| 5/16/2025 | Woodline Partners LP | 296,148 | $11.57M | 0.1% | +0.9% | 0.463% | |
| 5/16/2025 | Zimmer Partners LP | 24,500 | $957K | 0.0% | N/A | 0.038% | |
| 5/16/2025 | Octagon Capital Advisors LP | 296,000 | $11.57M | 1.2% | N/A | 0.462% | |
| 5/16/2025 | Caxton Associates LLP | 8,880 | $347K | 0.0% | N/A | 0.014% | |
| 5/16/2025 | Fred Alger Management LLC | 642,881 | $25.12M | 0.1% | -4.6% | 1.004% | |
| 5/16/2025 | Goldman Sachs Group Inc. | 1,292,608 | $50.50M | 0.0% | -22.8% | 2.019% | |
| 5/16/2025 | Millennium Management LLC | 344,320 | $13.45M | 0.0% | +3,343.2% | 0.538% | |
| 5/16/2025 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 13,933 | $544K | 0.0% | -9.9% | 0.022% | |
| 5/16/2025 | Granahan Investment Management LLC | 142,220 | $5.56M | 0.3% | +4.2% | 0.222% | |
| 5/16/2025 | Alliancebernstein L.P. | 966,090 | $37.75M | 0.0% | -5.5% | 1.509% | |
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| 5/16/2025 | Advisors Asset Management Inc. | 4,009 | $157K | 0.0% | +81.7% | 0.006% | |
| 5/16/2025 | ADAR1 Capital Management LLC | 5,424 | $212K | 0.0% | -68.9% | 0.008% | |
| 5/15/2025 | Vestal Point Capital LP | 200,000 | $7.81M | 0.6% | N/A | 0.312% | |
| 5/15/2025 | Birchview Capital LP | 8,000 | $313K | 0.3% | +100.0% | 0.012% | |
| 5/15/2025 | MPM Bioimpact LLC | 316,049 | $12.35M | 2.1% | +0.3% | 0.494% | |
| 5/15/2025 | Cubist Systematic Strategies LLC | 24,819 | $970K | 0.0% | N/A | 0.039% | |
| 5/15/2025 | Royal Bank of Canada | 15,554 | $608K | 0.0% | -2.1% | 0.024% | |
| 5/15/2025 | Quarry LP | 2,400 | $94K | 0.0% | N/A | 0.004% | |
| 5/15/2025 | Paradigm Biocapital Advisors LP | 627,423 | $24.51M | 1.2% | -64.6% | 0.980% | |
| 5/14/2025 | Walleye Capital LLC | 26,764 | $1.05M | 0.0% | -87.2% | 0.042% | |
| 5/14/2025 | Price T Rowe Associates Inc. MD | 2,973,830 | $116.19M | 0.0% | -11.1% | 4.646% | |
| 5/14/2025 | Candriam S.C.A. | 174,520 | $6.82M | 0.0% | -23.3% | 0.273% | |
| 5/14/2025 | Wellington Management Group LLP | 32,163 | $1.26M | 0.0% | -67.5% | 0.050% | |
| 5/13/2025 | Russell Investments Group Ltd. | 5,460 | $213K | 0.0% | -90.2% | 0.009% | |
| 5/12/2025 | Nuveen LLC | 673,343 | $26.31M | 0.0% | N/A | 1.052% | |
| 5/9/2025 | Westfield Capital Management Co. LP | 1,434,770 | $56.06M | 0.3% | +9.4% | 2.241% | |
| 5/9/2025 | BIT Capital GmbH | 14,610 | $571K | 0.0% | -29.6% | 0.023% | |
| 5/9/2025 | PNC Financial Services Group Inc. | 9,200 | $359K | 0.0% | +8.2% | 0.014% | |
| 5/8/2025 | Jefferies Financial Group Inc. | 10,000 | $391K | 0.0% | +60.0% | 0.016% | |
| 5/8/2025 | US Bancorp DE | 2,208 | $86K | 0.0% | +114.4% | 0.003% | |
| 5/8/2025 | XTX Topco Ltd | 8,495 | $332K | 0.0% | N/A | 0.013% | |
| 5/8/2025 | Federated Hermes Inc. | 1,269,351 | $49.59M | 0.1% | -0.8% | 1.983% | |
| 5/7/2025 | TD Asset Management Inc | 216,904 | $8.47M | 0.0% | -17.1% | 0.339% | |
| 5/6/2025 | Legato Capital Management LLC | 6,142 | $240K | 0.0% | N/A | 0.010% | |
