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Alnylam Pharmaceuticals (ALNY) Competitors

Alnylam Pharmaceuticals logo
$219.72 -11.46 (-4.96%)
Closing price 10/2/2026 04:00 PM Eastern
Extended Trading
$220.10 +0.38 (+0.17%)
As of 10/2/2026 07:49 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

ALNY vs. REGN, MRNA, NTRA, ARGX, and RVMD

Should you buy Alnylam Pharmaceuticals stock or one of its competitors? Alnylam Pharmaceuticals's main competitors and comparable companies include Regeneron Pharmaceuticals (REGN), Moderna (MRNA), Natera (NTRA), argenex (ARGX), and Revolution Medicines (RVMD). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Alnylam Pharmaceuticals compare to Regeneron Pharmaceuticals?

Regeneron Pharmaceuticals (NASDAQ:REGN) and Alnylam Pharmaceuticals (NASDAQ:ALNY) are both large-cap healthcare companies, but which is the better business? We will compare the two businesses based on the strength of their earnings, media sentiment, profitability, dividends, analyst recommendations, risk, valuation and institutional ownership.

Regeneron Pharmaceuticals has higher revenue and earnings than Alnylam Pharmaceuticals. Regeneron Pharmaceuticals is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Regeneron Pharmaceuticals$14.34B5.28$4.50B$40.4618.17
Alnylam Pharmaceuticals$3.71B7.92$313.75M$5.3840.84

Regeneron Pharmaceuticals has a net margin of 27.86% compared to Alnylam Pharmaceuticals' net margin of 15.26%. Alnylam Pharmaceuticals' return on equity of 84.93% beat Regeneron Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Regeneron Pharmaceuticals27.86% 13.47% 10.34%
Alnylam Pharmaceuticals 15.26%84.93%14.30%

Regeneron Pharmaceuticals has a beta of 0.16, indicating that its stock price is 84% less volatile than the broader market. Comparatively, Alnylam Pharmaceuticals has a beta of 0.28, indicating that its stock price is 72% less volatile than the broader market.

Regeneron Pharmaceuticals presently has a consensus price target of $809.50, indicating a potential upside of 10.11%. Alnylam Pharmaceuticals has a consensus price target of $366.90, indicating a potential upside of 66.99%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher possible upside, analysts clearly believe Alnylam Pharmaceuticals is more favorable than Regeneron Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Regeneron Pharmaceuticals
0 Sell rating(s)
9 Hold rating(s)
16 Buy rating(s)
1 Strong Buy rating(s)
2.69
Alnylam Pharmaceuticals
0 Sell rating(s)
6 Hold rating(s)
16 Buy rating(s)
2 Strong Buy rating(s)
2.83

83.3% of Regeneron Pharmaceuticals shares are held by institutional investors. Comparatively, 93.0% of Alnylam Pharmaceuticals shares are held by institutional investors. 7.0% of Regeneron Pharmaceuticals shares are held by insiders. Comparatively, 0.9% of Alnylam Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

In the previous week, Regeneron Pharmaceuticals had 34 more articles in the media than Alnylam Pharmaceuticals. MarketBeat recorded 42 mentions for Regeneron Pharmaceuticals and 8 mentions for Alnylam Pharmaceuticals. Regeneron Pharmaceuticals' average media sentiment score of 0.51 beat Alnylam Pharmaceuticals' score of 0.19 indicating that Regeneron Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Regeneron Pharmaceuticals
13 Very Positive mention(s)
7 Positive mention(s)
13 Neutral mention(s)
3 Negative mention(s)
2 Very Negative mention(s)
Positive
Alnylam Pharmaceuticals
1 Very Positive mention(s)
2 Positive mention(s)
3 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

Alnylam Pharmaceuticals beats Regeneron Pharmaceuticals on 9 of the 16 factors compared between the two stocks.

How does Alnylam Pharmaceuticals compare to Moderna?

Alnylam Pharmaceuticals (NASDAQ:ALNY) and Moderna (NASDAQ:MRNA) are both large-cap healthcare companies, but which is the superior business? We will compare the two companies based on the strength of their earnings, dividends, risk, institutional ownership, media sentiment, valuation, profitability and analyst recommendations.

