| 5/19/2025 | Jane Street Group LLC | 138,552 | $521K | 0.0% | +216.8% | 0.203% | |
| 5/16/2025 | Woodline Partners LP | 1,477,907 | $5.56M | 0.0% | +8.9% | 2.162% | |
| 5/16/2025 | Goldman Sachs Group Inc. | 741,329 | $2.79M | 0.0% | +93.6% | 1.084% | |
| 5/16/2025 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 23,932 | $90K | 0.0% | -8.7% | 0.035% | |
| 5/16/2025 | BVF Inc. IL | 5,295,893 | $19.91M | 0.8% | -7.3% | 7.747% | |
| 5/16/2025 | Bain Capital Life Sciences Investors LLC | 6,843,954 | $25.73M | 3.8% | -8.4% | 10.011% | |
| 5/16/2025 | AQR Capital Management LLC | 45,661 | $172K | 0.0% | N/A | 0.067% | |
| 5/15/2025 | MPM Bioimpact LLC | 2,930,446 | $11.02M | 1.9% | +0.6% | 4.287% | |
| 5/15/2025 | PDT Partners LLC | 74,299 | $279K | 0.0% | N/A | 0.109% | |
| 5/15/2025 | Cubist Systematic Strategies LLC | 93,669 | $352K | 0.0% | +260.4% | 0.137% | |
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| 5/15/2025 | Alpine Global Management LLC | 13,874 | $52K | 0.0% | N/A | 0.020% | |
| 5/15/2025 | Quarry LP | 12,000 | $45K | 0.0% | N/A | 0.018% | |
| 5/15/2025 | Paradigm Biocapital Advisors LP | 6,741,172 | $25.35M | 1.2% | -7.7% | 9.861% | |
| 5/14/2025 | Affinity Asset Advisors LLC | 325,000 | $1.22M | 0.1% | N/A | 0.475% | |
| 5/14/2025 | MetLife Investment Management LLC | 17,675 | $66K | 0.0% | -25.4% | 0.026% | |
| 5/14/2025 | Walleye Capital LLC | 87,705 | $330K | 0.0% | +30.9% | 0.128% | |
| 5/14/2025 | Portland Investment Counsel Inc. | 50,000 | $188K | 0.1% | +100.0% | 0.073% | |
| 5/14/2025 | Candriam S.C.A. | 850,517 | $3.20M | 0.0% | -45.2% | 1.244% | |
| 5/14/2025 | Hsbc Holdings PLC | 15,698 | $58K | 0.0% | +56.9% | 0.023% | |
| 5/14/2025 | Wellington Management Group LLP | 1,473,679 | $5.54M | 0.0% | -3.4% | 2.156% | |
| 5/13/2025 | Brooklyn Investment Group | 18,915 | $71K | 0.0% | N/A | 0.028% | |
| 5/13/2025 | Persistent Asset Partners Ltd | 22,988 | $86K | 0.1% | N/A | 0.034% | |
| 5/12/2025 | Nuveen LLC | 344,296 | $1.30M | 0.0% | N/A | 0.504% | |
| 5/12/2025 | Invesco Ltd. | 50,810 | $191K | 0.0% | +208.9% | 0.074% | |
| 5/9/2025 | Deutsche Bank AG | 54,329 | $204K | 0.0% | +38.1% | 0.079% | |
| 5/9/2025 | Charles Schwab Investment Management Inc. | 349,023 | $1.31M | 0.0% | +4.8% | 0.511% | |
| 5/7/2025 | Corton Capital Inc. | 21,741 | $82K | 0.3% | +25.6% | 0.032% | |
| 5/6/2025 | Y Intercept Hong Kong Ltd | 10,882 | $41K | 0.0% | -42.7% | 0.016% | |
| 4/30/2025 | Alps Advisors Inc. | 50,484 | $190K | 0.0% | +9.0% | 0.074% | |
| 4/30/2025 | China Universal Asset Management Co. Ltd. | 14,892 | $56K | 0.0% | +22.6% | 0.022% | |
| 4/29/2025 | Bank of New York Mellon Corp | 131,994 | $496K | 0.0% | +2.6% | 0.193% | |
| 4/10/2025 | Hennion & Walsh Asset Management Inc. | 242,486 | $912K | 0.0% | +14.2% | 0.355% | |
| 3/24/2025 | Wellington Management Group LLP | 1,525,484 | $8.84M | 0.0% | +52.1% | 2.662% | |
| 2/25/2025 | Polar Asset Management Partners Inc. | 20,400 | $119K | 0.0% | N/A | 0.036% | |
