| 5/18/2020 | Redmile Group LLC | 2,927,352 | $27.43M | 0.8% | -12.0% | 8.390% | |
| 5/18/2020 | Voloridge Investment Management LLC | 48,010 | $0.45M | 0.0% | N/A | 0.138% | |
| 5/15/2020 | Morgan Stanley | 685,635 | $6.42M | 0.0% | +857.5% | 1.965% | |
| 5/14/2020 | Virtus ETF Advisers LLC | 9,558 | $90K | 0.0% | -12.7% | 0.027% | |
| 5/14/2020 | Wells Fargo & Company MN | 15,120 | $0.14M | 0.0% | +18.9% | 0.043% | |
| 5/14/2020 | Geode Capital Management LLC | 294,033 | $2.76M | 0.0% | +5.0% | 0.848% | |
| 5/14/2020 | Tekla Capital Management LLC | 128,146 | $1.20M | 0.1% | +28.1% | 0.369% | |
| 5/14/2020 | Wellington Management Group LLP | 3,031,294 | $28.40M | 0.0% | -5.4% | 8.738% | |
| 5/14/2020 | Legal & General Group Plc | 5,874 | $55K | 0.0% | -15.6% | 0.017% | |
| 5/14/2020 | Burrage Capital Management LLC | 56,699 | $0.56M | 0.5% | -46.5% | 0.163% | |
|
| 5/14/2020 | Alliancebernstein L.P. | 37,900 | $0.36M | 0.0% | +56.6% | 0.109% | |
| 5/14/2020 | Nuveen Asset Management LLC | 110,077 | $1.03M | 0.0% | +41.4% | 0.317% | |
| 5/14/2020 | Primecap Management Co. CA | 1,235,588 | $11.58M | 0.0% | -4.5% | 3.562% | |
| 5/13/2020 | Parametric Portfolio Associates LLC | 10,830 | $0.10M | 0.0% | -73.5% | 0.031% | |
| 5/13/2020 | WS Management Lllp | 52,682 | $0.49M | 0.1% | -4.9% | 0.152% | |
| 5/13/2020 | BNP Paribas Arbitrage SA | 6,989 | $65K | 0.0% | +163.4% | 0.020% | |
| 5/13/2020 | Pictet Asset Management Ltd. | 194,634 | $1.82M | 0.0% | +238.4% | 0.561% | |
| 5/12/2020 | Spark Investment Management LLC | 80,519 | $0.75M | 0.4% | -37.6% | 0.232% | |
| 5/12/2020 | JPMorgan Chase & Co. | 781,110 | $7.32M | 0.0% | +179.6% | 2.252% | |
| 5/11/2020 | State Street Corp | 509,236 | $4.77M | 0.0% | +5.8% | 1.468% | |
| 5/7/2020 | Matisse Capital | 70,991 | $0.67M | 0.3% | +3.3% | 0.205% | |
| 5/6/2020 | Russell Investments Group Ltd. | 43,298 | $0.41M | 0.0% | N/A | 0.125% | |
| 5/6/2020 | Bank of New York Mellon Corp | 87,039 | $0.82M | 0.0% | -3.0% | 0.251% | |
| 5/1/2020 | BlackRock Inc. | 1,814,881 | $17.01M | 0.0% | -0.9% | 5.254% | |
| 3/5/2020 | Nuveen Asset Management LLC | 77,859 | $0.62M | 0.0% | -3.0% | 0.225% | |
| 2/18/2020 | Janus Henderson Group PLC | 802,742 | $6.43M | 0.0% | -80.3% | 2.341% | |
| 2/14/2020 | Point72 Asset Management L.P. | 158,400 | $1.27M | 0.0% | +252.0% | 0.462% | |
| 2/14/2020 | Cubist Systematic Strategies LLC | 7,422 | $59K | 0.0% | +209.3% | 0.022% | |
| 2/14/2020 | Bank of America Corp DE | 11,050 | $89K | 0.0% | -27.0% | 0.032% | |
| 2/14/2020 | Bank of New York Mellon Corp | 89,687 | $0.72M | 0.0% | +4.1% | 0.262% | |
| 2/14/2020 | ArrowMark Colorado Holdings LLC | 991,598 | $7.95M | 0.1% | +0.4% | 2.892% | |
| 2/13/2020 | Amia Capital LLP | 20,646 | $0.17M | 0.0% | N/A | 0.060% | |
| 2/13/2020 | Platinum Investment Management Ltd. | 68,957 | $0.55M | 0.0% | -2.8% | 0.201% | |
