Positive News SentimentPositive NewsNASDAQ:MCRB Seres Therapeutics (MCRB) Stock Price, News & Analysis $4.00 -0.10 (-2.44%) Closing price 09/18/2026 04:00 PM EasternExtended Trading$3.98 -0.02 (-0.38%) As of 09/18/2026 07:30 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsInsider TradesNews and TrendsOptions ChainOwnershipSEC Filings About Seres Therapeutics Stock (NASDAQ:MCRB) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Seres Therapeutics alerts:Sign Up Key Stats Today's Range$4.00▼$4.2750-Day Range$4.00▼$5.7252-Week Range$4.00▼$29.98Volume95,087 shsAverage Volume52,006 shsMarket Capitalization$40.20 millionP/E RatioN/ADividend YieldN/APrice Target$17.00Consensus RatingHold Company Overview Seres Therapeutics, Inc. is a biotechnology company focused on developing live biotherapeutics designed to treat diseases by restoring or modifying the human microbiome. The company’s research has centered on microbial communities that may influence immune function, gastrointestinal health and disease progression. Seres’ lead product, VOWST (fecal microbiota spores, live-brpk), was developed to reduce the recurrence of Clostridioides difficile infection in adults following antibacterial treatment. The orally administered therapy uses purified bacterial spores to help restore the gut microbiome and received approval from the U.S. Food and Drug Administration in 2023. Founded in 2010 and headquartered in Cambridge, Massachusetts, Seres has pursued microbiome-based therapies for gastrointestinal and immune-mediated conditions. The company’s programs have included treatments intended to support patients undergoing hematopoietic stem cell transplantation and other therapies that can disrupt the intestinal microbiome. Seres has served primarily the U.S. market through its development and commercialization activities and has worked with pharmaceutical and healthcare partners to advance its products.AI Generated. May Contain Errors. Read More Seres Therapeutics Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks71st Percentile Overall ScoreMCRB MarketRank™: Seres Therapeutics scored higher than 71% of companies evaluated by MarketBeat, and ranked 195th out of 897 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion3.7 / 5Analyst RatingHold Consensus RatingSeres Therapeutics has received a consensus rating of Hold. The company's average rating score is 2.25, and is based on no strong buy ratings, 2 buy ratings, 1 hold rating, and 1 sell rating.Upside PotentialSeres Therapeutics has a consensus price target of $17.00, representing about 325.0% upside from its current price of $4.00.Amount of Analyst CoverageSeres Therapeutics has only been the subject of 3 research reports in the past 90 days.Read more about Seres Therapeutics' stock forecast and price target. Earnings and Valuation1.3 / 5Proj. Earnings GrowthGrowing Earnings GrowthEarnings for Seres Therapeutics are expected to grow in the coming year, from ($6.33) to ($2.06) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Seres Therapeutics is -1.65, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Seres Therapeutics is -1.65, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioSeres Therapeutics has a P/B Ratio of 0.82. P/B Ratios below 1 indicate that a company could be undervalued with respect to its assets and liabilities.Read more about Seres Therapeutics' valuation and earnings. Short Interest3.0 / 5Short Interest LevelHealthy Percentage of Shares Shorted3.74% of the float of Seres Therapeutics has been sold short.Short Interest Ratio / Days to CoverSeres Therapeutics has a short interest ratio ("days to cover") of 6.11.Change versus previous monthShort interest in Seres Therapeutics has recently decreased by 3.08%, indicating that investor sentiment is improving. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldSeres Therapeutics does not currently pay a dividend.Dividend GrowthSeres Therapeutics does not have a long track record of dividend growth. News and Social Media3.0 / 5News SentimentN/A News SentimentSeres Therapeutics has a news sentiment score of 1.87. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a higher news sentiment than the 0.56 average news sentiment score of Healthcare companies.Search InterestOnly 1 people have searched for MCRB on MarketBeat in the last 30 days. This is a decrease of -50% compared to the previous 30 days. Company Ownership1.6 / 5Insider TradingSelling Shares Insider Buying vs. Insider SellingIn the past three months, Seres Therapeutics insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $2,230.00 in company stock.Percentage Held by Insiders5.20% of the stock of Seres Therapeutics is held by insiders.Percentage Held by Institutions59.34% of the stock of Seres Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Seres Therapeutics' insider trading history. 