NASDAQ:KPTI - Karyopharm Therapeutics Stock Price, News, & Analysis Sign in or create an account to add this stock to your watchlist. Get Started $8.97 -0.36 (-3.86 %) (As of 02/21/2019 04:00 PM ET)Previous Close$9.33Today's Range$8.91 - $9.4052-Week Range$8.01 - $21.71Volume2.09 million shsAverage Volume900,601 shsMarket Capitalization$544.55 millionP/E Ratio-3.19Dividend YieldN/ABeta3.42 ProfileDiscussionAnalyst RatingsChartEarningsFinancialsInsider TradesInstitutional OwnershipHeadlinesOptions ChainSEC FilingsSocial Media Share on FacebookShare on TwitterShare on LinkedInShare on RedditShare on StocktwitsPrint this articleShare by Email Karyopharm Therapeutics Inc., a clinical-stage pharmaceutical company, focuses on the discovery, development, and commercialization of drugs directed against nuclear transport and related targets for the treatment of cancer and other diseases. Its lead drug candidate is Selinexor(KPT-330), which is in Phase 2b clinical study in treatments of refractory multiple myeloma; Phase 1b/2 clinical study in combination with backbone treatments for multiple myeloma patients; Phase 2b clinical study in diffuse large B-cell lymphoma; Phase 3 clinical trial in combination with Velcade (bortezomib) and dexamethasone for multiple myeloma patients; and Phase 2/3 clinical study in liposarcoma. The company is also developing KPT-8602 that is in Phase 1/2 study for patients with relapsed/refractory multiple myeloma; KPT-9274, which is in Phase I clinical trial for patients with advanced solid malignancies or non-Hodgkin's lymphoma; KPT-335, which is in Phase I clinical trial for the treatment of viral indications; and KPT-350 that is in preclinical stage to treat neurological disorders, and inflammatory and autoimmune diseases. Karyopharm Therapeutics Inc. was founded in 2008 and is headquartered in Newton, Massachusetts. 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Industry, Sector and Symbol Stock Exchange NASDAQ Industry Pharmaceutical preparations Sub-IndustryN/A SectorMedical Current SymbolNASDAQ:KPTI Previous Symbol CUSIPN/A CIK1503802 Webwww.karyopharm.com Phone617-658-0600Debt Debt-to-Equity RatioN/A Current Ratio5.09 Quick Ratio5.09Price-To-Earnings Trailing P/E Ratio-3.19 Forward P/E Ratio-3.02 P/E GrowthN/A Sales & Book Value Annual Sales$1.61 million Price / Sales338.23 Cash FlowN/A Price / Cash FlowN/A Book Value$2.61 per share Price / Book3.44Profitability EPS (Most Recent Fiscal Year)($2.81) Net Income$-128,980,000.00 Net Margins-502.90% Return on Equity-104.50% Return on Assets-79.30%Miscellaneous Employees154 Outstanding Shares60,708,000Market Cap$544.55 million Next Earnings Date3/21/2019 (Estimated) OptionableOptionable Karyopharm Therapeutics (NASDAQ:KPTI) Frequently Asked Questions What is Karyopharm Therapeutics' stock symbol? Karyopharm Therapeutics trades on the NASDAQ under the ticker symbol "KPTI." How were Karyopharm Therapeutics' earnings last quarter? Karyopharm Therapeutics Inc (NASDAQ:KPTI) issued its quarterly earnings results on Tuesday, August, 7th. The company reported ($0.60) earnings per share for the quarter, beating the consensus estimate of ($0.81) by $0.21. The company earned $19.89 million during the quarter, compared to analysts' expectations of $5.97 million. Karyopharm Therapeutics had a negative return on equity of 104.50% and a negative net margin of 502.90%. View Karyopharm Therapeutics' Earnings History. When is Karyopharm Therapeutics' next earnings date? Karyopharm Therapeutics is scheduled to release their next quarterly earnings announcement on Thursday, March 21st 2019. View Earnings Estimates for Karyopharm Therapeutics. What price target have analysts set for KPTI? 11 brokerages have issued twelve-month price targets for Karyopharm Therapeutics' stock. Their forecasts range from $18.00 to $30.00. On average, they expect Karyopharm Therapeutics' stock price to reach $23.1111 in the next year. This suggests a possible upside of 157.6% from the stock's current price. View Analyst Price Targets for Karyopharm Therapeutics. What is the consensus analysts' recommendation for Karyopharm Therapeutics? 11 Wall Street analysts have issued "buy," "hold," and "sell" ratings for Karyopharm Therapeutics in the last year. There are currently 1 hold rating and 10 buy ratings for the stock, resulting in a consensus recommendation of "Buy." View Analyst Ratings for Karyopharm Therapeutics. What are Wall Street analysts saying about Karyopharm Therapeutics stock? Here are some recent quotes from research analysts about Karyopharm Therapeutics stock: 1. According to Zacks Investment Research, "Karyopharm Therapeutics, Inc. is a clinical-stage pharmaceutical company focused on the discovery and development of drugs for the treatment of cancer and other major diseases. It serves the healthcare industry throughout the United States. Karyopharm Therapeutics, Inc. is based in United States. " (2/2/2019) 2. HC Wainwright analysts commented, "We continue to believe that selinexor could be approved for use in r/ r DLBCL patients, and we are encouraged by the data." (12/3/2018) Has Karyopharm Therapeutics been receiving favorable news coverage? Press coverage about KPTI stock has been trending somewhat positive on Thursday, according to InfoTrie. InfoTrie scores the sentiment of news coverage by reviewing more than six thousand blog