Alnylam Pharmaceuticals (ALNY) Competitors

Alnylam Pharmaceuticals logo
$288.18 +1.77 (+0.62%)
Closing price 06/23/2026 04:00 PM Eastern
Extended Trading
$286.75 -1.43 (-0.50%)
As of 04:00 AM Eastern
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ALNY vs. VRTX, REGN, BIIB, UTHR, and INCY

Should you buy Alnylam Pharmaceuticals stock or one of its competitors? MarketBeat compares Alnylam Pharmaceuticals with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Alnylam Pharmaceuticals include Vertex Pharmaceuticals (VRTX), Regeneron Pharmaceuticals (REGN), Biogen (BIIB), United Therapeutics (UTHR), and Incyte (INCY). These companies are all part of the "biotechnology" industry.

How does Alnylam Pharmaceuticals compare to Vertex Pharmaceuticals?

Vertex Pharmaceuticals (NASDAQ:VRTX) and Alnylam Pharmaceuticals (NASDAQ:ALNY) are both large-cap medical companies, but which is the superior business? We will contrast the two businesses based on the strength of their earnings, analyst recommendations, dividends, valuation, risk, profitability, institutional ownership and media sentiment.

Vertex Pharmaceuticals has a net margin of 35.51% compared to Alnylam Pharmaceuticals' net margin of 11.72%. Alnylam Pharmaceuticals' return on equity of 85.76% beat Vertex Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Vertex Pharmaceuticals35.51% 23.86% 17.13%
Alnylam Pharmaceuticals 11.72%85.76%10.32%

91.0% of Vertex Pharmaceuticals shares are owned by institutional investors. Comparatively, 93.0% of Alnylam Pharmaceuticals shares are owned by institutional investors. 0.2% of Vertex Pharmaceuticals shares are owned by insiders. Comparatively, 0.9% of Alnylam Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

Vertex Pharmaceuticals has a beta of 0.3, meaning that its stock price is 70% less volatile than the broader market. Comparatively, Alnylam Pharmaceuticals has a beta of 0.29, meaning that its stock price is 71% less volatile than the broader market.

Vertex Pharmaceuticals currently has a consensus target price of $555.91, indicating a potential upside of 18.68%. Alnylam Pharmaceuticals has a consensus target price of $463.13, indicating a potential upside of 60.71%. Given Alnylam Pharmaceuticals' higher probable upside, analysts plainly believe Alnylam Pharmaceuticals is more favorable than Vertex Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Vertex Pharmaceuticals
0 Sell rating(s)
3 Hold rating(s)
22 Buy rating(s)
0 Strong Buy rating(s)
2.88
Alnylam Pharmaceuticals
0 Sell rating(s)
6 Hold rating(s)
18 Buy rating(s)
2 Strong Buy rating(s)
2.85

Vertex Pharmaceuticals has higher revenue and earnings than Alnylam Pharmaceuticals. Vertex Pharmaceuticals is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Vertex Pharmaceuticals$12.22B9.73$3.95B$16.8627.78
Alnylam Pharmaceuticals$3.71B10.36$313.75M$3.6678.74

In the previous week, Vertex Pharmaceuticals had 19 more articles in the media than Alnylam Pharmaceuticals. MarketBeat recorded 37 mentions for Vertex Pharmaceuticals and 18 mentions for Alnylam Pharmaceuticals. Vertex Pharmaceuticals' average media sentiment score of 1.06 beat Alnylam Pharmaceuticals' score of 0.82 indicating that Vertex Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Vertex Pharmaceuticals
25 Very Positive mention(s)
4 Positive mention(s)
5 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Alnylam Pharmaceuticals
11 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
3 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Vertex Pharmaceuticals beats Alnylam Pharmaceuticals on 10 of the 17 factors compared between the two stocks.

How does Alnylam Pharmaceuticals compare to Regeneron Pharmaceuticals?

Alnylam Pharmaceuticals (NASDAQ:ALNY) and Regeneron Pharmaceuticals (NASDAQ:REGN) are both large-cap medical companies, but which is the better business? We will contrast the two companies based on the strength of their valuation, risk, dividends, analyst recommendations, profitability, institutional ownership, media sentiment and earnings.

