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Ionis Pharmaceuticals (IONS) Institutional Ownership

Ionis Pharmaceuticals logo
$45.57 +1.07 (+2.40%)
Closing price 09/28/2026 04:00 PM Eastern
Extended Trading
$45.78 +0.21 (+0.47%)
As of 09:02 AM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.
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Institutional Ownership Changes (13F Filings) for Ionis Pharmaceuticals (NASDAQ:IONS)

Current
Institutional Ownership
Percentage
93.86%
Number of
Institutional Buyers
(last 12 months)
282
Total
Institutional Inflows
(last 12 months)
$2.50B
Number of
Institutional Sellers
(last 12 months)
141
Total
Institutional Outflows
(last 12 months)
$2.87B
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IONS Institutional Buying and Selling by Quarter

Ionis Pharmaceuticals Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
9/9/2026Sequoia Financial Advisors LLC3,567$283K0.0%N/A0.002%
9/9/2026Tidal Investments LLC49,178$3.90M0.0%+42.8%0.030%
9/9/2026MCF Advisors LLC6,136$487K0.0%+12,172.0%0.004%
9/9/2026Engineers Gate Manager LP14,840$1.18M0.0%-88.9%0.009%
9/9/2026Integrated Wealth Concepts LLC2,926$232K0.0%+7.4%0.002%
9/9/2026NewEdge Advisors LLC4,822$382K0.0%-77.9%0.003%
9/9/2026Squarepoint Ops LLC109,379$8.67M0.0%-84.3%0.066%
9/8/2026Arizona State Retirement System43,302$3.43M0.0%+2.5%0.026%
9/8/2026Carmignac Gestion321,000$25.45M0.3%+505.7%0.193%
9/8/2026Nykredit A S6,154$488K0.0%N/A0.004%
8/26/2026HighTower Advisors LLC4,084$324K0.0%+7.6%0.002%
8/25/2026VIRGINIA RETIREMENT SYSTEMS ET Al13,400$1.06M0.0%N/A0.008%
8/22/2026AlphaGrep UK Ltd2,946$234K0.1%N/A0.002%
8/21/2026AXQ Capital LP10,423$826K0.1%+171.0%0.006%
8/21/2026Braidwell LP116,762$9.26M0.3%-10.8%0.070%
8/21/2026Nykredit A S6,154$488K0.0%N/A0.004%
8/20/2026Ancora Advisors LLC2,215$176K0.0%-7.4%0.001%
8/20/2026Alyeska Investment Group L.P.1,417,916$112.43M0.3%+199.7%0.853%
8/20/2026Northwestern Mutual Wealth Management Co.10,925$866K0.0%-1.8%0.007%
8/19/2026Van ECK Associates Corp63,396$5.03M0.0%+83.7%0.038%
8/19/2026Hsbc Holdings PLC188,402$15.05M0.0%+1.3%0.113%
8/19/2026Archer Investment Corp600$48K0.0%N/A0.000%
8/18/2026North Star Asset Management Inc.16,560$1.31M0.1%N/A0.010%
8/18/2026Empowered Funds LLC223,142$17.69M0.1%N/A0.134%
8/18/2026Jefferies Financial Group Inc.38,665$3.07M0.0%N/A0.023%
8/18/2026Public Employees Retirement System of Ohio46,862$3.72M0.0%N/A0.028%
8/17/2026Corient Private Wealth LP196,791$15.60M0.0%N/A0.118%
8/17/2026Artia Global Partners LP144,376$11.45M2.1%N/A0.087%
8/17/2026Bamco Inc. NY14,000$1.11M0.0%N/A0.008%
8/17/2026Bank of America Corp DE790,990$62.72M0.0%N/A0.476%
8/17/2026Boone Capital Management LLC519,977$41.23M9.6%N/A0.313%
8/15/2026Freestone Grove Partners LP339,967$26.96M0.2%N/A0.205%
8/15/2026Jupiter Topco LLC68,191$5.41M0.0%N/A0.041%
8/14/2026ADAR1 Capital Management LLC166,286$13.19M0.6%N/A0.100%
8/14/2026Hsbc Holdings PLC188,402$15.05M0.0%N/A0.113%
8/14/2026EFG International AG122,804$9.74M0.2%N/A0.074%
8/14/2026Ancora Advisors LLC2,215$176K0.0%N/A0.001%
8/14/2026Canada Pension Plan Investment Board33,300$2.64M0.0%N/A0.020%
8/14/2026Legal & General Group Plc299,184$23.72M0.0%N/A0.180%
8/14/2026The Manufacturers Life Insurance Company120,678$9.57M0.0%N/A0.073%
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8/14/2026Algert Global LLC206,853$16.40M0.2%+77.5%0.124%
8/13/2026Sanctuary Advisors LLC3,938$312K0.0%N/A0.002%
8/13/2026Polymer Capital Management HK LTD177,897$14.11M0.7%N/A0.107%
8/13/2026Connor Clark & Lunn Investment Management Ltd.684,236$54.25M0.1%N/A0.412%
