Alnylam Pharmaceuticals (ALNY) Competitors $314.94 -7.70 (-2.39%) Closing price 07/11/2025 04:00 PM EasternExtended Trading$314.32 -0.63 (-0.20%) As of 07/11/2025 07:47 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock ALNY vs. AMGN, GILD, VRTX, REGN, BIIB, UTHR, INCY, NBIX, EXEL, and BMRNShould you be buying Alnylam Pharmaceuticals stock or one of its competitors? The main competitors of Alnylam Pharmaceuticals include Amgen (AMGN), Gilead Sciences (GILD), Vertex Pharmaceuticals (VRTX), Regeneron Pharmaceuticals (REGN), Biogen (BIIB), United Therapeutics (UTHR), Incyte (INCY), Neurocrine Biosciences (NBIX), Exelixis (EXEL), and BioMarin Pharmaceutical (BMRN). These companies are all part of the "biotechnology" industry. Alnylam Pharmaceuticals vs. Its Competitors Amgen Gilead Sciences Vertex Pharmaceuticals Regeneron Pharmaceuticals Biogen United Therapeutics Incyte Neurocrine Biosciences Exelixis BioMarin Pharmaceutical Amgen (NASDAQ:AMGN) and Alnylam Pharmaceuticals (NASDAQ:ALNY) are both large-cap medical companies, but which is the superior investment? We will contrast the two businesses based on the strength of their media sentiment, institutional ownership, risk, dividends, analyst recommendations, profitability, earnings and valuation. Does the media favor AMGN or ALNY? In the previous week, Amgen had 30 more articles in the media than Alnylam Pharmaceuticals. MarketBeat recorded 50 mentions for Amgen and 20 mentions for Alnylam Pharmaceuticals. Amgen's average media sentiment score of 1.52 beat Alnylam Pharmaceuticals' score of 1.14 indicating that Amgen is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Amgen 45 Very Positive mention(s) 1 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Very Positive Alnylam Pharmaceuticals 11 Very Positive mention(s) 0 Positive mention(s) 5 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Which has more risk & volatility, AMGN or ALNY? Amgen has a beta of 0.49, meaning that its share price is 51% less volatile than the S&P 500. Comparatively, Alnylam Pharmaceuticals has a beta of 0.23, meaning that its share price is 77% less volatile than the S&P 500. Do institutionals and insiders believe in AMGN or ALNY? 76.5% of Amgen shares are owned by institutional investors. Comparatively, 93.0% of Alnylam Pharmaceuticals shares are owned by institutional investors. 0.8% of Amgen shares are owned by company insiders. Comparatively, 1.5% of Alnylam Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth. Which has higher earnings and valuation, AMGN or ALNY? Amgen has higher revenue and earnings than Alnylam Pharmaceuticals. Alnylam Pharmaceuticals is trading at a lower price-to-earnings ratio than Amgen, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioAmgen$34.13B4.65$4.09B$10.9626.94Alnylam Pharmaceuticals$2.35B17.49-$278.16M-$2.09-150.69 Do analysts rate AMGN or ALNY? Amgen presently has a consensus target price of $307.82, indicating a potential upside of 4.25%. Alnylam Pharmaceuticals has a consensus target price of $345.70, indicating a potential upside of 9.77%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher probable upside, analysts plainly believe Alnylam Pharmaceuticals is more favorable than Amgen.