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Akebia Therapeutics (AKBA) Competitors

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$0.88 +0.01 (+1.70%)
Closing price 08/14/2026 04:00 PM Eastern
Extended Trading
$0.88 -0.01 (-0.95%)
As of 08/14/2026 07:55 PM Eastern
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AKBA vs. AVTX, SANA, JANX, OMER, and GERN

Should you buy Akebia Therapeutics stock or one of its competitors? Akebia Therapeutics's main competitors and comparable companies include Avalo Therapeutics (AVTX), Sana Biotechnology (SANA), Janux Therapeutics (JANX), Omeros (OMER), and Geron (GERN). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Akebia Therapeutics compare to Avalo Therapeutics?

Avalo Therapeutics (NASDAQ:AVTX) and Akebia Therapeutics (NASDAQ:AKBA) are both small-cap healthcare companies, but which is the superior stock? We will compare the two companies based on the strength of their earnings, institutional ownership, dividends, media sentiment, risk, valuation, profitability and analyst recommendations.

Avalo Therapeutics currently has a consensus target price of $45.10, indicating a potential upside of 130.22%. Akebia Therapeutics has a consensus target price of $3.75, indicating a potential upside of 324.02%. Given Akebia Therapeutics' higher probable upside, analysts clearly believe Akebia Therapeutics is more favorable than Avalo Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Avalo Therapeutics
1 Sell rating(s)
0 Hold rating(s)
13 Buy rating(s)
0 Strong Buy rating(s)
2.86
Akebia Therapeutics
1 Sell rating(s)
2 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.33

In the previous week, Avalo Therapeutics had 14 more articles in the media than Akebia Therapeutics. MarketBeat recorded 19 mentions for Avalo Therapeutics and 5 mentions for Akebia Therapeutics. Akebia Therapeutics' average media sentiment score of 0.18 beat Avalo Therapeutics' score of -0.10 indicating that Akebia Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Avalo Therapeutics
3 Very Positive mention(s)
3 Positive mention(s)
3 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
Akebia Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
1 Very Negative mention(s)
Neutral

Avalo Therapeutics has a beta of 0.8, suggesting that its share price is 20% less volatile than the broader market. Comparatively, Akebia Therapeutics has a beta of 0.26, suggesting that its share price is 74% less volatile than the broader market.

Avalo Therapeutics has a net margin of 0.00% compared to Akebia Therapeutics' net margin of -13.54%. Avalo Therapeutics' return on equity of -58.03% beat Akebia Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Avalo TherapeuticsN/A -58.03% -48.22%
Akebia Therapeutics -13.54%-88.88%-7.74%

87.1% of Avalo Therapeutics shares are owned by institutional investors. Comparatively, 33.9% of Akebia Therapeutics shares are owned by institutional investors. 4.5% of Avalo Therapeutics shares are owned by company insiders. Comparatively, 4.3% of Akebia Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

Akebia Therapeutics has higher revenue and earnings than Avalo Therapeutics. Akebia Therapeutics is trading at a lower price-to-earnings ratio than Avalo Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Avalo Therapeutics$60K17,510.20-$78.26M-$4.37N/A
Akebia Therapeutics$236.20M1.04-$5.34M-$0.11N/A

Summary

Avalo Therapeutics beats Akebia Therapeutics on 10 of the 16 factors compared between the two stocks.

How does Akebia Therapeutics compare to Sana Biotechnology?

Akebia Therapeutics (NASDAQ:AKBA) and Sana Biotechnology (NASDAQ:SANA) are both small-cap healthcare companies, but which is the superior investment? We will compare the two companies based on the strength of their dividends, analyst recommendations, risk, earnings, profitability, institutional ownership, media sentiment and valuation.

In the previous week, Sana Biotechnology had 14 more articles in the media than Akebia Therapeutics. MarketBeat recorded 19 mentions for Sana Biotechnology and 5 mentions for Akebia Therapeutics. Akebia Therapeutics' average media sentiment score of 0.18 beat Sana Biotechnology's score of 0.05 indicating that Akebia Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Akebia Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
1 Very Negative mention(s)
Neutral
Sana Biotechnology
1 Very Positive mention(s)
3 Positive mention(s)
3 Neutral mention(s)
2 Negative mention(s)
1 Very Negative mention(s)
Neutral

Akebia Therapeutics has higher revenue and earnings than Sana Biotechnology. Akebia Therapeutics is trading at a lower price-to-earnings ratio than Sana Biotechnology, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Akebia Therapeutics$236.20M1.04-$5.34M-$0.11N/A
Sana BiotechnologyN/AN/A-$244.17M-$0.76N/A

Sana Biotechnology has a net margin of 0.00% compared to Akebia Therapeutics' net margin of -13.54%. Akebia Therapeutics' return on equity of -88.88% beat Sana Biotechnology's return on equity.

