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Alnylam Pharmaceuticals (ALNY) Competitors

Alnylam Pharmaceuticals logo
$248.68 +1.17 (+0.47%)
Closing price 09/11/2026 04:00 PM Eastern
Extended Trading
$250.12 +1.44 (+0.58%)
As of 09/11/2026 07:30 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

ALNY vs. VRTX, REGN, ARGX, MRNA, and NTRA

Should you buy Alnylam Pharmaceuticals stock or one of its competitors? Alnylam Pharmaceuticals's main competitors and comparable companies include Vertex Pharmaceuticals (VRTX), Regeneron Pharmaceuticals (REGN), argenex (ARGX), Moderna (MRNA), and Natera (NTRA). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Alnylam Pharmaceuticals compare to Vertex Pharmaceuticals?

Vertex Pharmaceuticals (NASDAQ:VRTX) and Alnylam Pharmaceuticals (NASDAQ:ALNY) are both large-cap healthcare companies, but which is the better stock? We will contrast the two companies based on the strength of their valuation, institutional ownership, risk, earnings, analyst recommendations, dividends, media sentiment and profitability.

Vertex Pharmaceuticals currently has a consensus price target of $570.83, suggesting a potential upside of 10.75%. Alnylam Pharmaceuticals has a consensus price target of $376.67, suggesting a potential upside of 51.47%. Given Alnylam Pharmaceuticals' higher probable upside, analysts plainly believe Alnylam Pharmaceuticals is more favorable than Vertex Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Vertex Pharmaceuticals
0 Sell rating(s)
2 Hold rating(s)
20 Buy rating(s)
1 Strong Buy rating(s)
2.96
Alnylam Pharmaceuticals
0 Sell rating(s)
5 Hold rating(s)
17 Buy rating(s)
2 Strong Buy rating(s)
2.88

Vertex Pharmaceuticals has a beta of 0.32, indicating that its stock price is 68% less volatile than the broader market. Comparatively, Alnylam Pharmaceuticals has a beta of 0.31, indicating that its stock price is 69% less volatile than the broader market.

Vertex Pharmaceuticals has higher revenue and earnings than Alnylam Pharmaceuticals. Vertex Pharmaceuticals is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Vertex Pharmaceuticals$12.00B10.90$3.95B$17.1830.00
Alnylam Pharmaceuticals$3.71B8.96$313.75M$5.3846.22

Vertex Pharmaceuticals has a net margin of 35.00% compared to Alnylam Pharmaceuticals' net margin of 15.26%. Alnylam Pharmaceuticals' return on equity of 84.93% beat Vertex Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Vertex Pharmaceuticals35.00% 23.09% 16.72%
Alnylam Pharmaceuticals 15.26%84.93%14.30%

91.0% of Vertex Pharmaceuticals shares are held by institutional investors. Comparatively, 93.0% of Alnylam Pharmaceuticals shares are held by institutional investors. 0.2% of Vertex Pharmaceuticals shares are held by company insiders. Comparatively, 0.9% of Alnylam Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

In the previous week, Vertex Pharmaceuticals had 16 more articles in the media than Alnylam Pharmaceuticals. MarketBeat recorded 30 mentions for Vertex Pharmaceuticals and 14 mentions for Alnylam Pharmaceuticals. Alnylam Pharmaceuticals' average media sentiment score of 1.24 beat Vertex Pharmaceuticals' score of 0.80 indicating that Alnylam Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Vertex Pharmaceuticals
16 Very Positive mention(s)
5 Positive mention(s)
3 Neutral mention(s)
3 Negative mention(s)
1 Very Negative mention(s)
Positive
Alnylam Pharmaceuticals
8 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Vertex Pharmaceuticals beats Alnylam Pharmaceuticals on 10 of the 17 factors compared between the two stocks.

How does Alnylam Pharmaceuticals compare to Regeneron Pharmaceuticals?

Alnylam Pharmaceuticals (NASDAQ:ALNY) and Regeneron Pharmaceuticals (NASDAQ:REGN) are both large-cap healthcare companies, but which is the better investment? We will contrast the two businesses based on the strength of their analyst recommendations, earnings, profitability, media sentiment, institutional ownership, dividends, valuation and risk.

