Free Trial

Lyell Immunopharma (LYEL) Competitors

Lyell Immunopharma logo
$12.31 +0.34 (+2.84%)
Closing price 06/8/2026 04:00 PM Eastern
Extended Trading
$12.30 -0.01 (-0.04%)
As of 06/8/2026 07:39 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

LYEL vs. PURR, AMLX, ANAB, DMRA, and VIR

Should you buy Lyell Immunopharma stock or one of its competitors? MarketBeat compares Lyell Immunopharma with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Lyell Immunopharma include Hyperliquid Strategies (PURR), Amylyx Pharmaceuticals (AMLX), AnaptysBio (ANAB), Damora Therapeutics, Inc. Common Stock (DMRA), and Vir Biotechnology (VIR). These companies are all part of the "pharmaceutical products" industry.

How does Lyell Immunopharma compare to Hyperliquid Strategies?

Hyperliquid Strategies (NASDAQ:PURR) and Lyell Immunopharma (NASDAQ:LYEL) are both small-cap pharmaceutical products companies, but which is the superior investment? We will contrast the two companies based on the strength of their media sentiment, risk, analyst recommendations, profitability, valuation, dividends, institutional ownership and earnings.

Hyperliquid Strategies has a beta of 1.64, meaning that its stock price is 64% more volatile than the broader market. Comparatively, Lyell Immunopharma has a beta of -0.09, meaning that its stock price is 109% less volatile than the broader market.

Hyperliquid Strategies has higher revenue and earnings than Lyell Immunopharma. Hyperliquid Strategies is trading at a lower price-to-earnings ratio than Lyell Immunopharma, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Hyperliquid Strategies$1M1,288.49-$16.01M-$7.37N/A
Lyell Immunopharma$31K9,265.86-$274.45M-$13.80N/A

9.5% of Hyperliquid Strategies shares are owned by institutional investors. Comparatively, 66.1% of Lyell Immunopharma shares are owned by institutional investors. 8.5% of Hyperliquid Strategies shares are owned by company insiders. Comparatively, 6.2% of Lyell Immunopharma shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

In the previous week, Lyell Immunopharma had 3 more articles in the media than Hyperliquid Strategies. MarketBeat recorded 6 mentions for Lyell Immunopharma and 3 mentions for Hyperliquid Strategies. Hyperliquid Strategies' average media sentiment score of 0.35 beat Lyell Immunopharma's score of 0.23 indicating that Hyperliquid Strategies is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Hyperliquid Strategies
0 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Lyell Immunopharma
1 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Hyperliquid Strategies presently has a consensus target price of $9.25, indicating a potential upside of 3.70%. Lyell Immunopharma has a consensus target price of $43.00, indicating a potential upside of 249.31%. Given Lyell Immunopharma's stronger consensus rating and higher possible upside, analysts clearly believe Lyell Immunopharma is more favorable than Hyperliquid Strategies.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Hyperliquid Strategies
1 Sell rating(s)
0 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.50
Lyell Immunopharma
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.67

Hyperliquid Strategies has a net margin of 0.00% compared to Lyell Immunopharma's net margin of -794,858.12%. Hyperliquid Strategies' return on equity of -56.04% beat Lyell Immunopharma's return on equity.

Company Net Margins Return on Equity Return on Assets
Hyperliquid StrategiesN/A -56.04% -52.22%
Lyell Immunopharma -794,858.12%-85.71%-66.41%

Summary

Hyperliquid Strategies beats Lyell Immunopharma on 9 of the 16 factors compared between the two stocks.

How does Lyell Immunopharma compare to Amylyx Pharmaceuticals?

Amylyx Pharmaceuticals (NASDAQ:AMLX) and Lyell Immunopharma (NASDAQ:LYEL) are both small-cap medical companies, but which is the better business? We will contrast the two companies based on the strength of their earnings, institutional ownership, profitability, dividends, analyst recommendations, risk, media sentiment and valuation.

Amylyx Pharmaceuticals has a net margin of 0.00% compared to Lyell Immunopharma's net margin of -794,858.12%. Amylyx Pharmaceuticals' return on equity of -55.69% beat Lyell Immunopharma's return on equity.