8/13/2026Bank of Nova Scotia68,548$5.44M0.0%N/A0.041%
8/12/2026Commerce Bank11,681$926K0.0%N/A0.007%
8/12/2026Northwestern Mutual Wealth Management Co.10,925$866K0.0%N/A0.007%
8/12/2026Quantbot Technologies LP4,812$382K0.0%N/A0.003%
8/12/2026Evolve Private Wealth LLC10,653$845K0.1%N/A0.006%
8/12/2026Callan Family Office LLC7,143$566K0.0%N/A0.004%
8/11/2026Allworth Financial LP516$41K0.0%N/A0.000%
8/11/2026Silvant Capital Management LLC540$43K0.0%N/A0.000%
8/11/2026E Fund Management Co. Ltd.5,569$442K0.0%N/A0.003%
8/11/2026Edmond DE Rothschild Holding S.A.113,320$8.99M0.1%N/A0.068%
8/10/2026DCF Advisers LLC37,500$2.97M0.5%N/A0.023%
8/10/2026NewEdge Wealth LLC8,977$712K0.0%N/A0.005%
8/10/2026Eagle Health Investments LP194,577$15.43M2.6%N/A0.117%
8/10/2026Great Lakes Advisors LLC66,924$5.31M0.0%N/A0.040%
8/8/2026Meeder Advisory Services Inc.7,660$607K0.0%N/A0.005%
8/7/2026Grandfield & Dodd LLC37,077$2.94M0.2%N/A0.022%
8/7/2026Deutsche Bank AG169,614$13.45M0.0%N/A0.102%
8/7/2026Perigon Wealth Management LLC3,477$276K0.0%N/A0.002%
8/7/2026TimesSquare Capital Management LLC614,070$48.69M0.7%N/A0.370%
8/7/2026Mitsubishi UFJ Asset Management Co. Ltd.2,618$208K0.0%N/A0.002%
8/7/2026OneDigital Investment Advisors LLC5,345$424K0.0%N/A0.003%
8/6/2026Global Retirement Partners LLC2,282$181K0.0%N/A0.001%
8/6/2026Bank of New York Mellon Corp542,454$43.01M0.0%N/A0.326%
8/6/2026State of Wyoming2,024$160K0.0%N/A0.001%
8/6/2026GSA Capital Partners LLP17,306$1.37M0.1%N/A0.010%
7/10/2026Handelsbanken Fonder AB383,211$30.39M0.1%+79.1%0.232%
7/8/2026Victrix Investment Advisors3,400$270K0.1%N/A0.002%
7/8/2026Assenagon Asset Management S.A.40,927$3.25M0.0%+21.5%0.025%
7/7/2026GAMMA Investing LLC2,168$172K0.0%+22.8%0.001%
7/7/2026Harbor Investment Advisory LLC1,407$112K0.0%N/A0.001%
6/16/2026Empowered Funds LLC103,141$7.75M0.0%+318.1%0.062%
6/15/2026Carmignac Gestion53,000$3.98M0.1%N/A0.032%
5/29/2026Perceptive Advisors LLC504,000$37.85M0.7%N/A0.305%
5/22/2026Groupama Asset Managment824,540$61.92M0.9%+7.5%0.499%
5/19/2026Stempoint Capital LP26,385$1.98M0.4%N/A0.016%
5/19/2026Edgestream Partners L.P.68,369$5.13M0.2%N/A0.041%
5/18/2026ADAR1 Capital Management LLC160,338$12.04M0.7%+9.0%0.097%
5/18/2026EverSource Wealth Advisors LLC1,794$135K0.0%+57.8%0.001%
5/18/2026California State Teachers Retirement System176,485$13.25M0.0%+22.4%0.107%
5/18/2026Readystate Asset Management LP20,436$1.54M0.1%N/A0.012%
5/18/2026Empowered Funds LLC103,141$7.75M0.0%+318.1%0.062%
5/18/2026Eversept Partners LP632,100$47.46M2.5%+17.4%0.382%
5/18/2026Exome Asset Management LLC110,064$8.27M4.3%-5.5%0.067%
5/16/2026The Manufacturers Life Insurance Company149,538$11.23M0.0%-2.4%0.090%
5/16/2026Quantinno Capital Management LP55,502$4.17M0.0%+17.1%0.034%
5/15/2026Entropy Technologies LP27,207$2.04M0.1%N/A0.016%
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5/14/2026Renaissance Technologies LLC305,549$22.94M0.0%+36.6%0.185%
5/14/2026Public Employees Retirement System of Ohio46,030$3.46M0.0%-3.3%0.028%
5/14/2026Arrowstreet Capital Limited Partnership737,859$55.41M0.0%-30.6%0.446%
5/14/2026Inceptionr LLC16,821$1.26M0.3%-5.8%0.010%
5/13/2026Cetera Investment Advisers11,280$847K0.0%+3.9%0.007%
5/13/2026First Trust Advisors LP468,363$35.17M0.0%-10.8%0.283%
5/8/2026PNC Financial Services Group Inc.13,545$1.02M0.0%-2.0%0.008%
5/8/2026Cassaday & Co Wealth Management LLC400$30K0.0%N/A0.000%
5/8/2026Amova Asset Management Americas Inc.81,696$6.13M0.1%-12.7%0.049%
5/7/2026Florida Financial Advisors LLC25,886$1.94M0.5%N/A0.016%


