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Biogen (BIIB) Competitors

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$218.50 -3.00 (-1.35%)
As of 08/28/2026 04:00 PM Eastern

BIIB vs. AMGN, DNLI, GILD, IONS, and MRNA

Should you buy Biogen stock or one of its competitors? Biogen's main competitors and comparable companies include Amgen (AMGN), Denali Therapeutics (DNLI), Gilead Sciences (GILD), Ionis Pharmaceuticals (IONS), and Moderna (MRNA). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Biogen compare to Amgen?

Amgen (NASDAQ:AMGN) and Biogen (NASDAQ:BIIB) are both large-cap healthcare companies, but which is the better investment? We will contrast the two businesses based on the strength of their institutional ownership, profitability, earnings, valuation, risk, media sentiment, dividends and analyst recommendations.

Amgen has higher revenue and earnings than Biogen. Amgen is trading at a lower price-to-earnings ratio than Biogen, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Amgen$38.10B6.14$7.71B$16.0926.88
Biogen$10.03B3.22$1.29B$5.6538.67

76.5% of Amgen shares are owned by institutional investors. Comparatively, 87.9% of Biogen shares are owned by institutional investors. 0.9% of Amgen shares are owned by insiders. Comparatively, 0.3% of Biogen shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Amgen has a beta of 0.41, suggesting that its stock price is 59% less volatile than the broader market. Comparatively, Biogen has a beta of 0.17, suggesting that its stock price is 83% less volatile than the broader market.

Amgen has a net margin of 22.95% compared to Biogen's net margin of 8.32%. Amgen's return on equity of 124.14% beat Biogen's return on equity.

Company Net Margins Return on Equity Return on Assets
Amgen22.95% 124.14% 13.18%
Biogen 8.32%11.18%6.88%

In the previous week, Amgen had 32 more articles in the media than Biogen. MarketBeat recorded 70 mentions for Amgen and 38 mentions for Biogen. Amgen's average media sentiment score of 1.40 beat Biogen's score of 1.25 indicating that Amgen is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Amgen
61 Very Positive mention(s)
3 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Biogen
28 Very Positive mention(s)
2 Positive mention(s)
6 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Amgen presently has a consensus price target of $380.43, indicating a potential downside of 12.02%. Biogen has a consensus price target of $227.79, indicating a potential upside of 4.25%. Given Biogen's stronger consensus rating and higher probable upside, analysts clearly believe Biogen is more favorable than Amgen.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Amgen
3 Sell rating(s)
14 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.39
Biogen
1 Sell rating(s)
13 Hold rating(s)
18 Buy rating(s)
1 Strong Buy rating(s)
2.58

Summary

Amgen beats Biogen on 11 of the 16 factors compared between the two stocks.

How does Biogen compare to Denali Therapeutics?

Biogen (NASDAQ:BIIB) and Denali Therapeutics (NASDAQ:DNLI) are both healthcare companies, but which is the superior stock? We will contrast the two businesses based on the strength of their media sentiment, dividends, institutional ownership, profitability, risk, earnings, analyst recommendations and valuation.

Biogen currently has a consensus target price of $227.79, indicating a potential upside of 4.25%. Denali Therapeutics has a consensus target price of $35.85, indicating a potential upside of 49.36%. Given Denali Therapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Denali Therapeutics is more favorable than Biogen.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Biogen
1 Sell rating(s)
13 Hold rating(s)
18 Buy rating(s)
1 Strong Buy rating(s)
2.58
Denali Therapeutics
1 Sell rating(s)
2 Hold rating(s)
14 Buy rating(s)
0 Strong Buy rating(s)
2.76

Biogen has a net margin of 8.32% compared to Denali Therapeutics' net margin of 0.00%. Biogen's return on equity of 11.18% beat Denali Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Biogen8.32% 11.18% 6.88%
Denali Therapeutics N/A -55.27%-44.24%

In the previous week, Biogen had 32 more articles in the media than Denali Therapeutics. MarketBeat recorded 38 mentions for Biogen and 6 mentions for Denali Therapeutics. Denali Therapeutics' average media sentiment score of 1.73 beat Biogen's score of 1.25 indicating that Denali Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Biogen
28 Very Positive mention(s)
2 Positive mention(s)
6 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Denali Therapeutics
5 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive

Biogen has higher revenue and earnings than Denali Therapeutics. Denali Therapeutics is trading at a lower price-to-earnings ratio than Biogen, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Biogen$10.03B3.22$1.29B$5.6538.67
Denali Therapeutics$330.53M11.61-$512.54M-$2.84N/A

87.9% of Biogen shares are owned by institutional investors. Comparatively, 92.9% of Denali Therapeutics shares are owned by institutional investors. 0.3% of Biogen shares are owned by company insiders. Comparatively, 9.7% of Denali Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

Biogen has a beta of 0.17, suggesting that its share price is 83% less volatile than the broader market. Comparatively, Denali Therapeutics has a beta of 1.01, suggesting that its share price is 1% more volatile than the broader market.

