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Alnylam Pharmaceuticals (ALNY) Competitors

Alnylam Pharmaceuticals logo
$236.22 +6.92 (+3.02%)
As of 08/21/2026 04:00 PM Eastern

ALNY vs. REGN, ARGX, MRNA, NTRA, and RVMD

Should you buy Alnylam Pharmaceuticals stock or one of its competitors? Alnylam Pharmaceuticals's main competitors and comparable companies include Regeneron Pharmaceuticals (REGN), argenex (ARGX), Moderna (MRNA), Natera (NTRA), and Revolution Medicines (RVMD). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Alnylam Pharmaceuticals compare to Regeneron Pharmaceuticals?

Regeneron Pharmaceuticals (NASDAQ:REGN) and Alnylam Pharmaceuticals (NASDAQ:ALNY) are both large-cap healthcare companies, but which is the better stock? We will contrast the two businesses based on the strength of their dividends, media sentiment, valuation, risk, earnings, profitability, institutional ownership and analyst recommendations.

Regeneron Pharmaceuticals has higher revenue and earnings than Alnylam Pharmaceuticals. Regeneron Pharmaceuticals is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Regeneron Pharmaceuticals$14.34B5.99$4.50B$40.4620.61
Alnylam Pharmaceuticals$4.80B6.58$313.75M$5.3843.91

Regeneron Pharmaceuticals has a net margin of 27.86% compared to Alnylam Pharmaceuticals' net margin of 15.26%. Alnylam Pharmaceuticals' return on equity of 84.93% beat Regeneron Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Regeneron Pharmaceuticals27.86% 13.47% 10.34%
Alnylam Pharmaceuticals 15.26%84.93%14.30%

In the previous week, Regeneron Pharmaceuticals had 51 more articles in the media than Alnylam Pharmaceuticals. MarketBeat recorded 75 mentions for Regeneron Pharmaceuticals and 24 mentions for Alnylam Pharmaceuticals. Regeneron Pharmaceuticals' average media sentiment score of 0.89 beat Alnylam Pharmaceuticals' score of 0.81 indicating that Regeneron Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Regeneron Pharmaceuticals
47 Very Positive mention(s)
1 Positive mention(s)
24 Neutral mention(s)
0 Negative mention(s)
2 Very Negative mention(s)
Positive
Alnylam Pharmaceuticals
11 Very Positive mention(s)
1 Positive mention(s)
9 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Regeneron Pharmaceuticals presently has a consensus target price of $801.70, indicating a potential downside of 3.88%. Alnylam Pharmaceuticals has a consensus target price of $386.62, indicating a potential upside of 63.67%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher probable upside, analysts plainly believe Alnylam Pharmaceuticals is more favorable than Regeneron Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Regeneron Pharmaceuticals
0 Sell rating(s)
10 Hold rating(s)
16 Buy rating(s)
0 Strong Buy rating(s)
2.62
Alnylam Pharmaceuticals
0 Sell rating(s)
5 Hold rating(s)
15 Buy rating(s)
4 Strong Buy rating(s)
2.96

Regeneron Pharmaceuticals has a beta of 0.22, suggesting that its stock price is 78% less volatile than the broader market. Comparatively, Alnylam Pharmaceuticals has a beta of 0.3, suggesting that its stock price is 70% less volatile than the broader market.

83.3% of Regeneron Pharmaceuticals shares are owned by institutional investors. Comparatively, 93.0% of Alnylam Pharmaceuticals shares are owned by institutional investors. 7.0% of Regeneron Pharmaceuticals shares are owned by company insiders. Comparatively, 0.9% of Alnylam Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

Summary

Alnylam Pharmaceuticals beats Regeneron Pharmaceuticals on 9 of the 17 factors compared between the two stocks.

How does Alnylam Pharmaceuticals compare to argenex?

Alnylam Pharmaceuticals (NASDAQ:ALNY) and argenex (NASDAQ:ARGX) are both large-cap healthcare companies, but which is the better stock? We will contrast the two businesses based on the strength of their media sentiment, analyst recommendations, earnings, dividends, profitability, institutional ownership, risk and valuation.

