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WAVE Life Sciences (WVE) Competitors

WAVE Life Sciences logo
$5.51 0.00 (0.00%)
Closing price 07/31/2026 04:00 PM Eastern
Extended Trading
$5.56 +0.06 (+1.00%)
As of 07/31/2026 07:34 PM Eastern
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WVE vs. LEGN, ACAD, EWTX, VKTX, and TNGX

Should you buy WAVE Life Sciences stock or one of its competitors? MarketBeat compares WAVE Life Sciences with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with WAVE Life Sciences include Legend Biotech (LEGN), ACADIA Pharmaceuticals (ACAD), Edgewise Therapeutics (EWTX), Viking Therapeutics (VKTX), and Tango Therapeutics (TNGX).

How does WAVE Life Sciences compare to Legend Biotech?

Legend Biotech (NASDAQ:LEGN) and WAVE Life Sciences (NASDAQ:WVE) are both healthcare companies, but which is the better investment? We will compare the two companies based on the strength of their media sentiment, analyst recommendations, valuation, dividends, profitability, earnings, institutional ownership and risk.

In the previous week, WAVE Life Sciences had 2 more articles in the media than Legend Biotech. MarketBeat recorded 17 mentions for WAVE Life Sciences and 15 mentions for Legend Biotech. Legend Biotech's average media sentiment score of 0.34 beat WAVE Life Sciences' score of -0.19 indicating that Legend Biotech is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Legend Biotech
5 Very Positive mention(s)
3 Positive mention(s)
4 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
WAVE Life Sciences
3 Very Positive mention(s)
0 Positive mention(s)
7 Neutral mention(s)
3 Negative mention(s)
1 Very Negative mention(s)
Neutral

Legend Biotech has a beta of 0.34, meaning that its stock price is 66% less volatile than the broader market. Comparatively, WAVE Life Sciences has a beta of -1.26, meaning that its stock price is 226% less volatile than the broader market.

Legend Biotech has a net margin of -21.98% compared to WAVE Life Sciences' net margin of -309.73%. Legend Biotech's return on equity of -24.92% beat WAVE Life Sciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Legend Biotech-21.98% -24.92% -14.87%
WAVE Life Sciences -309.73%-50.36%-40.06%

Legend Biotech currently has a consensus price target of $55.29, suggesting a potential upside of 198.04%. WAVE Life Sciences has a consensus price target of $23.88, suggesting a potential upside of 333.44%. Given WAVE Life Sciences' stronger consensus rating and higher possible upside, analysts plainly believe WAVE Life Sciences is more favorable than Legend Biotech.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Legend Biotech
1 Sell rating(s)
5 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.53
WAVE Life Sciences
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.94

WAVE Life Sciences has lower revenue, but higher earnings than Legend Biotech. Legend Biotech is trading at a lower price-to-earnings ratio than WAVE Life Sciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Legend Biotech$1.14B3.03-$296.80M-$0.68N/A
WAVE Life Sciences$42.73M25.41-$204.38M-$1.09N/A

70.9% of Legend Biotech shares are held by institutional investors. Comparatively, 89.7% of WAVE Life Sciences shares are held by institutional investors. 0.0% of Legend Biotech shares are held by company insiders. Comparatively, 24.3% of WAVE Life Sciences shares are held by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth.

Summary

WAVE Life Sciences beats Legend Biotech on 10 of the 17 factors compared between the two stocks.

How does WAVE Life Sciences compare to ACADIA Pharmaceuticals?

WAVE Life Sciences (NASDAQ:WVE) and ACADIA Pharmaceuticals (NASDAQ:ACAD) are both healthcare companies, but which is the superior business? We will compare the two businesses based on the strength of their profitability, institutional ownership, earnings, valuation, media sentiment, dividends, analyst recommendations and risk.

