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Oruka Therapeutics (ORKA) Competitors

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$69.89 +1.42 (+2.07%)
Closing price 06/12/2026 04:00 PM Eastern
Extended Trading
$69.56 -0.33 (-0.47%)
As of 06/12/2026 07:49 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

ORKA vs. ASND, BBIO, ELAN, AXSM, and SMMT

Should you buy Oruka Therapeutics stock or one of its competitors? MarketBeat compares Oruka Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Oruka Therapeutics include Ascendis Pharma A/S (ASND), BridgeBio Pharma (BBIO), Elanco Animal Health (ELAN), Axsome Therapeutics (AXSM), and Summit Therapeutics (SMMT). These companies are all part of the "pharmaceutical products" industry.

How does Oruka Therapeutics compare to Ascendis Pharma A/S?

Oruka Therapeutics (NASDAQ:ORKA) and Ascendis Pharma A/S (NASDAQ:ASND) are both medical companies, but which is the superior business? We will compare the two companies based on the strength of their media sentiment, valuation, dividends, analyst recommendations, risk, profitability, institutional ownership and earnings.

In the previous week, Ascendis Pharma A/S had 8 more articles in the media than Oruka Therapeutics. MarketBeat recorded 13 mentions for Ascendis Pharma A/S and 5 mentions for Oruka Therapeutics. Ascendis Pharma A/S's average media sentiment score of 1.10 beat Oruka Therapeutics' score of 0.19 indicating that Ascendis Pharma A/S is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Oruka Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
Ascendis Pharma A/S
7 Very Positive mention(s)
1 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Ascendis Pharma A/S has a net margin of 57.87% compared to Oruka Therapeutics' net margin of 0.00%. Ascendis Pharma A/S's return on equity of 0.00% beat Oruka Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Oruka TherapeuticsN/A -26.16% -25.00%
Ascendis Pharma A/S 57.87%N/A -8.37%

Oruka Therapeutics presently has a consensus target price of $131.30, suggesting a potential upside of 87.87%. Ascendis Pharma A/S has a consensus target price of $295.39, suggesting a potential upside of 35.46%. Given Oruka Therapeutics' higher possible upside, equities analysts clearly believe Oruka Therapeutics is more favorable than Ascendis Pharma A/S.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Oruka Therapeutics
1 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.82
Ascendis Pharma A/S
1 Sell rating(s)
0 Hold rating(s)
16 Buy rating(s)
2 Strong Buy rating(s)
3.00

56.4% of Oruka Therapeutics shares are owned by institutional investors. 23.5% of Oruka Therapeutics shares are owned by insiders. Comparatively, 40.0% of Ascendis Pharma A/S shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Oruka Therapeutics has higher earnings, but lower revenue than Ascendis Pharma A/S. Oruka Therapeutics is trading at a lower price-to-earnings ratio than Ascendis Pharma A/S, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Oruka TherapeuticsN/AN/A-$105.43M-$1.94N/A
Ascendis Pharma A/S$814.57M16.70-$258M$8.6725.15

Oruka Therapeutics has a beta of -0.25, indicating that its share price is 125% less volatile than the broader market. Comparatively, Ascendis Pharma A/S has a beta of 0.39, indicating that its share price is 61% less volatile than the broader market.

Summary

Ascendis Pharma A/S beats Oruka Therapeutics on 13 of the 16 factors compared between the two stocks.

How does Oruka Therapeutics compare to BridgeBio Pharma?

Oruka Therapeutics (NASDAQ:ORKA) and BridgeBio Pharma (NASDAQ:BBIO) are both medical companies, but which is the superior investment? We will compare the two companies based on the strength of their risk, analyst recommendations, valuation, profitability, media sentiment, dividends, institutional ownership and earnings.

Oruka Therapeutics currently has a consensus price target of $131.30, suggesting a potential upside of 87.87%. BridgeBio Pharma has a consensus price target of $89.59, suggesting a potential upside of 34.12%. Given Oruka Therapeutics' higher probable upside, equities research analysts clearly believe Oruka Therapeutics is more favorable than BridgeBio Pharma.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Oruka Therapeutics
1 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.82
BridgeBio Pharma
1 Sell rating(s)
2 Hold rating(s)
23 Buy rating(s)
0 Strong Buy rating(s)
2.85

In the previous week, BridgeBio Pharma had 8 more articles in the media than Oruka Therapeutics. MarketBeat recorded 13 mentions for BridgeBio Pharma and 5 mentions for Oruka Therapeutics. BridgeBio Pharma's average media sentiment score of 1.19 beat Oruka Therapeutics' score of 0.19 indicating that BridgeBio Pharma is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Oruka Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
BridgeBio Pharma
10 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

56.4% of Oruka Therapeutics shares are owned by institutional investors. Comparatively, 99.9% of BridgeBio Pharma shares are owned by institutional investors. 23.5% of Oruka Therapeutics shares are owned by company insiders. Comparatively, 14.2% of BridgeBio Pharma shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

Oruka Therapeutics has a net margin of 0.00% compared to BridgeBio Pharma's net margin of -124.42%. BridgeBio Pharma's return on equity of 0.00% beat Oruka Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Oruka TherapeuticsN/A -26.16% -25.00%
BridgeBio Pharma -124.42%N/A -65.81%

Oruka Therapeutics has a beta of -0.25, indicating that its stock price is 125% less volatile than the broader market. Comparatively, BridgeBio Pharma has a beta of 0.98, indicating that its stock price is 2% less volatile than the broader market.