| 2/17/2025 | UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 93,979 | $548K | 0.0% | +23.7% | 0.164% | |
| 2/17/2025 | Woodline Partners LP | 1,357,479 | $7.91M | 0.1% | +0.2% | 2.369% | |
| 2/17/2025 | Squarepoint Ops LLC | 48,829 | $285K | 0.0% | +205.8% | 0.085% | |
| 2/17/2025 | Two Sigma Investments LP | 72,877 | $425K | 0.0% | -27.2% | 0.127% | |
| 2/17/2025 | Two Sigma Advisers LP | 89,000 | $519K | 0.0% | -12.1% | 0.155% | |
| 2/17/2025 | Rafferty Asset Management LLC | 81,424 | $475K | 0.0% | -10.0% | 0.142% | |
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| 2/17/2025 | Point72 Asset Management L.P. | 3,670,826 | $21.40M | 0.0% | -0.4% | 6.406% | |
| 2/17/2025 | Polar Asset Management Partners Inc. | 20,400 | $119K | 0.0% | N/A | 0.036% | |
| 2/17/2025 | ProShare Advisors LLC | 14,226 | $83K | 0.0% | +30.2% | 0.025% | |
| 2/17/2025 | MPM Bioimpact LLC | 2,912,550 | $16.98M | 2.4% | +8.7% | 5.083% | |
| 2/17/2025 | Paradigm Biocapital Advisors LP | 7,304,970 | $42.59M | 1.5% | +32.7% | 12.749% | |
| 2/17/2025 | Millennium Management LLC | 979,219 | $5.71M | 0.0% | +1,154.4% | 1.709% | |
| 2/17/2025 | Lightspeed Management Company L.L.C. | 1,930,894 | $11.26M | 3.1% | N/A | 3.370% | |
| 2/17/2025 | J. Goldman & Co LP | 13,500 | $79K | 0.0% | -60.0% | 0.024% | |
| 2/17/2025 | Deutsche Bank AG | 39,331 | $229K | 0.0% | +45.0% | 0.069% | |
| 2/17/2025 | D. E. Shaw & Co. Inc. | 12,445 | $73K | 0.0% | -51.4% | 0.022% | |
| 2/17/2025 | Driehaus Capital Management LLC | 220,264 | $1.28M | 0.0% | N/A | 0.384% | |
| 2/17/2025 | Deep Track Capital LP | 3,442,833 | $20.07M | 0.7% | -13.9% | 6.008% | |
| 2/17/2025 | Cubist Systematic Strategies LLC | 25,987 | $152K | 0.0% | N/A | 0.045% | |
| 2/17/2025 | BVF Inc. IL | 5,715,893 | $33.32M | 1.1% | -37.4% | 9.975% | |
| 2/17/2025 | Balyasny Asset Management L.P. | 1,127,589 | $6.57M | 0.0% | +59.0% | 1.968% | |
| 2/17/2025 | Bank of America Corp DE | 865,339 | $5.05M | 0.0% | +110.6% | 1.510% | |
| 2/17/2025 | BNP Paribas Financial Markets | 193,748 | $1.13M | 0.0% | N/A | 0.338% | |
| 2/17/2025 | Ameriprise Financial Inc. | 449,698 | $2.62M | 0.0% | -2.9% | 0.785% | |
| 2/14/2025 | Boxer Capital Management LLC | 650,000 | $3.79M | 0.3% | N/A | 1.134% | |
| 2/14/2025 | Jane Street Group LLC | 43,737 | $255K | 0.0% | -44.7% | 0.076% | |
| 2/14/2025 | Schonfeld Strategic Advisors LLC | 505,400 | $2.95M | 0.0% | +9.4% | 0.882% | |
| 2/14/2025 | Northern Trust Corp | 423,787 | $2.47M | 0.0% | +8.7% | 0.740% | |
| 2/14/2025 | Aquatic Capital Management LLC | 31,565 | $184K | 0.0% | N/A | 0.055% | |
| 2/14/2025 | Boothbay Fund Management LLC | 31,226 | $182K | 0.0% | +10.8% | 0.054% | |
| 2/14/2025 | Susquehanna Fundamental Investments LLC | 10,976 | $64K | 0.0% | N/A | 0.019% | |
| 2/14/2025 | Virtus ETF Advisers LLC | 10,579 | $62K | 0.0% | +43.1% | 0.018% | |
| 2/14/2025 | Voya Investment Management LLC | 12,523 | $73K | 0.0% | -76.0% | 0.022% | |
