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Protalix BioTherapeutics (PLX) Competitors

Protalix BioTherapeutics logo
$2.78 +0.08 (+2.96%)
Closing price 10/9/2026 04:00 PM Eastern
Extended Trading
$2.78 +0.01 (+0.18%)
As of 10/9/2026 07:44 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

PLX vs. ODTX, RIGL, JBIO, GLUE, and SANA

Should you buy Protalix BioTherapeutics stock or one of its competitors? Protalix BioTherapeutics's main competitors and comparable companies include Odyssey Therapeutics (ODTX), Rigel Pharmaceuticals (RIGL), Jade Biosciences (JBIO), Monte Rosa Therapeutics (GLUE), and Sana Biotechnology (SANA). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Protalix BioTherapeutics compare to Odyssey Therapeutics?

Odyssey Therapeutics (NASDAQ:ODTX) and Protalix BioTherapeutics (NYSE:PLX) are both small-cap healthcare companies, but which is the better investment? We will compare the two businesses based on the strength of their earnings, institutional ownership, profitability, analyst recommendations, risk, valuation, dividends and media sentiment.

Odyssey Therapeutics has a net margin of 0.00% compared to Protalix BioTherapeutics' net margin of -21.03%. Odyssey Therapeutics' return on equity of 0.00% beat Protalix BioTherapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Odyssey TherapeuticsN/A N/A N/A
Protalix BioTherapeutics -21.03%-30.89%-11.74%

Odyssey Therapeutics presently has a consensus target price of $37.00, suggesting a potential upside of 94.74%. Protalix BioTherapeutics has a consensus target price of $12.00, suggesting a potential upside of 331.65%. Given Protalix BioTherapeutics' stronger consensus rating and higher probable upside, analysts clearly believe Protalix BioTherapeutics is more favorable than Odyssey Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Odyssey Therapeutics
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.67
Protalix BioTherapeutics
0 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
3.00

In the previous week, Odyssey Therapeutics had 7 more articles in the media than Protalix BioTherapeutics. MarketBeat recorded 8 mentions for Odyssey Therapeutics and 1 mentions for Protalix BioTherapeutics. Odyssey Therapeutics' average media sentiment score of 0.52 beat Protalix BioTherapeutics' score of 0.00 indicating that Odyssey Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Odyssey Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Protalix BioTherapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

16.5% of Protalix BioTherapeutics shares are held by institutional investors. 6.7% of Protalix BioTherapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Protalix BioTherapeutics has higher revenue and earnings than Odyssey Therapeutics. Odyssey Therapeutics is trading at a lower price-to-earnings ratio than Protalix BioTherapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Odyssey TherapeuticsN/AN/AN/A-$6.77N/A
Protalix BioTherapeutics$80.62M2.78$8.31M$0.2312.09

Summary

Odyssey Therapeutics beats Protalix BioTherapeutics on 7 of the 13 factors compared between the two stocks.

How does Protalix BioTherapeutics compare to Rigel Pharmaceuticals?

Rigel Pharmaceuticals (NASDAQ:RIGL) and Protalix BioTherapeutics (NYSE:PLX) are both small-cap healthcare companies, but which is the superior investment? We will compare the two businesses based on the strength of their earnings, risk, institutional ownership, dividends, profitability, valuation, media sentiment and analyst recommendations.

Rigel Pharmaceuticals presently has a consensus target price of $59.00, suggesting a potential upside of 20.21%. Protalix BioTherapeutics has a consensus target price of $12.00, suggesting a potential upside of 331.65%. Given Protalix BioTherapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Protalix BioTherapeutics is more favorable than Rigel Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Rigel Pharmaceuticals
0 Sell rating(s)
3 Hold rating(s)
4 Buy rating(s)
0 Strong Buy rating(s)
2.57
Protalix BioTherapeutics
0 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
3.00

In the previous week, Rigel Pharmaceuticals had 1 more articles in the media than Protalix BioTherapeutics. MarketBeat recorded 2 mentions for Rigel Pharmaceuticals and 1 mentions for Protalix BioTherapeutics. Rigel Pharmaceuticals' average media sentiment score of 0.89 beat Protalix BioTherapeutics' score of 0.00 indicating that Rigel Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Rigel Pharmaceuticals
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Protalix BioTherapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Rigel Pharmaceuticals has a beta of 1.19, indicating that its stock price is 19% more volatile than the broader market. Comparatively, Protalix BioTherapeutics has a beta of -0.09, indicating that its stock price is 109% less volatile than the broader market.