Company Net Margins Return on Equity Return on Assets
Amylyx PharmaceuticalsN/A -55.69% -50.73%
Lyell Immunopharma -794,858.12%-85.71%-66.41%

Amylyx Pharmaceuticals currently has a consensus price target of $23.00, indicating a potential upside of 76.79%. Lyell Immunopharma has a consensus price target of $43.00, indicating a potential upside of 249.31%. Given Lyell Immunopharma's higher possible upside, analysts plainly believe Lyell Immunopharma is more favorable than Amylyx Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Amylyx Pharmaceuticals
1 Sell rating(s)
2 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.75
Lyell Immunopharma
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.67

95.8% of Amylyx Pharmaceuticals shares are held by institutional investors. Comparatively, 66.1% of Lyell Immunopharma shares are held by institutional investors. 10.9% of Amylyx Pharmaceuticals shares are held by company insiders. Comparatively, 6.2% of Lyell Immunopharma shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Amylyx Pharmaceuticals has higher revenue and earnings than Lyell Immunopharma. Amylyx Pharmaceuticals is trading at a lower price-to-earnings ratio than Lyell Immunopharma, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Amylyx Pharmaceuticals$87.37M16.56-$144.74M-$1.50N/A
Lyell Immunopharma$31K9,265.86-$274.45M-$13.80N/A

In the previous week, Lyell Immunopharma had 2 more articles in the media than Amylyx Pharmaceuticals. MarketBeat recorded 6 mentions for Lyell Immunopharma and 4 mentions for Amylyx Pharmaceuticals. Lyell Immunopharma's average media sentiment score of 0.23 beat Amylyx Pharmaceuticals' score of 0.12 indicating that Lyell Immunopharma is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Amylyx Pharmaceuticals
0 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Lyell Immunopharma
1 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Amylyx Pharmaceuticals has a beta of -0.16, suggesting that its stock price is 116% less volatile than the broader market. Comparatively, Lyell Immunopharma has a beta of -0.09, suggesting that its stock price is 109% less volatile than the broader market.

Summary

Amylyx Pharmaceuticals beats Lyell Immunopharma on 10 of the 16 factors compared between the two stocks.

How does Lyell Immunopharma compare to AnaptysBio?

AnaptysBio (NASDAQ:ANAB) and Lyell Immunopharma (NASDAQ:LYEL) are both small-cap medical companies, but which is the better investment? We will contrast the two companies based on the strength of their institutional ownership, valuation, earnings, profitability, risk, analyst recommendations, dividends and media sentiment.

AnaptysBio presently has a consensus target price of $79.18, indicating a potential upside of 54.17%. Lyell Immunopharma has a consensus target price of $43.00, indicating a potential upside of 249.31%. Given Lyell Immunopharma's higher probable upside, analysts clearly believe Lyell Immunopharma is more favorable than AnaptysBio.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
AnaptysBio
1 Sell rating(s)
2 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.69
Lyell Immunopharma
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.67

AnaptysBio has a net margin of -11.53% compared to Lyell Immunopharma's net margin of -794,858.12%. Lyell Immunopharma's return on equity of -85.71% beat AnaptysBio's return on equity.

Company Net Margins Return on Equity Return on Assets
AnaptysBio-11.53% -1,101.24% -7.75%
Lyell Immunopharma -794,858.12%-85.71%-66.41%

66.1% of Lyell Immunopharma shares are held by institutional investors. 33.5% of AnaptysBio shares are held by company insiders. Comparatively, 6.2% of Lyell Immunopharma shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

In the previous week, Lyell Immunopharma had 4 more articles in the media than AnaptysBio. MarketBeat recorded 6 mentions for Lyell Immunopharma and 2 mentions for AnaptysBio. Lyell Immunopharma's average media sentiment score of 0.23 beat AnaptysBio's score of -0.82 indicating that Lyell Immunopharma is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
AnaptysBio
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Negative
Lyell Immunopharma
1 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

AnaptysBio has a beta of 0.72, suggesting that its share price is 28% less volatile than the broader market. Comparatively, Lyell Immunopharma has a beta of -0.09, suggesting that its share price is 109% less volatile than the broader market.