Summary

Biogen beats Denali Therapeutics on 10 of the 17 factors compared between the two stocks.

How does Biogen compare to Gilead Sciences?

Biogen (NASDAQ:BIIB) and Gilead Sciences (NASDAQ:GILD) are both large-cap healthcare companies, but which is the superior business? We will contrast the two businesses based on the strength of their analyst recommendations, media sentiment, profitability, earnings, institutional ownership, valuation, dividends and risk.

Biogen currently has a consensus price target of $227.79, indicating a potential upside of 4.25%. Gilead Sciences has a consensus price target of $158.04, indicating a potential upside of 8.48%. Given Gilead Sciences' stronger consensus rating and higher possible upside, analysts clearly believe Gilead Sciences is more favorable than Biogen.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Biogen
1 Sell rating(s)
13 Hold rating(s)
18 Buy rating(s)
1 Strong Buy rating(s)
2.58
Gilead Sciences
0 Sell rating(s)
5 Hold rating(s)
24 Buy rating(s)
0 Strong Buy rating(s)
2.83

87.9% of Biogen shares are owned by institutional investors. Comparatively, 83.7% of Gilead Sciences shares are owned by institutional investors. 0.3% of Biogen shares are owned by insiders. Comparatively, 0.3% of Gilead Sciences shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

Biogen has a beta of 0.17, suggesting that its share price is 83% less volatile than the broader market. Comparatively, Gilead Sciences has a beta of 0.32, suggesting that its share price is 68% less volatile than the broader market.

Biogen has a net margin of 8.32% compared to Gilead Sciences' net margin of -10.64%. Biogen's return on equity of 11.18% beat Gilead Sciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Biogen8.32% 11.18% 6.88%
Gilead Sciences -10.64%-2.11%-0.75%

In the previous week, Gilead Sciences had 41 more articles in the media than Biogen. MarketBeat recorded 79 mentions for Gilead Sciences and 38 mentions for Biogen. Gilead Sciences' average media sentiment score of 1.37 beat Biogen's score of 1.25 indicating that Gilead Sciences is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Biogen
28 Very Positive mention(s)
2 Positive mention(s)
6 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Gilead Sciences
66 Very Positive mention(s)
4 Positive mention(s)
5 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Positive

Gilead Sciences has higher revenue and earnings than Biogen. Gilead Sciences is trading at a lower price-to-earnings ratio than Biogen, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Biogen$10.03B3.22$1.29B$5.6538.67
Gilead Sciences$30.46B5.93$8.51B-$2.67N/A

Summary

Gilead Sciences beats Biogen on 10 of the 17 factors compared between the two stocks.

How does Biogen compare to Ionis Pharmaceuticals?

Ionis Pharmaceuticals (NASDAQ:IONS) and Biogen (NASDAQ:BIIB) are both large-cap healthcare companies, but which is the superior business? We will compare the two businesses based on the strength of their analyst recommendations, institutional ownership, dividends, earnings, profitability, media sentiment, valuation and risk.

93.9% of Ionis Pharmaceuticals shares are held by institutional investors. Comparatively, 87.9% of Biogen shares are held by institutional investors. 1.8% of Ionis Pharmaceuticals shares are held by insiders. Comparatively, 0.3% of Biogen shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

Ionis Pharmaceuticals presently has a consensus target price of $94.15, indicating a potential upside of 54.22%. Biogen has a consensus target price of $227.79, indicating a potential upside of 4.25%. Given Ionis Pharmaceuticals' stronger consensus rating and higher probable upside, research analysts plainly believe Ionis Pharmaceuticals is more favorable than Biogen.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Ionis Pharmaceuticals
1 Sell rating(s)
4 Hold rating(s)
17 Buy rating(s)
0 Strong Buy rating(s)
2.73
Biogen
1 Sell rating(s)
13 Hold rating(s)
18 Buy rating(s)
1 Strong Buy rating(s)
2.58

In the previous week, Biogen had 20 more articles in the media than Ionis Pharmaceuticals. MarketBeat recorded 38 mentions for Biogen and 18 mentions for Ionis Pharmaceuticals. Ionis Pharmaceuticals' average media sentiment score of 1.32 beat Biogen's score of 1.25 indicating that Ionis Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Ionis Pharmaceuticals
14 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Biogen
28 Very Positive mention(s)
2 Positive mention(s)
6 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Biogen has a net margin of 8.32% compared to Ionis Pharmaceuticals' net margin of -64.76%. Biogen's return on equity of 11.18% beat Ionis Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Ionis Pharmaceuticals-64.76% -111.08% -17.41%
Biogen 8.32%11.18%6.88%

Biogen has higher revenue and earnings than Ionis Pharmaceuticals. Ionis Pharmaceuticals is trading at a lower price-to-earnings ratio than Biogen, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Ionis Pharmaceuticals$944M10.75-$381.39M-$3.46N/A
Biogen$10.03B3.22$1.29B$5.6538.67

Ionis Pharmaceuticals has a beta of 0.41, indicating that its share price is 59% less volatile than the broader market. Comparatively, Biogen has a beta of 0.17, indicating that its share price is 83% less volatile than the broader market.

