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Alnylam Pharmaceuticals (ALNY) Competitors

Alnylam Pharmaceuticals logo
$288.06 -10.70 (-3.58%)
Closing price 07/13/2026 04:00 PM Eastern
Extended Trading
$287.19 -0.87 (-0.30%)
As of 04:04 AM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

ALNY vs. GILD, VRTX, REGN, BIIB, and UTHR

Should you buy Alnylam Pharmaceuticals stock or one of its competitors? MarketBeat compares Alnylam Pharmaceuticals with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Alnylam Pharmaceuticals include Gilead Sciences (GILD), Vertex Pharmaceuticals (VRTX), Regeneron Pharmaceuticals (REGN), Biogen (BIIB), and United Therapeutics (UTHR). These companies are all part of the "biotechnology" industry.

How does Alnylam Pharmaceuticals compare to Gilead Sciences?

Alnylam Pharmaceuticals (NASDAQ:ALNY) and Gilead Sciences (NASDAQ:GILD) are both large-cap medical companies, but which is the better investment? We will compare the two companies based on the strength of their institutional ownership, valuation, risk, profitability, dividends, earnings, analyst recommendations and media sentiment.

Alnylam Pharmaceuticals has a beta of 0.27, meaning that its stock price is 73% less volatile than the broader market. Comparatively, Gilead Sciences has a beta of 0.32, meaning that its stock price is 68% less volatile than the broader market.

Gilead Sciences has higher revenue and earnings than Alnylam Pharmaceuticals. Gilead Sciences is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alnylam Pharmaceuticals$3.71B10.36$313.75M$3.6678.70
Gilead Sciences$29.44B5.54$8.51B$7.3417.90

93.0% of Alnylam Pharmaceuticals shares are owned by institutional investors. Comparatively, 83.7% of Gilead Sciences shares are owned by institutional investors. 0.9% of Alnylam Pharmaceuticals shares are owned by insiders. Comparatively, 0.3% of Gilead Sciences shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

In the previous week, Gilead Sciences had 12 more articles in the media than Alnylam Pharmaceuticals. MarketBeat recorded 36 mentions for Gilead Sciences and 24 mentions for Alnylam Pharmaceuticals. Gilead Sciences' average media sentiment score of 0.86 beat Alnylam Pharmaceuticals' score of 0.37 indicating that Gilead Sciences is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Alnylam Pharmaceuticals
6 Very Positive mention(s)
1 Positive mention(s)
9 Neutral mention(s)
4 Negative mention(s)
1 Very Negative mention(s)
Neutral
Gilead Sciences
22 Very Positive mention(s)
3 Positive mention(s)
2 Neutral mention(s)
5 Negative mention(s)
0 Very Negative mention(s)
Positive

Gilead Sciences has a net margin of 30.99% compared to Alnylam Pharmaceuticals' net margin of 11.72%. Alnylam Pharmaceuticals' return on equity of 85.76% beat Gilead Sciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Alnylam Pharmaceuticals11.72% 85.76% 10.32%
Gilead Sciences 30.99%48.19%18.28%

Alnylam Pharmaceuticals currently has a consensus target price of $457.57, indicating a potential upside of 58.84%. Gilead Sciences has a consensus target price of $159.04, indicating a potential upside of 21.03%. Given Alnylam Pharmaceuticals' higher probable upside, research analysts clearly believe Alnylam Pharmaceuticals is more favorable than Gilead Sciences.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alnylam Pharmaceuticals
0 Sell rating(s)
6 Hold rating(s)
18 Buy rating(s)
2 Strong Buy rating(s)
2.85
Gilead Sciences
0 Sell rating(s)
3 Hold rating(s)
26 Buy rating(s)
0 Strong Buy rating(s)
2.90

Summary

Gilead Sciences beats Alnylam Pharmaceuticals on 10 of the 17 factors compared between the two stocks.

How does Alnylam Pharmaceuticals compare to Vertex Pharmaceuticals?

Vertex Pharmaceuticals (NASDAQ:VRTX) and Alnylam Pharmaceuticals (NASDAQ:ALNY) are both large-cap medical companies, but which is the better business? We will contrast the two businesses based on the strength of their risk, valuation, profitability, earnings, analyst recommendations, media sentiment, institutional ownership and dividends.

