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Karyopharm Therapeutics (KPTI) Competitors

Karyopharm Therapeutics logo
$8.50 -0.58 (-6.39%)
Closing price 04:00 PM Eastern
Extended Trading
$8.52 +0.03 (+0.29%)
As of 06:43 PM Eastern
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KPTI vs. VOR, ESPR, LBRX, CYRX, and AURA

Should you buy Karyopharm Therapeutics stock or one of its competitors? MarketBeat compares Karyopharm Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Karyopharm Therapeutics include Vor Biopharma (VOR), Esperion Therapeutics (ESPR), LB Pharmaceuticals (LBRX), CryoPort (CYRX), and Aura Biosciences (AURA). These companies are all part of the "pharmaceutical products" industry.

How does Karyopharm Therapeutics compare to Vor Biopharma?

Karyopharm Therapeutics (NASDAQ:KPTI) and Vor Biopharma (NASDAQ:VOR) are both small-cap pharmaceutical products companies, but which is the superior business? We will compare the two businesses based on the strength of their institutional ownership, earnings, risk, profitability, analyst recommendations, dividends, media sentiment and valuation.

Vor Biopharma has lower revenue, but higher earnings than Karyopharm Therapeutics.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Karyopharm Therapeutics$146.07M1.32-$196.04M-$15.09N/A
Vor BiopharmaN/AN/AN/AN/AN/A

Vor Biopharma has a net margin of 0.00% compared to Karyopharm Therapeutics' net margin of -129.02%.

Company Net Margins Return on Equity Return on Assets
Karyopharm Therapeutics-129.02% N/A -120.29%
Vor Biopharma N/A N/A N/A

Karyopharm Therapeutics currently has a consensus target price of $17.17, indicating a potential upside of 101.96%. Vor Biopharma has a consensus target price of $42.25, indicating a potential upside of 217.91%. Given Vor Biopharma's higher probable upside, analysts clearly believe Vor Biopharma is more favorable than Karyopharm Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Karyopharm Therapeutics
1 Sell rating(s)
0 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.86
Vor Biopharma
1 Sell rating(s)
2 Hold rating(s)
6 Buy rating(s)
2 Strong Buy rating(s)
2.82

66.4% of Karyopharm Therapeutics shares are owned by institutional investors. Comparatively, 97.3% of Vor Biopharma shares are owned by institutional investors. 1.7% of Karyopharm Therapeutics shares are owned by company insiders. Comparatively, 0.3% of Vor Biopharma shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company is poised for long-term growth.

In the previous week, Karyopharm Therapeutics had 2 more articles in the media than Vor Biopharma. MarketBeat recorded 5 mentions for Karyopharm Therapeutics and 3 mentions for Vor Biopharma. Vor Biopharma's average media sentiment score of 0.24 beat Karyopharm Therapeutics' score of 0.00 indicating that Vor Biopharma is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Karyopharm Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Vor Biopharma
0 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Karyopharm Therapeutics has a beta of 0.83, indicating that its stock price is 17% less volatile than the broader market. Comparatively, Vor Biopharma has a beta of 1.71, indicating that its stock price is 71% more volatile than the broader market.

Summary

Vor Biopharma beats Karyopharm Therapeutics on 8 of the 12 factors compared between the two stocks.

How does Karyopharm Therapeutics compare to Esperion Therapeutics?

Karyopharm Therapeutics (NASDAQ:KPTI) and Esperion Therapeutics (NASDAQ:ESPR) are both small-cap medical companies, but which is the superior business? We will contrast the two companies based on the strength of their dividends, institutional ownership, valuation, profitability, analyst recommendations, earnings, media sentiment and risk.

In the previous week, Karyopharm Therapeutics had 5 more articles in the media than Esperion Therapeutics. MarketBeat recorded 5 mentions for Karyopharm Therapeutics and 0 mentions for Esperion Therapeutics. Karyopharm Therapeutics' average media sentiment score of 0.00 equaled Esperion Therapeutics'average media sentiment score.

Company Overall Sentiment
Karyopharm Therapeutics Neutral
Esperion Therapeutics Neutral

Esperion Therapeutics has a net margin of 0.12% compared to Karyopharm Therapeutics' net margin of -129.02%. Karyopharm Therapeutics' return on equity of 0.00% beat Esperion Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Karyopharm Therapeutics-129.02% N/A -120.29%
Esperion Therapeutics 0.12%-0.14%0.12%

Esperion Therapeutics has higher revenue and earnings than Karyopharm Therapeutics. Esperion Therapeutics is trading at a lower price-to-earnings ratio than Karyopharm Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Karyopharm Therapeutics$146.07M1.32-$196.04M-$15.09N/A
Esperion Therapeutics$403.14M2.01-$22.68M-$0.06N/A

Karyopharm Therapeutics has a beta of 0.83, meaning that its share price is 17% less volatile than the broader market. Comparatively, Esperion Therapeutics has a beta of 1.07, meaning that its share price is 7% more volatile than the broader market.