Alnylam Pharmaceuticals has a beta of 0.3, indicating that its stock price is 70% less volatile than the broader market. Comparatively, argenex has a beta of 0.46, indicating that its stock price is 54% less volatile than the broader market.

argenex has lower revenue, but higher earnings than Alnylam Pharmaceuticals. argenex is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alnylam Pharmaceuticals$4.80B6.58$313.75M$5.3843.91
argenex$4.25B15.31$1.29B$26.0439.93

In the previous week, argenex had 18 more articles in the media than Alnylam Pharmaceuticals. MarketBeat recorded 42 mentions for argenex and 24 mentions for Alnylam Pharmaceuticals. Alnylam Pharmaceuticals' average media sentiment score of 0.81 beat argenex's score of 0.81 indicating that Alnylam Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Alnylam Pharmaceuticals
11 Very Positive mention(s)
1 Positive mention(s)
9 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
argenex
13 Very Positive mention(s)
9 Positive mention(s)
9 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

argenex has a net margin of 32.19% compared to Alnylam Pharmaceuticals' net margin of 15.26%. Alnylam Pharmaceuticals' return on equity of 84.93% beat argenex's return on equity.

Company Net Margins Return on Equity Return on Assets
Alnylam Pharmaceuticals15.26% 84.93% 14.30%
argenex 32.19%43.59%36.66%

Alnylam Pharmaceuticals presently has a consensus price target of $386.62, indicating a potential upside of 63.67%. argenex has a consensus price target of $1,118.28, indicating a potential upside of 7.55%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher possible upside, analysts plainly believe Alnylam Pharmaceuticals is more favorable than argenex.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alnylam Pharmaceuticals
0 Sell rating(s)
5 Hold rating(s)
15 Buy rating(s)
4 Strong Buy rating(s)
2.96
argenex
0 Sell rating(s)
4 Hold rating(s)
18 Buy rating(s)
2 Strong Buy rating(s)
2.92

93.0% of Alnylam Pharmaceuticals shares are held by institutional investors. Comparatively, 60.3% of argenex shares are held by institutional investors. 0.9% of Alnylam Pharmaceuticals shares are held by company insiders. Comparatively, 2.4% of argenex shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company is poised for long-term growth.

Summary

argenex beats Alnylam Pharmaceuticals on 9 of the 17 factors compared between the two stocks.

How does Alnylam Pharmaceuticals compare to Moderna?

Alnylam Pharmaceuticals (NASDAQ:ALNY) and Moderna (NASDAQ:MRNA) are both large-cap healthcare companies, but which is the superior stock? We will contrast the two businesses based on the strength of their profitability, institutional ownership, risk, valuation, analyst recommendations, media sentiment, dividends and earnings.

Alnylam Pharmaceuticals currently has a consensus target price of $386.62, suggesting a potential upside of 63.67%. Moderna has a consensus target price of $69.50, suggesting a potential downside of 52.09%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher possible upside, equities analysts plainly believe Alnylam Pharmaceuticals is more favorable than Moderna.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alnylam Pharmaceuticals
0 Sell rating(s)
5 Hold rating(s)
15 Buy rating(s)
4 Strong Buy rating(s)
2.96
Moderna
4 Sell rating(s)
11 Hold rating(s)
4 Buy rating(s)
0 Strong Buy rating(s)
2.00

In the previous week, Moderna had 90 more articles in the media than Alnylam Pharmaceuticals. MarketBeat recorded 114 mentions for Moderna and 24 mentions for Alnylam Pharmaceuticals. Alnylam Pharmaceuticals' average media sentiment score of 0.81 beat Moderna's score of 0.38 indicating that Alnylam Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Alnylam Pharmaceuticals
11 Very Positive mention(s)
1 Positive mention(s)
9 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Moderna
45 Very Positive mention(s)
18 Positive mention(s)
14 Neutral mention(s)
18 Negative mention(s)
14 Very Negative mention(s)
Neutral

Alnylam Pharmaceuticals has a net margin of 15.26% compared to Moderna's net margin of -141.43%. Alnylam Pharmaceuticals' return on equity of 84.93% beat Moderna's return on equity.

