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Protalix BioTherapeutics (PLX) Competitors

Protalix BioTherapeutics logo
$2.69 -0.01 (-0.37%)
Closing price 09/18/2026 04:00 PM Eastern
Extended Trading
$2.67 -0.02 (-0.82%)
As of 09/18/2026 07:56 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

PLX vs. OLMA, CADL, GERN, RIGL, and CLYM

Should you buy Protalix BioTherapeutics stock or one of its competitors? Protalix BioTherapeutics's main competitors and comparable companies include Olema Pharmaceuticals (OLMA), Candel Therapeutics (CADL), Geron (GERN), Rigel Pharmaceuticals (RIGL), and Climb Bio (CLYM). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Protalix BioTherapeutics compare to Olema Pharmaceuticals?

Protalix BioTherapeutics (NYSE:PLX) and Olema Pharmaceuticals (NASDAQ:OLMA) are both small-cap healthcare companies, but which is the better investment? We will compare the two companies based on the strength of their earnings, media sentiment, valuation, institutional ownership, risk, profitability, analyst recommendations and dividends.

Protalix BioTherapeutics has a beta of 0.02, indicating that its share price is 98% less volatile than the broader market. Comparatively, Olema Pharmaceuticals has a beta of 1.98, indicating that its share price is 98% more volatile than the broader market.

16.5% of Protalix BioTherapeutics shares are owned by institutional investors. Comparatively, 91.8% of Olema Pharmaceuticals shares are owned by institutional investors. 6.7% of Protalix BioTherapeutics shares are owned by company insiders. Comparatively, 12.6% of Olema Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

Protalix BioTherapeutics has higher revenue and earnings than Olema Pharmaceuticals. Olema Pharmaceuticals is trading at a lower price-to-earnings ratio than Protalix BioTherapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Protalix BioTherapeutics$80.62M2.69$8.31M$0.2311.70
Olema PharmaceuticalsN/AN/A-$162.45M-$2.12N/A

In the previous week, Olema Pharmaceuticals had 2 more articles in the media than Protalix BioTherapeutics. MarketBeat recorded 4 mentions for Olema Pharmaceuticals and 2 mentions for Protalix BioTherapeutics. Olema Pharmaceuticals' average media sentiment score of 0.39 beat Protalix BioTherapeutics' score of 0.24 indicating that Olema Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Protalix BioTherapeutics
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Olema Pharmaceuticals
1 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Protalix BioTherapeutics presently has a consensus target price of $12.00, indicating a potential upside of 346.10%. Olema Pharmaceuticals has a consensus target price of $40.60, indicating a potential upside of 313.44%. Given Protalix BioTherapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Protalix BioTherapeutics is more favorable than Olema Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Protalix BioTherapeutics
0 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
3.00
Olema Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.77

Olema Pharmaceuticals has a net margin of 0.00% compared to Protalix BioTherapeutics' net margin of -21.03%. Protalix BioTherapeutics' return on equity of -30.89% beat Olema Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Protalix BioTherapeutics-21.03% -30.89% -11.74%
Olema Pharmaceuticals N/A -48.26%-43.04%

Summary

Olema Pharmaceuticals beats Protalix BioTherapeutics on 8 of the 15 factors compared between the two stocks.

How does Protalix BioTherapeutics compare to Candel Therapeutics?

Protalix BioTherapeutics (NYSE:PLX) and Candel Therapeutics (NASDAQ:CADL) are both small-cap healthcare companies, but which is the superior stock? We will compare the two companies based on the strength of their risk, valuation, profitability, media sentiment, earnings, dividends, analyst recommendations and institutional ownership.

In the previous week, Protalix BioTherapeutics had 1 more articles in the media than Candel Therapeutics. MarketBeat recorded 2 mentions for Protalix BioTherapeutics and 1 mentions for Candel Therapeutics. Candel Therapeutics' average media sentiment score of 0.50 beat Protalix BioTherapeutics' score of 0.24 indicating that Candel Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Protalix BioTherapeutics
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Candel Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Protalix BioTherapeutics presently has a consensus price target of $12.00, suggesting a potential upside of 346.10%. Candel Therapeutics has a consensus price target of $19.29, suggesting a potential upside of 77.99%. Given Protalix BioTherapeutics' stronger consensus rating and higher possible upside, research analysts plainly believe Protalix BioTherapeutics is more favorable than Candel Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Protalix BioTherapeutics
0 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
3.00
Candel Therapeutics
1 Sell rating(s)
2 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.64

Candel Therapeutics has a net margin of 0.00% compared to Protalix BioTherapeutics' net margin of -21.03%. Protalix BioTherapeutics' return on equity of -30.89% beat Candel Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Protalix BioTherapeutics-21.03% -30.89% -11.74%
Candel Therapeutics N/A -76.98%-48.50%

16.5% of Protalix BioTherapeutics shares are owned by institutional investors. Comparatively, 13.9% of Candel Therapeutics shares are owned by institutional investors. 6.7% of Protalix BioTherapeutics shares are owned by insiders. Comparatively, 14.3% of Candel Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Protalix BioTherapeutics has higher revenue and earnings than Candel Therapeutics. Candel Therapeutics is trading at a lower price-to-earnings ratio than Protalix BioTherapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Protalix BioTherapeutics$80.62M2.69$8.31M$0.2311.70
Candel TherapeuticsN/AN/A-$38.18M-$1.41N/A

Protalix BioTherapeutics has a beta of 0.02, meaning that its share price is 98% less volatile than the broader market. Comparatively, Candel Therapeutics has a beta of -0.48, meaning that its share price is 148% less volatile than the broader market.