Karyopharm Therapeutics presently has a consensus target price of $17.17, suggesting a potential upside of 101.96%. Esperion Therapeutics has a consensus target price of $5.54, suggesting a potential upside of 75.87%. Given Karyopharm Therapeutics' stronger consensus rating and higher probable upside, equities research analysts clearly believe Karyopharm Therapeutics is more favorable than Esperion Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Karyopharm Therapeutics
1 Sell rating(s)
0 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.86
Esperion Therapeutics
1 Sell rating(s)
6 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

66.4% of Karyopharm Therapeutics shares are held by institutional investors. Comparatively, 47.4% of Esperion Therapeutics shares are held by institutional investors. 1.7% of Karyopharm Therapeutics shares are held by insiders. Comparatively, 1.6% of Esperion Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Summary

Karyopharm Therapeutics beats Esperion Therapeutics on 9 of the 16 factors compared between the two stocks.

How does Karyopharm Therapeutics compare to LB Pharmaceuticals?

LB Pharmaceuticals (NASDAQ:LBRX) and Karyopharm Therapeutics (NASDAQ:KPTI) are both small-cap pharmaceutical products companies, but which is the better business? We will contrast the two companies based on the strength of their institutional ownership, profitability, valuation, analyst recommendations, dividends, earnings, media sentiment and risk.

In the previous week, Karyopharm Therapeutics had 5 more articles in the media than LB Pharmaceuticals. MarketBeat recorded 5 mentions for Karyopharm Therapeutics and 0 mentions for LB Pharmaceuticals. LB Pharmaceuticals' average media sentiment score of 0.00 equaled Karyopharm Therapeutics'average media sentiment score.

Company Overall Sentiment
LB Pharmaceuticals Neutral
Karyopharm Therapeutics Neutral

LB Pharmaceuticals has a net margin of 0.00% compared to Karyopharm Therapeutics' net margin of -129.02%.

Company Net Margins Return on Equity Return on Assets
LB PharmaceuticalsN/A N/A N/A
Karyopharm Therapeutics -129.02%N/A -120.29%

66.4% of Karyopharm Therapeutics shares are owned by institutional investors. 5.8% of LB Pharmaceuticals shares are owned by company insiders. Comparatively, 1.7% of Karyopharm Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

LB Pharmaceuticals currently has a consensus target price of $38.40, indicating a potential upside of 30.61%. Karyopharm Therapeutics has a consensus target price of $17.17, indicating a potential upside of 101.96%. Given Karyopharm Therapeutics' stronger consensus rating and higher possible upside, analysts clearly believe Karyopharm Therapeutics is more favorable than LB Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
LB Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.75
Karyopharm Therapeutics
1 Sell rating(s)
0 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.86

LB Pharmaceuticals has higher earnings, but lower revenue than Karyopharm Therapeutics. LB Pharmaceuticals is trading at a lower price-to-earnings ratio than Karyopharm Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
LB PharmaceuticalsN/AN/A-$25.20M-$1.73N/A
Karyopharm Therapeutics$146.07M1.32-$196.04M-$15.09N/A

Summary

LB Pharmaceuticals and Karyopharm Therapeutics tied by winning 5 of the 10 factors compared between the two stocks.

How does Karyopharm Therapeutics compare to CryoPort?

CryoPort (NASDAQ:CYRX) and Karyopharm Therapeutics (NASDAQ:KPTI) are both small-cap pharmaceutical products companies, but which is the superior stock? We will contrast the two companies based on the strength of their analyst recommendations, media sentiment, profitability, earnings, institutional ownership, risk, dividends and valuation.

CryoPort has a beta of 1.9, suggesting that its stock price is 90% more volatile than the broader market. Comparatively, Karyopharm Therapeutics has a beta of 0.83, suggesting that its stock price is 17% less volatile than the broader market.

92.9% of CryoPort shares are held by institutional investors. Comparatively, 66.4% of Karyopharm Therapeutics shares are held by institutional investors. 10.1% of CryoPort shares are held by company insiders. Comparatively, 1.7% of Karyopharm Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

CryoPort currently has a consensus price target of $15.11, indicating a potential downside of 2.38%. Karyopharm Therapeutics has a consensus price target of $17.17, indicating a potential upside of 101.96%. Given Karyopharm Therapeutics' stronger consensus rating and higher probable upside, analysts clearly believe Karyopharm Therapeutics is more favorable than CryoPort.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
CryoPort
0 Sell rating(s)
2 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.80
Karyopharm Therapeutics
1 Sell rating(s)
0 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.86

In the previous week, Karyopharm Therapeutics had 3 more articles in the media than CryoPort. MarketBeat recorded 5 mentions for Karyopharm Therapeutics and 2 mentions for CryoPort. CryoPort's average media sentiment score of 0.34 beat Karyopharm Therapeutics' score of 0.00 indicating that CryoPort is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
CryoPort
0 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Karyopharm Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

CryoPort has higher revenue and earnings than Karyopharm Therapeutics. Karyopharm Therapeutics is trading at a lower price-to-earnings ratio than CryoPort, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
CryoPort$176.18M4.43$78.30M$1.3511.47
Karyopharm Therapeutics$146.07M1.32-$196.04M-$15.09N/A

CryoPort has a net margin of 41.57% compared to Karyopharm Therapeutics' net margin of -129.02%. Karyopharm Therapeutics' return on equity of 0.00% beat CryoPort's return on equity.