Company Net Margins Return on Equity Return on Assets
Alnylam Pharmaceuticals15.26% 84.93% 14.30%
Moderna -141.43%-28.30%-19.39%

Alnylam Pharmaceuticals has a beta of 0.3, meaning that its stock price is 70% less volatile than the broader market. Comparatively, Moderna has a beta of 0.91, meaning that its stock price is 9% less volatile than the broader market.

93.0% of Alnylam Pharmaceuticals shares are held by institutional investors. Comparatively, 75.3% of Moderna shares are held by institutional investors. 0.9% of Alnylam Pharmaceuticals shares are held by insiders. Comparatively, 10.8% of Moderna shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

Alnylam Pharmaceuticals has higher revenue and earnings than Moderna. Moderna is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alnylam Pharmaceuticals$4.80B6.58$313.75M$5.3843.91
Moderna$1.94B29.79-$2.82B-$7.99N/A

Summary

Alnylam Pharmaceuticals beats Moderna on 13 of the 17 factors compared between the two stocks.

How does Alnylam Pharmaceuticals compare to Natera?

Alnylam Pharmaceuticals (NASDAQ:ALNY) and Natera (NASDAQ:NTRA) are both large-cap healthcare companies, but which is the better business? We will contrast the two companies based on the strength of their media sentiment, dividends, analyst recommendations, earnings, institutional ownership, profitability, valuation and risk.

93.0% of Alnylam Pharmaceuticals shares are held by institutional investors. Comparatively, 99.9% of Natera shares are held by institutional investors. 0.9% of Alnylam Pharmaceuticals shares are held by insiders. Comparatively, 5.1% of Natera shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

In the previous week, Natera had 7 more articles in the media than Alnylam Pharmaceuticals. MarketBeat recorded 31 mentions for Natera and 24 mentions for Alnylam Pharmaceuticals. Natera's average media sentiment score of 1.34 beat Alnylam Pharmaceuticals' score of 0.81 indicating that Natera is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Alnylam Pharmaceuticals
11 Very Positive mention(s)
1 Positive mention(s)
9 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Natera
25 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
1 Very Negative mention(s)
Positive

Alnylam Pharmaceuticals has a net margin of 15.26% compared to Natera's net margin of -7.11%. Alnylam Pharmaceuticals' return on equity of 84.93% beat Natera's return on equity.

Company Net Margins Return on Equity Return on Assets
Alnylam Pharmaceuticals15.26% 84.93% 14.30%
Natera -7.11%-11.38%-7.87%

Alnylam Pharmaceuticals has higher revenue and earnings than Natera. Natera is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alnylam Pharmaceuticals$4.80B6.58$313.75M$5.3843.91
Natera$2.31B20.75-$208.16M-$1.36N/A

Alnylam Pharmaceuticals has a beta of 0.3, indicating that its stock price is 70% less volatile than the broader market. Comparatively, Natera has a beta of 1.51, indicating that its stock price is 51% more volatile than the broader market.

Alnylam Pharmaceuticals currently has a consensus target price of $386.62, suggesting a potential upside of 63.67%. Natera has a consensus target price of $319.38, suggesting a potential downside of 3.81%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher probable upside, equities research analysts clearly believe Alnylam Pharmaceuticals is more favorable than Natera.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alnylam Pharmaceuticals
0 Sell rating(s)
5 Hold rating(s)
15 Buy rating(s)
4 Strong Buy rating(s)
2.96
Natera
1 Sell rating(s)
4 Hold rating(s)
15 Buy rating(s)
2 Strong Buy rating(s)
2.82

Summary

Alnylam Pharmaceuticals beats Natera on 10 of the 16 factors compared between the two stocks.

How does Alnylam Pharmaceuticals compare to Revolution Medicines?

Revolution Medicines (NASDAQ:RVMD) and Alnylam Pharmaceuticals (NASDAQ:ALNY) are both large-cap healthcare companies, but which is the better business? We will compare the two companies based on the strength of their valuation, institutional ownership, analyst recommendations, dividends, earnings, profitability, risk and media sentiment.