Regeneron Pharmaceuticals has higher revenue and earnings than Alnylam Pharmaceuticals. Regeneron Pharmaceuticals is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alnylam Pharmaceuticals$3.71B10.36$313.75M$3.6678.74
Regeneron Pharmaceuticals$14.34B4.56$4.50B$41.0415.06

Alnylam Pharmaceuticals has a beta of 0.29, suggesting that its stock price is 71% less volatile than the broader market. Comparatively, Regeneron Pharmaceuticals has a beta of 0.25, suggesting that its stock price is 75% less volatile than the broader market.

In the previous week, Regeneron Pharmaceuticals had 11 more articles in the media than Alnylam Pharmaceuticals. MarketBeat recorded 29 mentions for Regeneron Pharmaceuticals and 18 mentions for Alnylam Pharmaceuticals. Regeneron Pharmaceuticals' average media sentiment score of 1.48 beat Alnylam Pharmaceuticals' score of 0.82 indicating that Regeneron Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Alnylam Pharmaceuticals
11 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
3 Negative mention(s)
0 Very Negative mention(s)
Positive
Regeneron Pharmaceuticals
25 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

93.0% of Alnylam Pharmaceuticals shares are held by institutional investors. Comparatively, 83.3% of Regeneron Pharmaceuticals shares are held by institutional investors. 0.9% of Alnylam Pharmaceuticals shares are held by insiders. Comparatively, 7.0% of Regeneron Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Alnylam Pharmaceuticals currently has a consensus target price of $463.13, indicating a potential upside of 60.71%. Regeneron Pharmaceuticals has a consensus target price of $792.65, indicating a potential upside of 28.25%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher possible upside, analysts clearly believe Alnylam Pharmaceuticals is more favorable than Regeneron Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alnylam Pharmaceuticals
0 Sell rating(s)
6 Hold rating(s)
18 Buy rating(s)
2 Strong Buy rating(s)
2.85
Regeneron Pharmaceuticals
0 Sell rating(s)
10 Hold rating(s)
15 Buy rating(s)
2 Strong Buy rating(s)
2.70

Regeneron Pharmaceuticals has a net margin of 29.65% compared to Alnylam Pharmaceuticals' net margin of 11.72%. Alnylam Pharmaceuticals' return on equity of 85.76% beat Regeneron Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Alnylam Pharmaceuticals11.72% 85.76% 10.32%
Regeneron Pharmaceuticals 29.65%13.16%10.17%

Summary

Alnylam Pharmaceuticals beats Regeneron Pharmaceuticals on 9 of the 16 factors compared between the two stocks.

How does Alnylam Pharmaceuticals compare to Biogen?

Biogen (NASDAQ:BIIB) and Alnylam Pharmaceuticals (NASDAQ:ALNY) are both large-cap medical companies, but which is the superior investment? We will contrast the two companies based on the strength of their media sentiment, profitability, dividends, risk, earnings, institutional ownership, analyst recommendations and valuation.

Biogen has a net margin of 13.81% compared to Alnylam Pharmaceuticals' net margin of 11.72%. Alnylam Pharmaceuticals' return on equity of 85.76% beat Biogen's return on equity.

Company Net Margins Return on Equity Return on Assets
Biogen13.81% 12.83% 8.01%
Alnylam Pharmaceuticals 11.72%85.76%10.32%

Biogen currently has a consensus target price of $217.37, indicating a potential upside of 10.23%. Alnylam Pharmaceuticals has a consensus target price of $463.13, indicating a potential upside of 60.71%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher probable upside, analysts clearly believe Alnylam Pharmaceuticals is more favorable than Biogen.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Biogen
1 Sell rating(s)
12 Hold rating(s)
16 Buy rating(s)
1 Strong Buy rating(s)
2.57
Alnylam Pharmaceuticals
0 Sell rating(s)
6 Hold rating(s)
18 Buy rating(s)
2 Strong Buy rating(s)
2.85

87.9% of Biogen shares are owned by institutional investors. Comparatively, 93.0% of Alnylam Pharmaceuticals shares are owned by institutional investors. 0.3% of Biogen shares are owned by insiders. Comparatively, 0.9% of Alnylam Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

Biogen has a beta of 0.2, indicating that its stock price is 80% less volatile than the broader market. Comparatively, Alnylam Pharmaceuticals has a beta of 0.29, indicating that its stock price is 71% less volatile than the broader market.

