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WAVE Life Sciences (WVE) Competitors

WAVE Life Sciences logo
$5.29 +0.04 (+0.76%)
As of 08/21/2026 04:00 PM Eastern

WVE vs. DNLI, VKTX, LEGN, RCUS, and GMTX

Should you buy WAVE Life Sciences stock or one of its competitors? WAVE Life Sciences's main competitors and comparable companies include Denali Therapeutics (DNLI), Viking Therapeutics (VKTX), Legend Biotech (LEGN), Arcus Biosciences (RCUS), and Gemini Therapeutics (GMTX). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does WAVE Life Sciences compare to Denali Therapeutics?

WAVE Life Sciences (NASDAQ:WVE) and Denali Therapeutics (NASDAQ:DNLI) are both healthcare companies, but which is the better business? We will contrast the two companies based on the strength of their risk, analyst recommendations, earnings, institutional ownership, valuation, dividends, profitability and media sentiment.

WAVE Life Sciences has higher earnings, but lower revenue than Denali Therapeutics. Denali Therapeutics is trading at a lower price-to-earnings ratio than WAVE Life Sciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
WAVE Life Sciences$42.73M24.39-$204.38M-$1.09N/A
Denali Therapeutics$330.53M12.05-$512.54M-$2.84N/A

WAVE Life Sciences currently has a consensus target price of $22.53, suggesting a potential upside of 325.89%. Denali Therapeutics has a consensus target price of $35.92, suggesting a potential upside of 44.13%. Given WAVE Life Sciences' stronger consensus rating and higher probable upside, equities analysts plainly believe WAVE Life Sciences is more favorable than Denali Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
WAVE Life Sciences
1 Sell rating(s)
1 Hold rating(s)
14 Buy rating(s)
0 Strong Buy rating(s)
2.81
Denali Therapeutics
1 Sell rating(s)
2 Hold rating(s)
13 Buy rating(s)
0 Strong Buy rating(s)
2.75

Denali Therapeutics has a net margin of 0.00% compared to WAVE Life Sciences' net margin of -309.73%. WAVE Life Sciences' return on equity of -50.36% beat Denali Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
WAVE Life Sciences-309.73% -50.36% -40.06%
Denali Therapeutics N/A -55.27%-44.24%

WAVE Life Sciences has a beta of -1.26, meaning that its share price is 226% less volatile than the broader market. Comparatively, Denali Therapeutics has a beta of 1.01, meaning that its share price is 1% more volatile than the broader market.

89.7% of WAVE Life Sciences shares are held by institutional investors. Comparatively, 92.9% of Denali Therapeutics shares are held by institutional investors. 24.3% of WAVE Life Sciences shares are held by company insiders. Comparatively, 9.7% of Denali Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

In the previous week, Denali Therapeutics had 5 more articles in the media than WAVE Life Sciences. MarketBeat recorded 7 mentions for Denali Therapeutics and 2 mentions for WAVE Life Sciences. Denali Therapeutics' average media sentiment score of 1.32 beat WAVE Life Sciences' score of -0.97 indicating that Denali Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
WAVE Life Sciences
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Negative
Denali Therapeutics
5 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

WAVE Life Sciences beats Denali Therapeutics on 10 of the 16 factors compared between the two stocks.

How does WAVE Life Sciences compare to Viking Therapeutics?

Viking Therapeutics (NASDAQ:VKTX) and WAVE Life Sciences (NASDAQ:WVE) are both healthcare companies, but which is the better stock? We will compare the two companies based on the strength of their risk, media sentiment, dividends, institutional ownership, earnings, analyst recommendations, profitability and valuation.

76.0% of Viking Therapeutics shares are held by institutional investors. Comparatively, 89.7% of WAVE Life Sciences shares are held by institutional investors. 5.3% of Viking Therapeutics shares are held by company insiders. Comparatively, 24.3% of WAVE Life Sciences shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Viking Therapeutics currently has a consensus price target of $96.63, suggesting a potential upside of 185.11%. WAVE Life Sciences has a consensus price target of $22.53, suggesting a potential upside of 325.89%. Given WAVE Life Sciences' stronger consensus rating and higher probable upside, analysts clearly believe WAVE Life Sciences is more favorable than Viking Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Viking Therapeutics
1 Sell rating(s)
2 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.75
WAVE Life Sciences
1 Sell rating(s)
1 Hold rating(s)
14 Buy rating(s)
0 Strong Buy rating(s)
2.81

Viking Therapeutics has a beta of 0.69, meaning that its share price is 31% less volatile than the broader market. Comparatively, WAVE Life Sciences has a beta of -1.26, meaning that its share price is 226% less volatile than the broader market.

