This company has been marked as potentially delisted and may not be actively trading. Nightstar Therapeutics (NITE) Competitors Add Compare Share Share Competitors Stock AnalysisCompetitorsTrendsBuy This Stock NITE vs. KRYS, ACLX, SWTX, ALVO, CRSP, SRRK, KYMR, IMVT, IBRX, and BCRXShould you be buying Nightstar Therapeutics stock or one of its competitors? The main competitors of Nightstar Therapeutics include Krystal Biotech (KRYS), Arcellx (ACLX), SpringWorks Therapeutics (SWTX), Alvotech (ALVO), CRISPR Therapeutics (CRSP), Scholar Rock (SRRK), Kymera Therapeutics (KYMR), Immunovant (IMVT), ImmunityBio (IBRX), and BioCryst Pharmaceuticals (BCRX). These companies are all part of the "medical" sector. Nightstar Therapeutics vs. Its Competitors Krystal Biotech Arcellx SpringWorks Therapeutics Alvotech CRISPR Therapeutics Scholar Rock Kymera Therapeutics Immunovant ImmunityBio BioCryst Pharmaceuticals Nightstar Therapeutics (NASDAQ:NITE) and Krystal Biotech (NASDAQ:KRYS) are both medical companies, but which is the better stock? We will contrast the two companies based on the strength of their media sentiment, profitability, institutional ownership, valuation, earnings, dividends, community ranking, analyst recommendations and risk. Which has more risk & volatility, NITE or KRYS? Nightstar Therapeutics has a beta of 2.84, meaning that its share price is 184% more volatile than the S&P 500. Comparatively, Krystal Biotech has a beta of 0.65, meaning that its share price is 35% less volatile than the S&P 500. Do insiders & institutionals have more ownership in NITE or KRYS? 32.8% of Nightstar Therapeutics shares are held by institutional investors. Comparatively, 86.3% of Krystal Biotech shares are held by institutional investors. 13.7% of Krystal Biotech shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term. Does the media prefer NITE or KRYS? In the previous week, Krystal Biotech had 7 more articles in the media than Nightstar Therapeutics. MarketBeat recorded 7 mentions for Krystal Biotech and 0 mentions for Nightstar Therapeutics. Krystal Biotech's average media sentiment score of 1.42 beat Nightstar Therapeutics' score of 0.00 indicating that Krystal Biotech is being referred to more favorably in the news media. Company Overall Sentiment Nightstar Therapeutics Neutral Krystal Biotech Positive Does the MarketBeat Community believe in NITE or KRYS? Krystal Biotech received 74 more outperform votes than Nightstar Therapeutics when rated by MarketBeat users. However, 69.88% of users gave Nightstar Therapeutics an outperform vote while only 67.80% of users gave Krystal Biotech an outperform vote. CompanyUnderperformOutperformNightstar TherapeuticsOutperform Votes22569.88% Underperform Votes9730.12% Krystal BiotechOutperform Votes29967.80% Underperform Votes14232.20% Which has preferable earnings and valuation, NITE or KRYS? Krystal Biotech has higher revenue and earnings than Nightstar Therapeutics. Nightstar Therapeutics is trading at a lower price-to-earnings ratio than Krystal Biotech, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioNightstar TherapeuticsN/AN/A-$36.86M-$1.26-23.76Krystal Biotech$333.45M11.80$10.93M$4.1632.74 Do analysts prefer NITE or KRYS? Krystal Biotech has a consensus price target of $211.13, indicating a potential upside of 55.02%. Given Krystal Biotech's stronger consensus rating and higher possible upside, analysts plainly believe Krystal Biotech is more favorable than Nightstar Therapeutics.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Nightstar Therapeutics 0 Sell rating(s) 0 Hold rating(s) 0 Buy rating(s) 0 Strong Buy rating(s) 0.00Krystal Biotech 0 Sell rating(s) 1 Hold rating(s) 7 Buy rating(s) 1 Strong Buy rating(s) 3.00 Is NITE or KRYS more profitable? Krystal Biotech has a net margin of 30.69% compared to Nightstar Therapeutics' net margin of 0.00%. Krystal Biotech's return on equity of 11.41% beat Nightstar Therapeutics' return on equity.Company Net Margins Return on Equity Return on Assets Nightstar TherapeuticsN/A -30.89% -27.65% Krystal Biotech 30.69%11.41%10.40% SummaryKrystal Biotech beats Nightstar Therapeutics on 16 of the 18 factors compared between the two stocks. Get Nightstar Therapeutics News Delivered to You Automatically Sign up to receive the latest news and ratings for NITE and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding NITE and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart NITE vs. The Competition Export to ExcelMetricNightstar TherapeuticsBiological Products, Except Diagnostic IndustryMedical SectorNASDAQ ExchangeMarket Cap$1.00B$3.08B$5.59B$8.51BDividend YieldN/A1.56%5.28%4.17%P/E Ratio-23.7632.5027.2019.68Price / SalesN/A456.34409.08153.66Price / CashN/A168.6838.3234.64Price / Book5.083.366.974.61Net Income-$36.86M-$72.35M$3.23B$248.06M Nightstar Therapeutics Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)NITENightstar TherapeuticsN/A$29.94-1.0%N/A+19.0%$1.00BN/A-23.7647KRYSKrystal Biotech4.6481 of 5 stars$130.91+4.4%$211.13+61.3%-22.9%$3.78B$333.45M43.78210Positive NewsAnalyst RevisionACLXArcellx2.6407 of 5 stars$65.14+5.2%$111.33+70.9%+20.8%$3.59B$76.81M-91.7580Insider TradeAnalyst RevisionGap DownSWTXSpringWorks Therapeutics1.5825 of 5 stars$46.75+0.2%$52.57+12.5%+20.4%$3.52B$219.67M-13.43230Positive NewsALVOAlvotech1.737 of 5 stars$11.45+2.0%$18.00+57.2%-30.9%$3.45B$585.60M-6.194Short Interest ↑CRSPCRISPR Therapeutics3.437 of 5 stars$38.04+2.9%$71.75+88.6%-36.3%$3.29B$35M-8.70473Positive NewsAnalyst RevisionSRRKScholar Rock4.3998 of 5 stars$30.94+4.0%$42.67+37.9%+254.8%$2.94B$33.19M-13.17140KYMRKymera Therapeutics3.3144 of 5 stars$43.58+1.0%$59.35+36.2%+36.7%$2.84B$58.89M-18.62170Gap DownHigh Trading VolumeIMVTImmunovant1.5451 of 5 stars$15.44+0.2%$38.33+148.3%-37.6%$2.62BN/A-5.89120Positive NewsAnalyst RevisionIBRXImmunityBio2.3489 of 5 stars$2.71+1.5%$12.25+352.0%-43.0%$2.39B$31.22M-2.95590Gap DownBCRXBioCryst Pharmaceuticals4.4116 of 5 stars$11.19+4.3%$16.56+47.9%+65.1%$2.34B$503.49M-18.34530Positive NewsAnalyst Revision Related Companies and Tools Related Companies KRYS Alternatives ACLX Alternatives SWTX Alternatives ALVO Alternatives CRSP Alternatives SRRK Alternatives KYMR Alternatives IMVT Alternatives IBRX Alternatives BCRX Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:NITE) was last updated on 6/13/2025 by MarketBeat.com Staff From Our PartnersElon’s NEXT Big IPO?Cancel your internet TODAY!? 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