| 5/6/2025 | Universal Beteiligungs und Servicegesellschaft mbH | 14,790 | $578K | 0.0% | -26.6% | 0.023% | |
| 5/2/2025 | Victory Capital Management Inc. | 258,150 | $10.09M | 0.0% | +44.6% | 0.403% | |
| 5/1/2025 | Rice Hall James & Associates LLC | 137,516 | $5.37M | 0.3% | +23.7% | 0.215% | |
| 5/1/2025 | New York State Common Retirement Fund | 6,992 | $273K | 0.0% | N/A | 0.011% | |
| 4/30/2025 | Alps Advisors Inc. | 47,101 | $1.84M | 0.0% | -7.6% | 0.074% | |
| 4/29/2025 | Envestnet Asset Management Inc. | 14,225 | $556K | 0.0% | +58.6% | 0.022% | |
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| 4/29/2025 | Moody Aldrich Partners LLC | 55,245 | $2.16M | 0.5% | N/A | 0.086% | |
| 4/28/2025 | Teacher Retirement System of Texas | 5,940 | $232K | 0.0% | -9.1% | 0.009% | |
| 4/14/2025 | Harbor Capital Advisors Inc. | 102,020 | $3.99M | 0.2% | +28.1% | 0.159% | |
| 3/24/2025 | Wellington Management Group LLP | 99,098 | $5.37M | 0.0% | -48.4% | 0.155% | |
| 2/28/2025 | Universal Beteiligungs und Servicegesellschaft mbH | 20,141 | $1.09M | 0.0% | N/A | 0.032% | |
| 2/27/2025 | Jefferies Financial Group Inc. | 6,250 | $338K | 0.0% | N/A | 0.010% | |
| 2/17/2025 | UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 42,236 | $2.29M | 0.0% | +17.9% | 0.066% | |
| 2/17/2025 | Woodline Partners LP | 293,535 | $15.90M | 0.1% | +26.3% | 0.459% | |
| 2/17/2025 | Wexford Capital LP | 24,000 | $1.30M | 0.2% | +71.4% | 0.038% | |
| 2/17/2025 | Point72 Asset Management L.P. | 98,719 | $5.35M | 0.0% | N/A | 0.154% | |
| 2/17/2025 | Polar Capital Holdings Plc | 1,100,000 | $59.57M | 0.3% | +120.0% | 1.721% | |
| 2/17/2025 | MPM Bioimpact LLC | 315,230 | $17.07M | 2.4% | -9.7% | 0.493% | |
| 2/17/2025 | Paradigm Biocapital Advisors LP | 1,772,211 | $95.97M | 3.3% | +90.3% | 2.773% | |
| 2/17/2025 | Parkman Healthcare Partners LLC | 54,294 | $2.94M | 0.4% | -47.2% | 0.085% | |
| 2/17/2025 | Nuveen Asset Management LLC | 595,581 | $32.25M | 0.0% | +2.5% | 0.932% | |
| 2/17/2025 | OCONNOR A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS LLC | 20,740 | $1.12M | 0.1% | +29.6% | 0.032% | |
| 2/17/2025 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 15,456 | $837K | 0.0% | +13.7% | 0.024% | |
| 2/17/2025 | Integral Health Asset Management LLC | 200,000 | $10.83M | 0.9% | -9.1% | 0.313% | |
| 2/17/2025 | Jefferies Financial Group Inc. | 6,250 | $338K | 0.0% | N/A | 0.010% | |
| 2/17/2025 | Granahan Investment Management LLC | 136,438 | $7.39M | 0.3% | -21.0% | 0.214% | |
| 2/17/2025 | Ensign Peak Advisors Inc | 9,139 | $495K | 0.0% | -78.4% | 0.014% | |
| 2/17/2025 | Fred Alger Management LLC | 673,773 | $36.49M | 0.2% | +1.1% | 1.054% | |
| 2/17/2025 | Deutsche Bank AG | 903 | $49K | 0.0% | +59.8% | 0.001% | |
| 2/17/2025 | Caption Management LLC | 12,371 | $670K | 0.0% | N/A | 0.019% | |
| 2/17/2025 | BVF Inc. IL | 19,751,284 | $1.07B | 36.3% | -9.2% | 30.910% | |
| 2/17/2025 | Balyasny Asset Management L.P. | 206,568 | $11.19M | 0.0% | -42.7% | 0.323% | |
