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Exelixis (EXEL) Competitors

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$54.77 +1.54 (+2.89%)
Closing price 06/26/2026 04:00 PM Eastern
Extended Trading
$54.90 +0.13 (+0.24%)
As of 06/26/2026 06:31 PM Eastern
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EXEL vs. ALNY, BIIB, UTHR, INCY, and NBIX

Should you buy Exelixis stock or one of its competitors? MarketBeat compares Exelixis with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Exelixis include Alnylam Pharmaceuticals (ALNY), Biogen (BIIB), United Therapeutics (UTHR), Incyte (INCY), and Neurocrine Biosciences (NBIX). These companies are all part of the "biotechnology" industry.

How does Exelixis compare to Alnylam Pharmaceuticals?

Alnylam Pharmaceuticals (NASDAQ:ALNY) and Exelixis (NASDAQ:EXEL) are both large-cap medical companies, but which is the superior investment? We will contrast the two businesses based on the strength of their earnings, profitability, analyst recommendations, valuation, institutional ownership, media sentiment, dividends and risk.

Exelixis has a net margin of 35.08% compared to Alnylam Pharmaceuticals' net margin of 11.72%. Alnylam Pharmaceuticals' return on equity of 85.76% beat Exelixis' return on equity.

Company Net Margins Return on Equity Return on Assets
Alnylam Pharmaceuticals11.72% 85.76% 10.32%
Exelixis 35.08%39.89%30.23%

Alnylam Pharmaceuticals currently has a consensus price target of $463.13, suggesting a potential upside of 58.95%. Exelixis has a consensus price target of $46.87, suggesting a potential downside of 14.43%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher possible upside, research analysts clearly believe Alnylam Pharmaceuticals is more favorable than Exelixis.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alnylam Pharmaceuticals
0 Sell rating(s)
6 Hold rating(s)
18 Buy rating(s)
2 Strong Buy rating(s)
2.85
Exelixis
2 Sell rating(s)
10 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.30

In the previous week, Alnylam Pharmaceuticals had 12 more articles in the media than Exelixis. MarketBeat recorded 21 mentions for Alnylam Pharmaceuticals and 9 mentions for Exelixis. Alnylam Pharmaceuticals' average media sentiment score of 0.92 beat Exelixis' score of 0.59 indicating that Alnylam Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Alnylam Pharmaceuticals
12 Very Positive mention(s)
2 Positive mention(s)
4 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Positive
Exelixis
2 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
1 Very Negative mention(s)
Positive

Exelixis has lower revenue, but higher earnings than Alnylam Pharmaceuticals. Exelixis is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alnylam Pharmaceuticals$3.71B10.47$313.75M$3.6679.61
Exelixis$2.38B5.80$782.57M$3.0118.20

93.0% of Alnylam Pharmaceuticals shares are owned by institutional investors. Comparatively, 85.3% of Exelixis shares are owned by institutional investors. 0.9% of Alnylam Pharmaceuticals shares are owned by company insiders. Comparatively, 2.6% of Exelixis shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

Alnylam Pharmaceuticals has a beta of 0.29, suggesting that its stock price is 71% less volatile than the broader market. Comparatively, Exelixis has a beta of 0.41, suggesting that its stock price is 59% less volatile than the broader market.

Summary

Alnylam Pharmaceuticals beats Exelixis on 12 of the 17 factors compared between the two stocks.

How does Exelixis compare to Biogen?

Exelixis (NASDAQ:EXEL) and Biogen (NASDAQ:BIIB) are both large-cap medical companies, but which is the superior business? We will compare the two businesses based on the strength of their institutional ownership, earnings, risk, profitability, analyst recommendations, dividends, media sentiment and valuation.

Biogen has higher revenue and earnings than Exelixis. Exelixis is trading at a lower price-to-earnings ratio than Biogen, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Exelixis$2.38B5.80$782.57M$3.0118.20
Biogen$9.89B3.22$1.29B$9.3223.18

Exelixis currently has a consensus target price of $46.87, indicating a potential downside of 14.43%. Biogen has a consensus target price of $217.37, indicating a potential upside of 0.62%. Given Biogen's stronger consensus rating and higher probable upside, analysts clearly believe Biogen is more favorable than Exelixis.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Exelixis
2 Sell rating(s)
10 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.30
Biogen
1 Sell rating(s)
12 Hold rating(s)
16 Buy rating(s)
1 Strong Buy rating(s)
2.57

Exelixis has a net margin of 35.08% compared to Biogen's net margin of 13.81%. Exelixis' return on equity of 39.89% beat Biogen's return on equity.

