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Exelixis (EXEL) Competitors

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$55.92 +0.24 (+0.43%)
Closing price 07/17/2026 04:00 PM Eastern
Extended Trading
$55.80 -0.12 (-0.21%)
As of 07/17/2026 07:57 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

EXEL vs. ALNY, BIIB, INCY, UTHR, and NBIX

Should you buy Exelixis stock or one of its competitors? MarketBeat compares Exelixis with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Exelixis include Alnylam Pharmaceuticals (ALNY), Biogen (BIIB), Incyte (INCY), United Therapeutics (UTHR), and Neurocrine Biosciences (NBIX). These companies are all part of the "biotechnology" industry.

How does Exelixis compare to Alnylam Pharmaceuticals?

Exelixis (NASDAQ:EXEL) and Alnylam Pharmaceuticals (NASDAQ:ALNY) are both large-cap medical companies, but which is the better business? We will contrast the two companies based on the strength of their earnings, media sentiment, profitability, analyst recommendations, institutional ownership, dividends, valuation and risk.

85.3% of Exelixis shares are owned by institutional investors. Comparatively, 93.0% of Alnylam Pharmaceuticals shares are owned by institutional investors. 2.6% of Exelixis shares are owned by insiders. Comparatively, 0.9% of Alnylam Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

Exelixis has a net margin of 35.08% compared to Alnylam Pharmaceuticals' net margin of 11.72%. Alnylam Pharmaceuticals' return on equity of 85.76% beat Exelixis' return on equity.

Company Net Margins Return on Equity Return on Assets
Exelixis35.08% 39.89% 30.23%
Alnylam Pharmaceuticals 11.72%85.76%10.32%

Exelixis has a beta of 0.42, indicating that its share price is 58% less volatile than the broader market. Comparatively, Alnylam Pharmaceuticals has a beta of 0.27, indicating that its share price is 73% less volatile than the broader market.

Exelixis currently has a consensus price target of $48.80, indicating a potential downside of 12.73%. Alnylam Pharmaceuticals has a consensus price target of $455.31, indicating a potential upside of 70.23%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher possible upside, analysts clearly believe Alnylam Pharmaceuticals is more favorable than Exelixis.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Exelixis
2 Sell rating(s)
9 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.35
Alnylam Pharmaceuticals
0 Sell rating(s)
6 Hold rating(s)
18 Buy rating(s)
2 Strong Buy rating(s)
2.85

Exelixis has higher earnings, but lower revenue than Alnylam Pharmaceuticals. Exelixis is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Exelixis$2.32B6.06$782.57M$3.0118.58
Alnylam Pharmaceuticals$3.71B9.62$313.75M$3.6673.08

In the previous week, Alnylam Pharmaceuticals had 5 more articles in the media than Exelixis. MarketBeat recorded 15 mentions for Alnylam Pharmaceuticals and 10 mentions for Exelixis. Exelixis' average media sentiment score of 1.31 beat Alnylam Pharmaceuticals' score of 0.58 indicating that Exelixis is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Exelixis
8 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Alnylam Pharmaceuticals
4 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Alnylam Pharmaceuticals beats Exelixis on 11 of the 17 factors compared between the two stocks.

How does Exelixis compare to Biogen?

Biogen (NASDAQ:BIIB) and Exelixis (NASDAQ:EXEL) are both large-cap medical companies, but which is the superior business? We will compare the two companies based on the strength of their profitability, earnings, valuation, risk, dividends, analyst recommendations, institutional ownership and media sentiment.

87.9% of Biogen shares are held by institutional investors. Comparatively, 85.3% of Exelixis shares are held by institutional investors. 0.3% of Biogen shares are held by company insiders. Comparatively, 2.6% of Exelixis shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Biogen has higher revenue and earnings than Exelixis. Exelixis is trading at a lower price-to-earnings ratio than Biogen, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Biogen$9.89B3.07$1.29B$9.3222.10
Exelixis$2.32B6.06$782.57M$3.0118.58

Biogen has a beta of 0.16, meaning that its share price is 84% less volatile than the broader market. Comparatively, Exelixis has a beta of 0.42, meaning that its share price is 58% less volatile than the broader market.

Exelixis has a net margin of 35.08% compared to Biogen's net margin of 13.81%. Exelixis' return on equity of 39.89% beat Biogen's return on equity.

