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Lyell Immunopharma (LYEL) Competitors

Lyell Immunopharma logo
$10.53 -0.62 (-5.56%)
Closing price 09/23/2026 04:00 PM Eastern
Extended Trading
$10.54 +0.01 (+0.09%)
As of 09/23/2026 04:10 PM Eastern
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LYEL vs. CRVS, SVRA, MLTX, JANX, and CVAC

Should you buy Lyell Immunopharma stock or one of its competitors? Lyell Immunopharma's main competitors and comparable companies include Corvus Pharmaceuticals (CRVS), Savara (SVRA), MoonLake Immunotherapeutics (MLTX), Janux Therapeutics (JANX), and CureVac (CVAC). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Lyell Immunopharma compare to Corvus Pharmaceuticals?

Lyell Immunopharma (NASDAQ:LYEL) and Corvus Pharmaceuticals (NASDAQ:CRVS) are both small-cap healthcare companies, but which is the superior investment? We will compare the two companies based on the strength of their analyst recommendations, dividends, valuation, earnings, profitability, risk, institutional ownership and media sentiment.

Corvus Pharmaceuticals has lower revenue, but higher earnings than Lyell Immunopharma. Corvus Pharmaceuticals is trading at a lower price-to-earnings ratio than Lyell Immunopharma, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Lyell Immunopharma$40K6,449.63-$274.45M-$12.83N/A
Corvus PharmaceuticalsN/AN/A-$15.28M-$0.61N/A

Corvus Pharmaceuticals has a net margin of 0.00% compared to Lyell Immunopharma's net margin of -920,285.25%. Corvus Pharmaceuticals' return on equity of -36.15% beat Lyell Immunopharma's return on equity.

Company Net Margins Return on Equity Return on Assets
Lyell Immunopharma-920,285.25% -91.62% -70.50%
Corvus Pharmaceuticals N/A -36.15%-33.62%

Lyell Immunopharma presently has a consensus target price of $40.86, suggesting a potential upside of 288.01%. Corvus Pharmaceuticals has a consensus target price of $33.33, suggesting a potential upside of 165.82%. Given Lyell Immunopharma's higher probable upside, analysts plainly believe Lyell Immunopharma is more favorable than Corvus Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Lyell Immunopharma
1 Sell rating(s)
1 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.78
Corvus Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.88

Lyell Immunopharma has a beta of -0.04, meaning that its stock price is 104% less volatile than the broader market. Comparatively, Corvus Pharmaceuticals has a beta of 0.87, meaning that its stock price is 13% less volatile than the broader market.

In the previous week, Corvus Pharmaceuticals had 2 more articles in the media than Lyell Immunopharma. MarketBeat recorded 3 mentions for Corvus Pharmaceuticals and 1 mentions for Lyell Immunopharma. Corvus Pharmaceuticals' average media sentiment score of 0.36 beat Lyell Immunopharma's score of 0.00 indicating that Corvus Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Lyell Immunopharma
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Corvus Pharmaceuticals
1 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

66.1% of Lyell Immunopharma shares are owned by institutional investors. Comparatively, 46.6% of Corvus Pharmaceuticals shares are owned by institutional investors. 6.2% of Lyell Immunopharma shares are owned by insiders. Comparatively, 19.7% of Corvus Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Summary

Corvus Pharmaceuticals beats Lyell Immunopharma on 10 of the 14 factors compared between the two stocks.

How does Lyell Immunopharma compare to Savara?

Savara (NASDAQ:SVRA) and Lyell Immunopharma (NASDAQ:LYEL) are both small-cap healthcare companies, but which is the better stock? We will contrast the two businesses based on the strength of their analyst recommendations, valuation, dividends, media sentiment, risk, profitability, earnings and institutional ownership.

Savara has higher earnings, but lower revenue than Lyell Immunopharma. Savara is trading at a lower price-to-earnings ratio than Lyell Immunopharma, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
SavaraN/AN/A-$118.84M-$0.58N/A
Lyell Immunopharma$40K6,449.63-$274.45M-$12.83N/A

In the previous week, Savara and Savara both had 1 articles in the media. Savara's average media sentiment score of 1.02 beat Lyell Immunopharma's score of 0.00 indicating that Savara is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Savara
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Lyell Immunopharma
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Savara has a beta of 0.25, meaning that its stock price is 75% less volatile than the broader market. Comparatively, Lyell Immunopharma has a beta of -0.04, meaning that its stock price is 104% less volatile than the broader market.

Savara currently has a consensus price target of $10.00, suggesting a potential upside of 100.00%. Lyell Immunopharma has a consensus price target of $40.86, suggesting a potential upside of 288.01%. Given Lyell Immunopharma's higher probable upside, analysts clearly believe Lyell Immunopharma is more favorable than Savara.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Savara
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.88
Lyell Immunopharma
1 Sell rating(s)
1 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.78

Savara has a net margin of 0.00% compared to Lyell Immunopharma's net margin of -920,285.25%. Savara's return on equity of -90.28% beat Lyell Immunopharma's return on equity.