| 2/14/2025 | Adage Capital Partners GP L.L.C. | 365,198 | $2.13M | 0.0% | -8.7% | 0.637% | |
| 2/14/2025 | Syon Capital LLC | 13,151 | $77K | 0.0% | N/A | 0.023% | |
| 2/14/2025 | Price T Rowe Associates Inc. MD | 26,112 | $153K | 0.0% | -17.0% | 0.046% | |
| 2/14/2025 | Silverarc Capital Management LLC | 233,281 | $1.36M | 0.3% | -48.7% | 0.407% | |
| 2/14/2025 | Hsbc Holdings PLC | 10,005 | $58K | 0.0% | N/A | 0.017% | |
| 2/14/2025 | Avoro Capital Advisors LLC | 1,651,982 | $9.63M | 0.1% | N/A | 2.883% | |
| 2/14/2025 | Bain Capital Life Sciences Investors LLC | 7,470,214 | $43.55M | 5.1% | N/A | 13.037% | |
| 2/14/2025 | Tower Research Capital LLC TRC | 22,714 | $132K | 0.0% | +1,436.8% | 0.040% | |
| 2/14/2025 | Dimensional Fund Advisors LP | 1,332,792 | $7.77M | 0.0% | -3.2% | 2.326% | |
| 2/13/2025 | Marshall Wace LLP | 192,943 | $1.13M | 0.0% | -19.7% | 0.337% | |
| 2/13/2025 | Walleye Capital LLC | 67,007 | $391K | 0.0% | N/A | 0.117% | |
| 2/13/2025 | XTX Topco Ltd | 48,032 | $280K | 0.0% | +89.6% | 0.084% | |
| 2/13/2025 | Barclays PLC | 114,879 | $669K | 0.0% | +21.0% | 0.200% | |
| 2/13/2025 | Renaissance Technologies LLC | 157,300 | $917K | 0.0% | +435.0% | 0.275% | |
| 2/13/2025 | Legal & General Group Plc | 29,716 | $173K | 0.0% | -8.5% | 0.052% | |
| 2/13/2025 | Aristides Capital LLC | 32,500 | $189K | 0.0% | N/A | 0.057% | |
| 2/13/2025 | Wells Fargo & Company MN | 22,725 | $132K | 0.0% | +35.5% | 0.040% | |
| 2/12/2025 | ExodusPoint Capital Management LP | 91,298 | $532K | 0.0% | +30.7% | 0.159% | |
| 2/12/2025 | Geode Capital Management LLC | 926,162 | $5.40M | 0.0% | -0.9% | 1.616% | |
| 2/12/2025 | Franklin Resources Inc. | 273,706 | $1.60M | 0.0% | +1,714.9% | 0.478% | |
| 2/12/2025 | Alliancebernstein L.P. | 313,982 | $1.83M | 0.0% | +77.7% | 0.548% | |
| 2/12/2025 | Wellington Management Group LLP | 1,525,484 | $8.84M | 0.0% | +52.1% | 2.662% | |
| 2/12/2025 | Schroder Investment Management Group | 533,111 | $2.99M | 0.0% | +548.7% | 0.930% | |
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| 2/12/2025 | Pictet Asset Management Holding SA | 1,883,354 | $10.98M | 0.0% | +12.9% | 3.287% | |
| 2/12/2025 | JPMorgan Chase & Co. | 160,751 | $937K | 0.0% | -11.2% | 0.281% | |
| 2/11/2025 | Pier Capital LLC | 272,372 | $1.59M | 0.2% | N/A | 0.475% | |
| 2/11/2025 | EntryPoint Capital LLC | 69,526 | $405K | 0.2% | +101.3% | 0.121% | |
| 2/11/2025 | Vanguard Group Inc. | 2,685,009 | $15.65M | 0.0% | +6.0% | 4.686% | |
| 2/11/2025 | Fox Run Management L.L.C. | 13,769 | $80K | 0.0% | N/A | 0.024% | |
| 2/11/2025 | KLP Kapitalforvaltning AS | 5,100 | $30K | 0.0% | N/A | 0.009% | |
| 2/11/2025 | American Century Companies Inc. | 11,738 | $68K | 0.0% | -59.6% | 0.020% | |
| 2/11/2025 | Teacher Retirement System of Texas | 10,352 | $60K | 0.0% | N/A | 0.018% | |
| 2/10/2025 | Monaco Asset Management SAM | 25,000 | $146K | 0.0% | N/A | 0.044% | |