Company Net Margins Return on Equity Return on Assets
Biogen13.81% 12.83% 8.01%
Exelixis 35.08%39.89%30.23%

In the previous week, Biogen had 50 more articles in the media than Exelixis. MarketBeat recorded 60 mentions for Biogen and 10 mentions for Exelixis. Exelixis' average media sentiment score of 1.31 beat Biogen's score of 0.82 indicating that Exelixis is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Biogen
31 Very Positive mention(s)
7 Positive mention(s)
14 Neutral mention(s)
6 Negative mention(s)
1 Very Negative mention(s)
Positive
Exelixis
8 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Biogen presently has a consensus target price of $220.04, suggesting a potential upside of 6.82%. Exelixis has a consensus target price of $48.80, suggesting a potential downside of 12.73%. Given Biogen's stronger consensus rating and higher probable upside, equities analysts clearly believe Biogen is more favorable than Exelixis.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Biogen
2 Sell rating(s)
11 Hold rating(s)
17 Buy rating(s)
1 Strong Buy rating(s)
2.55
Exelixis
2 Sell rating(s)
9 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.35

Summary

Biogen beats Exelixis on 10 of the 17 factors compared between the two stocks.

How does Exelixis compare to Incyte?

Exelixis (NASDAQ:EXEL) and Incyte (NASDAQ:INCY) are both large-cap medical companies, but which is the better business? We will contrast the two businesses based on the strength of their institutional ownership, valuation, analyst recommendations, profitability, media sentiment, dividends, earnings and risk.

85.3% of Exelixis shares are owned by institutional investors. Comparatively, 97.0% of Incyte shares are owned by institutional investors. 2.6% of Exelixis shares are owned by insiders. Comparatively, 16.2% of Incyte shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

Exelixis has a net margin of 35.08% compared to Incyte's net margin of 26.71%. Exelixis' return on equity of 39.89% beat Incyte's return on equity.

Company Net Margins Return on Equity Return on Assets
Exelixis35.08% 39.89% 30.23%
Incyte 26.71%26.66%19.77%

Incyte has higher revenue and earnings than Exelixis. Incyte is trading at a lower price-to-earnings ratio than Exelixis, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Exelixis$2.32B6.06$782.57M$3.0118.58
Incyte$5.14B4.56$1.29B$7.0816.56

In the previous week, Incyte had 16 more articles in the media than Exelixis. MarketBeat recorded 26 mentions for Incyte and 10 mentions for Exelixis. Exelixis' average media sentiment score of 1.31 beat Incyte's score of 0.95 indicating that Exelixis is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Exelixis
8 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Incyte
14 Very Positive mention(s)
4 Positive mention(s)
7 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Exelixis presently has a consensus price target of $48.80, suggesting a potential downside of 12.73%. Incyte has a consensus price target of $109.95, suggesting a potential downside of 6.23%. Given Incyte's stronger consensus rating and higher possible upside, analysts clearly believe Incyte is more favorable than Exelixis.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Exelixis
2 Sell rating(s)
9 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.35
Incyte
0 Sell rating(s)
14 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.36

Exelixis has a beta of 0.42, indicating that its share price is 58% less volatile than the broader market. Comparatively, Incyte has a beta of 0.76, indicating that its share price is 24% less volatile than the broader market.

Summary

Incyte beats Exelixis on 9 of the 16 factors compared between the two stocks.

How does Exelixis compare to United Therapeutics?

United Therapeutics (NASDAQ:UTHR) and Exelixis (NASDAQ:EXEL) are both large-cap medical companies, but which is the superior stock? We will compare the two companies based on the strength of their earnings, dividends, profitability, analyst recommendations, valuation, risk, institutional ownership and media sentiment.

United Therapeutics has a beta of 0.58, suggesting that its share price is 42% less volatile than the broader market. Comparatively, Exelixis has a beta of 0.42, suggesting that its share price is 58% less volatile than the broader market.

United Therapeutics has a net margin of 40.62% compared to Exelixis' net margin of 35.08%. Exelixis' return on equity of 39.89% beat United Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
United Therapeutics40.62% 19.24% 17.25%
Exelixis 35.08%39.89%30.23%

United Therapeutics has higher revenue and earnings than Exelixis. Exelixis is trading at a lower price-to-earnings ratio than United Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
United Therapeutics$3.17B7.17$1.33B$27.0919.77
Exelixis$2.32B6.06$782.57M$3.0118.58

United Therapeutics currently has a consensus price target of $644.82, indicating a potential upside of 20.38%. Exelixis has a consensus price target of $48.80, indicating a potential downside of 12.73%. Given United Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe United Therapeutics is more favorable than Exelixis.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
United Therapeutics
0 Sell rating(s)
2 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.83
Exelixis
2 Sell rating(s)
9 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.35

94.1% of United Therapeutics shares are owned by institutional investors. Comparatively, 85.3% of Exelixis shares are owned by institutional investors. 8.6% of United Therapeutics shares are owned by company insiders. Comparatively, 2.6% of Exelixis shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

In the previous week, United Therapeutics had 10 more articles in the media than Exelixis. MarketBeat recorded 20 mentions for United Therapeutics and 10 mentions for Exelixis. Exelixis' average media sentiment score of 1.31 beat United Therapeutics' score of 1.03 indicating that Exelixis is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
United Therapeutics
15 Very Positive mention(s)
2 Positive mention(s)
0 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Exelixis
8 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

United Therapeutics beats Exelixis on 13 of the 16 factors compared between the two stocks.