Company Net Margins Return on Equity Return on Assets
CryoPort41.57% -7.92% -4.79%
Karyopharm Therapeutics -129.02%N/A -120.29%

Summary

CryoPort beats Karyopharm Therapeutics on 12 of the 17 factors compared between the two stocks.

How does Karyopharm Therapeutics compare to Aura Biosciences?

Karyopharm Therapeutics (NASDAQ:KPTI) and Aura Biosciences (NASDAQ:AURA) are both small-cap medical companies, but which is the superior business? We will compare the two businesses based on the strength of their profitability, institutional ownership, earnings, valuation, media sentiment, dividends, analyst recommendations and risk.

Aura Biosciences has lower revenue, but higher earnings than Karyopharm Therapeutics. Aura Biosciences is trading at a lower price-to-earnings ratio than Karyopharm Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Karyopharm Therapeutics$146.07M1.32-$196.04M-$15.09N/A
Aura BiosciencesN/AN/A-$106.19M-$1.74N/A

Karyopharm Therapeutics currently has a consensus target price of $17.17, indicating a potential upside of 101.96%. Aura Biosciences has a consensus target price of $20.50, indicating a potential upside of 216.36%. Given Aura Biosciences' higher probable upside, analysts clearly believe Aura Biosciences is more favorable than Karyopharm Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Karyopharm Therapeutics
1 Sell rating(s)
0 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.86
Aura Biosciences
1 Sell rating(s)
1 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.25

Aura Biosciences has a net margin of 0.00% compared to Karyopharm Therapeutics' net margin of -129.02%. Karyopharm Therapeutics' return on equity of 0.00% beat Aura Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Karyopharm Therapeutics-129.02% N/A -120.29%
Aura Biosciences N/A -78.12%-64.08%

66.4% of Karyopharm Therapeutics shares are held by institutional investors. Comparatively, 96.8% of Aura Biosciences shares are held by institutional investors. 1.7% of Karyopharm Therapeutics shares are held by company insiders. Comparatively, 6.3% of Aura Biosciences shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

Karyopharm Therapeutics has a beta of 0.83, suggesting that its share price is 17% less volatile than the broader market. Comparatively, Aura Biosciences has a beta of 0.39, suggesting that its share price is 61% less volatile than the broader market.

In the previous week, Karyopharm Therapeutics had 5 more articles in the media than Aura Biosciences. MarketBeat recorded 5 mentions for Karyopharm Therapeutics and 0 mentions for Aura Biosciences. Karyopharm Therapeutics' average media sentiment score of 0.00 equaled Aura Biosciences'average media sentiment score.

Company Overall Sentiment
Karyopharm Therapeutics Neutral
Aura Biosciences Neutral

Summary

Karyopharm Therapeutics and Aura Biosciences tied by winning 7 of the 14 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding KPTI and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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KPTI vs. The Competition

MetricKaryopharm TherapeuticsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$205.78M$2.94B$6.43B$12.05B
Dividend YieldN/A1.69%2.67%5.56%
P/E Ratio-0.5617.6823.7523.75
Price / Sales1.32296.71479.9983.74
Price / CashN/A56.1726.9937.25
Price / Book-0.533.8310.286.78
Net Income-$196.04M$75.85M$3.57B$337.51M
7 Day Performance-13.44%-4.52%-1.43%-2.72%
1 Month Performance-1.62%-5.85%3.27%1.87%
1 Year Performance89.31%15.31%23.37%26.61%

Karyopharm Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
KPTI
Karyopharm Therapeutics
2.1958 of 5 stars
$8.50
-6.4%
$17.17
+102.0%
+102.2%$205.78M$146.07MN/A380
VOR
Vor Biopharma
2.9824 of 5 stars
$14.57
-2.7%
$42.25
+190.0%
N/A$811.16MN/AN/A140
ESPR
Esperion Therapeutics
3.5491 of 5 stars
$3.13
flat
$5.54
+77.0%
+156.6%$805.76M$403.14MN/A200
LBRX
LB Pharmaceuticals
1.7844 of 5 stars
$28.03
+0.2%
$38.40
+37.0%
N/A$802.09MN/AN/A16
CYRX
CryoPort
3.392 of 5 stars
$15.99
+1.9%
$14.69
-8.1%
+124.3%$790.81M$182.94M11.841,186

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This page (NASDAQ:KPTI) was last updated on 6/8/2026 by MarketBeat.com Staff.
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