Rigel Pharmaceuticals has higher revenue and earnings than Protalix BioTherapeutics. Rigel Pharmaceuticals is trading at a lower price-to-earnings ratio than Protalix BioTherapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Rigel Pharmaceuticals$294.28M3.09$367.02M$16.323.01
Protalix BioTherapeutics$80.62M2.78$8.31M$0.2312.09

Rigel Pharmaceuticals has a net margin of 116.30% compared to Protalix BioTherapeutics' net margin of -21.03%. Rigel Pharmaceuticals' return on equity of 22.95% beat Protalix BioTherapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Rigel Pharmaceuticals116.30% 22.95% 17.19%
Protalix BioTherapeutics -21.03%-30.89%-11.74%

66.2% of Rigel Pharmaceuticals shares are owned by institutional investors. Comparatively, 16.5% of Protalix BioTherapeutics shares are owned by institutional investors. 10.5% of Rigel Pharmaceuticals shares are owned by insiders. Comparatively, 6.7% of Protalix BioTherapeutics shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

Summary

Rigel Pharmaceuticals beats Protalix BioTherapeutics on 14 of the 16 factors compared between the two stocks.

How does Protalix BioTherapeutics compare to Jade Biosciences?

Jade Biosciences (NASDAQ:JBIO) and Protalix BioTherapeutics (NYSE:PLX) are both small-cap healthcare companies, but which is the superior business? We will contrast the two companies based on the strength of their profitability, earnings, analyst recommendations, media sentiment, institutional ownership, dividends, valuation and risk.

In the previous week, Jade Biosciences had 1 more articles in the media than Protalix BioTherapeutics. MarketBeat recorded 2 mentions for Jade Biosciences and 1 mentions for Protalix BioTherapeutics. Jade Biosciences' average media sentiment score of 0.61 beat Protalix BioTherapeutics' score of 0.00 indicating that Jade Biosciences is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Jade Biosciences
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Protalix BioTherapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Protalix BioTherapeutics has higher revenue and earnings than Jade Biosciences. Jade Biosciences is trading at a lower price-to-earnings ratio than Protalix BioTherapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Jade BiosciencesN/AN/A-$127.41M-$1.92N/A
Protalix BioTherapeutics$80.62M2.78$8.31M$0.2312.09

Jade Biosciences has a beta of 1.64, suggesting that its share price is 64% more volatile than the broader market. Comparatively, Protalix BioTherapeutics has a beta of -0.09, suggesting that its share price is 109% less volatile than the broader market.

Jade Biosciences presently has a consensus target price of $51.75, suggesting a potential upside of 259.62%. Protalix BioTherapeutics has a consensus target price of $12.00, suggesting a potential upside of 331.65%. Given Protalix BioTherapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Protalix BioTherapeutics is more favorable than Jade Biosciences.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Jade Biosciences
1 Sell rating(s)
1 Hold rating(s)
6 Buy rating(s)
2 Strong Buy rating(s)
2.90
Protalix BioTherapeutics
0 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
3.00

Jade Biosciences has a net margin of 0.00% compared to Protalix BioTherapeutics' net margin of -21.03%. Protalix BioTherapeutics' return on equity of -30.89% beat Jade Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Jade BiosciencesN/A -49.11% -45.62%
Protalix BioTherapeutics -21.03%-30.89%-11.74%

16.5% of Protalix BioTherapeutics shares are owned by institutional investors. 23.1% of Jade Biosciences shares are owned by insiders. Comparatively, 6.7% of Protalix BioTherapeutics shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Summary

Jade Biosciences and Protalix BioTherapeutics tied by winning 8 of the 16 factors compared between the two stocks.

How does Protalix BioTherapeutics compare to Monte Rosa Therapeutics?

Monte Rosa Therapeutics (NASDAQ:GLUE) and Protalix BioTherapeutics (NYSE:PLX) are both small-cap healthcare companies, but which is the better investment? We will compare the two companies based on the strength of their risk, media sentiment, valuation, dividends, analyst recommendations, earnings, profitability and institutional ownership.

Protalix BioTherapeutics has a net margin of -21.03% compared to Monte Rosa Therapeutics' net margin of -560.85%. Protalix BioTherapeutics' return on equity of -30.89% beat Monte Rosa Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Monte Rosa Therapeutics-560.85% -43.31% -27.59%
Protalix BioTherapeutics -21.03%-30.89%-11.74%

Protalix BioTherapeutics has lower revenue, but higher earnings than Monte Rosa Therapeutics. Monte Rosa Therapeutics is trading at a lower price-to-earnings ratio than Protalix BioTherapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Monte Rosa Therapeutics$123.67M7.11-$38.63M-$1.76N/A
Protalix BioTherapeutics$80.62M2.78$8.31M$0.2312.09

Monte Rosa Therapeutics presently has a consensus target price of $27.63, indicating a potential upside of 168.20%. Protalix BioTherapeutics has a consensus target price of $12.00, indicating a potential upside of 331.65%. Given Protalix BioTherapeutics' stronger consensus rating and higher possible upside, analysts clearly believe Protalix BioTherapeutics is more favorable than Monte Rosa Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Monte Rosa Therapeutics
1 Sell rating(s)
1 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.82
Protalix BioTherapeutics
0 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
3.00

In the previous week, Monte Rosa Therapeutics had 8 more articles in the media than Protalix BioTherapeutics. MarketBeat recorded 9 mentions for Monte Rosa Therapeutics and 1 mentions for Protalix BioTherapeutics. Monte Rosa Therapeutics' average media sentiment score of 0.59 beat Protalix BioTherapeutics' score of 0.00 indicating that Monte Rosa Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Monte Rosa Therapeutics
1 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
2 Very Negative mention(s)
Positive
Protalix BioTherapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Monte Rosa Therapeutics has a beta of 1.37, indicating that its share price is 37% more volatile than the broader market. Comparatively, Protalix BioTherapeutics has a beta of -0.09, indicating that its share price is 109% less volatile than the broader market.

