Go Pro

Exelixis (EXEL) Competitors

Exelixis logo
$54.07 +1.87 (+3.58%)
Closing price 08/7/2026 04:00 PM Eastern
Extended Trading
$53.71 -0.36 (-0.67%)
As of 08/7/2026 07:34 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

EXEL vs. ARGX, RVMD, NTRA, BIIB, and ALNY

Should you buy Exelixis stock or one of its competitors? MarketBeat compares Exelixis with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Exelixis include argenex (ARGX), Revolution Medicines (RVMD), Natera (NTRA), Biogen (BIIB), and Alnylam Pharmaceuticals (ALNY). These companies are all part of the "biotechnology" industry.

How does Exelixis compare to argenex?

argenex (NASDAQ:ARGX) and Exelixis (NASDAQ:EXEL) are both large-cap healthcare companies, but which is the better business? We will contrast the two businesses based on the strength of their media sentiment, dividends, analyst recommendations, risk, valuation, profitability, institutional ownership and earnings.

In the previous week, Exelixis had 28 more articles in the media than argenex. MarketBeat recorded 39 mentions for Exelixis and 11 mentions for argenex. argenex's average media sentiment score of 0.96 beat Exelixis' score of 0.43 indicating that argenex is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
argenex
5 Very Positive mention(s)
1 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Exelixis
13 Very Positive mention(s)
1 Positive mention(s)
9 Neutral mention(s)
3 Negative mention(s)
1 Very Negative mention(s)
Neutral

argenex has a beta of 0.46, indicating that its stock price is 54% less volatile than the broader market. Comparatively, Exelixis has a beta of 0.44, indicating that its stock price is 56% less volatile than the broader market.

Exelixis has a net margin of 35.33% compared to argenex's net margin of 32.19%. argenex's return on equity of 43.59% beat Exelixis' return on equity.

Company Net Margins Return on Equity Return on Assets
argenex32.19% 43.59% 36.66%
Exelixis 35.33%42.17%31.76%

argenex presently has a consensus price target of $1,056.89, suggesting a potential upside of 22.18%. Exelixis has a consensus price target of $49.79, suggesting a potential downside of 7.92%. Given argenex's stronger consensus rating and higher probable upside, analysts clearly believe argenex is more favorable than Exelixis.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
argenex
0 Sell rating(s)
4 Hold rating(s)
18 Buy rating(s)
2 Strong Buy rating(s)
2.92
Exelixis
2 Sell rating(s)
10 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.26

argenex has higher revenue and earnings than Exelixis. Exelixis is trading at a lower price-to-earnings ratio than argenex, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
argenex$4.25B12.74$1.29B$26.0433.22
Exelixis$2.32B5.86$782.57M$3.0117.96

60.3% of argenex shares are owned by institutional investors. Comparatively, 85.3% of Exelixis shares are owned by institutional investors. 2.4% of argenex shares are owned by insiders. Comparatively, 2.6% of Exelixis shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

Summary

argenex beats Exelixis on 13 of the 17 factors compared between the two stocks.

How does Exelixis compare to Revolution Medicines?

Revolution Medicines (NASDAQ:RVMD) and Exelixis (NASDAQ:EXEL) are both large-cap healthcare companies, but which is the superior investment? We will contrast the two businesses based on the strength of their analyst recommendations, institutional ownership, profitability, valuation, dividends, earnings, risk and media sentiment.

Exelixis has higher revenue and earnings than Revolution Medicines. Revolution Medicines is trading at a lower price-to-earnings ratio than Exelixis, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Revolution Medicines$11.58M3,797.22-$1.13B-$7.07N/A
Exelixis$2.32B5.86$782.57M$3.0117.96

In the previous week, Exelixis had 17 more articles in the media than Revolution Medicines. MarketBeat recorded 39 mentions for Exelixis and 22 mentions for Revolution Medicines. Revolution Medicines' average media sentiment score of 0.82 beat Exelixis' score of 0.43 indicating that Revolution Medicines is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Revolution Medicines
13 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
2 Negative mention(s)
1 Very Negative mention(s)
Positive
Exelixis
13 Very Positive mention(s)
1 Positive mention(s)
9 Neutral mention(s)
3 Negative mention(s)
1 Very Negative mention(s)
Neutral

94.3% of Revolution Medicines shares are owned by institutional investors. Comparatively, 85.3% of Exelixis shares are owned by institutional investors. 7.6% of Revolution Medicines shares are owned by insiders. Comparatively, 2.6% of Exelixis shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

Revolution Medicines has a beta of 1.39, suggesting that its stock price is 39% more volatile than the broader market. Comparatively, Exelixis has a beta of 0.44, suggesting that its stock price is 56% less volatile than the broader market.

Exelixis has a net margin of 35.33% compared to Revolution Medicines' net margin of 0.00%. Exelixis' return on equity of 42.17% beat Revolution Medicines' return on equity.

