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Oruka Therapeutics (ORKA) Competitors

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$92.16 +0.21 (+0.23%)
Closing price 07/24/2026 04:00 PM Eastern
Extended Trading
$91.68 -0.48 (-0.52%)
As of 07/24/2026 07:34 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

ORKA vs. GMAB, ASND, BBIO, ELAN, and AXSM

Should you buy Oruka Therapeutics stock or one of its competitors? MarketBeat compares Oruka Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Oruka Therapeutics include Genmab A/S (GMAB), Ascendis Pharma A/S (ASND), BridgeBio Pharma (BBIO), Elanco Animal Health (ELAN), and Axsome Therapeutics (AXSM). These companies are all part of the "pharmaceutical products" industry.

How does Oruka Therapeutics compare to Genmab A/S?

Genmab A/S (NASDAQ:GMAB) and Oruka Therapeutics (NASDAQ:ORKA) are both medical companies, but which is the better stock? We will contrast the two businesses based on the strength of their profitability, dividends, earnings, media sentiment, valuation, risk, analyst recommendations and institutional ownership.

Genmab A/S has higher revenue and earnings than Oruka Therapeutics. Oruka Therapeutics is trading at a lower price-to-earnings ratio than Genmab A/S, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Genmab A/S$3.90B4.61$963M$1.3221.87
Oruka TherapeuticsN/AN/A-$105.43M-$1.94N/A

Genmab A/S has a net margin of 21.05% compared to Oruka Therapeutics' net margin of 0.00%. Genmab A/S's return on equity of 15.34% beat Oruka Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Genmab A/S21.05% 15.34% 8.94%
Oruka Therapeutics N/A -26.16%-25.00%

7.1% of Genmab A/S shares are held by institutional investors. Comparatively, 56.4% of Oruka Therapeutics shares are held by institutional investors. 1.5% of Genmab A/S shares are held by company insiders. Comparatively, 23.5% of Oruka Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

In the previous week, Genmab A/S had 1 more articles in the media than Oruka Therapeutics. MarketBeat recorded 6 mentions for Genmab A/S and 5 mentions for Oruka Therapeutics. Oruka Therapeutics' average media sentiment score of 1.45 beat Genmab A/S's score of 1.03 indicating that Oruka Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Genmab A/S
2 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Oruka Therapeutics
4 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Genmab A/S has a beta of 0.84, suggesting that its stock price is 16% less volatile than the broader market. Comparatively, Oruka Therapeutics has a beta of -0.35, suggesting that its stock price is 135% less volatile than the broader market.

Genmab A/S currently has a consensus price target of $39.28, indicating a potential upside of 36.05%. Oruka Therapeutics has a consensus price target of $134.30, indicating a potential upside of 45.72%. Given Oruka Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Oruka Therapeutics is more favorable than Genmab A/S.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Genmab A/S
1 Sell rating(s)
2 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.77
Oruka Therapeutics
1 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.82

Summary

Genmab A/S beats Oruka Therapeutics on 10 of the 16 factors compared between the two stocks.

How does Oruka Therapeutics compare to Ascendis Pharma A/S?

Oruka Therapeutics (NASDAQ:ORKA) and Ascendis Pharma A/S (NASDAQ:ASND) are both medical companies, but which is the better business? We will compare the two businesses based on the strength of their analyst recommendations, valuation, profitability, media sentiment, risk, dividends, earnings and institutional ownership.

Oruka Therapeutics presently has a consensus target price of $134.30, indicating a potential upside of 45.72%. Ascendis Pharma A/S has a consensus target price of $296.72, indicating a potential upside of 16.88%. Given Oruka Therapeutics' higher probable upside, equities research analysts clearly believe Oruka Therapeutics is more favorable than Ascendis Pharma A/S.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Oruka Therapeutics
1 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.82
Ascendis Pharma A/S
0 Sell rating(s)
1 Hold rating(s)
16 Buy rating(s)
2 Strong Buy rating(s)
3.05

56.4% of Oruka Therapeutics shares are held by institutional investors. 23.5% of Oruka Therapeutics shares are held by insiders. Comparatively, 40.0% of Ascendis Pharma A/S shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Oruka Therapeutics has a beta of -0.35, indicating that its share price is 135% less volatile than the broader market. Comparatively, Ascendis Pharma A/S has a beta of 0.37, indicating that its share price is 63% less volatile than the broader market.

