Lyra Therapeutics (LYRA) Short Interest Ratio & Short Volume $6.83 +0.25 (+3.80%) Closing price 08/4/2025 04:00 PM EasternExtended Trading$60.00 +53.17 (+778.48%) As of 04:00 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Short Interest Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock Lyra Therapeutics Short Interest DataLyra Therapeutics (LYRA) has a short interest of 49,900 shares. This marks a -59.73% decrease in short interest from the previous month. The short interest ratio (days to cover) is 0.1, indicating that it would take 0.1 days of the average trading volume of 37,837 shares to cover all short positions.Current Short Interest49,900 sharesPrevious Short Interest123,900 sharesChange Vs. Previous Month-59.73%Dollar Volume Sold Short$423.15 thousandShort Interest Ratio0.1 Days to CoverLast Record DateJuly 15, 2025Outstanding Shares1,600,000 sharesPercentage of Shares Shorted3.12%Today's Trading Volume19,183 sharesAverage Trading Volume37,837 sharesToday's Volume Vs. Average51% Short Selling Lyra Therapeutics? Sign up to receive the latest short interest report for Lyra Therapeutics and its competitors with MarketBeat's FREE newsletter. Email Address Skip Charts & View Short Interest HistoryShort Interest ChartDays to Cover ChartShort Percent of Float ChartLYRA Short Interest Over TimeLYRA Days to Cover Over TimeLYRA Percentage of Float Shorted Over Time Lyra Therapeutics Short Interest History Export to ExcelReport DateTotal Shares Sold ShortDollar Volume Sold ShortChange from Previous ReportPercentage of Float ShortedDays to CoverPrice on Report Date 7/15/202549,900 shares $423.15 thousand -59.7%N/A0.1 $8.48 6/30/2025123,900 shares $1.11 million +8.9%7.7%0.2 $8.96 6/15/2025113,800 shares $1.29 million +37.9%8.6%0.2 $11.34 5/31/202582,500 shares $386.10 thousand -43.7%7.4%0.1 $4.68 5/15/2025146,600 shares $16.54 thousand -94.6%13.1%2.3 $0.11 4/30/20252,700,000 shares $320.76 thousand +21.6%N/A1.5 $0.12 4/15/20252,220,000 shares $204.68 thousand -7.9%3.6%1.9 $0.09 3/31/20252,410,000 shares $304.38 thousand +0.4%3.9%2.2 $0.13 3/15/20252,400,000 shares $412.80 thousand +27.7%3.8%2 $0.17 2/28/20251,880,000 shares $402.32 thousand -13.4%3.0%1.5 $0.21 Get the Latest News and Ratings for LYRA and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Lyra Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 2/15/20252,170,000 shares $451.79 thousand +1.4%3.5%1.5 $0.21 1/31/20252,140,000 shares $391.19 thousand +0.5%N/A1.2 $0.18 1/15/20252,130,000 shares $402.57 thousand +1.4%N/A1.1 $0.19 12/31/20242,100,000 shares $433.44 thousand +14.1%N/A1.1 $0.21 12/15/20241,840,000 shares $335.98 thousand -16.4%N/A1.1 $0.18 11/30/20242,200,000 shares $455.40 thousand -7.6%N/A1.4 $0.21 11/15/20242,380,000 shares $404.60 thousand +16.7%N/A1.6 $0.17 10/31/20242,040,000 shares $560.80 thousand -4.7%N/A2.1 $0.27 10/15/20242,140,000 shares $488.78 thousand -24.9%N/A2.2 $0.23 9/30/20242,850,000 shares $732.45 thousand -9.2%N/A3.2 $0.26 9/15/20243,140,000 shares $879.20 thousand +6.1%N/A2.7 $0.28 8/31/20242,960,000 shares $952.23 thousand -28.7%N/A2.3 $0.32 8/15/20244,150,000 shares $1.20 