| 2/12/2020 | Matisse Capital | 68,711 | $0.55M | 0.4% | +3.3% | 0.200% | |
| 2/12/2020 | Credit Suisse AG | 12,870 | $0.10M | 0.0% | -9.1% | 0.038% | |
| 2/12/2020 | ProShare Advisors LLC | 10,468 | $84K | 0.0% | -11.6% | 0.031% | |
| 2/12/2020 | Citigroup Inc. | 46,234 | $0.37M | 0.0% | +1,711.0% | 0.135% | |
| 2/12/2020 | Pictet Asset Management Ltd. | 57,510 | $0.46M | 0.0% | N/A | 0.168% | |
| 2/11/2020 | Spark Investment Management LLC | 129,000 | $1.03M | 0.1% | -45.0% | 0.376% | |
| 2/7/2020 | FMR LLC | 207,812 | $1.67M | 0.0% | -35.9% | 0.606% | |
| 2/7/2020 | Charles Schwab Investment Management Inc. | 118,445 | $0.95M | 0.0% | +2.1% | 0.345% | |
| 2/6/2020 | State Street Corp | 481,256 | $3.86M | 0.0% | -2.4% | 1.403% | |
| 2/5/2020 | New York State Common Retirement Fund | 20,200 | $0.16M | 0.0% | -19.2% | 0.059% | |
| 1/31/2020 | NJ State Employees Deferred Compensation Plan | 11,700 | $94K | 0.0% | N/A | 0.034% | |
| 1/27/2020 | California Public Employees Retirement System | 38,600 | $0.31M | 0.0% | N/A | 0.113% | |
| 1/17/2020 | Assenagon Asset Management S.A. | 67,140 | $0.54M | 0.0% | N/A | 0.196% | |
| 11/27/2019 | Redmile Group LLC | 3,177,760 | $65.24M | 2.2% | +16.8% | 9.267% | |
| 11/27/2019 | Voloridge Investment Management LLC | 12,899 | $0.27M | 0.0% | -42.5% | 0.038% | |
| 11/27/2019 | Barclays PLC | 23,459 | $0.48M | 0.0% | +39.5% | 0.068% | |
| 11/27/2019 | Point72 Asset Management L.P. | 45,000 | $0.92M | 0.0% | +3.4% | 0.131% | |
| 11/27/2019 | California State Teachers Retirement System | 35,089 | $0.72M | 0.0% | +1.2% | 0.102% | |
| 11/27/2019 | State Street Corp | 493,127 | $10.12M | 0.0% | -2.0% | 1.438% | |
| 10/28/2019 | Matisse Capital | 66,486 | $1.37M | 1.7% | +9.3% | 0.194% | |
| 10/23/2019 | Rhumbline Advisers | 29,160 | $0.60M | 0.0% | +2.2% | 0.085% | |
| 10/18/2019 | Bailard Inc. | 85,000 | $1.75M | 0.1% | +2.4% | 0.248% | |
| 10/18/2019 | Clear Street Markets LLC | 15,477 | $0.32M | 0.0% | -29.8% | 0.045% | |
| 8/17/2019 | Platinum Investment Management Ltd. | 70,942 | $1.85M | 0.0% | +48.9% | 0.207% | |
| 8/16/2019 | United Services Automobile Association | 48,388 | $1.28M | 0.0% | N/A | 0.141% | |
| 8/15/2019 | Voloridge Investment Management LLC | 22,416 | $0.59M | 0.0% | N/A | 0.065% | |
| 8/15/2019 | Nuveen Asset Management LLC | 77,725 | $2.03M | 0.0% | N/A | 0.227% | |
| 8/15/2019 | Price T Rowe Associates Inc. MD | 1,094,013 | $28.54M | 0.0% | -27.7% | 3.191% | |
| 8/15/2019 | UBS Asset Management Americas Inc. | 8,507 | $0.22M | 0.0% | -94.0% | 0.025% | |
| 8/14/2019 | D. E. Shaw & Co. Inc. | 85,979 | $2.24M | 0.0% | -64.6% | 0.251% | |
| 8/14/2019 | Cubist Systematic Strategies LLC | 1,800 | $47K | 0.0% | -91.5% | 0.005% | |
| 8/14/2019 | Point72 Asset Management L.P. | 43,500 | $1.14M | 0.0% | -92.5% | 0.127% | |
| 8/14/2019 | Morgan Stanley | 18,692 | $0.49M | 0.0% | +140.6% | 0.055% | |