Alnylam Pharmaceuticals has a beta of 0.31, indicating that its stock price is 69% less volatile than the broader market. Comparatively, Regeneron Pharmaceuticals has a beta of 0.2, indicating that its stock price is 80% less volatile than the broader market.

Regeneron Pharmaceuticals has higher revenue and earnings than Alnylam Pharmaceuticals. Regeneron Pharmaceuticals is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alnylam Pharmaceuticals$3.71B8.96$313.75M$5.3846.22
Regeneron Pharmaceuticals$14.34B5.61$4.50B$40.4619.32

Regeneron Pharmaceuticals has a net margin of 27.86% compared to Alnylam Pharmaceuticals' net margin of 15.26%. Alnylam Pharmaceuticals' return on equity of 84.93% beat Regeneron Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Alnylam Pharmaceuticals15.26% 84.93% 14.30%
Regeneron Pharmaceuticals 27.86%13.47%10.34%

In the previous week, Regeneron Pharmaceuticals had 35 more articles in the media than Alnylam Pharmaceuticals. MarketBeat recorded 49 mentions for Regeneron Pharmaceuticals and 14 mentions for Alnylam Pharmaceuticals. Alnylam Pharmaceuticals' average media sentiment score of 1.24 beat Regeneron Pharmaceuticals' score of 0.65 indicating that Alnylam Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Alnylam Pharmaceuticals
8 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Regeneron Pharmaceuticals
19 Very Positive mention(s)
4 Positive mention(s)
22 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Positive

93.0% of Alnylam Pharmaceuticals shares are owned by institutional investors. Comparatively, 83.3% of Regeneron Pharmaceuticals shares are owned by institutional investors. 0.9% of Alnylam Pharmaceuticals shares are owned by insiders. Comparatively, 7.0% of Regeneron Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

Alnylam Pharmaceuticals currently has a consensus target price of $376.67, indicating a potential upside of 51.47%. Regeneron Pharmaceuticals has a consensus target price of $802.18, indicating a potential upside of 2.65%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher probable upside, research analysts clearly believe Alnylam Pharmaceuticals is more favorable than Regeneron Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alnylam Pharmaceuticals
0 Sell rating(s)
5 Hold rating(s)
17 Buy rating(s)
2 Strong Buy rating(s)
2.88
Regeneron Pharmaceuticals
0 Sell rating(s)
10 Hold rating(s)
14 Buy rating(s)
0 Strong Buy rating(s)
2.58

Summary

Alnylam Pharmaceuticals beats Regeneron Pharmaceuticals on 11 of the 17 factors compared between the two stocks.

How does Alnylam Pharmaceuticals compare to argenex?

Alnylam Pharmaceuticals (NASDAQ:ALNY) and argenex (NASDAQ:ARGX) are both large-cap healthcare companies, but which is the better business? We will compare the two companies based on the strength of their institutional ownership, earnings, media sentiment, valuation, analyst recommendations, risk, dividends and profitability.

Alnylam Pharmaceuticals has a beta of 0.31, suggesting that its share price is 69% less volatile than the broader market. Comparatively, argenex has a beta of 0.47, suggesting that its share price is 53% less volatile than the broader market.

Alnylam Pharmaceuticals currently has a consensus price target of $376.67, suggesting a potential upside of 51.47%. argenex has a consensus price target of $1,158.61, suggesting a potential upside of 17.70%. Given Alnylam Pharmaceuticals' higher possible upside, equities analysts plainly believe Alnylam Pharmaceuticals is more favorable than argenex.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alnylam Pharmaceuticals
0 Sell rating(s)
5 Hold rating(s)
17 Buy rating(s)
2 Strong Buy rating(s)
2.88
argenex
0 Sell rating(s)
5 Hold rating(s)
17 Buy rating(s)
2 Strong Buy rating(s)
2.88

argenex has higher revenue and earnings than Alnylam Pharmaceuticals. argenex is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alnylam Pharmaceuticals$3.71B8.96$313.75M$5.3846.22
argenex$4.25B14.50$1.29B$26.0437.80