Company Net Margins Return on Equity Return on Assets
Exelixis35.08% 39.89% 30.23%
Biogen 13.81%12.83%8.01%

In the previous week, Biogen had 2 more articles in the media than Exelixis. MarketBeat recorded 11 mentions for Biogen and 9 mentions for Exelixis. Biogen's average media sentiment score of 0.78 beat Exelixis' score of 0.59 indicating that Biogen is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Exelixis
2 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
1 Very Negative mention(s)
Positive
Biogen
4 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Positive

Exelixis has a beta of 0.41, indicating that its stock price is 59% less volatile than the broader market. Comparatively, Biogen has a beta of 0.2, indicating that its stock price is 80% less volatile than the broader market.

85.3% of Exelixis shares are owned by institutional investors. Comparatively, 87.9% of Biogen shares are owned by institutional investors. 2.6% of Exelixis shares are owned by company insiders. Comparatively, 0.3% of Biogen shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company is poised for long-term growth.

Summary

Biogen beats Exelixis on 11 of the 17 factors compared between the two stocks.

How does Exelixis compare to United Therapeutics?

Exelixis (NASDAQ:EXEL) and United Therapeutics (NASDAQ:UTHR) are both large-cap medical companies, but which is the better business? We will contrast the two businesses based on the strength of their media sentiment, institutional ownership, analyst recommendations, dividends, earnings, profitability, risk and valuation.

United Therapeutics has a net margin of 40.62% compared to Exelixis' net margin of 35.08%. Exelixis' return on equity of 39.89% beat United Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Exelixis35.08% 39.89% 30.23%
United Therapeutics 40.62%19.24%17.25%

United Therapeutics has higher revenue and earnings than Exelixis. Exelixis is trading at a lower price-to-earnings ratio than United Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Exelixis$2.38B5.80$782.57M$3.0118.20
United Therapeutics$3.18B7.24$1.33B$27.0920.03

Exelixis has a beta of 0.41, suggesting that its share price is 59% less volatile than the broader market. Comparatively, United Therapeutics has a beta of 0.57, suggesting that its share price is 43% less volatile than the broader market.

85.3% of Exelixis shares are held by institutional investors. Comparatively, 94.1% of United Therapeutics shares are held by institutional investors. 2.6% of Exelixis shares are held by insiders. Comparatively, 8.6% of United Therapeutics shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

In the previous week, United Therapeutics had 8 more articles in the media than Exelixis. MarketBeat recorded 17 mentions for United Therapeutics and 9 mentions for Exelixis. United Therapeutics' average media sentiment score of 0.80 beat Exelixis' score of 0.59 indicating that United Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Exelixis
2 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
1 Very Negative mention(s)
Positive
United Therapeutics
11 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Exelixis currently has a consensus price target of $46.87, suggesting a potential downside of 14.43%. United Therapeutics has a consensus price target of $619.42, suggesting a potential upside of 14.14%. Given United Therapeutics' stronger consensus rating and higher probable upside, analysts plainly believe United Therapeutics is more favorable than Exelixis.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Exelixis
2 Sell rating(s)
10 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.30
United Therapeutics
0 Sell rating(s)
2 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.85

Summary

United Therapeutics beats Exelixis on 14 of the 16 factors compared between the two stocks.

How does Exelixis compare to Incyte?

Incyte (NASDAQ:INCY) and Exelixis (NASDAQ:EXEL) are both large-cap medical companies, but which is the better stock? We will compare the two companies based on the strength of their valuation, earnings, analyst recommendations, media sentiment, institutional ownership, dividends, risk and profitability.

Exelixis has a net margin of 35.08% compared to Incyte's net margin of 26.71%. Exelixis' return on equity of 39.89% beat Incyte's return on equity.

Company Net Margins Return on Equity Return on Assets
Incyte26.71% 26.66% 19.77%
Exelixis 35.08%39.89%30.23%

Incyte has a beta of 0.79, meaning that its stock price is 21% less volatile than the broader market. Comparatively, Exelixis has a beta of 0.41, meaning that its stock price is 59% less volatile than the broader market.

Incyte has higher revenue and earnings than Exelixis. Incyte is trading at a lower price-to-earnings ratio than Exelixis, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Incyte$5.14B4.42$1.29B$7.0816.07
Exelixis$2.38B5.80$782.57M$3.0118.20

In the previous week, Incyte had 8 more articles in the media than Exelixis. MarketBeat recorded 17 mentions for Incyte and 9 mentions for Exelixis. Incyte's average media sentiment score of 0.69 beat Exelixis' score of 0.59 indicating that Incyte is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Incyte
6 Very Positive mention(s)
2 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Exelixis
2 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
1 Very Negative mention(s)
Positive

97.0% of Incyte shares are held by institutional investors. Comparatively, 85.3% of Exelixis shares are held by institutional investors. 16.2% of Incyte shares are held by company insiders. Comparatively, 2.6% of Exelixis shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Incyte presently has a consensus target price of $107.85, suggesting a potential downside of 5.19%. Exelixis has a consensus target price of $46.87, suggesting a potential downside of 14.43%. Given Incyte's stronger consensus rating and higher possible upside, equities research analysts plainly believe Incyte is more favorable than Exelixis.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Incyte
0 Sell rating(s)
14 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.36
Exelixis
2 Sell rating(s)
10 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.30

Summary

Incyte beats Exelixis on 10 of the 15 factors compared between the two stocks.