94.3% of Revolution Medicines shares are held by institutional investors. Comparatively, 93.0% of Alnylam Pharmaceuticals shares are held by institutional investors. 7.6% of Revolution Medicines shares are held by company insiders. Comparatively, 0.9% of Alnylam Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Revolution Medicines currently has a consensus price target of $167.89, suggesting a potential downside of 19.85%. Alnylam Pharmaceuticals has a consensus price target of $386.62, suggesting a potential upside of 63.67%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher possible upside, analysts plainly believe Alnylam Pharmaceuticals is more favorable than Revolution Medicines.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Revolution Medicines
1 Sell rating(s)
1 Hold rating(s)
18 Buy rating(s)
1 Strong Buy rating(s)
2.90
Alnylam Pharmaceuticals
0 Sell rating(s)
5 Hold rating(s)
15 Buy rating(s)
4 Strong Buy rating(s)
2.96

In the previous week, Alnylam Pharmaceuticals had 12 more articles in the media than Revolution Medicines. MarketBeat recorded 24 mentions for Alnylam Pharmaceuticals and 12 mentions for Revolution Medicines. Revolution Medicines' average media sentiment score of 1.37 beat Alnylam Pharmaceuticals' score of 0.81 indicating that Revolution Medicines is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Revolution Medicines
10 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Positive
Alnylam Pharmaceuticals
11 Very Positive mention(s)
1 Positive mention(s)
9 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Alnylam Pharmaceuticals has a net margin of 15.26% compared to Revolution Medicines' net margin of 0.00%. Alnylam Pharmaceuticals' return on equity of 84.93% beat Revolution Medicines' return on equity.

Company Net Margins Return on Equity Return on Assets
Revolution MedicinesN/A -88.20% -57.85%
Alnylam Pharmaceuticals 15.26%84.93%14.30%

Alnylam Pharmaceuticals has higher revenue and earnings than Revolution Medicines. Revolution Medicines is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Revolution Medicines$11.58M3,877.00-$1.13B-$8.82N/A
Alnylam Pharmaceuticals$4.80B6.58$313.75M$5.3843.91

Revolution Medicines has a beta of 1.39, meaning that its stock price is 39% more volatile than the broader market. Comparatively, Alnylam Pharmaceuticals has a beta of 0.3, meaning that its stock price is 70% less volatile than the broader market.

Summary

Alnylam Pharmaceuticals beats Revolution Medicines on 11 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding ALNY and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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ALNY vs. The Competition

MetricAlnylam PharmaceuticalsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$31.61B$4.01B$7.37B$12.85B
Dividend YieldN/A3.64%2.53%11.08%
P/E Ratio43.9111.62272.8824.24
Price / Sales6.581,338.17618.9699.81
Price / Cash84.48105.1478.6253.99
Price / Book23.3416.8013.056.20
Net Income$313.75M-$12.50M$3.47B$348.59M
7 Day Performance3.31%3.29%2.09%0.08%
1 Month Performance-12.10%8.23%6.64%3.88%
1 Year Performance-48.01%55.05%25.02%16.98%

Alnylam Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
ALNY
Alnylam Pharmaceuticals
4.9376 of 5 stars
$236.22
+3.0%
$386.62
+63.7%
-48.0%$31.61B$4.80B43.912,770
REGN
Regeneron Pharmaceuticals
4.0826 of 5 stars
$837.60
+1.3%
$801.70
-4.3%
+41.5%$86.24B$14.34B20.7015,410
ARGX
argenex
4.2633 of 5 stars
$1,051.33
+1.3%
$1,118.28
+6.4%
+57.5%$65.77B$4.25B40.371,863
MRNA
Moderna
1.6445 of 5 stars
$146.10
+9.6%
$69.50
-52.4%
+434.9%$58.33B$2.21BN/A4,700
NTRA
Natera
2.5992 of 5 stars
$328.89
+1.2%
$319.38
-2.9%
+100.5%$47.41B$2.31BN/A6,140

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This page (NASDAQ:ALNY) was last updated on 8/23/2026 by MarketBeat.com Staff.
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