Summary

Protalix BioTherapeutics beats Candel Therapeutics on 10 of the 15 factors compared between the two stocks.

How does Protalix BioTherapeutics compare to Geron?

Geron (NASDAQ:GERN) and Protalix BioTherapeutics (NYSE:PLX) are both small-cap healthcare companies, but which is the superior stock? We will contrast the two companies based on the strength of their valuation, risk, earnings, institutional ownership, profitability, analyst recommendations, dividends and media sentiment.

Geron has a beta of 0.61, indicating that its share price is 39% less volatile than the broader market. Comparatively, Protalix BioTherapeutics has a beta of 0.02, indicating that its share price is 98% less volatile than the broader market.

73.7% of Geron shares are owned by institutional investors. Comparatively, 16.5% of Protalix BioTherapeutics shares are owned by institutional investors. 1.7% of Geron shares are owned by company insiders. Comparatively, 6.7% of Protalix BioTherapeutics shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

Protalix BioTherapeutics has lower revenue, but higher earnings than Geron. Geron is trading at a lower price-to-earnings ratio than Protalix BioTherapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Geron$183.88M4.54-$83.50M-$0.11N/A
Protalix BioTherapeutics$80.62M2.69$8.31M$0.2311.70

Geron currently has a consensus price target of $4.00, indicating a potential upside of 207.69%. Protalix BioTherapeutics has a consensus price target of $12.00, indicating a potential upside of 346.10%. Given Protalix BioTherapeutics' stronger consensus rating and higher possible upside, analysts clearly believe Protalix BioTherapeutics is more favorable than Geron.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Geron
1 Sell rating(s)
2 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.20
Protalix BioTherapeutics
0 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
3.00

In the previous week, Geron had 1 more articles in the media than Protalix BioTherapeutics. MarketBeat recorded 3 mentions for Geron and 2 mentions for Protalix BioTherapeutics. Protalix BioTherapeutics' average media sentiment score of 0.24 beat Geron's score of 0.13 indicating that Protalix BioTherapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Geron
0 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Protalix BioTherapeutics
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Protalix BioTherapeutics has a net margin of -21.03% compared to Geron's net margin of -34.17%. Geron's return on equity of -24.48% beat Protalix BioTherapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Geron-34.17% -24.48% -10.30%
Protalix BioTherapeutics -21.03%-30.89%-11.74%

Summary

Geron beats Protalix BioTherapeutics on 9 of the 16 factors compared between the two stocks.

How does Protalix BioTherapeutics compare to Rigel Pharmaceuticals?

Protalix BioTherapeutics (NYSE:PLX) and Rigel Pharmaceuticals (NASDAQ:RIGL) are both small-cap healthcare companies, but which is the better business? We will contrast the two businesses based on the strength of their valuation, dividends, profitability, earnings, analyst recommendations, risk, institutional ownership and media sentiment.

16.5% of Protalix BioTherapeutics shares are held by institutional investors. Comparatively, 66.2% of Rigel Pharmaceuticals shares are held by institutional investors. 6.7% of Protalix BioTherapeutics shares are held by company insiders. Comparatively, 10.5% of Rigel Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

In the previous week, Rigel Pharmaceuticals had 4 more articles in the media than Protalix BioTherapeutics. MarketBeat recorded 6 mentions for Rigel Pharmaceuticals and 2 mentions for Protalix BioTherapeutics. Rigel Pharmaceuticals' average media sentiment score of 0.42 beat Protalix BioTherapeutics' score of 0.24 indicating that Rigel Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Protalix BioTherapeutics
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Rigel Pharmaceuticals
2 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Protalix BioTherapeutics has a beta of 0.02, meaning that its stock price is 98% less volatile than the broader market. Comparatively, Rigel Pharmaceuticals has a beta of 1.2, meaning that its stock price is 20% more volatile than the broader market.