WAVE Life Sciences currently has a consensus target price of $23.88, indicating a potential upside of 333.44%. ACADIA Pharmaceuticals has a consensus target price of $32.31, indicating a potential upside of 24.88%. Given WAVE Life Sciences' stronger consensus rating and higher probable upside, equities research analysts clearly believe WAVE Life Sciences is more favorable than ACADIA Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
WAVE Life Sciences
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.94
ACADIA Pharmaceuticals
1 Sell rating(s)
4 Hold rating(s)
13 Buy rating(s)
0 Strong Buy rating(s)
2.67

In the previous week, WAVE Life Sciences had 3 more articles in the media than ACADIA Pharmaceuticals. MarketBeat recorded 17 mentions for WAVE Life Sciences and 14 mentions for ACADIA Pharmaceuticals. ACADIA Pharmaceuticals' average media sentiment score of 1.18 beat WAVE Life Sciences' score of -0.19 indicating that ACADIA Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
WAVE Life Sciences
3 Very Positive mention(s)
0 Positive mention(s)
7 Neutral mention(s)
3 Negative mention(s)
1 Very Negative mention(s)
Neutral
ACADIA Pharmaceuticals
11 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

ACADIA Pharmaceuticals has higher revenue and earnings than WAVE Life Sciences. WAVE Life Sciences is trading at a lower price-to-earnings ratio than ACADIA Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
WAVE Life Sciences$42.73M25.41-$204.38M-$1.09N/A
ACADIA Pharmaceuticals$1.07B4.13$391M$2.2011.76

WAVE Life Sciences has a beta of -1.26, suggesting that its share price is 226% less volatile than the broader market. Comparatively, ACADIA Pharmaceuticals has a beta of 0.81, suggesting that its share price is 19% less volatile than the broader market.

ACADIA Pharmaceuticals has a net margin of 34.30% compared to WAVE Life Sciences' net margin of -309.73%. ACADIA Pharmaceuticals' return on equity of 9.61% beat WAVE Life Sciences' return on equity.

Company Net Margins Return on Equity Return on Assets
WAVE Life Sciences-309.73% -50.36% -40.06%
ACADIA Pharmaceuticals 34.30%9.61%7.07%

89.7% of WAVE Life Sciences shares are held by institutional investors. Comparatively, 96.7% of ACADIA Pharmaceuticals shares are held by institutional investors. 24.3% of WAVE Life Sciences shares are held by company insiders. Comparatively, 26.2% of ACADIA Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

Summary

ACADIA Pharmaceuticals beats WAVE Life Sciences on 11 of the 17 factors compared between the two stocks.

How does WAVE Life Sciences compare to Edgewise Therapeutics?

WAVE Life Sciences (NASDAQ:WVE) and Edgewise Therapeutics (NASDAQ:EWTX) are both healthcare companies, but which is the superior stock? We will contrast the two companies based on the strength of their dividends, risk, earnings, profitability, valuation, analyst recommendations, institutional ownership and media sentiment.

Edgewise Therapeutics has a net margin of 0.00% compared to WAVE Life Sciences' net margin of -309.73%. Edgewise Therapeutics' return on equity of -32.55% beat WAVE Life Sciences' return on equity.

Company Net Margins Return on Equity Return on Assets
WAVE Life Sciences-309.73% -50.36% -40.06%
Edgewise Therapeutics N/A -32.55%-31.04%

WAVE Life Sciences presently has a consensus target price of $23.88, indicating a potential upside of 333.44%. Edgewise Therapeutics has a consensus target price of $48.75, indicating a potential upside of 26.85%. Given WAVE Life Sciences' stronger consensus rating and higher possible upside, equities analysts plainly believe WAVE Life Sciences is more favorable than Edgewise Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
WAVE Life Sciences
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.94
Edgewise Therapeutics
1 Sell rating(s)
1 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.82

WAVE Life Sciences has a beta of -1.26, indicating that its share price is 226% less volatile than the broader market. Comparatively, Edgewise Therapeutics has a beta of 0.3, indicating that its share price is 70% less volatile than the broader market.