80.0% of Monte Rosa Therapeutics shares are held by institutional investors. Comparatively, 16.5% of Protalix BioTherapeutics shares are held by institutional investors. 6.4% of Monte Rosa Therapeutics shares are held by insiders. Comparatively, 6.7% of Protalix BioTherapeutics shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

Summary

Monte Rosa Therapeutics beats Protalix BioTherapeutics on 9 of the 17 factors compared between the two stocks.

How does Protalix BioTherapeutics compare to Sana Biotechnology?

Sana Biotechnology (NASDAQ:SANA) and Protalix BioTherapeutics (NYSE:PLX) are both small-cap healthcare companies, but which is the superior investment? We will contrast the two businesses based on the strength of their media sentiment, institutional ownership, risk, dividends, analyst recommendations, profitability, earnings and valuation.

Protalix BioTherapeutics has higher revenue and earnings than Sana Biotechnology. Sana Biotechnology is trading at a lower price-to-earnings ratio than Protalix BioTherapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Sana BiotechnologyN/AN/A-$244.17M-$0.76N/A
Protalix BioTherapeutics$80.62M2.78$8.31M$0.2312.09

Sana Biotechnology has a net margin of 0.00% compared to Protalix BioTherapeutics' net margin of -21.03%. Protalix BioTherapeutics' return on equity of -30.89% beat Sana Biotechnology's return on equity.

Company Net Margins Return on Equity Return on Assets
Sana BiotechnologyN/A -103.02% -39.16%
Protalix BioTherapeutics -21.03%-30.89%-11.74%

In the previous week, Sana Biotechnology had 2 more articles in the media than Protalix BioTherapeutics. MarketBeat recorded 3 mentions for Sana Biotechnology and 1 mentions for Protalix BioTherapeutics. Sana Biotechnology's average media sentiment score of 1.08 beat Protalix BioTherapeutics' score of 0.00 indicating that Sana Biotechnology is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Sana Biotechnology
2 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Protalix BioTherapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Sana Biotechnology has a beta of 2.18, meaning that its share price is 118% more volatile than the broader market. Comparatively, Protalix BioTherapeutics has a beta of -0.09, meaning that its share price is 109% less volatile than the broader market.

88.2% of Sana Biotechnology shares are owned by institutional investors. Comparatively, 16.5% of Protalix BioTherapeutics shares are owned by institutional investors. 25.4% of Sana Biotechnology shares are owned by company insiders. Comparatively, 6.7% of Protalix BioTherapeutics shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Sana Biotechnology presently has a consensus target price of $9.33, indicating a potential upside of 234.53%. Protalix BioTherapeutics has a consensus target price of $12.00, indicating a potential upside of 331.65%. Given Protalix BioTherapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Protalix BioTherapeutics is more favorable than Sana Biotechnology.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Sana Biotechnology
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.80
Protalix BioTherapeutics
0 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
3.00

Summary

Sana Biotechnology beats Protalix BioTherapeutics on 9 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PLX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NYSE and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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PLX vs. The Competition

MetricProtalix BioTherapeuticsBiotechnology IndustryHealthcare SectorNYSE Exchange
Market Cap$223.99M$3.93B$7.25B$23.07B
Dividend YieldN/A3.64%2.52%3.72%
P/E Ratio-21.3813.55275.0128.58
Price / Sales2.781,209.42582.8520.72
Price / Cash17.80119.4976.9638.93
Price / Book5.9117.1711.224.72
Net Income$8.31M-$22.69M$3.50B$1.07B
7 Day Performance2.58%-1.34%-0.89%0.35%
1 Month Performance5.30%-8.04%-4.02%-3.40%
1 Year Performance17.80%14.18%7.13%9.40%

Protalix BioTherapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PLX
Protalix BioTherapeutics
2.3641 of 5 stars
$2.78
+3.0%
$12.00
+331.7%
+17.8%$223.99M$80.62MN/A226
ODTX
Odyssey Therapeutics
2.8952 of 5 stars
$18.13
-13.0%
$35.75
+97.2%
N/A$871.31M$99KN/A100
RIGL
Rigel Pharmaceuticals
4.2957 of 5 stars
$46.11
-3.5%
$59.00
+28.0%
+74.2%$853.13M$276.79M2.83174
JBIO
Jade Biosciences
1.8452 of 5 stars
$13.41
-4.7%
$51.75
+285.9%
+58.5%$852.88MN/AN/A55
GLUE
Monte Rosa Therapeutics
2.3866 of 5 stars
$9.87
-3.9%
$27.63
+179.9%
+2.6%$842.01M$123.67MN/A173

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This page (NYSE:PLX) was last updated on 10/11/2026 by MarketBeat.com Staff.
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