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Olema Pharmaceuticals (OLMA) Competitors

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$10.22 -0.47 (-4.40%)
Closing price 09/11/2026 04:00 PM Eastern
Extended Trading
$8.82 -1.40 (-13.69%)
As of 09/11/2026 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

OLMA vs. AMLX, RCUS, DYN, GRAL, and DNLI

Should you buy Olema Pharmaceuticals stock or one of its competitors? Olema Pharmaceuticals's main competitors and comparable companies include Amylyx Pharmaceuticals (AMLX), Arcus Biosciences (RCUS), Dyne Therapeutics (DYN), GRAIL (GRAL), and Denali Therapeutics (DNLI). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Olema Pharmaceuticals compare to Amylyx Pharmaceuticals?

Olema Pharmaceuticals (NASDAQ:OLMA) and Amylyx Pharmaceuticals (NASDAQ:AMLX) are both healthcare companies, but which is the better business? We will compare the two companies based on the strength of their profitability, risk, institutional ownership, media sentiment, earnings, valuation, dividends and analyst recommendations.

91.8% of Olema Pharmaceuticals shares are held by institutional investors. Comparatively, 95.8% of Amylyx Pharmaceuticals shares are held by institutional investors. 12.6% of Olema Pharmaceuticals shares are held by company insiders. Comparatively, 10.9% of Amylyx Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

Olema Pharmaceuticals currently has a consensus price target of $42.40, suggesting a potential upside of 314.87%. Amylyx Pharmaceuticals has a consensus price target of $36.50, suggesting a potential upside of 15.43%. Given Olema Pharmaceuticals' higher probable upside, equities research analysts plainly believe Olema Pharmaceuticals is more favorable than Amylyx Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Olema Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.77
Amylyx Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
2 Strong Buy rating(s)
3.00

Olema Pharmaceuticals' return on equity of -48.26% beat Amylyx Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Olema PharmaceuticalsN/A -48.26% -43.04%
Amylyx Pharmaceuticals N/A -52.92%-48.53%

Amylyx Pharmaceuticals is trading at a lower price-to-earnings ratio than Olema Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Olema PharmaceuticalsN/AN/A-$162.45M-$2.12N/A
Amylyx PharmaceuticalsN/AN/A-$144.74M-$1.43N/A

In the previous week, Olema Pharmaceuticals had 4 more articles in the media than Amylyx Pharmaceuticals. MarketBeat recorded 10 mentions for Olema Pharmaceuticals and 6 mentions for Amylyx Pharmaceuticals. Amylyx Pharmaceuticals' average media sentiment score of 1.50 beat Olema Pharmaceuticals' score of 1.07 indicating that Amylyx Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Olema Pharmaceuticals
4 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Amylyx Pharmaceuticals
4 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Olema Pharmaceuticals has a beta of 1.98, suggesting that its share price is 98% more volatile than the broader market. Comparatively, Amylyx Pharmaceuticals has a beta of -0.13, suggesting that its share price is 113% less volatile than the broader market.

Summary

Olema Pharmaceuticals beats Amylyx Pharmaceuticals on 8 of the 14 factors compared between the two stocks.

How does Olema Pharmaceuticals compare to Arcus Biosciences?

Arcus Biosciences (NYSE:RCUS) and Olema Pharmaceuticals (NASDAQ:OLMA) are both healthcare companies, but which is the better business? We will contrast the two companies based on the strength of their earnings, valuation, institutional ownership, media sentiment, risk, profitability, dividends and analyst recommendations.

92.9% of Arcus Biosciences shares are owned by institutional investors. Comparatively, 91.8% of Olema Pharmaceuticals shares are owned by institutional investors. 7.6% of Arcus Biosciences shares are owned by insiders. Comparatively, 12.6% of Olema Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

Olema Pharmaceuticals has a net margin of 0.00% compared to Arcus Biosciences' net margin of -393.16%. Olema Pharmaceuticals' return on equity of -48.26% beat Arcus Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Arcus Biosciences-393.16% -89.54% -45.61%
Olema Pharmaceuticals N/A -48.26%-43.04%

Olema Pharmaceuticals has lower revenue, but higher earnings than Arcus Biosciences. Arcus Biosciences is trading at a lower price-to-earnings ratio than Olema Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Arcus Biosciences$247M12.69-$353M-$3.90N/A
Olema PharmaceuticalsN/AN/A-$162.45M-$2.12N/A

In the previous week, Olema Pharmaceuticals had 6 more articles in the media than Arcus Biosciences. MarketBeat recorded 10 mentions for Olema Pharmaceuticals and 4 mentions for Arcus Biosciences. Olema Pharmaceuticals' average media sentiment score of 1.07 beat Arcus Biosciences' score of 1.05 indicating that Olema Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Arcus Biosciences
1 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Olema Pharmaceuticals
4 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Arcus Biosciences currently has a consensus target price of $38.30, suggesting a potential upside of 55.54%. Olema Pharmaceuticals has a consensus target price of $42.40, suggesting a potential upside of 314.87%. Given Olema Pharmaceuticals' stronger consensus rating and higher possible upside, analysts clearly believe Olema Pharmaceuticals is more favorable than Arcus Biosciences.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Arcus Biosciences
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.62
Olema Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.77

Arcus Biosciences has a beta of 0.81, indicating that its share price is 19% less volatile than the broader market. Comparatively, Olema Pharmaceuticals has a beta of 1.98, indicating that its share price is 98% more volatile than the broader market.