Alnylam Pharmaceuticals has a beta of 0.28, indicating that its share price is 72% less volatile than the broader market. Comparatively, Moderna has a beta of 1.09, indicating that its share price is 9% more volatile than the broader market.

In the previous week, Moderna had 32 more articles in the media than Alnylam Pharmaceuticals. MarketBeat recorded 40 mentions for Moderna and 8 mentions for Alnylam Pharmaceuticals. Moderna's average media sentiment score of 0.27 beat Alnylam Pharmaceuticals' score of 0.19 indicating that Moderna is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Alnylam Pharmaceuticals
1 Very Positive mention(s)
2 Positive mention(s)
3 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
Moderna
7 Very Positive mention(s)
15 Positive mention(s)
8 Neutral mention(s)
9 Negative mention(s)
1 Very Negative mention(s)
Neutral

Alnylam Pharmaceuticals presently has a consensus target price of $366.90, suggesting a potential upside of 66.99%. Moderna has a consensus target price of $77.83, suggesting a potential downside of 59.04%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher probable upside, equities analysts clearly believe Alnylam Pharmaceuticals is more favorable than Moderna.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alnylam Pharmaceuticals
0 Sell rating(s)
6 Hold rating(s)
16 Buy rating(s)
2 Strong Buy rating(s)
2.83
Moderna
5 Sell rating(s)
13 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.08

93.0% of Alnylam Pharmaceuticals shares are held by institutional investors. Comparatively, 75.3% of Moderna shares are held by institutional investors. 0.9% of Alnylam Pharmaceuticals shares are held by company insiders. Comparatively, 10.8% of Moderna shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

Alnylam Pharmaceuticals has a net margin of 15.26% compared to Moderna's net margin of -141.43%. Alnylam Pharmaceuticals' return on equity of 84.93% beat Moderna's return on equity.

Company Net Margins Return on Equity Return on Assets
Alnylam Pharmaceuticals15.26% 84.93% 14.30%
Moderna -141.43%-28.30%-19.39%

Alnylam Pharmaceuticals has higher revenue and earnings than Moderna. Moderna is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alnylam Pharmaceuticals$3.71B7.92$313.75M$5.3840.84
Moderna$1.94B39.02-$2.82B-$7.99N/A

Summary

Alnylam Pharmaceuticals beats Moderna on 12 of the 17 factors compared between the two stocks.

How does Alnylam Pharmaceuticals compare to Natera?

Natera (NASDAQ:NTRA) and Alnylam Pharmaceuticals (NASDAQ:ALNY) are both large-cap healthcare companies, but which is the better investment? We will contrast the two businesses based on the strength of their profitability, earnings, analyst recommendations, valuation, institutional ownership, dividends, risk and media sentiment.

Natera presently has a consensus price target of $341.55, indicating a potential downside of 16.77%. Alnylam Pharmaceuticals has a consensus price target of $366.90, indicating a potential upside of 66.99%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher probable upside, analysts plainly believe Alnylam Pharmaceuticals is more favorable than Natera.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Natera
1 Sell rating(s)
4 Hold rating(s)
16 Buy rating(s)
2 Strong Buy rating(s)
2.83
Alnylam Pharmaceuticals
0 Sell rating(s)
6 Hold rating(s)
16 Buy rating(s)
2 Strong Buy rating(s)
2.83

Alnylam Pharmaceuticals has a net margin of 15.26% compared to Natera's net margin of -7.11%. Alnylam Pharmaceuticals' return on equity of 84.93% beat Natera's return on equity.