Biogen has higher revenue and earnings than Alnylam Pharmaceuticals. Biogen is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Biogen$9.89B2.94$1.29B$9.3221.16
Alnylam Pharmaceuticals$3.71B10.36$313.75M$3.6678.74

In the previous week, Biogen had 8 more articles in the media than Alnylam Pharmaceuticals. MarketBeat recorded 26 mentions for Biogen and 18 mentions for Alnylam Pharmaceuticals. Biogen's average media sentiment score of 0.90 beat Alnylam Pharmaceuticals' score of 0.82 indicating that Biogen is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Biogen
14 Very Positive mention(s)
5 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Alnylam Pharmaceuticals
11 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
3 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Alnylam Pharmaceuticals beats Biogen on 11 of the 17 factors compared between the two stocks.

How does Alnylam Pharmaceuticals compare to United Therapeutics?

United Therapeutics (NASDAQ:UTHR) and Alnylam Pharmaceuticals (NASDAQ:ALNY) are both large-cap medical companies, but which is the superior business? We will contrast the two businesses based on the strength of their earnings, valuation, profitability, analyst recommendations, dividends, media sentiment, institutional ownership and risk.

United Therapeutics currently has a consensus target price of $619.42, suggesting a potential upside of 13.79%. Alnylam Pharmaceuticals has a consensus target price of $463.13, suggesting a potential upside of 60.71%. Given Alnylam Pharmaceuticals' higher probable upside, analysts clearly believe Alnylam Pharmaceuticals is more favorable than United Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
United Therapeutics
0 Sell rating(s)
2 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.85
Alnylam Pharmaceuticals
0 Sell rating(s)
6 Hold rating(s)
18 Buy rating(s)
2 Strong Buy rating(s)
2.85

United Therapeutics has a net margin of 40.62% compared to Alnylam Pharmaceuticals' net margin of 11.72%. Alnylam Pharmaceuticals' return on equity of 85.76% beat United Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
United Therapeutics40.62% 19.24% 17.25%
Alnylam Pharmaceuticals 11.72%85.76%10.32%

94.1% of United Therapeutics shares are owned by institutional investors. Comparatively, 93.0% of Alnylam Pharmaceuticals shares are owned by institutional investors. 8.6% of United Therapeutics shares are owned by insiders. Comparatively, 0.9% of Alnylam Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.

United Therapeutics has higher earnings, but lower revenue than Alnylam Pharmaceuticals. United Therapeutics is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
United Therapeutics$3.18B7.26$1.33B$27.0920.09
Alnylam Pharmaceuticals$3.71B10.36$313.75M$3.6678.74

United Therapeutics has a beta of 0.57, suggesting that its stock price is 43% less volatile than the broader market. Comparatively, Alnylam Pharmaceuticals has a beta of 0.29, suggesting that its stock price is 71% less volatile than the broader market.

In the previous week, United Therapeutics had 1 more articles in the media than Alnylam Pharmaceuticals. MarketBeat recorded 19 mentions for United Therapeutics and 18 mentions for Alnylam Pharmaceuticals. United Therapeutics' average media sentiment score of 0.85 beat Alnylam Pharmaceuticals' score of 0.82 indicating that United Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
United Therapeutics
13 Very Positive mention(s)
2 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Alnylam Pharmaceuticals
11 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
3 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

United Therapeutics beats Alnylam Pharmaceuticals on 9 of the 16 factors compared between the two stocks.

How does Alnylam Pharmaceuticals compare to Incyte?