Ascendis Pharma A/S has a net margin of 57.87% compared to Oruka Therapeutics' net margin of 0.00%. Ascendis Pharma A/S's return on equity of 0.00% beat Oruka Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Oruka TherapeuticsN/A -26.16% -25.00%
Ascendis Pharma A/S 57.87%N/A -8.37%

Oruka Therapeutics has higher earnings, but lower revenue than Ascendis Pharma A/S. Oruka Therapeutics is trading at a lower price-to-earnings ratio than Ascendis Pharma A/S, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Oruka TherapeuticsN/AN/A-$105.43M-$1.94N/A
Ascendis Pharma A/S$814.57M19.44-$258M$8.6729.28

In the previous week, Ascendis Pharma A/S had 2 more articles in the media than Oruka Therapeutics. MarketBeat recorded 7 mentions for Ascendis Pharma A/S and 5 mentions for Oruka Therapeutics. Oruka Therapeutics' average media sentiment score of 1.45 beat Ascendis Pharma A/S's score of 1.27 indicating that Oruka Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Oruka Therapeutics
4 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Ascendis Pharma A/S
6 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Ascendis Pharma A/S beats Oruka Therapeutics on 12 of the 16 factors compared between the two stocks.

How does Oruka Therapeutics compare to BridgeBio Pharma?

Oruka Therapeutics (NASDAQ:ORKA) and BridgeBio Pharma (NASDAQ:BBIO) are both medical companies, but which is the superior stock? We will compare the two businesses based on the strength of their institutional ownership, valuation, risk, media sentiment, profitability, dividends, earnings and analyst recommendations.

In the previous week, BridgeBio Pharma had 5 more articles in the media than Oruka Therapeutics. MarketBeat recorded 10 mentions for BridgeBio Pharma and 5 mentions for Oruka Therapeutics. BridgeBio Pharma's average media sentiment score of 1.50 beat Oruka Therapeutics' score of 1.45 indicating that BridgeBio Pharma is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Oruka Therapeutics
4 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
BridgeBio Pharma
8 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive

56.4% of Oruka Therapeutics shares are owned by institutional investors. Comparatively, 99.8% of BridgeBio Pharma shares are owned by institutional investors. 23.5% of Oruka Therapeutics shares are owned by insiders. Comparatively, 14.2% of BridgeBio Pharma shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Oruka Therapeutics has higher earnings, but lower revenue than BridgeBio Pharma. Oruka Therapeutics is trading at a lower price-to-earnings ratio than BridgeBio Pharma, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Oruka TherapeuticsN/AN/A-$105.43M-$1.94N/A
BridgeBio Pharma$579.96M28.37-$724.93M-$3.74N/A

Oruka Therapeutics has a beta of -0.35, meaning that its share price is 135% less volatile than the broader market. Comparatively, BridgeBio Pharma has a beta of 0.95, meaning that its share price is 5% less volatile than the broader market.

Oruka Therapeutics currently has a consensus target price of $134.30, suggesting a potential upside of 45.72%. BridgeBio Pharma has a consensus target price of $95.21, suggesting a potential upside of 13.32%. Given Oruka Therapeutics' higher possible upside, equities analysts plainly believe Oruka Therapeutics is more favorable than BridgeBio Pharma.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Oruka Therapeutics
1 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.82
BridgeBio Pharma
1 Sell rating(s)
2 Hold rating(s)
20 Buy rating(s)
0 Strong Buy rating(s)
2.83

Oruka Therapeutics has a net margin of 0.00% compared to BridgeBio Pharma's net margin of -124.42%. BridgeBio Pharma's return on equity of 0.00% beat Oruka Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Oruka TherapeuticsN/A -26.16% -25.00%
BridgeBio Pharma -124.42%N/A -65.81%

Summary

BridgeBio Pharma beats Oruka Therapeutics on 9 of the 15 factors compared between the two stocks.

How does Oruka Therapeutics compare to Elanco Animal Health?

Oruka Therapeutics (NASDAQ:ORKA) and Elanco Animal Health (NYSE:ELAN) are both medical companies, but which is the better investment? We will compare the two businesses based on the strength of their institutional ownership, media sentiment, dividends, valuation, risk, profitability, earnings and analyst recommendations.

56.4% of Oruka Therapeutics shares are owned by institutional investors. Comparatively, 97.5% of Elanco Animal Health shares are owned by institutional investors. 23.5% of Oruka Therapeutics shares are owned by company insiders. Comparatively, 1.1% of Elanco Animal Health shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Oruka Therapeutics has a beta of -0.35, meaning that its stock price is 135% less volatile than the broader market. Comparatively, Elanco Animal Health has a beta of 1.68, meaning that its stock price is 68% more volatile than the broader market.

Oruka Therapeutics has a net margin of 0.00% compared to Elanco Animal Health's net margin of -4.95%. Elanco Animal Health's return on equity of 7.42% beat Oruka Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Oruka TherapeuticsN/A -26.16% -25.00%
Elanco Animal Health -4.95%7.42%3.66%

In the previous week, Elanco Animal Health had 4 more articles in the media than Oruka Therapeutics. MarketBeat recorded 9 mentions for Elanco Animal Health and 5 mentions for Oruka Therapeutics. Oruka Therapeutics' average media sentiment score of 1.45 beat Elanco Animal Health's score of 1.27 indicating that Oruka Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Oruka Therapeutics
4 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Elanco Animal Health
6 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Oruka Therapeutics has higher earnings, but lower revenue than Elanco Animal Health. Elanco Animal Health is trading at a lower price-to-earnings ratio than Oruka Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Oruka TherapeuticsN/AN/A-$105.43M-$1.94N/A
Elanco Animal Health$4.89B2.54-$232M-$0.50N/A