Summary

Olema Pharmaceuticals beats Arcus Biosciences on 13 of the 15 factors compared between the two stocks.

How does Olema Pharmaceuticals compare to Dyne Therapeutics?

Dyne Therapeutics (NASDAQ:DYN) and Olema Pharmaceuticals (NASDAQ:OLMA) are both healthcare companies, but which is the better stock? We will contrast the two companies based on the strength of their earnings, institutional ownership, valuation, risk, dividends, profitability, media sentiment and analyst recommendations.

Olema Pharmaceuticals' return on equity of -48.26% beat Dyne Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Dyne TherapeuticsN/A -64.30% -50.33%
Olema Pharmaceuticals N/A -48.26%-43.04%

Dyne Therapeutics presently has a consensus price target of $32.17, suggesting a potential upside of 76.64%. Olema Pharmaceuticals has a consensus price target of $42.40, suggesting a potential upside of 314.87%. Given Olema Pharmaceuticals' higher possible upside, analysts plainly believe Olema Pharmaceuticals is more favorable than Dyne Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Dyne Therapeutics
2 Sell rating(s)
1 Hold rating(s)
11 Buy rating(s)
2 Strong Buy rating(s)
2.81
Olema Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.77

In the previous week, Dyne Therapeutics had 25 more articles in the media than Olema Pharmaceuticals. MarketBeat recorded 35 mentions for Dyne Therapeutics and 10 mentions for Olema Pharmaceuticals. Olema Pharmaceuticals' average media sentiment score of 1.07 beat Dyne Therapeutics' score of 0.31 indicating that Olema Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Dyne Therapeutics
10 Very Positive mention(s)
2 Positive mention(s)
8 Neutral mention(s)
5 Negative mention(s)
1 Very Negative mention(s)
Neutral
Olema Pharmaceuticals
4 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Dyne Therapeutics is trading at a lower price-to-earnings ratio than Olema Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Dyne TherapeuticsN/AN/A-$446.21M-$3.33N/A
Olema PharmaceuticalsN/AN/A-$162.45M-$2.12N/A

Dyne Therapeutics has a beta of 1.08, indicating that its share price is 8% more volatile than the broader market. Comparatively, Olema Pharmaceuticals has a beta of 1.98, indicating that its share price is 98% more volatile than the broader market.

96.7% of Dyne Therapeutics shares are owned by institutional investors. Comparatively, 91.8% of Olema Pharmaceuticals shares are owned by institutional investors. 9.5% of Dyne Therapeutics shares are owned by company insiders. Comparatively, 12.6% of Olema Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Summary

Olema Pharmaceuticals beats Dyne Therapeutics on 9 of the 13 factors compared between the two stocks.

How does Olema Pharmaceuticals compare to GRAIL?

Olema Pharmaceuticals (NASDAQ:OLMA) and GRAIL (NASDAQ:GRAL) are both healthcare companies, but which is the better investment? We will compare the two companies based on the strength of their dividends, media sentiment, risk, institutional ownership, earnings, analyst recommendations, profitability and valuation.

Olema Pharmaceuticals has a beta of 1.98, indicating that its stock price is 98% more volatile than the broader market. Comparatively, GRAIL has a beta of 3.25, indicating that its stock price is 225% more volatile than the broader market.

In the previous week, Olema Pharmaceuticals had 1 more articles in the media than GRAIL. MarketBeat recorded 10 mentions for Olema Pharmaceuticals and 9 mentions for GRAIL. Olema Pharmaceuticals' average media sentiment score of 1.07 beat GRAIL's score of 0.96 indicating that Olema Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Olema Pharmaceuticals
4 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
GRAIL
3 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

91.8% of Olema Pharmaceuticals shares are owned by institutional investors. 12.6% of Olema Pharmaceuticals shares are owned by insiders. Comparatively, 1.8% of GRAIL shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

Olema Pharmaceuticals currently has a consensus price target of $42.40, indicating a potential upside of 314.87%. GRAIL has a consensus price target of $71.11, indicating a potential downside of 6.72%. Given Olema Pharmaceuticals' stronger consensus rating and higher possible upside, research analysts clearly believe Olema Pharmaceuticals is more favorable than GRAIL.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Olema Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.77
GRAIL
1 Sell rating(s)
5 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.45