Viking Therapeutics has a net margin of 0.00% compared to WAVE Life Sciences' net margin of -309.73%. WAVE Life Sciences' return on equity of -50.36% beat Viking Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Viking TherapeuticsN/A -94.56% -82.75%
WAVE Life Sciences -309.73%-50.36%-40.06%

In the previous week, Viking Therapeutics had 5 more articles in the media than WAVE Life Sciences. MarketBeat recorded 7 mentions for Viking Therapeutics and 2 mentions for WAVE Life Sciences. Viking Therapeutics' average media sentiment score of 1.08 beat WAVE Life Sciences' score of -0.97 indicating that Viking Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Viking Therapeutics
3 Very Positive mention(s)
2 Positive mention(s)
0 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
WAVE Life Sciences
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Negative

WAVE Life Sciences has higher revenue and earnings than Viking Therapeutics. Viking Therapeutics is trading at a lower price-to-earnings ratio than WAVE Life Sciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Viking TherapeuticsN/AN/A-$359.64M-$4.66N/A
WAVE Life Sciences$42.73M24.39-$204.38M-$1.09N/A

Summary

WAVE Life Sciences beats Viking Therapeutics on 11 of the 16 factors compared between the two stocks.

How does WAVE Life Sciences compare to Legend Biotech?

Legend Biotech (NASDAQ:LEGN) and WAVE Life Sciences (NASDAQ:WVE) are both healthcare companies, but which is the better stock? We will contrast the two businesses based on the strength of their profitability, earnings, dividends, media sentiment, analyst recommendations, institutional ownership, risk and valuation.

Legend Biotech has a net margin of -7.21% compared to WAVE Life Sciences' net margin of -309.73%. Legend Biotech's return on equity of -8.71% beat WAVE Life Sciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Legend Biotech-7.21% -8.71% -5.40%
WAVE Life Sciences -309.73%-50.36%-40.06%

70.9% of Legend Biotech shares are held by institutional investors. Comparatively, 89.7% of WAVE Life Sciences shares are held by institutional investors. 0.0% of Legend Biotech shares are held by insiders. Comparatively, 24.3% of WAVE Life Sciences shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

WAVE Life Sciences has lower revenue, but higher earnings than Legend Biotech. Legend Biotech is trading at a lower price-to-earnings ratio than WAVE Life Sciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Legend Biotech$1.03B3.94-$296.80M-$0.25N/A
WAVE Life Sciences$42.73M24.39-$204.38M-$1.09N/A

In the previous week, Legend Biotech had 3 more articles in the media than WAVE Life Sciences. MarketBeat recorded 5 mentions for Legend Biotech and 2 mentions for WAVE Life Sciences. Legend Biotech's average media sentiment score of -0.14 beat WAVE Life Sciences' score of -0.97 indicating that Legend Biotech is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Legend Biotech
0 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
WAVE Life Sciences
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Negative

Legend Biotech currently has a consensus target price of $52.29, suggesting a potential upside of 139.62%. WAVE Life Sciences has a consensus target price of $22.53, suggesting a potential upside of 325.89%. Given WAVE Life Sciences' stronger consensus rating and higher possible upside, analysts clearly believe WAVE Life Sciences is more favorable than Legend Biotech.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Legend Biotech
1 Sell rating(s)
6 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.47
WAVE Life Sciences
1 Sell rating(s)
1 Hold rating(s)
14 Buy rating(s)
0 Strong Buy rating(s)
2.81

Legend Biotech has a beta of 0.37, indicating that its stock price is 63% less volatile than the broader market. Comparatively, WAVE Life Sciences has a beta of -1.26, indicating that its stock price is 226% less volatile than the broader market.

Summary

Legend Biotech and WAVE Life Sciences tied by winning 8 of the 16 factors compared between the two stocks.

How does WAVE Life Sciences compare to Arcus Biosciences?

WAVE Life Sciences (NASDAQ:WVE) and Arcus Biosciences (NYSE:RCUS) are both healthcare companies, but which is the superior business? We will contrast the two businesses based on the strength of their risk, earnings, analyst recommendations, media sentiment, valuation, profitability, dividends and institutional ownership.

WAVE Life Sciences has higher earnings, but lower revenue than Arcus Biosciences. Arcus Biosciences is trading at a lower price-to-earnings ratio than WAVE Life Sciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
WAVE Life Sciences$42.73M24.39-$204.38M-$1.09N/A
Arcus Biosciences$247M15.54-$353M-$3.90N/A

WAVE Life Sciences currently has a consensus target price of $22.53, indicating a potential upside of 325.89%. Arcus Biosciences has a consensus target price of $37.80, indicating a potential upside of 25.41%. Given WAVE Life Sciences' stronger consensus rating and higher possible upside, equities research analysts plainly believe WAVE Life Sciences is more favorable than Arcus Biosciences.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
WAVE Life Sciences
1 Sell rating(s)
1 Hold rating(s)
14 Buy rating(s)
0 Strong Buy rating(s)
2.81
Arcus Biosciences
1 Sell rating(s)
3 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.58

89.7% of WAVE Life Sciences shares are held by institutional investors. Comparatively, 92.9% of Arcus Biosciences shares are held by institutional investors. 24.3% of WAVE Life Sciences shares are held by insiders. Comparatively, 7.6% of Arcus Biosciences shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

WAVE Life Sciences has a net margin of -309.73% compared to Arcus Biosciences' net margin of -393.16%. WAVE Life Sciences' return on equity of -50.36% beat Arcus Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
WAVE Life Sciences-309.73% -50.36% -40.06%
Arcus Biosciences -393.16%-89.54%-45.61%

WAVE Life Sciences has a beta of -1.26, suggesting that its stock price is 226% less volatile than the broader market. Comparatively, Arcus Biosciences has a beta of 0.8, suggesting that its stock price is 20% less volatile than the broader market.