91.0% of Vertex Pharmaceuticals shares are owned by institutional investors. Comparatively, 93.0% of Alnylam Pharmaceuticals shares are owned by institutional investors. 0.2% of Vertex Pharmaceuticals shares are owned by company insiders. Comparatively, 0.9% of Alnylam Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Vertex Pharmaceuticals has higher revenue and earnings than Alnylam Pharmaceuticals. Vertex Pharmaceuticals is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Vertex Pharmaceuticals$12.00B10.16$3.95B$16.8628.48
Alnylam Pharmaceuticals$3.71B10.36$313.75M$3.6678.70

In the previous week, Vertex Pharmaceuticals had 32 more articles in the media than Alnylam Pharmaceuticals. MarketBeat recorded 56 mentions for Vertex Pharmaceuticals and 24 mentions for Alnylam Pharmaceuticals. Vertex Pharmaceuticals' average media sentiment score of 0.80 beat Alnylam Pharmaceuticals' score of 0.37 indicating that Vertex Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Vertex Pharmaceuticals
31 Very Positive mention(s)
10 Positive mention(s)
12 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Alnylam Pharmaceuticals
6 Very Positive mention(s)
1 Positive mention(s)
9 Neutral mention(s)
4 Negative mention(s)
1 Very Negative mention(s)
Neutral

Vertex Pharmaceuticals has a net margin of 35.51% compared to Alnylam Pharmaceuticals' net margin of 11.72%. Alnylam Pharmaceuticals' return on equity of 85.76% beat Vertex Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Vertex Pharmaceuticals35.51% 23.86% 17.13%
Alnylam Pharmaceuticals 11.72%85.76%10.32%

Vertex Pharmaceuticals presently has a consensus price target of $559.61, suggesting a potential upside of 16.52%. Alnylam Pharmaceuticals has a consensus price target of $457.57, suggesting a potential upside of 58.84%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher probable upside, analysts plainly believe Alnylam Pharmaceuticals is more favorable than Vertex Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Vertex Pharmaceuticals
0 Sell rating(s)
4 Hold rating(s)
21 Buy rating(s)
0 Strong Buy rating(s)
2.84
Alnylam Pharmaceuticals
0 Sell rating(s)
6 Hold rating(s)
18 Buy rating(s)
2 Strong Buy rating(s)
2.85

Vertex Pharmaceuticals has a beta of 0.29, meaning that its stock price is 71% less volatile than the broader market. Comparatively, Alnylam Pharmaceuticals has a beta of 0.27, meaning that its stock price is 73% less volatile than the broader market.

Summary

Vertex Pharmaceuticals beats Alnylam Pharmaceuticals on 9 of the 17 factors compared between the two stocks.

How does Alnylam Pharmaceuticals compare to Regeneron Pharmaceuticals?

Regeneron Pharmaceuticals (NASDAQ:REGN) and Alnylam Pharmaceuticals (NASDAQ:ALNY) are both large-cap medical companies, but which is the superior business? We will contrast the two companies based on the strength of their risk, dividends, profitability, media sentiment, valuation, institutional ownership, earnings and analyst recommendations.

In the previous week, Regeneron Pharmaceuticals had 6 more articles in the media than Alnylam Pharmaceuticals. MarketBeat recorded 30 mentions for Regeneron Pharmaceuticals and 24 mentions for Alnylam Pharmaceuticals. Regeneron Pharmaceuticals' average media sentiment score of 0.44 beat Alnylam Pharmaceuticals' score of 0.37 indicating that Regeneron Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Regeneron Pharmaceuticals
11 Very Positive mention(s)
2 Positive mention(s)
5 Neutral mention(s)
5 Negative mention(s)
0 Very Negative mention(s)
Neutral
Alnylam Pharmaceuticals
6 Very Positive mention(s)
1 Positive mention(s)
9 Neutral mention(s)
4 Negative mention(s)
1 Very Negative mention(s)
Neutral

Regeneron Pharmaceuticals has a beta of 0.24, suggesting that its stock price is 76% less volatile than the broader market. Comparatively, Alnylam Pharmaceuticals has a beta of 0.27, suggesting that its stock price is 73% less volatile than the broader market.