Olema Pharmaceuticals has higher earnings, but lower revenue than GRAIL. GRAIL is trading at a lower price-to-earnings ratio than Olema Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Olema PharmaceuticalsN/AN/A-$162.45M-$2.12N/A
GRAIL$165.26M20.60-$408.35M-$9.75N/A

Olema Pharmaceuticals has a net margin of 0.00% compared to GRAIL's net margin of -236.95%. GRAIL's return on equity of -15.88% beat Olema Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Olema PharmaceuticalsN/A -48.26% -43.04%
GRAIL -236.95%-15.88%-14.02%

Summary

Olema Pharmaceuticals beats GRAIL on 11 of the 16 factors compared between the two stocks.

How does Olema Pharmaceuticals compare to Denali Therapeutics?

Denali Therapeutics (NASDAQ:DNLI) and Olema Pharmaceuticals (NASDAQ:OLMA) are both healthcare companies, but which is the superior business? We will contrast the two businesses based on the strength of their earnings, analyst recommendations, dividends, valuation, risk, profitability, institutional ownership and media sentiment.

Denali Therapeutics currently has a consensus target price of $35.85, indicating a potential upside of 69.97%. Olema Pharmaceuticals has a consensus target price of $42.40, indicating a potential upside of 314.87%. Given Olema Pharmaceuticals' stronger consensus rating and higher probable upside, analysts plainly believe Olema Pharmaceuticals is more favorable than Denali Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Denali Therapeutics
1 Sell rating(s)
2 Hold rating(s)
13 Buy rating(s)
0 Strong Buy rating(s)
2.75
Olema Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.77

92.9% of Denali Therapeutics shares are owned by institutional investors. Comparatively, 91.8% of Olema Pharmaceuticals shares are owned by institutional investors. 9.7% of Denali Therapeutics shares are owned by insiders. Comparatively, 12.6% of Olema Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

In the previous week, Olema Pharmaceuticals had 8 more articles in the media than Denali Therapeutics. MarketBeat recorded 10 mentions for Olema Pharmaceuticals and 2 mentions for Denali Therapeutics. Denali Therapeutics' average media sentiment score of 1.46 beat Olema Pharmaceuticals' score of 1.07 indicating that Denali Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Denali Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Olema Pharmaceuticals
4 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Olema Pharmaceuticals' return on equity of -48.26% beat Denali Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Denali TherapeuticsN/A -55.27% -44.24%
Olema Pharmaceuticals N/A -48.26%-43.04%

Olema Pharmaceuticals has lower revenue, but higher earnings than Denali Therapeutics. Denali Therapeutics is trading at a lower price-to-earnings ratio than Olema Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Denali Therapeutics$330.53M10.20-$512.54M-$2.84N/A
Olema PharmaceuticalsN/AN/A-$162.45M-$2.12N/A

Denali Therapeutics has a beta of 1.01, meaning that its stock price is 1% more volatile than the broader market. Comparatively, Olema Pharmaceuticals has a beta of 1.98, meaning that its stock price is 98% more volatile than the broader market.

Summary

Olema Pharmaceuticals beats Denali Therapeutics on 10 of the 14 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding OLMA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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OLMA vs. The Competition

MetricOlema PharmaceuticalsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$935.35M$3.85B$7.15B$12.72B
Dividend YieldN/A3.63%2.56%11.15%
P/E Ratio-4.8214.18274.1025.29
Price / SalesN/A1,477.55655.4598.96
Price / CashN/A106.6877.0451.44
Price / Book1.7415.1210.336.20
Net Income-$162.45M-$22.86M$3.50B$358.50M
7 Day Performance-4.93%-4.35%-3.33%-2.35%
1 Month Performance-2.11%-0.03%-0.41%-2.77%
1 Year Performance31.53%40.63%19.22%7.63%

Olema Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
OLMA
Olema Pharmaceuticals
2.6948 of 5 stars
$10.22
-4.4%
$42.40
+314.9%
+27.8%$935.35MN/AN/A70
AMLX
Amylyx Pharmaceuticals
3.9495 of 5 stars
$34.10
+0.0%
$36.50
+7.0%
+167.1%$3.80B$87.37MN/A200
RCUS
Arcus Biosciences
3.4239 of 5 stars
$29.39
-0.9%
$38.30
+30.3%
+114.0%$3.74B$247MN/A500
DYN
Dyne Therapeutics
3.1055 of 5 stars
$19.78
-18.5%
$34.42
+74.0%
+38.2%$3.69BN/AN/A100
GRAL
GRAIL
0.6883 of 5 stars
$80.34
0.0%
$67.78
-15.6%
+97.2%$3.59B$147.17MN/A1,360

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This page (NASDAQ:OLMA) was last updated on 9/12/2026 by MarketBeat.com Staff.
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