Oruka Therapeutics has higher earnings, but lower revenue than BridgeBio Pharma. Oruka Therapeutics is trading at a lower price-to-earnings ratio than BridgeBio Pharma, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Oruka TherapeuticsN/AN/A-$105.43M-$1.94N/A
BridgeBio Pharma$502.08M26.06-$724.93M-$3.74N/A

Summary

BridgeBio Pharma beats Oruka Therapeutics on 9 of the 15 factors compared between the two stocks.

How does Oruka Therapeutics compare to Elanco Animal Health?

Oruka Therapeutics (NASDAQ:ORKA) and Elanco Animal Health (NYSE:ELAN) are both medical companies, but which is the better investment? We will contrast the two businesses based on the strength of their profitability, valuation, dividends, institutional ownership, risk, earnings, analyst recommendations and media sentiment.

Oruka Therapeutics has a net margin of 0.00% compared to Elanco Animal Health's net margin of -4.95%. Elanco Animal Health's return on equity of 7.42% beat Oruka Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Oruka TherapeuticsN/A -26.16% -25.00%
Elanco Animal Health -4.95%7.42%3.66%

Oruka Therapeutics has a beta of -0.25, meaning that its share price is 125% less volatile than the broader market. Comparatively, Elanco Animal Health has a beta of 1.69, meaning that its share price is 69% more volatile than the broader market.

Oruka Therapeutics presently has a consensus price target of $131.30, indicating a potential upside of 87.87%. Elanco Animal Health has a consensus price target of $28.20, indicating a potential upside of 16.56%. Given Oruka Therapeutics' stronger consensus rating and higher probable upside, equities analysts clearly believe Oruka Therapeutics is more favorable than Elanco Animal Health.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Oruka Therapeutics
1 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.82
Elanco Animal Health
1 Sell rating(s)
2 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.77

Oruka Therapeutics has higher earnings, but lower revenue than Elanco Animal Health. Elanco Animal Health is trading at a lower price-to-earnings ratio than Oruka Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Oruka TherapeuticsN/AN/A-$105.43M-$1.94N/A
Elanco Animal Health$4.72B2.56-$232M-$0.50N/A

In the previous week, Elanco Animal Health had 3 more articles in the media than Oruka Therapeutics. MarketBeat recorded 8 mentions for Elanco Animal Health and 5 mentions for Oruka Therapeutics. Elanco Animal Health's average media sentiment score of 1.19 beat Oruka Therapeutics' score of 0.19 indicating that Elanco Animal Health is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Oruka Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
Elanco Animal Health
6 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

56.4% of Oruka Therapeutics shares are held by institutional investors. Comparatively, 97.5% of Elanco Animal Health shares are held by institutional investors. 23.5% of Oruka Therapeutics shares are held by insiders. Comparatively, 1.1% of Elanco Animal Health shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

Summary

Elanco Animal Health beats Oruka Therapeutics on 9 of the 16 factors compared between the two stocks.

How does Oruka Therapeutics compare to Axsome Therapeutics?

Axsome Therapeutics (NASDAQ:AXSM) and Oruka Therapeutics (NASDAQ:ORKA) are both medical companies, but which is the better investment? We will contrast the two businesses based on the strength of their earnings, institutional ownership, dividends, risk, valuation, profitability, analyst recommendations and media sentiment.

Oruka Therapeutics has lower revenue, but higher earnings than Axsome Therapeutics. Axsome Therapeutics is trading at a lower price-to-earnings ratio than Oruka Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Axsome Therapeutics$638.50M20.57-$183.17M-$3.73N/A
Oruka TherapeuticsN/AN/A-$105.43M-$1.94N/A

Axsome Therapeutics presently has a consensus target price of $256.79, indicating a potential upside of 0.63%. Oruka Therapeutics has a consensus target price of $131.30, indicating a potential upside of 87.87%. Given Oruka Therapeutics' higher possible upside, analysts clearly believe Oruka Therapeutics is more favorable than Axsome Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Axsome Therapeutics
1 Sell rating(s)
0 Hold rating(s)
19 Buy rating(s)
1 Strong Buy rating(s)
2.95
Oruka Therapeutics
1 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.82

In the previous week, Axsome Therapeutics had 17 more articles in the media than Oruka Therapeutics. MarketBeat recorded 22 mentions for Axsome Therapeutics and 5 mentions for Oruka Therapeutics. Axsome Therapeutics' average media sentiment score of 0.67 beat Oruka Therapeutics' score of 0.19 indicating that Axsome Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Axsome Therapeutics
12 Very Positive mention(s)
3 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Oruka Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

81.5% of Axsome Therapeutics shares are owned by institutional investors. Comparatively, 56.4% of Oruka Therapeutics shares are owned by institutional investors. 20.6% of Axsome Therapeutics shares are owned by insiders. Comparatively, 23.5% of Oruka Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Axsome Therapeutics has a beta of 0.61, suggesting that its share price is 39% less volatile than the broader market. Comparatively, Oruka Therapeutics has a beta of -0.25, suggesting that its share price is 125% less volatile than the broader market.