How does Exelixis compare to Neurocrine Biosciences?

Exelixis (NASDAQ:EXEL) and Neurocrine Biosciences (NASDAQ:NBIX) are both large-cap medical companies, but which is the better stock? We will contrast the two companies based on the strength of their media sentiment, institutional ownership, analyst recommendations, valuation, profitability, earnings, dividends and risk.

Exelixis has higher earnings, but lower revenue than Neurocrine Biosciences. Exelixis is trading at a lower price-to-earnings ratio than Neurocrine Biosciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Exelixis$2.38B5.80$782.57M$3.0118.20
Neurocrine Biosciences$2.86B5.92$478.60M$6.4925.97

In the previous week, Exelixis had 3 more articles in the media than Neurocrine Biosciences. MarketBeat recorded 9 mentions for Exelixis and 6 mentions for Neurocrine Biosciences. Neurocrine Biosciences' average media sentiment score of 1.27 beat Exelixis' score of 0.59 indicating that Neurocrine Biosciences is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Exelixis
2 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
1 Very Negative mention(s)
Positive
Neurocrine Biosciences
3 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

85.3% of Exelixis shares are owned by institutional investors. Comparatively, 92.6% of Neurocrine Biosciences shares are owned by institutional investors. 2.6% of Exelixis shares are owned by insiders. Comparatively, 4.6% of Neurocrine Biosciences shares are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

Exelixis has a beta of 0.41, suggesting that its stock price is 59% less volatile than the broader market. Comparatively, Neurocrine Biosciences has a beta of 0.4, suggesting that its stock price is 60% less volatile than the broader market.

Exelixis presently has a consensus price target of $46.87, indicating a potential downside of 14.43%. Neurocrine Biosciences has a consensus price target of $187.52, indicating a potential upside of 11.28%. Given Neurocrine Biosciences' stronger consensus rating and higher probable upside, analysts clearly believe Neurocrine Biosciences is more favorable than Exelixis.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Exelixis
2 Sell rating(s)
10 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.30
Neurocrine Biosciences
0 Sell rating(s)
3 Hold rating(s)
18 Buy rating(s)
2 Strong Buy rating(s)
2.96

Exelixis has a net margin of 35.08% compared to Neurocrine Biosciences' net margin of 21.55%. Exelixis' return on equity of 39.89% beat Neurocrine Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Exelixis35.08% 39.89% 30.23%
Neurocrine Biosciences 21.55%19.79%13.82%

Summary

Neurocrine Biosciences beats Exelixis on 11 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding EXEL and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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EXEL vs. The Competition

MetricExelixisMED IndustryMedical SectorNASDAQ Exchange
Market Cap$13.38B$3.55B$6.70B$12.22B
Dividend YieldN/A2.25%2.67%6.13%
P/E Ratio18.2021.5625.8224.18
Price / Sales5.80334.04576.05114.38
Price / Cash17.58137.3846.9954.37
Price / Book6.808.3410.776.36
Net Income$782.57M$23.91M$3.58B$337.99M
7 Day Performance5.51%3.42%2.20%0.10%
1 Month Performance9.47%1.55%1.11%-0.11%
1 Year Performance25.42%65.22%34.26%27.60%

Exelixis Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
EXEL
Exelixis
2.233 of 5 stars
$54.77
+2.9%
$46.87
-14.4%
+27.1%$13.38B$2.38B18.201,077
ALNY
Alnylam Pharmaceuticals
4.1613 of 5 stars
$281.90
-2.1%
$463.13
+64.3%
-8.4%$37.64B$4.29B77.022,770
BIIB
Biogen
3.0402 of 5 stars
$195.52
-1.6%
$216.70
+10.8%
+70.2%$28.87B$9.94B20.987,500
UTHR
United Therapeutics
4.4937 of 5 stars
$548.27
-0.2%
$619.42
+13.0%
+91.0%$23.27B$3.18B20.241,400
INCY
Incyte
3.6217 of 5 stars
$99.75
-2.2%
$105.10
+5.4%
+60.6%$19.93B$5.14B14.092,844

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This page (NASDAQ:EXEL) was last updated on 6/27/2026 by MarketBeat.com Staff.
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