Incyte (NASDAQ:INCY) and Alnylam Pharmaceuticals (NASDAQ:ALNY) are both large-cap medical companies, but which is the superior business? We will contrast the two companies based on the strength of their profitability, earnings, analyst recommendations, media sentiment, institutional ownership, dividends, valuation and risk.

97.0% of Incyte shares are owned by institutional investors. Comparatively, 93.0% of Alnylam Pharmaceuticals shares are owned by institutional investors. 16.2% of Incyte shares are owned by insiders. Comparatively, 0.9% of Alnylam Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

In the previous week, Alnylam Pharmaceuticals had 7 more articles in the media than Incyte. MarketBeat recorded 18 mentions for Alnylam Pharmaceuticals and 11 mentions for Incyte. Incyte's average media sentiment score of 1.01 beat Alnylam Pharmaceuticals' score of 0.82 indicating that Incyte is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Incyte
6 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Alnylam Pharmaceuticals
11 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
3 Negative mention(s)
0 Very Negative mention(s)
Positive

Incyte has a beta of 0.79, suggesting that its share price is 21% less volatile than the broader market. Comparatively, Alnylam Pharmaceuticals has a beta of 0.29, suggesting that its share price is 71% less volatile than the broader market.

Incyte presently has a consensus target price of $106.90, suggesting a potential upside of 2.39%. Alnylam Pharmaceuticals has a consensus target price of $463.13, suggesting a potential upside of 60.71%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher probable upside, analysts plainly believe Alnylam Pharmaceuticals is more favorable than Incyte.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Incyte
0 Sell rating(s)
14 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.36
Alnylam Pharmaceuticals
0 Sell rating(s)
6 Hold rating(s)
18 Buy rating(s)
2 Strong Buy rating(s)
2.85

Incyte has a net margin of 26.71% compared to Alnylam Pharmaceuticals' net margin of 11.72%. Alnylam Pharmaceuticals' return on equity of 85.76% beat Incyte's return on equity.

Company Net Margins Return on Equity Return on Assets
Incyte26.71% 26.66% 19.77%
Alnylam Pharmaceuticals 11.72%85.76%10.32%

Incyte has higher revenue and earnings than Alnylam Pharmaceuticals. Incyte is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Incyte$5.14B4.06$1.29B$7.0814.75
Alnylam Pharmaceuticals$3.71B10.36$313.75M$3.6678.74

Summary

Incyte beats Alnylam Pharmaceuticals on 9 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding ALNY and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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ALNY vs. The Competition

MetricAlnylam PharmaceuticalsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$38.24B$3.45B$6.44B$12.38B
Dividend YieldN/A2.30%2.69%5.83%
P/E Ratio78.7419.7524.6723.99
Price / Sales10.36330.65528.41106.93
Price / Cash102.43128.5644.8254.51
Price / Book48.278.2910.766.50
Net Income$313.75M$23.85M$3.56B$336.88M
7 Day Performance1.93%2.87%1.03%-0.14%
1 Month Performance-3.12%2.19%0.45%0.77%
1 Year Performance-11.33%55.48%29.69%28.49%

Alnylam Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
ALNY
Alnylam Pharmaceuticals
4.4014 of 5 stars
$288.18
+0.6%
$463.13
+60.7%
-8.0%$38.24B$3.71B78.742,770
VRTX
Vertex Pharmaceuticals
4.2887 of 5 stars
$450.46
+1.2%
$555.91
+23.4%
+5.6%$112.92B$12.00B26.726,400
REGN
Regeneron Pharmaceuticals
4.888 of 5 stars
$614.98
+0.5%
$792.65
+28.9%
+20.7%$64.72B$14.34B14.9815,410
BIIB
Biogen
3.8978 of 5 stars
$198.64
-0.7%
$216.70
+9.1%
+58.1%$29.53B$9.89B21.317,500
UTHR
United Therapeutics
4.3555 of 5 stars
$549.57
+0.7%
$619.42
+12.7%
+90.1%$23.17B$3.18B20.291,400

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This page (NASDAQ:ALNY) was last updated on 6/24/2026 by MarketBeat.com Staff.
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