Company Net Margins Return on Equity Return on Assets
Natera-7.11% -11.38% -7.87%
Alnylam Pharmaceuticals 15.26%84.93%14.30%

In the previous week, Alnylam Pharmaceuticals had 2 more articles in the media than Natera. MarketBeat recorded 8 mentions for Alnylam Pharmaceuticals and 6 mentions for Natera. Natera's average media sentiment score of 0.50 beat Alnylam Pharmaceuticals' score of 0.19 indicating that Natera is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Natera
2 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Alnylam Pharmaceuticals
1 Very Positive mention(s)
2 Positive mention(s)
3 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

Alnylam Pharmaceuticals has higher revenue and earnings than Natera. Natera is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Natera$2.31B25.65-$208.16M-$1.36N/A
Alnylam Pharmaceuticals$3.71B7.92$313.75M$5.3840.84

Natera has a beta of 1.5, indicating that its stock price is 50% more volatile than the broader market. Comparatively, Alnylam Pharmaceuticals has a beta of 0.28, indicating that its stock price is 72% less volatile than the broader market.

99.9% of Natera shares are owned by institutional investors. Comparatively, 93.0% of Alnylam Pharmaceuticals shares are owned by institutional investors. 5.1% of Natera shares are owned by company insiders. Comparatively, 0.9% of Alnylam Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Summary

Alnylam Pharmaceuticals beats Natera on 10 of the 15 factors compared between the two stocks.

How does Alnylam Pharmaceuticals compare to argenex?

Alnylam Pharmaceuticals (NASDAQ:ALNY) and argenex (NASDAQ:ARGX) are both large-cap healthcare companies, but which is the superior business? We will contrast the two businesses based on the strength of their institutional ownership, media sentiment, valuation, profitability, risk, dividends, earnings and analyst recommendations.

In the previous week, Alnylam Pharmaceuticals had 5 more articles in the media than argenex. MarketBeat recorded 8 mentions for Alnylam Pharmaceuticals and 3 mentions for argenex. Alnylam Pharmaceuticals' average media sentiment score of 0.19 beat argenex's score of 0.05 indicating that Alnylam Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Alnylam Pharmaceuticals
1 Very Positive mention(s)
2 Positive mention(s)
3 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
argenex
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

Alnylam Pharmaceuticals presently has a consensus target price of $366.90, indicating a potential upside of 66.99%. argenex has a consensus target price of $1,158.61, indicating a potential upside of 26.04%. Given Alnylam Pharmaceuticals' higher probable upside, analysts clearly believe Alnylam Pharmaceuticals is more favorable than argenex.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alnylam Pharmaceuticals
0 Sell rating(s)
6 Hold rating(s)
16 Buy rating(s)
2 Strong Buy rating(s)
2.83
argenex
0 Sell rating(s)
5 Hold rating(s)
17 Buy rating(s)
2 Strong Buy rating(s)
2.88

argenex has a net margin of 32.19% compared to Alnylam Pharmaceuticals' net margin of 15.26%. Alnylam Pharmaceuticals' return on equity of 84.93% beat argenex's return on equity.

Company Net Margins Return on Equity Return on Assets
Alnylam Pharmaceuticals15.26% 84.93% 14.30%
argenex 32.19%43.59%36.66%

Alnylam Pharmaceuticals has a beta of 0.28, suggesting that its share price is 72% less volatile than the broader market. Comparatively, argenex has a beta of 0.45, suggesting that its share price is 55% less volatile than the broader market.

93.0% of Alnylam Pharmaceuticals shares are owned by institutional investors. Comparatively, 60.3% of argenex shares are owned by institutional investors. 0.9% of Alnylam Pharmaceuticals shares are owned by insiders. Comparatively, 2.4% of argenex shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

argenex has higher revenue and earnings than Alnylam Pharmaceuticals. argenex is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alnylam Pharmaceuticals$3.71B7.92$313.75M$5.3840.84
argenex$5.23B11.00$1.29B$26.0435.30

Summary

argenex beats Alnylam Pharmaceuticals on 10 of the 16 factors compared between the two stocks.

How does Alnylam Pharmaceuticals compare to Revolution Medicines?

Revolution Medicines (NASDAQ:RVMD) and Alnylam Pharmaceuticals (NASDAQ:ALNY) are both large-cap healthcare companies, but which is the better stock? We will compare the two businesses based on the strength of their risk, valuation, profitability, earnings, media sentiment, dividends, analyst recommendations and institutional ownership.