Oruka Therapeutics presently has a consensus price target of $134.30, suggesting a potential upside of 45.72%. Elanco Animal Health has a consensus price target of $28.73, suggesting a potential upside of 15.37%. Given Oruka Therapeutics' stronger consensus rating and higher probable upside, equities research analysts plainly believe Oruka Therapeutics is more favorable than Elanco Animal Health.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Oruka Therapeutics
1 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.82
Elanco Animal Health
1 Sell rating(s)
2 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.77

Summary

Oruka Therapeutics and Elanco Animal Health tied by winning 8 of the 16 factors compared between the two stocks.

How does Oruka Therapeutics compare to Axsome Therapeutics?

Oruka Therapeutics (NASDAQ:ORKA) and Axsome Therapeutics (NASDAQ:AXSM) are both medical companies, but which is the better stock? We will compare the two companies based on the strength of their institutional ownership, risk, valuation, profitability, media sentiment, earnings, analyst recommendations and dividends.

Oruka Therapeutics has a beta of -0.35, meaning that its stock price is 135% less volatile than the broader market. Comparatively, Axsome Therapeutics has a beta of 0.6, meaning that its stock price is 40% less volatile than the broader market.

56.4% of Oruka Therapeutics shares are owned by institutional investors. Comparatively, 81.5% of Axsome Therapeutics shares are owned by institutional investors. 23.5% of Oruka Therapeutics shares are owned by insiders. Comparatively, 20.6% of Axsome Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

Oruka Therapeutics has a net margin of 0.00% compared to Axsome Therapeutics' net margin of -26.59%. Oruka Therapeutics' return on equity of -26.16% beat Axsome Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Oruka TherapeuticsN/A -26.16% -25.00%
Axsome Therapeutics -26.59%-267.16%-28.53%

Oruka Therapeutics currently has a consensus target price of $134.30, suggesting a potential upside of 45.72%. Axsome Therapeutics has a consensus target price of $261.48, suggesting a potential upside of 8.50%. Given Oruka Therapeutics' higher probable upside, research analysts clearly believe Oruka Therapeutics is more favorable than Axsome Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Oruka Therapeutics
1 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.82
Axsome Therapeutics
2 Sell rating(s)
0 Hold rating(s)
19 Buy rating(s)
2 Strong Buy rating(s)
2.91

In the previous week, Axsome Therapeutics had 8 more articles in the media than Oruka Therapeutics. MarketBeat recorded 13 mentions for Axsome Therapeutics and 5 mentions for Oruka Therapeutics. Oruka Therapeutics' average media sentiment score of 1.45 beat Axsome Therapeutics' score of 1.03 indicating that Oruka Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Oruka Therapeutics
4 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Axsome Therapeutics
7 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Oruka Therapeutics has higher earnings, but lower revenue than Axsome Therapeutics. Axsome Therapeutics is trading at a lower price-to-earnings ratio than Oruka Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Oruka TherapeuticsN/AN/A-$105.43M-$1.94N/A
Axsome Therapeutics$638.50M19.42-$183.17M-$3.73N/A

Summary

Oruka Therapeutics beats Axsome Therapeutics on 9 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding ORKA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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ORKA vs. The Competition

MetricOruka TherapeuticsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$5.55B$3.08B$6.88B$12.26B
Dividend YieldN/A2.07%2.67%9.79%
P/E Ratio-47.5020.2927.0023.71
Price / SalesN/A353.88492.7776.09
Price / CashN/A27.6250.5459.64
Price / Book9.514.1310.286.07
Net Income-$105.43M$65.94M$3.60B$331.84M
7 Day Performance-0.58%-4.18%-1.25%-1.53%
1 Month Performance6.38%-3.76%-0.35%-2.46%
1 Year Performance546.74%9.93%18.41%13.66%

Oruka Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
ORKA
Oruka Therapeutics
3.6307 of 5 stars
$92.16
+0.2%
$134.30
+45.7%
+547.6%$5.55BN/AN/AN/A
GMAB
Genmab A/S
4.793 of 5 stars
$28.72
-0.9%
$38.21
+33.1%
+22.2%$18.07B$3.72B21.763,029
ASND
Ascendis Pharma A/S
4.7289 of 5 stars
$261.00
+0.5%
$295.67
+13.3%
+50.8%$16.21B$865.78M30.101,189
BBIO
BridgeBio Pharma
2.982 of 5 stars
$81.38
+1.3%
$95.21
+17.0%
+84.0%$15.73B$502.08MN/A400
ELAN
Elanco Animal Health
3.7809 of 5 stars
$25.84
-0.4%
$28.55
+10.5%
+69.5%$12.96B$4.72BN/A9,400

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This page (NASDAQ:ORKA) was last updated on 7/25/2026 by MarketBeat.com Staff.
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