AnaptysBio has higher revenue and earnings than Lyell Immunopharma. AnaptysBio is trading at a lower price-to-earnings ratio than Lyell Immunopharma, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
AnaptysBio$234.60M6.37-$13.23M-$1.08N/A
Lyell Immunopharma$31K9,265.86-$274.45M-$13.80N/A

Summary

AnaptysBio beats Lyell Immunopharma on 9 of the 17 factors compared between the two stocks.

How does Lyell Immunopharma compare to Damora Therapeutics, Inc. Common Stock?

Damora Therapeutics, Inc. Common Stock (NASDAQ:DMRA) and Lyell Immunopharma (NASDAQ:LYEL) are both small-cap medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their valuation, institutional ownership, analyst recommendations, media sentiment, profitability, earnings, dividends and risk.

Damora Therapeutics, Inc. Common Stock has a net margin of 0.00% compared to Lyell Immunopharma's net margin of -794,858.12%. Lyell Immunopharma's return on equity of -85.71% beat Damora Therapeutics, Inc. Common Stock's return on equity.

Company Net Margins Return on Equity Return on Assets
Damora Therapeutics, Inc. Common StockN/A -428.30% -114.62%
Lyell Immunopharma -794,858.12%-85.71%-66.41%

Damora Therapeutics, Inc. Common Stock has higher earnings, but lower revenue than Lyell Immunopharma. Damora Therapeutics, Inc. Common Stock is trading at a lower price-to-earnings ratio than Lyell Immunopharma, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Damora Therapeutics, Inc. Common StockN/AN/A-$209.84M-$5.58N/A
Lyell Immunopharma$31K9,265.86-$274.45M-$13.80N/A

Damora Therapeutics, Inc. Common Stock has a beta of 1.46, meaning that its stock price is 46% more volatile than the broader market. Comparatively, Lyell Immunopharma has a beta of -0.09, meaning that its stock price is 109% less volatile than the broader market.

Damora Therapeutics, Inc. Common Stock currently has a consensus price target of $42.00, suggesting a potential upside of 100.86%. Lyell Immunopharma has a consensus price target of $43.00, suggesting a potential upside of 249.31%. Given Lyell Immunopharma's higher probable upside, analysts clearly believe Lyell Immunopharma is more favorable than Damora Therapeutics, Inc. Common Stock.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Damora Therapeutics, Inc. Common Stock
1 Sell rating(s)
1 Hold rating(s)
6 Buy rating(s)
2 Strong Buy rating(s)
2.90
Lyell Immunopharma
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.67

In the previous week, Lyell Immunopharma had 5 more articles in the media than Damora Therapeutics, Inc. Common Stock. MarketBeat recorded 6 mentions for Lyell Immunopharma and 1 mentions for Damora Therapeutics, Inc. Common Stock. Damora Therapeutics, Inc. Common Stock's average media sentiment score of 0.50 beat Lyell Immunopharma's score of 0.23 indicating that Damora Therapeutics, Inc. Common Stock is being referred to more favorably in the media.

Company Overall Sentiment
Damora Therapeutics, Inc. Common Stock Positive
Lyell Immunopharma Neutral

14.2% of Damora Therapeutics, Inc. Common Stock shares are held by institutional investors. Comparatively, 66.1% of Lyell Immunopharma shares are held by institutional investors. 0.4% of Damora Therapeutics, Inc. Common Stock shares are held by company insiders. Comparatively, 6.2% of Lyell Immunopharma shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

Summary

Damora Therapeutics, Inc. Common Stock and Lyell Immunopharma tied by winning 8 of the 16 factors compared between the two stocks.

How does Lyell Immunopharma compare to Vir Biotechnology?

Vir Biotechnology (NASDAQ:VIR) and Lyell Immunopharma (NASDAQ:LYEL) are both small-cap medical companies, but which is the better business? We will contrast the two companies based on the strength of their media sentiment, risk, profitability, earnings, dividends, analyst recommendations, valuation and institutional ownership.

Vir Biotechnology has a net margin of -638.88% compared to Lyell Immunopharma's net margin of -794,858.12%. Vir Biotechnology's return on equity of -53.31% beat Lyell Immunopharma's return on equity.