| 2/17/2025 | Bank of America Corp DE | 45,540 | $2.47M | 0.0% | -62.7% | 0.071% | |
| 2/17/2025 | BNP Paribas Financial Markets | 7,633 | $413K | 0.0% | N/A | 0.012% | |
| 2/17/2025 | Ameriprise Financial Inc. | 204,373 | $11.07M | 0.0% | +28.3% | 0.320% | |
| 2/14/2025 | Schonfeld Strategic Advisors LLC | 3,911 | $212K | 0.0% | -95.5% | 0.006% | |
| 2/14/2025 | Northern Trust Corp | 14,261 | $772K | 0.0% | +161.7% | 0.022% | |
| 2/14/2025 | The Manufacturers Life Insurance Company | 142,702 | $7.73M | 0.0% | +20.8% | 0.223% | |
| 2/14/2025 | Decheng Capital LLC | 171,600 | $9.29M | 2.0% | +3.0% | 0.269% | |
| 2/14/2025 | Birchview Capital LP | 4,000 | $217K | 0.2% | N/A | 0.006% | |
| 2/14/2025 | Virtus ETF Advisers LLC | 1,322 | $72K | 0.0% | -38.9% | 0.002% | |
| 2/14/2025 | Voya Investment Management LLC | 448,860 | $24.31M | 0.0% | +9.7% | 0.702% | |
| 2/14/2025 | Adage Capital Partners GP L.L.C. | 155,000 | $8.39M | 0.0% | -69.3% | 0.243% | |
| 2/14/2025 | Hood River Capital Management LLC | 649,590 | $35.18M | 0.5% | +0.5% | 1.017% | |
| 2/14/2025 | Price T Rowe Associates Inc. MD | 3,343,643 | $181.06M | 0.0% | +12.2% | 5.233% | |
| 2/14/2025 | Dimensional Fund Advisors LP | 64,384 | $3.49M | 0.0% | N/A | 0.101% | |
| 2/13/2025 | Marshall Wace LLP | 1,245,299 | $67.43M | 0.1% | +7.9% | 1.949% | |
| 2/13/2025 | PEAK6 LLC | 5,000 | $271K | 0.0% | N/A | 0.008% | |
| 2/13/2025 | Mariner LLC | 5,028 | $272K | 0.0% | N/A | 0.008% | |
| 2/13/2025 | Barclays PLC | 4,646 | $252K | 0.0% | -17.6% | 0.007% | |
| 2/13/2025 | Legal & General Group Plc | 19,480 | $1.06M | 0.0% | -6.6% | 0.030% | |
| 2/13/2025 | ADAR1 Capital Management LLC | 17,424 | $944K | 0.2% | -25.7% | 0.027% | |
| 2/13/2025 | FMR LLC | 6,341,391 | $343.39M | 0.0% | +28.1% | 9.924% | |
| 2/13/2025 | Federated Hermes Inc. | 1,280,052 | $69.32M | 0.2% | +13.2% | 2.003% | |
| 2/13/2025 | Finepoint Capital LP | 447,935 | $24.26M | 1.5% | +15.2% | 0.701% | |
| 2/13/2025 | Russell Investments Group Ltd. | 55,890 | $3.03M | 0.0% | -9.9% | 0.087% | |
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| 2/12/2025 | Cinctive Capital Management LP | 10,576 | $573K | 0.0% | N/A | 0.017% | |
| 2/12/2025 | Geode Capital Management LLC | 58,950 | $3.19M | 0.0% | +0.9% | 0.092% | |
| 2/12/2025 | Alliancebernstein L.P. | 1,022,604 | $55.37M | 0.0% | +2.5% | 1.600% | |
| 2/12/2025 | Wellington Management Group LLP | 99,098 | $5.37M | 0.0% | -48.4% | 0.155% | |
| 2/12/2025 | Clearbridge Investments LLC | 43,380 | $2.35M | 0.0% | +26.6% | 0.068% | |
| 2/12/2025 | DnB Asset Management AS | 8,356 | $452K | 0.0% | +11.3% | 0.013% | |
| 2/12/2025 | Pictet Asset Management Holding SA | 346,617 | $18.77M | 0.0% | -2.9% | 0.542% | |
| 2/12/2025 | BIT Capital GmbH | 20,748 | $1.12M | 0.1% | N/A | 0.032% | |
| 2/11/2025 | LPL Financial LLC | 8,146 | $441K | 0.0% | +19.5% | 0.013% | |
| 2/11/2025 | KLP Kapitalforvaltning AS | 4,500 | $244K | 0.0% | N/A | 0.007% | |
