Victrix Investment Advisors3,400$270K0.1%N/A0.002%
7/8/2026 Assenagon Asset Management S.A.40,927$3.25M0.0%+21.5%0.025%
7/7/2026 GAMMA Investing LLC2,168$172K0.0%+22.8%0.001%
7/7/2026 Harbor Investment Advisory LLC1,407$112K0.0%N/A0.001%
6/16/2026 Empowered Funds LLC103,141$7.75M0.0%+318.1%0.062%
6/15/2026 Carmignac Gestion53,000$3.98M0.1%N/A0.032%
5/29/2026 Perceptive Advisors LLC504,000$37.85M0.7%N/A0.305%
5/22/2026 Groupama Asset Managment824,540$61.92M0.9%+7.5%0.499%
5/19/2026 Stempoint Capital LP26,385$1.98M0.4%N/A0.016%
5/19/2026 Edgestream Partners L.P.68,369$5.13M0.2%N/A0.041%
5/18/2026 ADAR1 Capital Management LLC160,338$12.04M0.7%+9.0%0.097%
5/18/2026 EverSource Wealth Advisors LLC1,794$135K0.0%+57.8%0.001%
5/18/2026 California State Teachers Retirement System176,485$13.25M0.0%+22.4%0.107%
5/18/2026 Readystate Asset Management LP20,436$1.54M0.1%N/A0.012%
5/18/2026 Empowered Funds LLC103,141$7.75M0.0%+318.1%0.062%
5/18/2026 Eversept Partners LP632,100$47.46M2.5%+17.4%0.382%
5/18/2026 Exome Asset Management LLC110,064$8.27M4.3%-5.5%0.067%
5/16/2026 The Manufacturers Life Insurance Company149,538$11.23M0.0%-2.4%0.090%
5/16/2026 Quantinno Capital Management LP55,502$4.17M0.0%+17.1%0.034%
5/15/2026 Entropy Technologies LP27,207$2.04M0.1%N/A0.016%
5/14/2026 Renaissance Technologies LLC305,549$22.94M0.0%+36.6%0.185%
5/14/2026 Public Employees Retirement System of Ohio46,030$3.46M0.0%-3.3%0.028%
5/14/2026 Arrowstreet Capital Limited Partnership737,859$55.41M0.0%-30.6%0.446%
5/14/2026 Inceptionr LLC16,821$1.26M0.3%-5.8%0.010%
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5/13/2026 Cetera Investment Advisers11,280$847K0.0%+3.9%0.007%
5/13/2026 First Trust Advisors LP468,363$35.17M0.0%-10.8%0.283%
5/8/2026 PNC Financial Services Group Inc.13,545$1.02M0.0%-2.0%0.008%
5/8/2026 Cassaday & Co Wealth Management LLC400$30K0.0%N/A0.000%
5/8/2026 Amova Asset Management Americas Inc.81,696$6.13M0.1%-12.7%0.049%
5/7/2026 Florida Financial Advisors LLC25,886$1.94M0.5%N/A0.016%
5/7/2026 Dimensional Fund Advisors LP267,215$20.06M0.0%+51.8%0.162%
5/7/2026 AlphaCentric Advisors LLC19,587$1.47M1.5%+5.7%0.012%
5/7/2026 KBC Group NV30,213$2.27M0.0%+233.8%0.018%
5/7/2026 SEB Asset Management AB114,334$8.59M0.0%N/A0.069%


IONS Institutional Ownership - Frequently Asked Questions

During the previous two years, 438 institutional investors and hedge funds held shares of Ionis Pharmaceuticals. The most heavily invested institutionals were Capital World Investors ($1.42B), Vanguard Group Inc. ($1.30B), California State Teachers Retirement System ($1.14B), T. Rowe Price Investment Management Inc. ($720.54M), Bellevue Group AG ($408.51M), Geode Capital Management LLC ($249.16M), and Deep Track Capital LP ($249.13M).Learn more on Ionis Pharmaceuticals' institutional investors.

93.86% of Ionis Pharmaceuticals' stock is owned by institutional investors. Learn more on IONS's institutional investor holdings.

Of the 386 institutional investors that purchased Ionis Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: California State Teachers Retirement System ($14.22M), Capital World Investors ($9.06M), Adage Capital Partners GP L.L.C. ($3.53M), Norges Bank ($2.49M), Baker BROS. Advisors LP ($2.02M), T. Rowe Price Investment Management Inc. ($2.01M), and BVF Inc. IL ($1.91M).

Institutional investors have bought a total of 47,403,857 shares in the last 24 months. This purchase volume represents approximately $3.63B in transactions.

Of the 141 institutional investors that sold Ionis Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: T. Rowe Price Investment Management Inc. ($11.42M), New York State Common Retirement Fund ($8.03M), Amundi ($3.20M), Millennium Management LLC ($1.87M), Bellevue Group AG ($1.61M), Jefferies Financial Group Inc. ($1.22M), and Adage Capital Partners GP L.L.C. ($1.18M).

Institutional investors have sold a total of 39,774,538 shares in the last 24 months. This volume of shares sold represents approximately $2.86B in transactions.



Institutional ownership data for NASDAQ:IONS is compiled from quarterly 13F filings submitted to the U.S. Securities and Exchange Commission (SEC), with the most recent received on 9/9/2026. New 13F filings are added each quarter as they're published.
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