IONS Institutional Ownership - Frequently Asked Questions

During the previous two years, 441 institutional investors and hedge funds held shares of Ionis Pharmaceuticals. The most heavily invested institutionals were Capital World Investors ($1.42B), Vanguard Group Inc. ($1.30B), T. Rowe Price Investment Management Inc. ($720.54M), Bellevue Group AG ($408.51M), Geode Capital Management LLC ($249.16M), Deep Track Capital LP ($249.13M), and Price T Rowe Associates Inc. MD ($236.37M).Learn more on Ionis Pharmaceuticals' institutional investors.

93.86% of Ionis Pharmaceuticals' stock is owned by institutional investors. Learn more on IONS's institutional investor holdings.

Of the 390 institutional investors that purchased Ionis Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Capital World Investors ($9.06M), Adage Capital Partners GP L.L.C. ($3.53M), Norges Bank ($2.49M), Baker BROS. Advisors LP ($2.02M), T. Rowe Price Investment Management Inc. ($2.01M), BVF Inc. IL ($1.91M), and Vestal Point Capital LP ($1.67M).

Institutional investors have bought a total of 33,256,790 shares in the last 24 months. This purchase volume represents approximately $2.50B in transactions.

Of the 141 institutional investors that sold Ionis Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: T. Rowe Price Investment Management Inc. ($11.42M), New York State Common Retirement Fund ($8.03M), Amundi ($3.20M), Millennium Management LLC ($1.87M), Bellevue Group AG ($1.61M), Jefferies Financial Group Inc. ($1.22M), and Adage Capital Partners GP L.L.C. ($1.18M).

Institutional investors have sold a total of 39,893,525 shares in the last 24 months. This volume of shares sold represents approximately $2.87B in transactions.


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Institutional ownership data for NASDAQ:IONS is compiled from quarterly 13F filings submitted to the U.S. Securities and Exchange Commission (SEC), with the most recent received on 9/9/2026. New 13F filings are added each quarter as they're published.
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