In the previous week, Arcus Biosciences had 4 more articles in the media than WAVE Life Sciences. MarketBeat recorded 6 mentions for Arcus Biosciences and 2 mentions for WAVE Life Sciences. Arcus Biosciences' average media sentiment score of 0.71 beat WAVE Life Sciences' score of -0.97 indicating that Arcus Biosciences is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
WAVE Life Sciences
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Negative
Arcus Biosciences
3 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

WAVE Life Sciences beats Arcus Biosciences on 11 of the 16 factors compared between the two stocks.

How does WAVE Life Sciences compare to Gemini Therapeutics?

Gemini Therapeutics (NASDAQ:GMTX) and WAVE Life Sciences (NASDAQ:WVE) are both healthcare companies, but which is the better investment? We will compare the two businesses based on the strength of their earnings, risk, media sentiment, analyst recommendations, institutional ownership, dividends, valuation and profitability.

Gemini Therapeutics has a net margin of 0.00% compared to WAVE Life Sciences' net margin of -309.73%. Gemini Therapeutics' return on equity of -38.78% beat WAVE Life Sciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Gemini TherapeuticsN/A -38.78% -35.88%
WAVE Life Sciences -309.73%-50.36%-40.06%

In the previous week, WAVE Life Sciences had 1 more articles in the media than Gemini Therapeutics. MarketBeat recorded 2 mentions for WAVE Life Sciences and 1 mentions for Gemini Therapeutics. Gemini Therapeutics' average media sentiment score of 0.75 beat WAVE Life Sciences' score of -0.97 indicating that Gemini Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Gemini Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
WAVE Life Sciences
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Negative

WAVE Life Sciences has a consensus price target of $22.53, suggesting a potential upside of 325.89%. Given WAVE Life Sciences' stronger consensus rating and higher possible upside, analysts plainly believe WAVE Life Sciences is more favorable than Gemini Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Gemini Therapeutics
0 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
0.00
WAVE Life Sciences
1 Sell rating(s)
1 Hold rating(s)
14 Buy rating(s)
0 Strong Buy rating(s)
2.81

75.4% of Gemini Therapeutics shares are held by institutional investors. Comparatively, 89.7% of WAVE Life Sciences shares are held by institutional investors. 12.9% of Gemini Therapeutics shares are held by company insiders. Comparatively, 24.3% of WAVE Life Sciences shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

Gemini Therapeutics has higher earnings, but lower revenue than WAVE Life Sciences. Gemini Therapeutics is trading at a lower price-to-earnings ratio than WAVE Life Sciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Gemini TherapeuticsN/AN/A-$71.87M-$1.00N/A
WAVE Life Sciences$42.73M24.39-$204.38M-$1.09N/A

Gemini Therapeutics has a beta of -0.12, indicating that its stock price is 112% less volatile than the broader market. Comparatively, WAVE Life Sciences has a beta of -1.26, indicating that its stock price is 226% less volatile than the broader market.

Summary

WAVE Life Sciences beats Gemini Therapeutics on 8 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding WVE and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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WVE vs. The Competition

MetricWAVE Life SciencesBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$1.04B$4.01B$7.37B$12.85B
Dividend YieldN/A3.64%2.53%11.08%
P/E Ratio-4.8511.62272.6024.24
Price / Sales24.391,338.17618.9699.78
Price / CashN/A105.1478.6253.99
Price / Book2.3016.8013.056.20
Net Income-$204.38M-$12.50M$3.47B$348.59M
7 Day Performance-2.22%3.29%2.09%0.08%
1 Month Performance-8.48%8.23%6.64%3.88%
1 Year Performance-47.88%55.05%25.02%16.98%

WAVE Life Sciences Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
WVE
WAVE Life Sciences
2.7798 of 5 stars
$5.29
+0.8%
$22.53
+325.9%
-47.9%$1.04B$42.73MN/A240
DNLI
Denali Therapeutics
3.3975 of 5 stars
$24.40
-1.7%
$35.92
+47.2%
+60.9%$3.97B$330.53MN/A430
VKTX
Viking Therapeutics
3.2335 of 5 stars
$33.19
+0.8%
$96.63
+191.1%
+30.3%$3.84BN/AN/A20
LEGN
Legend Biotech
2.834 of 5 stars
$20.37
+0.5%
$52.29
+156.7%
-38.6%$3.76B$1.03BN/A2,965
RCUS
Arcus Biosciences
2.9992 of 5 stars
$29.50
+2.2%
$37.80
+28.2%
+186.8%$3.67B$247MN/A500

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This page (NASDAQ:WVE) was last updated on 8/23/2026 by MarketBeat.com Staff.
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