Regeneron Pharmaceuticals has higher revenue and earnings than Alnylam Pharmaceuticals. Regeneron Pharmaceuticals is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Regeneron Pharmaceuticals$14.34B4.89$4.50B$41.0416.16
Alnylam Pharmaceuticals$3.71B10.36$313.75M$3.6678.70

83.3% of Regeneron Pharmaceuticals shares are owned by institutional investors. Comparatively, 93.0% of Alnylam Pharmaceuticals shares are owned by institutional investors. 7.0% of Regeneron Pharmaceuticals shares are owned by insiders. Comparatively, 0.9% of Alnylam Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Regeneron Pharmaceuticals has a net margin of 29.65% compared to Alnylam Pharmaceuticals' net margin of 11.72%. Alnylam Pharmaceuticals' return on equity of 85.76% beat Regeneron Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Regeneron Pharmaceuticals29.65% 13.16% 10.17%
Alnylam Pharmaceuticals 11.72%85.76%10.32%

Regeneron Pharmaceuticals currently has a consensus target price of $787.67, indicating a potential upside of 18.79%. Alnylam Pharmaceuticals has a consensus target price of $457.57, indicating a potential upside of 58.84%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher probable upside, analysts clearly believe Alnylam Pharmaceuticals is more favorable than Regeneron Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Regeneron Pharmaceuticals
0 Sell rating(s)
9 Hold rating(s)
17 Buy rating(s)
1 Strong Buy rating(s)
2.70
Alnylam Pharmaceuticals
0 Sell rating(s)
6 Hold rating(s)
18 Buy rating(s)
2 Strong Buy rating(s)
2.85

Summary

Alnylam Pharmaceuticals beats Regeneron Pharmaceuticals on 10 of the 17 factors compared between the two stocks.

How does Alnylam Pharmaceuticals compare to Biogen?

Biogen (NASDAQ:BIIB) and Alnylam Pharmaceuticals (NASDAQ:ALNY) are both large-cap medical companies, but which is the better stock? We will compare the two companies based on the strength of their profitability, media sentiment, dividends, valuation, risk, institutional ownership, analyst recommendations and earnings.

Biogen has higher revenue and earnings than Alnylam Pharmaceuticals. Biogen is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Biogen$9.89B3.12$1.29B$9.3222.43
Alnylam Pharmaceuticals$3.71B10.36$313.75M$3.6678.70

In the previous week, Biogen had 9 more articles in the media than Alnylam Pharmaceuticals. MarketBeat recorded 33 mentions for Biogen and 24 mentions for Alnylam Pharmaceuticals. Biogen's average media sentiment score of 0.93 beat Alnylam Pharmaceuticals' score of 0.37 indicating that Biogen is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Biogen
18 Very Positive mention(s)
4 Positive mention(s)
6 Neutral mention(s)
3 Negative mention(s)
0 Very Negative mention(s)
Positive
Alnylam Pharmaceuticals
6 Very Positive mention(s)
1 Positive mention(s)
9 Neutral mention(s)
4 Negative mention(s)
1 Very Negative mention(s)
Neutral

87.9% of Biogen shares are held by institutional investors. Comparatively, 93.0% of Alnylam Pharmaceuticals shares are held by institutional investors. 0.3% of Biogen shares are held by company insiders. Comparatively, 0.9% of Alnylam Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

Biogen has a beta of 0.16, meaning that its stock price is 84% less volatile than the broader market. Comparatively, Alnylam Pharmaceuticals has a beta of 0.27, meaning that its stock price is 73% less volatile than the broader market.

Biogen has a net margin of 13.81% compared to Alnylam Pharmaceuticals' net margin of 11.72%. Alnylam Pharmaceuticals' return on equity of 85.76% beat Biogen's return on equity.

Company Net Margins Return on Equity Return on Assets
Biogen13.81% 12.83% 8.01%
Alnylam Pharmaceuticals 11.72%85.76%10.32%

Biogen currently has a consensus target price of $220.04, suggesting a potential upside of 5.27%. Alnylam Pharmaceuticals has a consensus target price of $457.57, suggesting a potential upside of 58.84%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher probable upside, analysts plainly believe Alnylam Pharmaceuticals is more favorable than Biogen.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Biogen
2 Sell rating(s)
11 Hold rating(s)
17 Buy rating(s)
1 Strong Buy rating(s)
2.55
Alnylam Pharmaceuticals
0 Sell rating(s)
6 Hold rating(s)
18 Buy rating(s)
2 Strong Buy rating(s)
2.85

Summary

Alnylam Pharmaceuticals beats Biogen on 11 of the 17 factors compared between the two stocks.