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Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. MCRB Stock News HeadlinesSeres Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)September 8, 2026 | globenewswire.comSeres Therapeutics to Participate in H.C. Wainwright 28th Annual Global Investment ConferenceSeptember 1, 2026 | globenewswire.comThe hidden costs of a hands-off retirement accountContributing to your 401(k) consistently is good financial behavior - but contributing and optimizing are two different things. High fees, heavy company stock concentration, and target-date funds that follow a formula rather than your situation can quietly erode your balance over time. 74% of U.S. millionaires work with a financial advisor - more than double the general population rate. A fiduciary advisor can review your 401(k) for fees, allocation, and alignment with your actual timeline. SmartAsset's free quiz matches nearly 50,000 people each month with vetted fiduciary advisors in their area.September 20 at 1:00 AM | SmartAsset (Ad)Canaccord Genuity Reaffirms Their Buy Rating on Seres Therapeutics (MCRB)August 20, 2026 | theglobeandmail.comSeres Therapeutics: Q2 Earnings SnapshotAugust 5, 2026 | finance.yahoo.comSeres Therapeutics Reports Second Quarter 2026 Financial Results and Provides Business Updates, Including Further Action to Reduce Ongoing Facilities CostsAugust 5, 2026 | finance.yahoo.comSeres Therapeutics Streamlines Cambridge Operations with Lease ChangesAugust 4, 2026 | tipranks.comSeres Therapeutics' SER-155 posts 80% response in cancer immunotherapy GI toxicity studyJuly 11, 2026 | msn.comSee More Headlines MCRB Stock Analysis - Frequently Asked Questions How have MCRB shares performed this year? Seres Therapeutics' stock was trading at $14.88 on January 1st, 2026. Since then, MCRB shares have decreased by 73.1% and is now trading at $4.00. How were Seres Therapeutics' earnings last quarter? Seres Therapeutics, Inc. (NASDAQ:MCRB) posted its earnings results on Wednesday, August, 5th. The biotechnology company reported $0.47 earnings per share for the quarter, beating analysts' consensus estimates of ($2.18) by $2.65. The biotechnology company had revenue of $0.74 million for the quarter, compared to the consensus estimate of $0.18 million. Seres Therapeutics had a negative net margin of 1,192.94% and a negative trailing twelve-month return on equity of 114.82%. When did Seres Therapeutics' stock split? Shares of Seres Therapeutics reverse split before market open on Tuesday, April 22nd 2025.The 1-20 reverse split was announced on Thursday, April 10th 2025. The number of shares owned by shareholders was adjusted after the closing bell on Monday, April 21st 2025. An investor that had 100 shares of stock prior to the reverse split would have 5 shares after the split. When did Seres Therapeutics IPO? Seres Therapeutics (MCRB) raised $119 million in an IPO on Friday, June 26th 2015. The company issued 7,430,555 shares at a price of $15.00-$17.00 per share. Goldman Sachs and BofA Merrill Lynch served as the underwriters for the IPO and Leerink Partners and Canaccord Genuity were co-managers. Who are Seres Therapeutics' major shareholders? Top institutional investors of Seres Therapeutics include Integrated Wealth Concepts LLC (0.04%). Insiders that own company stock include Eric D Shaff, Kelly Brady, Thomas Desrosier, Matthew R Henn, Teresa L Young, Paula Cloghessy and Moltke Lisa Von. View institutional ownership trends. How do I buy shares of Seres Therapeutics? Shares of MCRB stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Seres Therapeutics own? Based on aggregate information from My MarketBeat watchlists, some other companies that Seres Therapeutics investors own include PayPal (PYPL), NVIDIA (NVDA), Meta Platforms (META), Tesla (TSLA), Micron Technology (MU), Qualcomm (QCOM) and NIO (NIO). Company Calendar Last Earnings8/05/2026Today9/20/2026Next Earnings (Estimated)11/04/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Red Zone (3m+) 1-Year History Sep 25 Dec 25 Mar 26 Jun 26 Sep 26 MCRB's financial health is in the Red zone, according to TradeSmith. MCRB has been in this zone for over 3 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorHealthcare Industry Biotechnology Sub-IndustryBiotechnology Current SymbolNASDAQ:MCRB CIK1609809 Webwww.serestherapeutics.com Phone(617) 945-9626FaxN/AEmployees66Year Founded2010Price Target and Rating Average Price Target for Seres Therapeutics$17.00 High Price Target$22.00 Low Price Target$12.00 Potential Upside/Downside+325.0%Consensus RatingHold Rating Score (0-4)2.25 Research Coverage4 Analysts Profitability EPS (Trailing Twelve Months)($2.43) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income$5.70 million Net Margins-1,192.94% Pretax Margin-1,192.94% Return on Equity-114.82% Return on Assets-34.15% Debt Debt-to-Equity RatioN/A Current Ratio2.11 Quick Ratio2.11 Sales & Book Value Annual Sales$790 thousand Price / Sales50.89 Cash Flow$1.09 per share Price / Cash Flow3.68 Book Value$4.89 per share Price / Book0.82Miscellaneous Outstanding Shares10,050,000Free Float9,523,000Market Cap$40.20 million OptionableOptionable Beta0.21 Social Links The 7 Hottest IPO Stories of 2026MarketBeat just released its list of the 7 hottest IPOs expected to hit Wall Street in 2026. See which companies are preparing to go public and why investors are watching closely.Get This Free Report This page (NASDAQ:MCRB) was last updated on 9/20/2026 by MarketBeat.com Staff. From Our Partners$40,000,000,000,000The national debt just hit 40 trillion dollars, and the U.S. now spends more on interest payments than on its ...American Alternative | Sponsored“Elon’s nightmare” could fund your retirementMarc Chaikin, the 60 year Wall Street veteran whose Chaikin Money Flow indicator sits on every Bloomberg termi...Chaikin Analytics | SponsoredYou’ve never seen anything like this beforeFor centuries, families like the Rothschilds, Morgans, and Rockefellers have quietly used one overlooked type ...Porter & Company | SponsoredBank of America: 'Digital Dollar Inevitable'Bank of America just revealed your expiration date. 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