Company Net Margins Return on Equity Return on Assets
Revolution MedicinesN/A -102.61% -70.72%
Exelixis 35.33%42.17%31.76%

Revolution Medicines currently has a consensus price target of $153.05, suggesting a potential downside of 25.39%. Exelixis has a consensus price target of $49.79, suggesting a potential downside of 7.92%. Given Exelixis' higher probable upside, analysts plainly believe Exelixis is more favorable than Revolution Medicines.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Revolution Medicines
1 Sell rating(s)
1 Hold rating(s)
18 Buy rating(s)
2 Strong Buy rating(s)
2.95
Exelixis
2 Sell rating(s)
10 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.26

Summary

Exelixis beats Revolution Medicines on 9 of the 17 factors compared between the two stocks.

How does Exelixis compare to Natera?

Natera (NASDAQ:NTRA) and Exelixis (NASDAQ:EXEL) are both large-cap healthcare companies, but which is the better business? We will compare the two companies based on the strength of their risk, valuation, analyst recommendations, institutional ownership, profitability, media sentiment, dividends and earnings.

Exelixis has higher revenue and earnings than Natera. Natera is trading at a lower price-to-earnings ratio than Exelixis, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Natera$2.31B20.00-$208.16M-$1.63N/A
Exelixis$2.32B5.86$782.57M$3.0117.96

Natera currently has a consensus target price of $299.65, indicating a potential downside of 6.97%. Exelixis has a consensus target price of $49.79, indicating a potential downside of 7.92%. Given Natera's stronger consensus rating and higher probable upside, equities research analysts clearly believe Natera is more favorable than Exelixis.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Natera
2 Sell rating(s)
3 Hold rating(s)
15 Buy rating(s)
2 Strong Buy rating(s)
2.77
Exelixis
2 Sell rating(s)
10 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.26

99.9% of Natera shares are owned by institutional investors. Comparatively, 85.3% of Exelixis shares are owned by institutional investors. 5.1% of Natera shares are owned by insiders. Comparatively, 2.6% of Exelixis shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

In the previous week, Exelixis had 2 more articles in the media than Natera. MarketBeat recorded 39 mentions for Exelixis and 37 mentions for Natera. Natera's average media sentiment score of 0.83 beat Exelixis' score of 0.43 indicating that Natera is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Natera
17 Very Positive mention(s)
4 Positive mention(s)
7 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Positive
Exelixis
13 Very Positive mention(s)
1 Positive mention(s)
9 Neutral mention(s)
3 Negative mention(s)
1 Very Negative mention(s)
Neutral

Natera has a beta of 1.51, meaning that its stock price is 51% more volatile than the broader market. Comparatively, Exelixis has a beta of 0.44, meaning that its stock price is 56% less volatile than the broader market.

Exelixis has a net margin of 35.33% compared to Natera's net margin of -7.11%. Exelixis' return on equity of 42.17% beat Natera's return on equity.

Company Net Margins Return on Equity Return on Assets
Natera-7.11% -11.82% -8.19%
Exelixis 35.33%42.17%31.76%

Summary

Natera beats Exelixis on 9 of the 17 factors compared between the two stocks.

How does Exelixis compare to Biogen?

Exelixis (NASDAQ:EXEL) and Biogen (NASDAQ:BIIB) are both large-cap healthcare companies, but which is the superior stock? We will contrast the two businesses based on the strength of their media sentiment, institutional ownership, profitability, dividends, valuation, earnings, risk and analyst recommendations.

85.3% of Exelixis shares are held by institutional investors. Comparatively, 87.9% of Biogen shares are held by institutional investors. 2.6% of Exelixis shares are held by company insiders. Comparatively, 0.3% of Biogen shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

In the previous week, Exelixis had 11 more articles in the media than Biogen. MarketBeat recorded 39 mentions for Exelixis and 28 mentions for Biogen. Biogen's average media sentiment score of 0.98 beat Exelixis' score of 0.43 indicating that Biogen is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Exelixis
13 Very Positive mention(s)
1 Positive mention(s)
9 Neutral mention(s)
3 Negative mention(s)
1 Very Negative mention(s)
Neutral
Biogen
18 Very Positive mention(s)
3 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Exelixis has a beta of 0.44, indicating that its share price is 56% less volatile than the broader market. Comparatively, Biogen has a beta of 0.17, indicating that its share price is 83% less volatile than the broader market.

Biogen has higher revenue and earnings than Exelixis. Exelixis is trading at a lower price-to-earnings ratio than Biogen, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Exelixis$2.32B5.86$782.57M$3.0117.96
Biogen$10.03B3.06$1.29B$5.6536.80

Exelixis currently has a consensus target price of $49.79, suggesting a potential downside of 7.92%. Biogen has a consensus target price of $224.61, suggesting a potential upside of 8.02%. Given Biogen's stronger consensus rating and higher probable upside, analysts clearly believe Biogen is more favorable than Exelixis.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Exelixis
2 Sell rating(s)
10 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.26
Biogen
1 Sell rating(s)
13 Hold rating(s)
17 Buy rating(s)
1 Strong Buy rating(s)
2.56

Exelixis has a net margin of 35.33% compared to Biogen's net margin of 8.32%. Exelixis' return on equity of 42.17% beat Biogen's return on equity.