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Amgen 2 Sell rating(s) 12 Hold rating(s) 8 Buy rating(s) 1 Strong Buy rating(s) 2.35Alnylam Pharmaceuticals 1 Sell rating(s) 3 Hold rating(s) 21 Buy rating(s) 0 Strong Buy rating(s) 2.80 Is AMGN or ALNY more profitable? Amgen has a net margin of 17.39% compared to Alnylam Pharmaceuticals' net margin of -11.49%. Amgen's return on equity of 176.11% beat Alnylam Pharmaceuticals' return on equity.Company Net Margins Return on Equity Return on Assets Amgen17.39% 176.11% 12.39% Alnylam Pharmaceuticals -11.49%-510.31%-6.48% SummaryAmgen beats Alnylam Pharmaceuticals on 11 of the 17 factors compared between the two stocks. Get Alnylam Pharmaceuticals News Delivered to You Automatically Sign up to receive the latest news and ratings for ALNY and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding ALNY and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart ALNY vs. The Competition Export to ExcelMetricAlnylam PharmaceuticalsMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$41.06B$2.96B$5.61B$9.10BDividend YieldN/A2.39%5.24%4.00%P/E Ratio-150.6920.8528.1820.27Price / Sales17.49289.80428.6998.03Price / CashN/A42.8637.4658.16Price / Book605.657.638.045.49Net Income-$278.16M-$55.05M$3.19B$250.45M7 Day Performance-5.12%8.43%3.62%4.79%1 Month Performance3.37%5.42%4.06%7.68%1 Year Performance20.89%2.03%30.00%16.43% Alnylam Pharmaceuticals Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)ALNYAlnylam Pharmaceuticals4.1806 of 5 stars$314.94-2.4%$345.70+9.8%+20.7%$41.06B$2.35B-150.692,230Positive NewsAnalyst ForecastAMGNAmgen4.4341 of 5 stars$292.95-1.8%$307.82+5.1%-9.2%$157.52B$33.42B26.7328,000Positive NewsAnalyst RevisionGILDGilead Sciences4.9342 of 5 stars$111.78+0.0%$110.55-1.1%+56.7%$139.05B$28.75B23.5317,600Positive NewsAnalyst RevisionVRTXVertex Pharmaceuticals4.3242 of 5 stars$459.410.0%$511.62+11.4%-4.7%$117.98B$11.10B-117.206,100Positive NewsAnalyst RevisionREGNRegeneron Pharmaceuticals4.8318 of 5 stars$538.11-1.7%$813.57+51.2%-47.4%$58.09B$14.20B13.7015,106Trending NewsAnalyst ForecastAnalyst RevisionBIIBBiogen4.7787 of 5 stars$130.13-2.1%$188.48+44.8%-43.3%$19.07B$9.68B12.857,605Trending NewsAnalyst RevisionUTHRUnited Therapeutics4.9895 of 5 stars$290.39-1.4%$386.15+33.0%-8.8%$13.10B$2.88B11.591,305Analyst ForecastINCYIncyte4.7302 of 5 stars$67.27-1.7%$74.53+10.8%+10.1%$13.02B$4.24B210.232,617NBIXNeurocrine Biosciences4.4743 of 5 stars$127.88-1.0%$162.00+26.7%-8.9%$12.66B$2.36B43.351,800Trending NewsAnalyst ForecastInsider TradeAnalyst RevisionEXELExelixis4.79 of 5 stars$44.16-4.3%$43.56-1.4%+98.9%$12.04B$2.17B20.071,147Analyst ForecastBMRNBioMarin Pharmaceutical4.9484 of 5 stars$57.41-0.2%$93.61+63.1%-30.8%$11.01B$2.85B21.343,040News CoveragePositive News Related Companies and Tools Related Companies Amgen Alternatives Gilead Sciences Alternatives Vertex Pharmaceuticals Alternatives Regeneron Pharmaceuticals Alternatives Biogen Alternatives United Therapeutics Alternatives Incyte Alternatives Neurocrine Biosciences Alternatives Exelixis Alternatives BioMarin Pharmaceutical Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:ALNY) was last updated on 7/12/2025 by MarketBeat.com Staff From Our PartnersThis Signal Only Flashes Once Every 4 Years – And It Just TriggeredThis same signal has appeared twice before in the past 8 years — both times, it kicked off major moves in cryp...Crypto Swap Profits | SponsoredI was wrong about TrumpI made a mistake. 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