Company Net Margins Return on Equity Return on Assets
Akebia Therapeutics-13.54% -88.88% -7.74%
Sana Biotechnology N/A -103.02%-39.16%

Akebia Therapeutics presently has a consensus price target of $3.75, indicating a potential upside of 324.02%. Sana Biotechnology has a consensus price target of $9.33, indicating a potential upside of 162.91%. Given Akebia Therapeutics' higher possible upside, research analysts plainly believe Akebia Therapeutics is more favorable than Sana Biotechnology.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Akebia Therapeutics
1 Sell rating(s)
2 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.33
Sana Biotechnology
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.67

Akebia Therapeutics has a beta of 0.26, suggesting that its share price is 74% less volatile than the broader market. Comparatively, Sana Biotechnology has a beta of 2.16, suggesting that its share price is 116% more volatile than the broader market.

33.9% of Akebia Therapeutics shares are owned by institutional investors. Comparatively, 88.2% of Sana Biotechnology shares are owned by institutional investors. 4.3% of Akebia Therapeutics shares are owned by insiders. Comparatively, 25.4% of Sana Biotechnology shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

Summary

Sana Biotechnology beats Akebia Therapeutics on 8 of the 15 factors compared between the two stocks.

How does Akebia Therapeutics compare to Janux Therapeutics?

Janux Therapeutics (NASDAQ:JANX) and Akebia Therapeutics (NASDAQ:AKBA) are both small-cap healthcare companies, but which is the better stock? We will compare the two businesses based on the strength of their analyst recommendations, profitability, earnings, dividends, media sentiment, valuation, risk and institutional ownership.

Janux Therapeutics presently has a consensus target price of $37.58, suggesting a potential upside of 133.15%. Akebia Therapeutics has a consensus target price of $3.75, suggesting a potential upside of 324.02%. Given Akebia Therapeutics' higher possible upside, analysts clearly believe Akebia Therapeutics is more favorable than Janux Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Janux Therapeutics
2 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.50
Akebia Therapeutics
1 Sell rating(s)
2 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.33

Janux Therapeutics has a net margin of 0.00% compared to Akebia Therapeutics' net margin of -13.54%. Janux Therapeutics' return on equity of -11.89% beat Akebia Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Janux TherapeuticsN/A -11.89% -11.13%
Akebia Therapeutics -13.54%-88.88%-7.74%

75.4% of Janux Therapeutics shares are held by institutional investors. Comparatively, 33.9% of Akebia Therapeutics shares are held by institutional investors. 7.9% of Janux Therapeutics shares are held by insiders. Comparatively, 4.3% of Akebia Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

Akebia Therapeutics has higher revenue and earnings than Janux Therapeutics. Janux Therapeutics is trading at a lower price-to-earnings ratio than Akebia Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Janux Therapeutics$24M41.06-$113.62M-$1.64N/A
Akebia Therapeutics$236.20M1.04-$5.34M-$0.11N/A

In the previous week, Janux Therapeutics had 16 more articles in the media than Akebia Therapeutics. MarketBeat recorded 21 mentions for Janux Therapeutics and 5 mentions for Akebia Therapeutics. Janux Therapeutics' average media sentiment score of 0.47 beat Akebia Therapeutics' score of 0.18 indicating that Janux Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Janux Therapeutics
2 Very Positive mention(s)
4 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
Akebia Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
1 Very Negative mention(s)
Neutral

Janux Therapeutics has a beta of 2.5, indicating that its stock price is 150% more volatile than the broader market. Comparatively, Akebia Therapeutics has a beta of 0.26, indicating that its stock price is 74% less volatile than the broader market.

Summary

Janux Therapeutics beats Akebia Therapeutics on 10 of the 16 factors compared between the two stocks.

How does Akebia Therapeutics compare to Omeros?

Akebia Therapeutics (NASDAQ:AKBA) and Omeros (NASDAQ:OMER) are both small-cap healthcare companies, but which is the superior investment? We will contrast the two businesses based on the strength of their earnings, institutional ownership, media sentiment, profitability, valuation, dividends, analyst recommendations and risk.

In the previous week, Omeros had 28 more articles in the media than Akebia Therapeutics. MarketBeat recorded 33 mentions for Omeros and 5 mentions for Akebia Therapeutics. Omeros' average media sentiment score of 0.52 beat Akebia Therapeutics' score of 0.18 indicating that Omeros is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Akebia Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
1 Very Negative mention(s)
Neutral
Omeros
6 Very Positive mention(s)
3 Positive mention(s)
12 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Positive

Omeros has lower revenue, but higher earnings than Akebia Therapeutics. Akebia Therapeutics is trading at a lower price-to-earnings ratio than Omeros, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Akebia Therapeutics$236.20M1.04-$5.34M-$0.11N/A
OmerosN/AN/A-$3.35M$1.2813.43

Akebia Therapeutics presently has a consensus target price of $3.75, suggesting a potential upside of 324.02%. Omeros has a consensus target price of $38.00, suggesting a potential upside of 121.06%. Given Akebia Therapeutics' higher possible upside, analysts plainly believe Akebia Therapeutics is more favorable than Omeros.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Akebia Therapeutics
1 Sell rating(s)
2 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.33
Omeros
0 Sell rating(s)
3 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
2.67

33.9% of Akebia Therapeutics shares are owned by institutional investors. Comparatively, 48.8% of Omeros shares are owned by institutional investors. 4.3% of Akebia Therapeutics shares are owned by insiders. Comparatively, 10.5% of Omeros shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.