Oruka Therapeutics has a net margin of 0.00% compared to Axsome Therapeutics' net margin of -26.59%. Oruka Therapeutics' return on equity of -26.16% beat Axsome Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Axsome Therapeutics-26.59% -267.16% -28.53%
Oruka Therapeutics N/A -26.16%-25.00%

Summary

Axsome Therapeutics and Oruka Therapeutics tied by winning 8 of the 16 factors compared between the two stocks.

How does Oruka Therapeutics compare to Summit Therapeutics?

Summit Therapeutics (NASDAQ:SMMT) and Oruka Therapeutics (NASDAQ:ORKA) are both medical companies, but which is the superior stock? We will contrast the two businesses based on the strength of their earnings, dividends, institutional ownership, media sentiment, risk, profitability, analyst recommendations and valuation.

In the previous week, Summit Therapeutics had 8 more articles in the media than Oruka Therapeutics. MarketBeat recorded 13 mentions for Summit Therapeutics and 5 mentions for Oruka Therapeutics. Summit Therapeutics' average media sentiment score of 0.84 beat Oruka Therapeutics' score of 0.19 indicating that Summit Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Summit Therapeutics
4 Very Positive mention(s)
2 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Oruka Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

4.6% of Summit Therapeutics shares are owned by institutional investors. Comparatively, 56.4% of Oruka Therapeutics shares are owned by institutional investors. 83.5% of Summit Therapeutics shares are owned by company insiders. Comparatively, 23.5% of Oruka Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

Summit Therapeutics currently has a consensus price target of $27.23, indicating a potential upside of 94.33%. Oruka Therapeutics has a consensus price target of $131.30, indicating a potential upside of 87.87%. Given Summit Therapeutics' higher possible upside, research analysts clearly believe Summit Therapeutics is more favorable than Oruka Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Summit Therapeutics
2 Sell rating(s)
6 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.47
Oruka Therapeutics
1 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.82

Oruka Therapeutics' return on equity of -26.16% beat Summit Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Summit TherapeuticsN/A -291.24% -243.07%
Oruka Therapeutics N/A -26.16%-25.00%

Summit Therapeutics has a beta of -1.32, suggesting that its share price is 232% less volatile than the broader market. Comparatively, Oruka Therapeutics has a beta of -0.25, suggesting that its share price is 125% less volatile than the broader market.

Oruka Therapeutics is trading at a lower price-to-earnings ratio than Summit Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Summit TherapeuticsN/AN/A-$1.08B-$1.60N/A
Oruka TherapeuticsN/AN/A-$105.43M-$1.94N/A

Summary

Summit Therapeutics and Oruka Therapeutics tied by winning 7 of the 14 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding ORKA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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ORKA vs. The Competition

MetricOruka TherapeuticsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$4.22B$3.01B$6.74B$12.07B
Dividend YieldN/A1.76%2.67%5.67%
P/E Ratio-36.0318.8424.2124.42
Price / SalesN/A309.12512.04109.94
Price / CashN/A55.8827.4837.92
Price / Book7.213.9810.666.83
Net Income-$105.43M$75.79M$3.57B$337.67M
7 Day Performance16.21%1.19%0.84%2.68%
1 Month Performance9.37%-3.70%-0.34%1.56%
1 Year Performance456.45%23.44%25.40%30.59%

Oruka Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
ORKA
Oruka Therapeutics
2.7322 of 5 stars
$69.89
+2.1%
$131.30
+87.9%
+456.4%$4.22BN/AN/AN/A
ASND
Ascendis Pharma A/S
4.5437 of 5 stars
$210.45
-3.8%
$295.39
+40.4%
+27.7%$13.65B$814.57M24.271,189
BBIO
BridgeBio Pharma
3.6444 of 5 stars
$67.61
+0.4%
$89.59
+32.5%
+67.9%$13.19B$502.08MN/A400
ELAN
Elanco Animal Health
3.5563 of 5 stars
$23.61
-4.4%
$28.20
+19.4%
+75.1%$12.34B$4.72BN/A9,400
AXSM
Axsome Therapeutics
1.668 of 5 stars
$232.32
+0.4%
$251.26
+8.2%
+145.1%$11.91B$638.50MN/A380

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This page (NASDAQ:ORKA) was last updated on 6/14/2026 by MarketBeat.com Staff.
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