and news sources. The firm ranks coverage of publicly-traded companies on a scale of negative five to five, with scores nearest to five being the most favorable. Karyopharm Therapeutics earned a media sentiment score of 0.6 on InfoTrie's scale. They also gave headlines about the company a news buzz of 1.0 out of 10, indicating that recent news coverage is extremely unlikely to have an effect on the stock's share price in the near future. Who are some of Karyopharm Therapeutics' key competitors? Some companies that are related to Karyopharm Therapeutics include Ironwood Pharmaceuticals (IRWD), Akcea Therapeutics (AKCA), Heron Therapeutics (HRTX), Amicus Therapeutics (FOLD), Portola Pharmaceuticals (PTLA), Madrigal Pharmaceuticals (MDGL), Zogenix (ZGNX), Endocyte (ECYT), Enanta Pharmaceuticals (ENTA), Supernus Pharmaceuticals (SUPN), Insmed (INSM), Xencor (XNCR), The Medicines (MDCO), PTC Therapeutics (PTCT) and Biohaven Pharmaceutical (BHVN). What other stocks do shareholders of Karyopharm Therapeutics own? Based on aggregate information from My MarketBeat watchlists, some companies that other Karyopharm Therapeutics investors own include Gilead Sciences (GILD), Celgene (CELG), Caladrius Biosciences (CLBS), Progenics Pharmaceuticals (PGNX), Exelixis (EXEL), Alibaba Group (BABA), Verastem (VSTM), Intercept Pharmaceuticals (ICPT), Synergy Pharmaceuticals (SGYP) and GW Pharmaceuticals PLC- (GWPH). Who are Karyopharm Therapeutics' key executives? Karyopharm Therapeutics' management team includes the folowing people: Dr. Michael G. Kauffman, Co-Founder, CEO & Director (Age 56)Dr. Sharon Shacham, Co-Founder, Pres, Chief Scientific Officer & Co-Chairman of Scientific Advisory Board (Age 49)Mr. Christopher Brett Primiano, Exec. VP, Chief Bus. Officer, Gen. Counsel & Sec. (Age 38)Dr. Mansoor Raza Mirza, Clinical Consultant, Member of Scientific Advisory Board & Director (Age 58)Mr. Cameron Peters, Principal Financial & Accounting Officer (Age 59) Who are Karyopharm Therapeutics' major shareholders? Karyopharm Therapeutics' stock is owned by many different of institutional and retail investors. Top institutional investors include BlackRock Inc. (7.01%), Ridgeback Capital Investments L.P. (6.50%), Candriam Luxembourg S.C.A. (2.95%), Emerald Advisers LLC (2.40%), Emerald Mutual Fund Advisers Trust (2.26%) and Dimensional Fund Advisors LP (1.11%). Company insiders that own Karyopharm Therapeutics stock include Christopher Brett Primiano, Ltd Chione, Mansoor Raza Mirza, Michael Kauffman and Sharon Shacham. View Institutional Ownership Trends for Karyopharm Therapeutics. Which institutional investors are selling Karyopharm Therapeutics stock? KPTI stock was sold by a variety of institutional investors in the last quarter, including Millennium Management LLC, Barclays PLC, D. E. Shaw & Co. Inc., Frontier Capital Management Co. LLC, Private Capital Advisors Inc., Northern Trust Corp, MetLife Investment Advisors LLC and Bank of America Corp DE. Company insiders that have sold Karyopharm Therapeutics company stock in the last year include Christopher Brett Primiano, Ltd Chione, Mansoor Raza Mirza, Michael Kauffman and Sharon Shacham. View Insider Buying and Selling for Karyopharm Therapeutics. Which institutional investors are buying Karyopharm Therapeutics stock? KPTI stock was acquired by a variety of institutional investors in the last quarter, including Ridgeback Capital Investments L.P., Emerald Advisers LLC, Emerald Mutual Fund Advisers Trust, Candriam Luxembourg S.C.A., Dimensional Fund Advisors LP, Two Sigma Investments LP, First Midwest Bank Trust Division and First Trust Advisors LP. View Insider Buying and Selling for Karyopharm Therapeutics. How do I buy shares of Karyopharm Therapeutics? Shares of KPTI can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Vanguard Brokerage Services, TD Ameritrade, E*TRADE, Scottrade, Fidelity and Charles Schwab. What is Karyopharm Therapeutics' stock price today? One share of KPTI stock can currently be purchased for approximately $8.97. How big of a company is Karyopharm Therapeutics? Karyopharm Therapeutics has a market capitalization of $544.55 million and generates $1.61 million in revenue each year. The company earns $-128,980,000.00 in net income (profit) each year or ($2.81) on an earnings per share basis. Karyopharm Therapeutics employs 154 workers across the globe. What is Karyopharm Therapeutics' official website? The official website for Karyopharm Therapeutics is http://www.karyopharm.com. How can I contact Karyopharm Therapeutics? Karyopharm Therapeutics' mailing address is 85 WELLS AVENUE SECOND FLOOR, NEWTON MA, 02459. The company can be reached via phone at 617-658-0600 or via email at [email protected] MarketBeat Community Rating for Karyopharm Therapeutics (NASDAQ KPTI)Community Ranking: 3.1 out of 5 ( )Outperform Votes: 360 (Vote Outperform)Underperform Votes: 218 (Vote Underperform)Total Votes: 578MarketBeat's community ratings are surveys of what our community members think about Karyopharm Therapeutics and other stocks. Vote "Outperform" if you believe KPTI will outperform the S&P 500 over the long term. Vote "Underperform" if you believe KPTI will underperform the S&P 500 over the long term. You may vote once every thirty days. This page was last updated on 2/21/2019 by MarketBeat.com StaffFeatured Article: What is the Coverage Ratio?