Company Net Margins Return on Equity Return on Assets
SavaraN/A -90.28% -68.95%
Lyell Immunopharma -920,285.25%-91.62%-70.50%

87.9% of Savara shares are owned by institutional investors. Comparatively, 66.1% of Lyell Immunopharma shares are owned by institutional investors. 5.3% of Savara shares are owned by insiders. Comparatively, 6.2% of Lyell Immunopharma shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Summary

Savara beats Lyell Immunopharma on 9 of the 13 factors compared between the two stocks.

How does Lyell Immunopharma compare to MoonLake Immunotherapeutics?

MoonLake Immunotherapeutics (NASDAQ:MLTX) and Lyell Immunopharma (NASDAQ:LYEL) are both small-cap healthcare companies, but which is the better business? We will contrast the two businesses based on the strength of their analyst recommendations, risk, valuation, profitability, earnings, institutional ownership, dividends and media sentiment.

MoonLake Immunotherapeutics has a beta of 1.04, meaning that its stock price is 4% more volatile than the broader market. Comparatively, Lyell Immunopharma has a beta of -0.04, meaning that its stock price is 104% less volatile than the broader market.

MoonLake Immunotherapeutics has a net margin of 0.00% compared to Lyell Immunopharma's net margin of -920,285.25%. MoonLake Immunotherapeutics' return on equity of -82.53% beat Lyell Immunopharma's return on equity.

Company Net Margins Return on Equity Return on Assets
MoonLake ImmunotherapeuticsN/A -82.53% -58.17%
Lyell Immunopharma -920,285.25%-91.62%-70.50%

MoonLake Immunotherapeutics has higher earnings, but lower revenue than Lyell Immunopharma. MoonLake Immunotherapeutics is trading at a lower price-to-earnings ratio than Lyell Immunopharma, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
MoonLake ImmunotherapeuticsN/AN/A-$227.32M-$3.84N/A
Lyell Immunopharma$40K6,449.63-$274.45M-$12.83N/A

93.9% of MoonLake Immunotherapeutics shares are owned by institutional investors. Comparatively, 66.1% of Lyell Immunopharma shares are owned by institutional investors. 10.4% of MoonLake Immunotherapeutics shares are owned by company insiders. Comparatively, 6.2% of Lyell Immunopharma shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

In the previous week, MoonLake Immunotherapeutics had 1 more articles in the media than Lyell Immunopharma. MarketBeat recorded 2 mentions for MoonLake Immunotherapeutics and 1 mentions for Lyell Immunopharma. MoonLake Immunotherapeutics' average media sentiment score of 0.67 beat Lyell Immunopharma's score of 0.00 indicating that MoonLake Immunotherapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
MoonLake Immunotherapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Lyell Immunopharma
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

MoonLake Immunotherapeutics currently has a consensus target price of $24.57, suggesting a potential upside of 90.48%. Lyell Immunopharma has a consensus target price of $40.86, suggesting a potential upside of 288.01%. Given Lyell Immunopharma's stronger consensus rating and higher probable upside, analysts plainly believe Lyell Immunopharma is more favorable than MoonLake Immunotherapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
MoonLake Immunotherapeutics
3 Sell rating(s)
4 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.44
Lyell Immunopharma
1 Sell rating(s)
1 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.78

Summary

MoonLake Immunotherapeutics beats Lyell Immunopharma on 11 of the 16 factors compared between the two stocks.

How does Lyell Immunopharma compare to Janux Therapeutics?

Janux Therapeutics (NASDAQ:JANX) and Lyell Immunopharma (NASDAQ:LYEL) are both small-cap healthcare companies, but which is the better stock? We will contrast the two companies based on the strength of their earnings, profitability, institutional ownership, analyst recommendations, valuation, dividends, media sentiment and risk.

Janux Therapeutics currently has a consensus target price of $36.46, indicating a potential upside of 120.71%. Lyell Immunopharma has a consensus target price of $40.86, indicating a potential upside of 288.01%. Given Lyell Immunopharma's stronger consensus rating and higher probable upside, analysts clearly believe Lyell Immunopharma is more favorable than Janux Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Janux Therapeutics
2 Sell rating(s)
2 Hold rating(s)
10 Buy rating(s)
1 Strong Buy rating(s)
2.67
Lyell Immunopharma
1 Sell rating(s)
1 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.78

75.4% of Janux Therapeutics shares are owned by institutional investors. Comparatively, 66.1% of Lyell Immunopharma shares are owned by institutional investors. 7.9% of Janux Therapeutics shares are owned by insiders. Comparatively, 6.2% of Lyell Immunopharma shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

In the previous week, Janux Therapeutics had 2 more articles in the media than Lyell Immunopharma. MarketBeat recorded 3 mentions for Janux Therapeutics and 1 mentions for Lyell Immunopharma. Lyell Immunopharma's average media sentiment score of 0.00 beat Janux Therapeutics' score of -0.44 indicating that Lyell Immunopharma is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Janux Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral
Lyell Immunopharma
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Janux Therapeutics has a net margin of 0.00% compared to Lyell Immunopharma's net margin of -920,285.25%. Janux Therapeutics' return on equity of -11.89% beat Lyell Immunopharma's return on equity.