Rigel Pharmaceuticals has a net margin of 116.30% compared to Protalix BioTherapeutics' net margin of -21.03%. Rigel Pharmaceuticals' return on equity of 22.95% beat Protalix BioTherapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Protalix BioTherapeutics-21.03% -30.89% -11.74%
Rigel Pharmaceuticals 116.30%22.95%17.19%

Protalix BioTherapeutics currently has a consensus target price of $12.00, suggesting a potential upside of 346.10%. Rigel Pharmaceuticals has a consensus target price of $59.00, suggesting a potential upside of 26.50%. Given Protalix BioTherapeutics' stronger consensus rating and higher possible upside, equities analysts plainly believe Protalix BioTherapeutics is more favorable than Rigel Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Protalix BioTherapeutics
0 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
3.00
Rigel Pharmaceuticals
0 Sell rating(s)
3 Hold rating(s)
4 Buy rating(s)
0 Strong Buy rating(s)
2.57

Rigel Pharmaceuticals has higher revenue and earnings than Protalix BioTherapeutics. Rigel Pharmaceuticals is trading at a lower price-to-earnings ratio than Protalix BioTherapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Protalix BioTherapeutics$80.62M2.69$8.31M$0.2311.70
Rigel Pharmaceuticals$294.28M2.93$367.02M$16.322.86

Summary

Rigel Pharmaceuticals beats Protalix BioTherapeutics on 14 of the 16 factors compared between the two stocks.

How does Protalix BioTherapeutics compare to Climb Bio?

Protalix BioTherapeutics (NYSE:PLX) and Climb Bio (NASDAQ:CLYM) are both small-cap healthcare companies, but which is the better stock? We will contrast the two companies based on the strength of their dividends, valuation, risk, institutional ownership, analyst recommendations, media sentiment, earnings and profitability.

16.5% of Protalix BioTherapeutics shares are held by institutional investors. Comparatively, 69.8% of Climb Bio shares are held by institutional investors. 6.7% of Protalix BioTherapeutics shares are held by company insiders. Comparatively, 2.6% of Climb Bio shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

In the previous week, Climb Bio had 5 more articles in the media than Protalix BioTherapeutics. MarketBeat recorded 7 mentions for Climb Bio and 2 mentions for Protalix BioTherapeutics. Climb Bio's average media sentiment score of 0.68 beat Protalix BioTherapeutics' score of 0.24 indicating that Climb Bio is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Protalix BioTherapeutics
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Climb Bio
3 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Protalix BioTherapeutics has a beta of 0.02, indicating that its stock price is 98% less volatile than the broader market. Comparatively, Climb Bio has a beta of 0.09, indicating that its stock price is 91% less volatile than the broader market.

Climb Bio has a net margin of 0.00% compared to Protalix BioTherapeutics' net margin of -21.03%. Protalix BioTherapeutics' return on equity of -30.89% beat Climb Bio's return on equity.

Company Net Margins Return on Equity Return on Assets
Protalix BioTherapeutics-21.03% -30.89% -11.74%
Climb Bio N/A -31.79%-30.79%

Protalix BioTherapeutics has higher revenue and earnings than Climb Bio. Climb Bio is trading at a lower price-to-earnings ratio than Protalix BioTherapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Protalix BioTherapeutics$80.62M2.69$8.31M$0.2311.70
Climb BioN/AN/A-$59.85M-$0.83N/A

Protalix BioTherapeutics currently has a consensus target price of $12.00, indicating a potential upside of 346.10%. Climb Bio has a consensus target price of $26.92, indicating a potential upside of 91.62%. Given Protalix BioTherapeutics' higher possible upside, equities research analysts plainly believe Protalix BioTherapeutics is more favorable than Climb Bio.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Protalix BioTherapeutics
0 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
3.00
Climb Bio
1 Sell rating(s)
0 Hold rating(s)
13 Buy rating(s)
2 Strong Buy rating(s)
3.00

Summary

Climb Bio beats Protalix BioTherapeutics on 8 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PLX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NYSE and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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PLX vs. The Competition

MetricProtalix BioTherapeuticsBiotechnology IndustryHealthcare SectorNYSE Exchange
Market Cap$216.74M$3.89B$7.24B$23.10B
Dividend YieldN/A3.64%2.57%3.62%
P/E Ratio-20.6914.23275.4928.21
Price / Sales2.691,423.41639.5420.30
Price / Cash17.80108.9076.2536.36
Price / Book5.7215.4510.464.67
Net Income$8.31M-$22.86M$3.49B$1.07B
7 Day Performance1.89%-1.21%0.59%-1.64%
1 Month Performance13.03%-3.29%-1.74%-3.60%
1 Year Performance42.33%37.74%18.13%8.41%

Protalix BioTherapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PLX
Protalix BioTherapeutics
2.9448 of 5 stars
$2.69
-0.4%
$12.00
+346.1%
+42.3%$216.74M$80.62MN/A226
OLMA
Olema Pharmaceuticals
2.619 of 5 stars
$9.78
-5.0%
$40.60
+315.1%
+20.2%$855.73MN/AN/A150
CADL
Candel Therapeutics
3.2883 of 5 stars
$11.12
+4.1%
$19.29
+73.4%
+125.3%$850.89MN/AN/A55
GERN
Geron
1.3742 of 5 stars
$1.31
-4.4%
$4.00
+205.3%
-1.5%$841.64M$183.88MN/A258
RIGL
Rigel Pharmaceuticals
4.5337 of 5 stars
$44.36
-2.2%
$59.00
+33.0%
+34.3%$820.75M$276.79M2.72174

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This page (NYSE:PLX) was last updated on 9/20/2026 by MarketBeat.com Staff.
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