93.0% of Alnylam Pharmaceuticals shares are owned by institutional investors. Comparatively, 60.3% of argenex shares are owned by institutional investors. 0.9% of Alnylam Pharmaceuticals shares are owned by company insiders. Comparatively, 2.4% of argenex shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

In the previous week, Alnylam Pharmaceuticals had 8 more articles in the media than argenex. MarketBeat recorded 14 mentions for Alnylam Pharmaceuticals and 6 mentions for argenex. Alnylam Pharmaceuticals' average media sentiment score of 1.24 beat argenex's score of 0.83 indicating that Alnylam Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Alnylam Pharmaceuticals
8 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
argenex
2 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

argenex has a net margin of 32.19% compared to Alnylam Pharmaceuticals' net margin of 15.26%. Alnylam Pharmaceuticals' return on equity of 84.93% beat argenex's return on equity.

Company Net Margins Return on Equity Return on Assets
Alnylam Pharmaceuticals15.26% 84.93% 14.30%
argenex 32.19%43.59%36.66%

Summary

argenex beats Alnylam Pharmaceuticals on 8 of the 14 factors compared between the two stocks.

How does Alnylam Pharmaceuticals compare to Moderna?

Alnylam Pharmaceuticals (NASDAQ:ALNY) and Moderna (NASDAQ:MRNA) are both large-cap healthcare companies, but which is the superior investment? We will compare the two businesses based on the strength of their dividends, valuation, media sentiment, earnings, analyst recommendations, institutional ownership, profitability and risk.

93.0% of Alnylam Pharmaceuticals shares are owned by institutional investors. Comparatively, 75.3% of Moderna shares are owned by institutional investors. 0.9% of Alnylam Pharmaceuticals shares are owned by company insiders. Comparatively, 10.8% of Moderna shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company is poised for long-term growth.

Alnylam Pharmaceuticals currently has a consensus target price of $376.67, suggesting a potential upside of 51.47%. Moderna has a consensus target price of $76.72, suggesting a potential downside of 46.71%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher possible upside, analysts clearly believe Alnylam Pharmaceuticals is more favorable than Moderna.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alnylam Pharmaceuticals
0 Sell rating(s)
5 Hold rating(s)
17 Buy rating(s)
2 Strong Buy rating(s)
2.88
Moderna
5 Sell rating(s)
12 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.08

Alnylam Pharmaceuticals has higher revenue and earnings than Moderna. Moderna is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alnylam Pharmaceuticals$3.71B8.96$313.75M$5.3846.22
Moderna$1.94B29.57-$2.82B-$7.99N/A

Alnylam Pharmaceuticals has a beta of 0.31, meaning that its share price is 69% less volatile than the broader market. Comparatively, Moderna has a beta of 1.1, meaning that its share price is 10% more volatile than the broader market.

In the previous week, Moderna had 12 more articles in the media than Alnylam Pharmaceuticals. MarketBeat recorded 26 mentions for Moderna and 14 mentions for Alnylam Pharmaceuticals. Alnylam Pharmaceuticals' average media sentiment score of 1.24 beat Moderna's score of 0.56 indicating that Alnylam Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Alnylam Pharmaceuticals
8 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Moderna
9 Very Positive mention(s)
8 Positive mention(s)
5 Neutral mention(s)
2 Negative mention(s)
1 Very Negative mention(s)
Positive

Alnylam Pharmaceuticals has a net margin of 15.26% compared to Moderna's net margin of -141.43%. Alnylam Pharmaceuticals' return on equity of 84.93% beat Moderna's return on equity.

Company Net Margins Return on Equity Return on Assets
Alnylam Pharmaceuticals15.26% 84.93% 14.30%
Moderna -141.43%-28.30%-19.39%

Summary

Alnylam Pharmaceuticals beats Moderna on 13 of the 17 factors compared between the two stocks.

How does Alnylam Pharmaceuticals compare to Natera?