Company Net Margins Return on Equity Return on Assets
Exelixis35.33% 42.17% 31.76%
Biogen 8.32%11.18%6.88%

Summary

Biogen beats Exelixis on 10 of the 17 factors compared between the two stocks.

How does Exelixis compare to Alnylam Pharmaceuticals?

Alnylam Pharmaceuticals (NASDAQ:ALNY) and Exelixis (NASDAQ:EXEL) are both large-cap healthcare companies, but which is the better investment? We will contrast the two companies based on the strength of their risk, analyst recommendations, dividends, valuation, profitability, earnings, institutional ownership and media sentiment.

93.0% of Alnylam Pharmaceuticals shares are owned by institutional investors. Comparatively, 85.3% of Exelixis shares are owned by institutional investors. 0.9% of Alnylam Pharmaceuticals shares are owned by insiders. Comparatively, 2.6% of Exelixis shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

Exelixis has a net margin of 35.33% compared to Alnylam Pharmaceuticals' net margin of 15.26%. Alnylam Pharmaceuticals' return on equity of 84.93% beat Exelixis' return on equity.

Company Net Margins Return on Equity Return on Assets
Alnylam Pharmaceuticals15.26% 84.93% 14.30%
Exelixis 35.33%42.17%31.76%

Alnylam Pharmaceuticals currently has a consensus price target of $396.72, indicating a potential upside of 80.98%. Exelixis has a consensus price target of $49.79, indicating a potential downside of 7.92%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher probable upside, analysts clearly believe Alnylam Pharmaceuticals is more favorable than Exelixis.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alnylam Pharmaceuticals
0 Sell rating(s)
5 Hold rating(s)
16 Buy rating(s)
3 Strong Buy rating(s)
2.92
Exelixis
2 Sell rating(s)
10 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.26

In the previous week, Exelixis had 1 more articles in the media than Alnylam Pharmaceuticals. MarketBeat recorded 39 mentions for Exelixis and 38 mentions for Alnylam Pharmaceuticals. Exelixis' average media sentiment score of 0.43 beat Alnylam Pharmaceuticals' score of -0.08 indicating that Exelixis is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Alnylam Pharmaceuticals
6 Very Positive mention(s)
4 Positive mention(s)
8 Neutral mention(s)
9 Negative mention(s)
0 Very Negative mention(s)
Neutral
Exelixis
13 Very Positive mention(s)
1 Positive mention(s)
9 Neutral mention(s)
3 Negative mention(s)
1 Very Negative mention(s)
Neutral

Alnylam Pharmaceuticals has a beta of 0.3, suggesting that its stock price is 70% less volatile than the broader market. Comparatively, Exelixis has a beta of 0.44, suggesting that its stock price is 56% less volatile than the broader market.

Exelixis has lower revenue, but higher earnings than Alnylam Pharmaceuticals. Exelixis is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alnylam Pharmaceuticals$4.80B6.11$313.75M$5.3840.74
Exelixis$2.32B5.86$782.57M$3.0117.96

Summary

Alnylam Pharmaceuticals beats Exelixis on 10 of the 17 factors compared between the two stocks.

Get Exelixis News Delivered to You Automatically

Sign up to receive the latest news and ratings for EXEL and its competitors with MarketBeat's FREE daily newsletter.

Subscribe Now
SMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy.

New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding EXEL and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
Skip Chart

Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
Skip Chart

EXEL vs. The Competition

MetricExelixisBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$13.12B$3.62B$6.94B$12.86B
Dividend YieldN/A3.77%2.59%10.09%
P/E Ratio17.008.94270.2625.05
Price / Sales5.861,271.39601.25100.65
Price / Cash17.2498.5871.4649.72
Price / Book7.3718.1013.256.21
Net Income$782.57M-$13.22M$3.45B$342.45M
7 Day Performance1.96%6.27%4.63%4.41%
1 Month Performance-3.64%-2.67%-0.81%-0.28%
1 Year Performance43.35%61.22%77.73%22.60%

Exelixis Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
EXEL
Exelixis
2.452 of 5 stars
$54.07
+3.6%
$49.79
-7.9%
+44.6%$13.12B$2.32B17.001,077
ARGX
argenex
4.5015 of 5 stars
$844.50
+1.7%
$1,056.89
+25.1%
+28.7%$52.83B$4.25B32.431,863
RVMD
Revolution Medicines
1.7655 of 5 stars
$193.46
+6.0%
$144.67
-25.2%
+487.0%$41.13B$11.58MN/A250
NTRA
Natera
2.9685 of 5 stars
$275.19
+1.8%
$267.83
-2.7%
+128.3%$39.41B$2.50BN/A6,140
BIIB
Biogen
3.8937 of 5 stars
$208.45
+3.3%
$224.61
+7.8%
+62.8%$30.80B$9.89B36.897,500

Related Companies and Tools


This page (NASDAQ:EXEL) was last updated on 8/8/2026 by MarketBeat.com Staff.
From Our Partners