How does Exelixis compare to Neurocrine Biosciences?

Neurocrine Biosciences (NASDAQ:NBIX) and Exelixis (NASDAQ:EXEL) are both large-cap medical companies, but which is the better business? We will compare the two businesses based on the strength of their institutional ownership, analyst recommendations, valuation, profitability, risk, dividends, media sentiment and earnings.

Neurocrine Biosciences currently has a consensus target price of $192.86, indicating a potential upside of 12.86%. Exelixis has a consensus target price of $48.80, indicating a potential downside of 12.73%. Given Neurocrine Biosciences' stronger consensus rating and higher probable upside, equities research analysts plainly believe Neurocrine Biosciences is more favorable than Exelixis.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Neurocrine Biosciences
0 Sell rating(s)
3 Hold rating(s)
18 Buy rating(s)
2 Strong Buy rating(s)
2.96
Exelixis
2 Sell rating(s)
9 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.35

Exelixis has a net margin of 35.08% compared to Neurocrine Biosciences' net margin of 21.55%. Exelixis' return on equity of 39.89% beat Neurocrine Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Neurocrine Biosciences21.55% 19.79% 13.82%
Exelixis 35.08%39.89%30.23%

In the previous week, Neurocrine Biosciences had 9 more articles in the media than Exelixis. MarketBeat recorded 19 mentions for Neurocrine Biosciences and 10 mentions for Exelixis. Exelixis' average media sentiment score of 1.31 beat Neurocrine Biosciences' score of 0.82 indicating that Exelixis is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Neurocrine Biosciences
8 Very Positive mention(s)
1 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Exelixis
8 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Exelixis has lower revenue, but higher earnings than Neurocrine Biosciences. Exelixis is trading at a lower price-to-earnings ratio than Neurocrine Biosciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Neurocrine Biosciences$2.86B6.01$478.60M$6.4926.33
Exelixis$2.32B6.06$782.57M$3.0118.58

Neurocrine Biosciences has a beta of 0.39, suggesting that its stock price is 61% less volatile than the broader market. Comparatively, Exelixis has a beta of 0.42, suggesting that its stock price is 58% less volatile than the broader market.

92.6% of Neurocrine Biosciences shares are owned by institutional investors. Comparatively, 85.3% of Exelixis shares are owned by institutional investors. 4.6% of Neurocrine Biosciences shares are owned by insiders. Comparatively, 2.6% of Exelixis shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

Summary

Neurocrine Biosciences beats Exelixis on 10 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding EXEL and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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EXEL vs. The Competition

MetricExelixisMED IndustryMedical SectorNASDAQ Exchange
Market Cap$14.00B$3.69B$6.89B$12.43B
Dividend YieldN/A2.16%2.67%8.84%
P/E Ratio18.5820.8527.1423.89
Price / Sales6.06304.44524.0291.05
Price / Cash18.39142.3351.4660.07
Price / Book6.948.2610.696.18
Net Income$782.57M$23.83M$3.59B$331.73M
7 Day Performance-1.03%-3.48%-2.17%-2.09%
1 Month Performance7.72%2.58%1.63%-2.19%
1 Year Performance25.75%45.93%25.56%17.20%

Exelixis Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
EXEL
Exelixis
3.6031 of 5 stars
$55.92
+0.4%
$48.80
-12.7%
+24.6%$14.00B$2.32B18.581,077
ALNY
Alnylam Pharmaceuticals
4.1479 of 5 stars
$281.26
-2.4%
$455.31
+61.9%
-17.6%$37.55B$4.29B76.852,770
BIIB
Biogen
3.5476 of 5 stars
$191.95
-8.2%
$220.04
+14.6%
+60.1%$28.34B$9.94B20.607,500
INCY
Incyte
2.8443 of 5 stars
$114.88
+0.6%
$109.95
-4.3%
+70.1%$22.95B$5.14B16.232,844
UTHR
United Therapeutics
4.5798 of 5 stars
$526.66
-1.7%
$644.82
+22.4%
+80.2%$22.36B$3.18B19.441,400

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This page (NASDAQ:EXEL) was last updated on 7/18/2026 by MarketBeat.com Staff.
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