million +18.6%N/A2.7 $0.29 7/31/20243,500,000 shares $1.14 million -5.9%N/A1.7 $0.33 7/15/20243,720,000 shares $1.13 million +86.9%N/A1 $0.31 6/30/20241,990,000 shares $550.63 thousand +28.4%N/A0.5 $0.28 6/15/20241,550,000 shares $457.56 thousand +71.8%N/A0.4 $0.30 5/31/2024902,200 shares $295.92 thousand +49.6%N/A0.3 $0.33 5/15/2024603,000 shares $214.55 thousand +45.7%N/A0.2 $0.36 4/30/2024413,800 shares $2.14 million +24.0%N/A0.2 $5.16 4/15/2024333,600 shares $1.76 million +49.6%N/A1 $5.27 3/31/2024223,000 shares $1.39 million +8.1%N/A0.7 $6.22 3/15/2024206,300 shares $1.22 million +28.8%N/A0.8 $5.93 2/29/2024160,200 shares $842.65 thousand -13.6%N/A0.6 $5.26 2/15/2024185,400 shares $927 thousand +43.5%N/A0.8 $5.00 1/31/2024129,200 shares $587.86 thousand -5.6%N/A0.6 $4.55 1/15/2024136,900 shares $736.52 thousand -22.6%N/A0.6 $5.38 12/31/2023176,800 shares $926.43 thousand +2.4%N/A0.9 $5.24 12/15/2023172,600 shares $802.59 thousand -24.4%N/A0.7 $4.65 11/30/2023228,300 shares $755.67 thousand -13.9%N/A0.6 $3.31Alex’s “Next Magnificent Seven” stocks (Ad)The original “Magnificent Seven” turned $7K into $1.18 million. Now, Alex Green has identified AI’s Next Magnificent Seven—seven stocks he believes could deliver similar gains in under six years. His full breakdown is now live.Watch the “Next Magnificent Seven” presentation here 11/15/2023265,200 shares $766.43 thousand -17.3%N/A0.7 $2.89 10/31/2023320,600 shares $952.18 thousand +43.2%N/A0.9 $2.97 10/15/2023223,900 shares $801.56 thousand -38.2%N/A0.6 $3.58 9/30/2023362,100 shares $1.42 million -14.0%N/A0.9 $3.91 9/15/2023421,100 shares $1.83 million +661.5%N/A1.2 $4.35 8/31/202355,300 shares $192.44 thousand -19.5%N/A0.3 $3.48 8/15/202368,700 shares $245.95 thousand -67.0%N/A0.4 $3.58 7/31/2023208,100 shares $670.08 thousand -62.3%N/A1.1 $3.22 7/15/2023552,200 shares $1.69 million -0.1%N/A3.4 $3.06 6/30/2023552,600 shares $2.27 million +23.4%N/A4.2 $4.11 6/15/2023447,700 shares $1.34 million +56.8%N/A3.9 $2.99 5/31/2023285,500 shares $733.74 thousand +1,513.0%N/A3.7 $2.57 5/15/202317,700 shares $46.20 thousand -31.4%N/A0.5 $2.61 4/30/202325,800 shares $61.92 thousand +27.1%N/A0.7 $2.40 4/15/202320,300 shares $48.52 thousand +178.1%N/A0.6 $2.39 3/31/20237,300 shares $14.67 thousand -29.1%N/A0.2 $2.01 3/15/202310,300 shares $21.01 thousand -32.2%N/A0.3 $2.04 2/28/202315,200 shares $36.18 thousand +22.6%N/A0.5 $2.38 2/15/202312,400 shares $30.26 thousand +21.6%N/A0.4 $2.44 1/31/202310,200 shares $29.07 thousand -21.5%N/A0.3 $2.85 1/15/202313,000 shares $36.01 thousand -29.7%N/A0.2 $2.77 12/30/202218,500 shares $58.09 thousand +44.5%N/A0.3 $3.14 12/15/202212,800 shares $34.94 thousand -41.6%N/A0.2 $2.73 11/30/202221,900 shares $76.87 thousand +0.5%N/A0.3 $3.51 11/15/202221,800 shares $85.02 thousand No ChangeN/A0.3 $3.90 10/31/202221,800 shares $102.24 thousand -27.6%N/A0.3 $4.69 10/15/202230,100 shares $144.48 thousand -16.4%N/A0.9 $4.80 9/30/202236,000 shares $180.36 thousand -45.4%N/A1 $5.01 9/15/202265,900 shares $392.76 thousand -25.5%N/A1.6 $5.96 8/31/202288,400 shares $511.84 thousand -18.8%N/A1.4 $5.79 8/15/2022108,800 shares $683.26 thousand -22.6%N/A1.6 $6.28 7/31/2022140,600 shares $912.49 thousand -44.2%N/A1.9 $6.49 7/15/2022252,000 shares $1.43 million -17.5%N/A2.7 $5.69 6/30/2022305,300 shares $1.72 million +13.6%N/A1.2 $5.65 6/15/2022268,700 shares $1.35 million -38.5%N/A1 $5.02 5/31/2022437,000 shares $2.34 million +5.1%N/A1.9 $5.35 5/15/2022415,800 shares $2.03 million +10.7%N/A1.8 $4.88 4/30/2022375,600 shares $2.12 million +50.0%N/A1.7 $5.65 4/15/2022250,400 shares $1.88 million +224.4%3.9%1.2 $7.51 3/31/202277,200 shares $310.34 thousand +19.0%0.9%0.5 $4.02 3/15/202264,900 shares $262.85 thousand -44.8%0.7%1.5 $4.05 2/28/2022117,500 shares $572.23 thousand +36.3%1.2%2.4 $4.87 2/15/202286,200 shares $387.90 thousand +9.1%0.9%1.6 $4.50 1/31/202279,000 shares $323.11 thousand +5.6%0.8%1.3 $4.09 1/15/202274,800 shares $295.46 thousand +4.0%0.8%1.2 $3.95 12/31/202171,900 shares $313.48 thousand -5.8%0.8%1.2 $4.36 12/15/202176,300 shares $334.19 thousand -1.0%0.8%1.4 $4.38 11/30/202177,100 shares $431.76 thousand +2.5%0.8%1.4 $5.60 11/15/202175,200 shares $539.94 thousand -51.4%0.9%1.5 $7.18 10/29/2021154,600 shares $1.13 million -3.6%1.8%3.3 $7.30Alex’s “Next Magnificent Seven” stocks (Ad)The original “Magnificent Seven” turned $7K into $1.18 million. Now, Alex Green has identified AI’s Next Magnificent Seven—seven stocks he believes could deliver similar gains in under six years. His full breakdown is now live.Watch the “Next Magnificent Seven” presentation here 10/15/2021160,400 shares $1.26 million -20.9%1.9%3.4 $7.85 9/30/2021202,700 shares $1.85 million -0.3%2.3%4.2 $9.12 9/15/2021203,300 shares $1.68 million -3.1%2.4%2.9 $8.28 8/31/2021209,700 shares $1.50 million -11.0%2.4%2.5 $7.14 8/13/2021235,700 shares $1.64 million +1.3%2.7%2.1 $6.94 7/30/2021232,700 shares $1.50 million -2.8%2.7%1.9 $6.44 7/15/2021239,400 shares $1.78 million +0.3%2.8%1.9 $7.45 6/30/2021238,700 shares $1.92 million -43.6%2.8%1.8 $8.03 6/15/2021423,100 shares $3.88 million +17.9%4.9%3.6 $9.17 5/28/2021358,900 shares $2.58 million -13.2%4.1%3.4 $7.18 5/14/2021413,600 shares $3.09 million +14.1%4.8%4.6 $7.46 4/30/2021362,500 shares $3.69 million +10.9%4.4%2.4 $10.18 4/15/2021327,000 shares $3.56 million +4.1%3.9%2.1 $10.89 3/31/2021314,200 shares $3.51 million +11.3%3.8%2.1 $11.17 3/15/2021282,300 shares $3.95 million +15.4%3.4%1.8 $13.98 2/26/2021244,600 shares $3.42 million +73.6%3.1%1.3 $14.00 2/12/2021140,900 shares $1.86 million -1.4%1.8%0.7 $13.19 1/29/2021142,900 shares $1.53 million +9.3%1.8%1.1 $10.68 1/15/2021130,800 shares $1.43 million No Change1.6%1.1 $10.96 LYRA Short Interest - Frequently Asked Questions What is Lyra Therapeutics' current short interest? Short interest is the volume of Lyra Therapeutics shares that have been sold short but have not yet been closed out or covered. As of July 15th, traders have sold 49,900 shares of LYRA short. Learn More on Lyra Therapeutics' current short interest. Is Lyra Therapeutics' short interest increasing or decreasing? Lyra Therapeutics saw a decrease in short interest in July. As of July 15th, there was short interest totaling 49,900 shares, a decrease of 