| 8/14/2019 | Bank of America Corp DE | 32,310 | $0.84M | 0.0% | +16.9% | 0.094% | |
| 8/14/2019 | Vanguard Group Inc. | 392,888 | $10.25M | 0.0% | -0.3% | 1.146% | |
| 8/13/2019 | BlackRock Inc. | 1,811,996 | $47.28M | 0.0% | +6.7% | 5.286% | |
| 8/13/2019 | Virtus ETF Advisers LLC | 10,387 | $0.27M | 0.1% | +93.3% | 0.030% | |
| 8/13/2019 | WS Management Lllp | 61,585 | $1.61M | 0.1% | -10.7% | 0.180% | |
| 8/13/2019 | Parametric Portfolio Associates LLC | 21,187 | $0.55M | 0.0% | -14.3% | 0.062% | |
| 8/13/2019 | Athanor Capital LP | 21,700 | $0.57M | 0.1% | N/A | 0.063% | |
| 8/13/2019 | Foresite Capital Management III LLC | 139,900 | $3.65M | 1.2% | -15.2% | 0.408% | |
| 8/13/2019 | Northern Trust Corp | 265,291 | $6.92M | 0.0% | +2.0% | 0.774% | |
| 8/13/2019 | Matisse Capital | 60,826 | $1.59M | 2.0% | +34.8% | 0.177% | |
| 8/12/2019 | Renaissance Technologies LLC | 19,100 | $0.50M | 0.0% | +131.6% | 0.056% | |
| 8/12/2019 | Bank of New York Mellon Corp | 90,485 | $2.36M | 0.0% | +9.4% | 0.264% | |
| 8/12/2019 | Quantamental Technologies LLC | 1,691 | $44K | 0.0% | N/A | 0.005% | |
| 8/12/2019 | Fosun International Ltd | 70,088 | $1.84M | 0.1% | +18.6% | 0.204% | |
| 8/10/2019 | Charles Schwab Investment Management Inc. | 115,769 | $3.02M | 0.0% | +8.7% | 0.338% | |
| 8/9/2019 | Bank of Montreal Can | 2,106 | $55K | 0.0% | +590.5% | 0.006% | |
| 8/8/2019 | Allianz Asset Management GmbH | 41,502 | $1.08M | 0.0% | -60.4% | 0.121% | |
| 8/8/2019 | Mitsubishi UFJ Kokusai Asset Management Co. Ltd. | 3,614 | $94K | 0.0% | +18.7% | 0.011% | |
| 8/7/2019 | Janus Henderson Group PLC | 3,392,298 | $88.51M | 0.0% | +16.1% | 9.900% | |
| 8/6/2019 | Wells Fargo & Company MN | 21,539 | $0.56M | 0.0% | -93.7% | 0.063% | |
| 8/5/2019 | State Board of Administration of Florida Retirement System | 11,656 | $0.30M | 0.0% | +31.6% | 0.034% | |
| 8/2/2019 | Swiss National Bank | 34,200 | $0.89M | 0.0% | +2.4% | 0.100% | |
| 8/1/2019 | DekaBank Deutsche Girozentrale | 23,000 | $0.60M | 0.0% | N/A | 0.067% | |
| 7/31/2019 | Janus Henderson Group PLC | 3,392,298 | $88.51M | 0.0% | +16.1% | 9.900% | |
| 7/30/2019 | Aperio Group LLC | 1,948 | $51K | 0.0% | N/A | 0.006% | |
| 7/30/2019 | BNP Paribas Arbitrage SA | 2,262 | $59K | 0.0% | -46.3% | 0.007% | |
| 7/30/2019 | Zurcher Kantonalbank Zurich Cantonalbank | 1,583 | $41K | 0.0% | -51.5% | 0.005% | |
| 6/30/2019 | Bailard Inc. | 83,000 | $2.17M | 0.1% | +97.6% | 0.242% | |
| 6/30/2019 | Clear Street Markets LLC | 22,058 | $0.58M | 0.1% | N/A | 0.064% | |
| 6/16/2019 | FMR LLC | 396,112 | $15.39M | 0.0% | -47.7% | 1.156% | |
| 6/16/2019 | Redmile Group LLC | 2,831,507 | $110M | 3.2% | +26.5% | 8.265% | |
| 6/16/2019 | Marshall Wace North America L.P. | 220,321 | $8.56M | 0.1% | N/A | 0.643% | |
| 6/16/2019 | Marshall Wace LLP | 59,629 | $2.32M | 0.0% | N/A | 0.174% | |
| 5/13/2019 | WS Management Lllp | 68,977 | $2.68M | 0.2% | -12.0% | 0.201% | |