Akebia Therapeutics has a beta of 0.26, meaning that its share price is 74% less volatile than the broader market. Comparatively, Omeros has a beta of 2.54, meaning that its share price is 154% more volatile than the broader market.

Omeros has a net margin of 0.00% compared to Akebia Therapeutics' net margin of -13.54%. Akebia Therapeutics' return on equity of -88.88% beat Omeros' return on equity.

Company Net Margins Return on Equity Return on Assets
Akebia Therapeutics-13.54% -88.88% -7.74%
Omeros N/A -164.92%69.41%

Summary

Omeros beats Akebia Therapeutics on 12 of the 16 factors compared between the two stocks.

How does Akebia Therapeutics compare to Geron?

Akebia Therapeutics (NASDAQ:AKBA) and Geron (NASDAQ:GERN) are both small-cap healthcare companies, but which is the better investment? We will compare the two companies based on the strength of their institutional ownership, valuation, media sentiment, risk, analyst recommendations, earnings, dividends and profitability.

Akebia Therapeutics has a beta of 0.26, indicating that its stock price is 74% less volatile than the broader market. Comparatively, Geron has a beta of 0.61, indicating that its stock price is 39% less volatile than the broader market.

Akebia Therapeutics has a net margin of -13.54% compared to Geron's net margin of -34.17%. Geron's return on equity of -24.48% beat Akebia Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Akebia Therapeutics-13.54% -88.88% -7.74%
Geron -34.17%-24.48%-10.30%

Akebia Therapeutics presently has a consensus price target of $3.75, indicating a potential upside of 324.02%. Geron has a consensus price target of $4.00, indicating a potential upside of 172.11%. Given Akebia Therapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Akebia Therapeutics is more favorable than Geron.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Akebia Therapeutics
1 Sell rating(s)
2 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.33
Geron
1 Sell rating(s)
2 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.20

In the previous week, Geron had 1 more articles in the media than Akebia Therapeutics. MarketBeat recorded 6 mentions for Geron and 5 mentions for Akebia Therapeutics. Geron's average media sentiment score of 0.72 beat Akebia Therapeutics' score of 0.18 indicating that Geron is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Akebia Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
1 Very Negative mention(s)
Neutral
Geron
2 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Akebia Therapeutics has higher revenue and earnings than Geron. Geron is trading at a lower price-to-earnings ratio than Akebia Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Akebia Therapeutics$236.20M1.04-$5.34M-$0.11N/A
Geron$183.88M5.14-$83.50M-$0.11N/A

33.9% of Akebia Therapeutics shares are owned by institutional investors. Comparatively, 73.7% of Geron shares are owned by institutional investors. 4.3% of Akebia Therapeutics shares are owned by company insiders. Comparatively, 1.7% of Geron shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Summary

Akebia Therapeutics beats Geron on 9 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding AKBA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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AKBA vs. The Competition

MetricAkebia TherapeuticsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$241.86M$3.72B$7.03B$13.07B
Dividend YieldN/A3.69%2.57%10.65%
P/E Ratio-8.0410.77271.2625.40
Price / Sales1.041,367.37623.44105.59
Price / CashN/A101.4275.7053.27
Price / Book9.8316.7812.926.21
Net Income-$5.34M-$13.32M$3.45B$347.71M
7 Day Performance-2.80%1.76%1.16%1.08%
1 Month Performance-36.83%2.86%2.17%1.87%
1 Year Performance-72.79%54.10%62.38%20.79%

Akebia Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
AKBA
Akebia Therapeutics
2.0154 of 5 stars
$0.88
+1.7%
$3.75
+324.0%
-72.8%$241.86M$236.20MN/A430
AVTX
Avalo Therapeutics
2.5146 of 5 stars
$19.77
+7.9%
$45.10
+128.1%
+117.2%$982.50M$60KN/A40
SANA
Sana Biotechnology
1.7678 of 5 stars
$3.61
+2.6%
$9.50
+163.2%
+6.6%$979.59MN/AN/A380
JANX
Janux Therapeutics
2.6793 of 5 stars
$16.41
+3.5%
$37.58
+129.0%
-35.8%$969.02M$10MN/A30
OMER
Omeros
3.6685 of 5 stars
$13.62
+2.8%
$38.00
+179.0%
+289.8%$958.97MN/A19.46210

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This page (NASDAQ:AKBA) was last updated on 8/16/2026 by MarketBeat.com Staff.
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