Alnylam Pharmaceuticals (NASDAQ:ALNY) and Natera (NASDAQ:NTRA) are both large-cap healthcare companies, but which is the superior stock? We will contrast the two companies based on the strength of their earnings, analyst recommendations, institutional ownership, profitability, valuation, media sentiment, dividends and risk.

Alnylam Pharmaceuticals presently has a consensus price target of $376.67, suggesting a potential upside of 51.47%. Natera has a consensus price target of $330.83, suggesting a potential upside of 0.58%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher probable upside, equities analysts plainly believe Alnylam Pharmaceuticals is more favorable than Natera.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alnylam Pharmaceuticals
0 Sell rating(s)
5 Hold rating(s)
17 Buy rating(s)
2 Strong Buy rating(s)
2.88
Natera
1 Sell rating(s)
4 Hold rating(s)
16 Buy rating(s)
2 Strong Buy rating(s)
2.83

In the previous week, Natera had 5 more articles in the media than Alnylam Pharmaceuticals. MarketBeat recorded 19 mentions for Natera and 14 mentions for Alnylam Pharmaceuticals. Alnylam Pharmaceuticals' average media sentiment score of 1.24 beat Natera's score of 1.14 indicating that Alnylam Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Alnylam Pharmaceuticals
8 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Natera
11 Very Positive mention(s)
1 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Alnylam Pharmaceuticals has a net margin of 15.26% compared to Natera's net margin of -7.11%. Alnylam Pharmaceuticals' return on equity of 84.93% beat Natera's return on equity.

Company Net Margins Return on Equity Return on Assets
Alnylam Pharmaceuticals15.26% 84.93% 14.30%
Natera -7.11%-11.38%-7.87%

Alnylam Pharmaceuticals has a beta of 0.31, meaning that its share price is 69% less volatile than the broader market. Comparatively, Natera has a beta of 1.54, meaning that its share price is 54% more volatile than the broader market.

93.0% of Alnylam Pharmaceuticals shares are owned by institutional investors. Comparatively, 99.9% of Natera shares are owned by institutional investors. 0.9% of Alnylam Pharmaceuticals shares are owned by insiders. Comparatively, 5.1% of Natera shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

Alnylam Pharmaceuticals has higher revenue and earnings than Natera. Natera is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alnylam Pharmaceuticals$3.71B8.96$313.75M$5.3846.22
Natera$2.31B20.56-$208.16M-$1.36N/A

Summary

Alnylam Pharmaceuticals beats Natera on 11 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding ALNY and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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ALNY vs. The Competition

MetricAlnylam PharmaceuticalsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$33.28B$3.86B$7.17B$12.85B
Dividend YieldN/A3.66%2.57%11.71%
P/E Ratio46.2214.18274.9425.33
Price / Sales8.961,375.01685.45111.15
Price / Cash88.94106.5076.6551.52
Price / Book41.6515.1210.336.20
Net Income$313.75M-$22.86M$3.50B$358.50M
7 Day Performance-6.55%-4.34%-3.32%-2.35%
1 Month Performance11.04%-0.02%-0.41%-2.77%
1 Year Performance-46.62%40.64%19.21%7.63%

Alnylam Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
ALNY
Alnylam Pharmaceuticals
4.4613 of 5 stars
$248.68
+0.5%
$376.67
+51.5%
-46.9%$33.28B$3.71B46.222,770
VRTX
Vertex Pharmaceuticals
3.5394 of 5 stars
$515.87
+0.3%
$570.83
+10.7%
+29.7%$131.00B$12.00B30.046,400
REGN
Regeneron Pharmaceuticals
3.8038 of 5 stars
$783.21
-1.3%
$802.18
+2.4%
+37.5%$80.64B$14.34B19.3615,410
ARGX
argenex
4.5495 of 5 stars
$991.98
+0.8%
$1,158.61
+16.8%
+28.9%$62.15B$5.23B38.151,863
MRNA
Moderna
2.1298 of 5 stars
$147.46
+7.9%
$76.72
-48.0%
+467.0%$59.04B$1.94BN/A4,700

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This page (NASDAQ:ALNY) was last updated on 9/12/2026 by MarketBeat.com Staff.
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