Company Net Margins Return on Equity Return on Assets
Janux TherapeuticsN/A -11.89% -11.13%
Lyell Immunopharma -920,285.25%-91.62%-70.50%

Janux Therapeutics has a beta of 2.53, indicating that its stock price is 153% more volatile than the broader market. Comparatively, Lyell Immunopharma has a beta of -0.04, indicating that its stock price is 104% less volatile than the broader market.

Janux Therapeutics has higher revenue and earnings than Lyell Immunopharma. Janux Therapeutics is trading at a lower price-to-earnings ratio than Lyell Immunopharma, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Janux Therapeutics$10M101.00-$113.62M-$1.64N/A
Lyell Immunopharma$40K6,449.63-$274.45M-$12.83N/A

Summary

Janux Therapeutics beats Lyell Immunopharma on 11 of the 16 factors compared between the two stocks.

How does Lyell Immunopharma compare to CureVac?

CureVac (NASDAQ:CVAC) and Lyell Immunopharma (NASDAQ:LYEL) are both small-cap healthcare companies, but which is the superior business? We will contrast the two businesses based on the strength of their dividends, earnings, profitability, institutional ownership, media sentiment, analyst recommendations, valuation and risk.

Lyell Immunopharma has a consensus price target of $40.86, indicating a potential upside of 288.01%. Given Lyell Immunopharma's stronger consensus rating and higher possible upside, analysts plainly believe Lyell Immunopharma is more favorable than CureVac.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
CureVac
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
Lyell Immunopharma
1 Sell rating(s)
1 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.78

CureVac has a net margin of 199.92% compared to Lyell Immunopharma's net margin of -920,285.25%. CureVac's return on equity of -23.03% beat Lyell Immunopharma's return on equity.

Company Net Margins Return on Equity Return on Assets
CureVac199.92% -23.03% -19.09%
Lyell Immunopharma -920,285.25%-91.62%-70.50%

CureVac has higher revenue and earnings than Lyell Immunopharma. Lyell Immunopharma is trading at a lower price-to-earnings ratio than CureVac, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
CureVac$70.74M14.78$175.50M$0.726.47
Lyell Immunopharma$40K6,449.63-$274.45M-$12.83N/A

In the previous week, Lyell Immunopharma had 1 more articles in the media than CureVac. MarketBeat recorded 1 mentions for Lyell Immunopharma and 0 mentions for CureVac. CureVac's average media sentiment score of 0.00 equaled Lyell Immunopharma'saverage media sentiment score.

Company Overall Sentiment
CureVac Neutral
Lyell Immunopharma Neutral

CureVac has a beta of 1.77, indicating that its stock price is 77% more volatile than the broader market. Comparatively, Lyell Immunopharma has a beta of -0.04, indicating that its stock price is 104% less volatile than the broader market.

17.3% of CureVac shares are held by institutional investors. Comparatively, 66.1% of Lyell Immunopharma shares are held by institutional investors. 2.2% of CureVac shares are held by company insiders. Comparatively, 6.2% of Lyell Immunopharma shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.

Summary

CureVac and Lyell Immunopharma tied by winning 8 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding LYEL and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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LYEL vs. The Competition

MetricLyell ImmunopharmaBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$273.22M$3.98B$7.31B$13.29B
Dividend YieldN/A3.63%2.52%12.57%
P/E Ratio-0.8213.88274.0225.69
Price / Sales6,449.631,311.42632.7676.07
Price / CashN/A113.2977.8052.76
Price / Book0.9015.3010.446.32
Net Income-$274.45M-$22.82M$3.49B$359.73M
7 Day Performance-2.50%-1.71%-0.66%0.17%
1 Month Performance-28.56%-6.17%-3.16%-3.27%
1 Year Performance-21.71%30.64%15.15%5.58%

Lyell Immunopharma Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
LYEL
Lyell Immunopharma
2.8986 of 5 stars
$10.53
-5.6%
$40.86
+288.0%
-20.1%$273.22M$40KN/A161
CRVS
Corvus Pharmaceuticals
2.1621 of 5 stars
$12.95
-1.2%
$33.33
+157.4%
+104.9%$1.10BN/AN/A37
SVRA
Savara
2.0724 of 5 stars
$5.26
-1.5%
$10.00
+90.1%
+43.7%$1.10BN/AN/A70
MLTX
MoonLake Immunotherapeutics
2.3441 of 5 stars
$12.20
-3.8%
$24.57
+101.4%
-75.4%$1.08BN/AN/A130
JANX
Janux Therapeutics
2.605 of 5 stars
$16.44
-5.0%
$36.46
+121.8%
-28.1%$1.06B$10MN/A113

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This page (NASDAQ:LYEL) was last updated on 9/24/2026 by MarketBeat.com Staff.
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