Company Net Margins Return on Equity Return on Assets
Vir Biotechnology-638.88% -53.31% -41.76%
Lyell Immunopharma -794,858.12%-85.71%-66.41%

65.3% of Vir Biotechnology shares are owned by institutional investors. Comparatively, 66.1% of Lyell Immunopharma shares are owned by institutional investors. 2.9% of Vir Biotechnology shares are owned by insiders. Comparatively, 6.2% of Lyell Immunopharma shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Vir Biotechnology currently has a consensus price target of $20.38, indicating a potential upside of 141.12%. Lyell Immunopharma has a consensus price target of $43.00, indicating a potential upside of 249.31%. Given Lyell Immunopharma's higher probable upside, analysts clearly believe Lyell Immunopharma is more favorable than Vir Biotechnology.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Vir Biotechnology
1 Sell rating(s)
0 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.89
Lyell Immunopharma
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.67

In the previous week, Vir Biotechnology had 4 more articles in the media than Lyell Immunopharma. MarketBeat recorded 10 mentions for Vir Biotechnology and 6 mentions for Lyell Immunopharma. Vir Biotechnology's average media sentiment score of 0.38 beat Lyell Immunopharma's score of 0.23 indicating that Vir Biotechnology is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Vir Biotechnology
2 Very Positive mention(s)
1 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Lyell Immunopharma
1 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Lyell Immunopharma has lower revenue, but higher earnings than Vir Biotechnology. Vir Biotechnology is trading at a lower price-to-earnings ratio than Lyell Immunopharma, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Vir Biotechnology$68.56M20.79-$437.99M-$3.13N/A
Lyell Immunopharma$31K9,265.86-$274.45M-$13.80N/A

Vir Biotechnology has a beta of 1.65, suggesting that its stock price is 65% more volatile than the broader market. Comparatively, Lyell Immunopharma has a beta of -0.09, suggesting that its stock price is 109% less volatile than the broader market.

Summary

Vir Biotechnology beats Lyell Immunopharma on 10 of the 16 factors compared between the two stocks.

Get Lyell Immunopharma News Delivered to You Automatically

Sign up to receive the latest news and ratings for LYEL and its competitors with MarketBeat's FREE daily newsletter.

Subscribe Now
SMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy.

New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding LYEL and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
Skip Chart

Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
Skip Chart

LYEL vs. The Competition

MetricLyell ImmunopharmaMED IndustryMedical SectorNASDAQ Exchange
Market Cap$279.31M$2.96B$6.48B$11.99B
Dividend YieldN/A1.70%2.67%5.58%
P/E Ratio-0.8917.6823.6923.74
Price / Sales9,265.86302.68514.83109.27
Price / CashN/A56.1726.9937.25
Price / Book1.053.8310.436.78
Net Income-$274.45M$75.85M$3.57B$337.51M
7 Day Performance-17.33%-2.00%0.27%-2.34%
1 Month Performance-36.32%-5.85%3.25%1.88%
1 Year Performance-1.28%14.03%22.24%25.55%

Lyell Immunopharma Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
LYEL
Lyell Immunopharma
2.9194 of 5 stars
$12.31
+2.8%
$43.00
+249.3%
-3.5%$279.31M$31KN/A270
PURR
Hyperliquid Strategies
1.6385 of 5 stars
$10.97
+0.9%
$9.25
-15.7%
N/A$1.57B$1MN/AN/A
AMLX
Amylyx Pharmaceuticals
2.622 of 5 stars
$13.29
-5.5%
$23.00
+73.1%
+144.1%$1.56B$87.37MN/A200
ANAB
AnaptysBio
2.7 of 5 stars
$51.26
-3.5%
$79.18
+54.5%
+116.7%$1.55B$234.60MN/A100
DMRA
Damora Therapeutics, Inc. Common Stock
2.7167 of 5 stars
$22.95
-7.6%
$42.00
+83.0%
+535.6%$1.53BN/AN/A40

Related Companies and Tools


This page (NASDAQ:LYEL) was last updated on 6/9/2026 by MarketBeat.com Staff.
From Our Partners