In the previous week, WAVE Life Sciences had 11 more articles in the media than Edgewise Therapeutics. MarketBeat recorded 17 mentions for WAVE Life Sciences and 6 mentions for Edgewise Therapeutics. Edgewise Therapeutics' average media sentiment score of 1.24 beat WAVE Life Sciences' score of -0.19 indicating that Edgewise Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
WAVE Life Sciences
3 Very Positive mention(s)
0 Positive mention(s)
7 Neutral mention(s)
3 Negative mention(s)
1 Very Negative mention(s)
Neutral
Edgewise Therapeutics
4 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

89.7% of WAVE Life Sciences shares are owned by institutional investors. 24.3% of WAVE Life Sciences shares are owned by insiders. Comparatively, 21.3% of Edgewise Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

Edgewise Therapeutics has lower revenue, but higher earnings than WAVE Life Sciences. Edgewise Therapeutics is trading at a lower price-to-earnings ratio than WAVE Life Sciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
WAVE Life Sciences$42.73M25.41-$204.38M-$1.09N/A
Edgewise TherapeuticsN/AN/A-$167.79M-$1.66N/A

Summary

WAVE Life Sciences beats Edgewise Therapeutics on 9 of the 15 factors compared between the two stocks.

How does WAVE Life Sciences compare to Viking Therapeutics?

Viking Therapeutics (NASDAQ:VKTX) and WAVE Life Sciences (NASDAQ:WVE) are both healthcare companies, but which is the better business? We will compare the two companies based on the strength of their valuation, earnings, institutional ownership, profitability, dividends, risk, analyst recommendations and media sentiment.

Viking Therapeutics currently has a consensus price target of $97.88, suggesting a potential upside of 208.36%. WAVE Life Sciences has a consensus price target of $23.88, suggesting a potential upside of 333.44%. Given WAVE Life Sciences' stronger consensus rating and higher possible upside, analysts clearly believe WAVE Life Sciences is more favorable than Viking Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Viking Therapeutics
2 Sell rating(s)
1 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.67
WAVE Life Sciences
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.94

76.0% of Viking Therapeutics shares are held by institutional investors. Comparatively, 89.7% of WAVE Life Sciences shares are held by institutional investors. 5.3% of Viking Therapeutics shares are held by insiders. Comparatively, 24.3% of WAVE Life Sciences shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Viking Therapeutics has a net margin of 0.00% compared to WAVE Life Sciences' net margin of -309.73%. WAVE Life Sciences' return on equity of -50.36% beat Viking Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Viking TherapeuticsN/A -94.56% -82.75%
WAVE Life Sciences -309.73%-50.36%-40.06%

In the previous week, Viking Therapeutics had 20 more articles in the media than WAVE Life Sciences. MarketBeat recorded 37 mentions for Viking Therapeutics and 17 mentions for WAVE Life Sciences. Viking Therapeutics' average media sentiment score of 0.63 beat WAVE Life Sciences' score of -0.19 indicating that Viking Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Viking Therapeutics
14 Very Positive mention(s)
2 Positive mention(s)
6 Neutral mention(s)
6 Negative mention(s)
0 Very Negative mention(s)
Positive
WAVE Life Sciences
3 Very Positive mention(s)
0 Positive mention(s)
7 Neutral mention(s)
3 Negative mention(s)
1 Very Negative mention(s)
Neutral

WAVE Life Sciences has higher revenue and earnings than Viking Therapeutics. Viking Therapeutics is trading at a lower price-to-earnings ratio than WAVE Life Sciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Viking TherapeuticsN/AN/A-$359.64M-$4.66N/A
WAVE Life Sciences$42.73M25.41-$204.38M-$1.09N/A

Viking Therapeutics has a beta of 0.69, meaning that its stock price is 31% less volatile than the broader market. Comparatively, WAVE Life Sciences has a beta of -1.26, meaning that its stock price is 226% less volatile than the broader market.

Summary

WAVE Life Sciences beats Viking Therapeutics on 11 of the 15 factors compared between the two stocks.

How does WAVE Life Sciences compare to Tango Therapeutics?

Tango Therapeutics (NASDAQ:TNGX) and WAVE Life Sciences (NASDAQ:WVE) are both healthcare companies, but which is the better investment? We will contrast the two businesses based on the strength of their valuation, dividends, earnings, media sentiment, risk, institutional ownership, profitability and analyst recommendations.