59.7% from the previous total of 123,900 shares. Changes in short volume can be used to identify positive and negative investor sentiment. Investors that short sell a stock are betting that its price will decline in the future. An increase in short sale volume suggests bearish (negative) sentiment among investors. A decrease on short sale volume suggests bullish (positive) sentiment. How does Lyra Therapeutics' short interest compare to its competitors? Here is how the short interest of companies in the industry of "medical equipment" compare to Lyra Therapeutics: Modular Medical, Inc. (0.27%), Milestone Scientific Inc. (0.16%), Nephros Inc. (0.04%), PolyPid Ltd. (0.98%), Precision Optics Corp. (1.12%), Envoy Medical, Inc. (1.14%), Plus Therapeutics, Inc. (6.18%), Vivos Therapeutics, Inc. (9.73%), CollPlant Biotechnologies Ltd. Sponsored ADR (1.28%), Femasys Inc. (0.52%), Which stocks are the most shorted right now? As of the most recent reporting period, the following stocks had the largest short interest positions: Coinbase Global, Inc. ($5.11 billion), Charter Communications, Inc. ($4.76 billion), Reddit Inc. ($2.84 billion), SoFi Technologies, Inc. ($2.79 billion), Seagate Technology Holdings PLC ($2.79 billion), Live Nation Entertainment, Inc. ($2.67 billion), Rocket Lab Corporation ($2.49 billion), AST SpaceMobile, Inc. ($2.12 billion), Moderna, Inc. ($2.09 billion), and Omnicom Group Inc. ($2.04 billion). View all of the most shorted stocks. What does it mean to sell short Lyra Therapeutics stock? Short selling LYRA is an investing strategy that aims to generate trading profit from Lyra Therapeutics as its price is falling. LYRA shares are trading up $0.25 today. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit. How does a short squeeze work against Lyra Therapeutics? A short squeeze for Lyra Therapeutics occurs when it has a large amount of short interest and its stock appreciates in price. This forces short sellers to cover their short interest positions by buying actual shares of LYRA, which in turn drives the price of the stock up even further. How often is Lyra Therapeutics' short interest reported? Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including LYRA, twice per month. The most recent reporting period available is July, 15 2025. More Short Interest Resources from MarketBeat Related Companies Modular Medical Short Interest Data Milestone Scientific Short Interest Data Nephros Short Interest Data PolyPid Short Interest Data Precision Optics Short Interest Data Envoy Medical Short Interest Data Plus Therapeutics Short Interest Data Vivos Therapeutics Short Interest Data CollPlant Biotechnologies Short Interest Data Femasys Short Interest Data Short Interest Tools Stocks to Short Largest Short Interest Positions Short Interest Increases Short Interest Decreases Short Interest Reporting Dates This page (NASDAQ:LYRA) was last updated on 8/5/2025 by MarketBeat.com Staff From Our PartnersMan Who Called Nvidia at $1.10 Says Buy This Now...In 2004, one man called Nvidia before just about anyone knew it existed. 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