Summary

Biogen beats Ionis Pharmaceuticals on 10 of the 17 factors compared between the two stocks.

How does Biogen compare to Moderna?

Moderna (NASDAQ:MRNA) and Biogen (NASDAQ:BIIB) are both large-cap healthcare companies, but which is the superior business? We will compare the two businesses based on the strength of their institutional ownership, risk, analyst recommendations, earnings, valuation, profitability, media sentiment and dividends.

Moderna presently has a consensus price target of $80.53, indicating a potential downside of 41.64%. Biogen has a consensus price target of $227.79, indicating a potential upside of 4.25%. Given Biogen's stronger consensus rating and higher possible upside, analysts plainly believe Biogen is more favorable than Moderna.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Moderna
3 Sell rating(s)
13 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.17
Biogen
1 Sell rating(s)
13 Hold rating(s)
18 Buy rating(s)
1 Strong Buy rating(s)
2.58

Biogen has higher revenue and earnings than Moderna. Moderna is trading at a lower price-to-earnings ratio than Biogen, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Moderna$1.94B28.34-$2.82B-$7.99N/A
Biogen$10.03B3.22$1.29B$5.6538.67

75.3% of Moderna shares are owned by institutional investors. Comparatively, 87.9% of Biogen shares are owned by institutional investors. 10.8% of Moderna shares are owned by insiders. Comparatively, 0.3% of Biogen shares are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

In the previous week, Moderna had 39 more articles in the media than Biogen. MarketBeat recorded 77 mentions for Moderna and 38 mentions for Biogen. Biogen's average media sentiment score of 1.25 beat Moderna's score of 0.42 indicating that Biogen is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Moderna
33 Very Positive mention(s)
15 Positive mention(s)
7 Neutral mention(s)
10 Negative mention(s)
10 Very Negative mention(s)
Neutral
Biogen
28 Very Positive mention(s)
2 Positive mention(s)
6 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Biogen has a net margin of 8.32% compared to Moderna's net margin of -141.43%. Biogen's return on equity of 11.18% beat Moderna's return on equity.

Company Net Margins Return on Equity Return on Assets
Moderna-141.43% -28.30% -19.39%
Biogen 8.32%11.18%6.88%

Moderna has a beta of 0.91, meaning that its stock price is 9% less volatile than the broader market. Comparatively, Biogen has a beta of 0.17, meaning that its stock price is 83% less volatile than the broader market.

Summary

Biogen beats Moderna on 13 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding BIIB and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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BIIB vs. The Competition

MetricBiogenBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$32.73B$4.02B$7.24B$12.93B
Dividend YieldN/A3.60%2.54%10.96%
P/E Ratio38.6711.56271.5025.38
Price / Sales3.221,345.95623.9296.47
Price / Cash9.79110.5979.2954.21
Price / Book1.7116.5012.956.14
Net Income$1.29B-$22.76M$3.46B$347.93M
7 Day Performance0.79%-0.23%-0.11%-0.78%
1 Month Performance4.33%11.93%8.32%5.60%
1 Year Performance65.25%55.61%24.70%15.64%

Biogen Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
BIIB
Biogen
3.5974 of 5 stars
$218.50
-1.4%
$227.79
+4.2%
+64.7%$32.73B$10.03B38.677,500
AMGN
Amgen
4.271 of 5 stars
$419.38
+1.0%
$372.39
-11.2%
+51.4%$226.73B$38.10B26.0631,500
DNLI
Denali Therapeutics
3.3958 of 5 stars
$24.35
-0.2%
$35.92
+47.5%
+53.4%$3.89B$330.53MN/A430
GILD
Gilead Sciences
4.1358 of 5 stars
$138.92
+0.4%
$158.04
+13.8%
+29.4%$172.25B$30.46BN/A17,000
IONS
Ionis Pharmaceuticals
3.7991 of 5 stars
$58.63
+2.4%
$94.65
+61.4%
+43.2%$9.74B$944MN/A1,402

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This page (NASDAQ:BIIB) was last updated on 8/29/2026 by MarketBeat.com Staff.
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