Tango Therapeutics has higher revenue and earnings than WAVE Life Sciences. Tango Therapeutics is trading at a lower price-to-earnings ratio than WAVE Life Sciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Tango Therapeutics$62.38M63.03-$101.59M-$0.83N/A
WAVE Life Sciences$42.73M25.41-$204.38M-$1.09N/A

79.0% of Tango Therapeutics shares are owned by institutional investors. Comparatively, 89.7% of WAVE Life Sciences shares are owned by institutional investors. 6.5% of Tango Therapeutics shares are owned by insiders. Comparatively, 24.3% of WAVE Life Sciences shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Tango Therapeutics has a net margin of 0.00% compared to WAVE Life Sciences' net margin of -309.73%. Tango Therapeutics' return on equity of -41.54% beat WAVE Life Sciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Tango TherapeuticsN/A -41.54% -33.44%
WAVE Life Sciences -309.73%-50.36%-40.06%

In the previous week, WAVE Life Sciences had 9 more articles in the media than Tango Therapeutics. MarketBeat recorded 17 mentions for WAVE Life Sciences and 8 mentions for Tango Therapeutics. Tango Therapeutics' average media sentiment score of 1.41 beat WAVE Life Sciences' score of -0.19 indicating that Tango Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Tango Therapeutics
6 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
WAVE Life Sciences
3 Very Positive mention(s)
0 Positive mention(s)
7 Neutral mention(s)
3 Negative mention(s)
1 Very Negative mention(s)
Neutral

Tango Therapeutics currently has a consensus price target of $42.15, indicating a potential upside of 55.09%. WAVE Life Sciences has a consensus price target of $23.88, indicating a potential upside of 333.44%. Given WAVE Life Sciences' stronger consensus rating and higher possible upside, analysts clearly believe WAVE Life Sciences is more favorable than Tango Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Tango Therapeutics
1 Sell rating(s)
2 Hold rating(s)
13 Buy rating(s)
0 Strong Buy rating(s)
2.75
WAVE Life Sciences
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.94

Tango Therapeutics has a beta of 1.16, suggesting that its stock price is 16% more volatile than the broader market. Comparatively, WAVE Life Sciences has a beta of -1.26, suggesting that its stock price is 226% less volatile than the broader market.

Summary

Tango Therapeutics beats WAVE Life Sciences on 9 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding WVE and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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WVE vs. The Competition

MetricWAVE Life SciencesBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$1.09B$3.54B$6.85B$12.42B
Dividend YieldN/A3.78%2.59%10.03%
P/E Ratio-5.067.38282.3024.66
Price / Sales25.411,200.34563.1275.93
Price / CashN/A44.8028.6046.71
Price / Book1.7816.9610.966.07
Net Income-$204.38M-$12.56M$3.49B$347.99M
7 Day Performance-6.93%-1.77%-0.64%-0.44%
1 Month Performance-11.98%-8.39%-5.23%-4.81%
1 Year Performance-36.15%48.40%61.97%18.61%

WAVE Life Sciences Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
WVE
WAVE Life Sciences
3.0384 of 5 stars
$5.51
flat
$23.88
+333.4%
-36.2%$1.09B$42.73MN/A240
LEGN
Legend Biotech
3.0922 of 5 stars
$22.22
-5.6%
$55.38
+149.3%
-52.2%$4.37B$1.03BN/A2,965
ACAD
ACADIA Pharmaceuticals
4.5185 of 5 stars
$24.84
+0.0%
$33.17
+33.5%
+9.9%$4.25B$1.07B11.29510
EWTX
Edgewise Therapeutics
3.5016 of 5 stars
$40.84
+3.9%
$48.75
+19.4%
+168.6%$4.23BN/AN/A60
VKTX
Viking Therapeutics
3.3756 of 5 stars
$34.79
-1.7%
$97.00
+178.8%
-2.9%$4.11BN/AN/A20

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This page (NASDAQ:WVE) was last updated on 8/3/2026 by MarketBeat.com Staff.
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