Revolution Medicines presently has a consensus price target of $234.33, indicating a potential upside of 13.40%. Alnylam Pharmaceuticals has a consensus price target of $366.90, indicating a potential upside of 66.99%. Given Alnylam Pharmaceuticals' higher probable upside, analysts plainly believe Alnylam Pharmaceuticals is more favorable than Revolution Medicines.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Revolution Medicines
1 Sell rating(s)
1 Hold rating(s)
20 Buy rating(s)
2 Strong Buy rating(s)
2.96
Alnylam Pharmaceuticals
0 Sell rating(s)
6 Hold rating(s)
16 Buy rating(s)
2 Strong Buy rating(s)
2.83

Alnylam Pharmaceuticals has a net margin of 15.26% compared to Revolution Medicines' net margin of 0.00%. Alnylam Pharmaceuticals' return on equity of 84.93% beat Revolution Medicines' return on equity.

Company Net Margins Return on Equity Return on Assets
Revolution MedicinesN/A -88.20% -57.85%
Alnylam Pharmaceuticals 15.26%84.93%14.30%

Alnylam Pharmaceuticals has higher revenue and earnings than Revolution Medicines. Revolution Medicines is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Revolution Medicines$11.58M3,824.80-$1.13B-$8.82N/A
Alnylam Pharmaceuticals$3.71B7.92$313.75M$5.3840.84

In the previous week, Revolution Medicines had 6 more articles in the media than Alnylam Pharmaceuticals. MarketBeat recorded 14 mentions for Revolution Medicines and 8 mentions for Alnylam Pharmaceuticals. Revolution Medicines' average media sentiment score of 0.57 beat Alnylam Pharmaceuticals' score of 0.19 indicating that Revolution Medicines is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Revolution Medicines
2 Very Positive mention(s)
1 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Alnylam Pharmaceuticals
1 Very Positive mention(s)
2 Positive mention(s)
3 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

Revolution Medicines has a beta of 1.4, indicating that its stock price is 40% more volatile than the broader market. Comparatively, Alnylam Pharmaceuticals has a beta of 0.28, indicating that its stock price is 72% less volatile than the broader market.

94.3% of Revolution Medicines shares are owned by institutional investors. Comparatively, 93.0% of Alnylam Pharmaceuticals shares are owned by institutional investors. 7.6% of Revolution Medicines shares are owned by insiders. Comparatively, 0.9% of Alnylam Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

Summary

Revolution Medicines and Alnylam Pharmaceuticals tied by winning 8 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding ALNY and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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ALNY vs. The Competition

MetricAlnylam PharmaceuticalsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$29.40B$3.86B$7.16B$13.28B
Dividend YieldN/A3.65%2.54%17.32%
P/E Ratio40.847.72215.5321.44
Price / Sales7.921,295.82609.3192.00
Price / Cash78.58123.3978.8752.62
Price / Book36.8016.6310.936.31
Net Income$313.75M-$22.71M$3.51B$362.16M
7 Day Performance-14.16%-2.99%-2.00%-1.66%
1 Month Performance-16.93%-10.60%-6.15%-4.50%
1 Year Performance-51.85%19.44%7.44%2.06%

Alnylam Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
ALNY
Alnylam Pharmaceuticals
3.6143 of 5 stars
$219.72
-5.0%
$366.90
+67.0%
-52.3%$29.40B$3.71B40.842,770
REGN
Regeneron Pharmaceuticals
4.2665 of 5 stars
$736.61
+0.2%
$809.50
+9.9%
+22.5%$75.86B$14.34B18.2115,410
MRNA
Moderna
1.9454 of 5 stars
$188.65
-0.2%
$77.83
-58.7%
+569.8%$75.38B$1.94BN/A4,700
NTRA
Natera
2.0465 of 5 stars
$406.18
-0.6%
$341.55
-15.9%
+156.1%$58.15B$2.31BN/A6,140
ARGX
argenex
4.5204 of 5 stars
$918.17
-1.9%
$1,158.61
+26.2%
+16.1%$57.42B$4.25B35.251,863

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This page (NASDAQ:ALNY) was last updated on 10/3/2026 by MarketBeat.com Staff.
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