How does Alnylam Pharmaceuticals compare to United Therapeutics?

Alnylam Pharmaceuticals (NASDAQ:ALNY) and United Therapeutics (NASDAQ:UTHR) are both large-cap medical companies, but which is the better business? We will contrast the two companies based on the strength of their institutional ownership, analyst recommendations, risk, profitability, media sentiment, dividends, valuation and earnings.

United Therapeutics has a net margin of 40.62% compared to Alnylam Pharmaceuticals' net margin of 11.72%. Alnylam Pharmaceuticals' return on equity of 85.76% beat United Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Alnylam Pharmaceuticals11.72% 85.76% 10.32%
United Therapeutics 40.62%19.24%17.25%

Alnylam Pharmaceuticals presently has a consensus target price of $457.57, indicating a potential upside of 58.84%. United Therapeutics has a consensus target price of $644.82, indicating a potential upside of 20.40%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher probable upside, research analysts plainly believe Alnylam Pharmaceuticals is more favorable than United Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alnylam Pharmaceuticals
0 Sell rating(s)
6 Hold rating(s)
18 Buy rating(s)
2 Strong Buy rating(s)
2.85
United Therapeutics
0 Sell rating(s)
2 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.83

93.0% of Alnylam Pharmaceuticals shares are owned by institutional investors. Comparatively, 94.1% of United Therapeutics shares are owned by institutional investors. 0.9% of Alnylam Pharmaceuticals shares are owned by company insiders. Comparatively, 8.6% of United Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

In the previous week, Alnylam Pharmaceuticals had 1 more articles in the media than United Therapeutics. MarketBeat recorded 24 mentions for Alnylam Pharmaceuticals and 23 mentions for United Therapeutics. United Therapeutics' average media sentiment score of 0.82 beat Alnylam Pharmaceuticals' score of 0.37 indicating that United Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Alnylam Pharmaceuticals
6 Very Positive mention(s)
1 Positive mention(s)
9 Neutral mention(s)
4 Negative mention(s)
1 Very Negative mention(s)
Neutral
United Therapeutics
13 Very Positive mention(s)
2 Positive mention(s)
0 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Alnylam Pharmaceuticals has a beta of 0.27, meaning that its share price is 73% less volatile than the broader market. Comparatively, United Therapeutics has a beta of 0.58, meaning that its share price is 42% less volatile than the broader market.

United Therapeutics has lower revenue, but higher earnings than Alnylam Pharmaceuticals. United Therapeutics is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alnylam Pharmaceuticals$3.71B10.36$313.75M$3.6678.70
United Therapeutics$3.18B7.14$1.33B$27.0919.77

Summary

Alnylam Pharmaceuticals beats United Therapeutics on 9 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding ALNY and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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ALNY vs. The Competition

MetricAlnylam PharmaceuticalsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$39.89B$3.71B$7.05B$12.61B
Dividend YieldN/A2.20%2.68%8.00%
P/E Ratio78.7020.8527.1124.26
Price / Sales10.36314.01589.14117.88
Price / Cash106.8561.9829.2249.36
Price / Book48.258.4910.756.29
Net Income$313.75M$23.83M$3.58B$330.66M
7 Day Performance-10.43%-3.56%-2.10%-1.35%
1 Month Performance1.84%6.31%3.29%-0.64%
1 Year Performance-8.77%48.30%26.32%19.08%

Alnylam Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
ALNY
Alnylam Pharmaceuticals
4.0996 of 5 stars
$288.06
-3.6%
$457.57
+58.8%
-8.5%$39.89B$3.71B78.702,770
GILD
Gilead Sciences
4.7993 of 5 stars
$129.61
-1.3%
$158.41
+22.2%
+19.8%$162.98B$29.44B17.6617,000
VRTX
Vertex Pharmaceuticals
3.9177 of 5 stars
$529.59
+0.3%
$555.91
+5.0%
+2.4%$134.02B$12.00B31.416,400
REGN
Regeneron Pharmaceuticals
4.6643 of 5 stars
$649.81
-0.7%
$817.65
+25.8%
+16.8%$69.17B$14.34B15.8315,410
BIIB
Biogen
3.4456 of 5 stars
$208.46
-3.5%
$217.67
+4.4%
+55.7%$31.91B$9.89B22.377,500

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This page (NASDAQ:ALNY) was last updated on 7/14/2026 by MarketBeat.com Staff.
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