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Akebia Therapeutics (AKBA) Competitors

Akebia Therapeutics logo
$0.97 -0.01 (-0.87%)
As of 09/4/2026 04:00 PM Eastern

AKBA vs. GERN, DSGN, ANNX, OLMA, and ANL

Should you buy Akebia Therapeutics stock or one of its competitors? Akebia Therapeutics's main competitors and comparable companies include Geron (GERN), Design Therapeutics (DSGN), Annexon (ANNX), Olema Pharmaceuticals (OLMA), and Adlai Nortye (ANL). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Akebia Therapeutics compare to Geron?

Akebia Therapeutics (NASDAQ:AKBA) and Geron (NASDAQ:GERN) are both small-cap healthcare companies, but which is the superior business? We will compare the two businesses based on the strength of their institutional ownership, earnings, dividends, profitability, valuation, risk, media sentiment and analyst recommendations.

In the previous week, Geron had 5 more articles in the media than Akebia Therapeutics. MarketBeat recorded 8 mentions for Geron and 3 mentions for Akebia Therapeutics. Geron's average media sentiment score of 0.74 beat Akebia Therapeutics' score of 0.68 indicating that Geron is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Akebia Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Geron
3 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Akebia Therapeutics has higher revenue and earnings than Geron. Geron is trading at a lower price-to-earnings ratio than Akebia Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Akebia Therapeutics$236.20M1.14-$5.34M-$0.11N/A
Geron$183.88M5.49-$83.50M-$0.11N/A

Akebia Therapeutics presently has a consensus price target of $3.75, suggesting a potential upside of 284.73%. Geron has a consensus price target of $4.00, suggesting a potential upside of 154.78%. Given Akebia Therapeutics' stronger consensus rating and higher possible upside, equities research analysts plainly believe Akebia Therapeutics is more favorable than Geron.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Akebia Therapeutics
1 Sell rating(s)
2 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.33
Geron
1 Sell rating(s)
2 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.20

33.9% of Akebia Therapeutics shares are held by institutional investors. Comparatively, 73.7% of Geron shares are held by institutional investors. 4.3% of Akebia Therapeutics shares are held by insiders. Comparatively, 1.7% of Geron shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Akebia Therapeutics has a net margin of -13.54% compared to Geron's net margin of -34.17%. Geron's return on equity of -24.48% beat Akebia Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Akebia Therapeutics-13.54% -88.88% -7.74%
Geron -34.17%-24.48%-10.30%

Akebia Therapeutics has a beta of 0.19, indicating that its share price is 81% less volatile than the broader market. Comparatively, Geron has a beta of 0.61, indicating that its share price is 39% less volatile than the broader market.

Summary

Akebia Therapeutics beats Geron on 9 of the 15 factors compared between the two stocks.

How does Akebia Therapeutics compare to Design Therapeutics?

Design Therapeutics (NASDAQ:DSGN) and Akebia Therapeutics (NASDAQ:AKBA) are both small-cap healthcare companies, but which is the better investment? We will compare the two companies based on the strength of their profitability, earnings, risk, analyst recommendations, institutional ownership, dividends, media sentiment and valuation.

Design Therapeutics has a beta of 1.66, indicating that its stock price is 66% more volatile than the broader market. Comparatively, Akebia Therapeutics has a beta of 0.19, indicating that its stock price is 81% less volatile than the broader market.

Design Therapeutics has a net margin of 0.00% compared to Akebia Therapeutics' net margin of -13.54%. Design Therapeutics' return on equity of -34.03% beat Akebia Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Design TherapeuticsN/A -34.03% -32.05%
Akebia Therapeutics -13.54%-88.88%-7.74%

56.6% of Design Therapeutics shares are held by institutional investors. Comparatively, 33.9% of Akebia Therapeutics shares are held by institutional investors. 17.1% of Design Therapeutics shares are held by insiders. Comparatively, 4.3% of Akebia Therapeutics shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

In the previous week, Design Therapeutics had 1 more articles in the media than Akebia Therapeutics. MarketBeat recorded 4 mentions for Design Therapeutics and 3 mentions for Akebia Therapeutics. Design Therapeutics' average media sentiment score of 0.85 beat Akebia Therapeutics' score of 0.68 indicating that Design Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Design Therapeutics
2 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Akebia Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Akebia Therapeutics has higher revenue and earnings than Design Therapeutics. Design Therapeutics is trading at a lower price-to-earnings ratio than Akebia Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Design TherapeuticsN/AN/A-$69.79M-$1.18N/A
Akebia Therapeutics$236.20M1.14-$5.34M-$0.11N/A

Design Therapeutics presently has a consensus target price of $16.50, indicating a potential upside of 8.98%. Akebia Therapeutics has a consensus target price of $3.75, indicating a potential upside of 284.73%. Given Akebia Therapeutics' higher possible upside, analysts clearly believe Akebia Therapeutics is more favorable than Design Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Design Therapeutics
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.88
Akebia Therapeutics
1 Sell rating(s)
2 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.33

Summary

Design Therapeutics beats Akebia Therapeutics on 10 of the 16 factors compared between the two stocks.

How does Akebia Therapeutics compare to Annexon?

Annexon (NASDAQ:ANNX) and Akebia Therapeutics (NASDAQ:AKBA) are both small-cap healthcare companies, but which is the superior stock? We will contrast the two businesses based on the strength of their valuation, media sentiment, earnings, institutional ownership, profitability, risk, dividends and analyst recommendations.

Akebia Therapeutics has higher revenue and earnings than Annexon. Akebia Therapeutics is trading at a lower price-to-earnings ratio than Annexon, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
AnnexonN/AN/A-$206.69M-$1.16N/A
Akebia Therapeutics$236.20M1.14-$5.34M-$0.11N/A

Annexon has a beta of 1.21, suggesting that its share price is 21% more volatile than the broader market. Comparatively, Akebia Therapeutics has a beta of 0.19, suggesting that its share price is 81% less volatile than the broader market.

Annexon has a net margin of 0.00% compared to Akebia Therapeutics' net margin of -13.54%. Akebia Therapeutics' return on equity of -88.88% beat Annexon's return on equity.

Company Net Margins Return on Equity Return on Assets
AnnexonN/A -106.15% -79.82%
Akebia Therapeutics -13.54%-88.88%-7.74%

In the previous week, Annexon had 4 more articles in the media than Akebia Therapeutics. MarketBeat recorded 7 mentions for Annexon and 3 mentions for Akebia Therapeutics. Annexon's average media sentiment score of 0.78 beat Akebia Therapeutics' score of 0.68 indicating that Annexon is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Annexon
2 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Akebia Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Annexon presently has a consensus target price of $15.14, indicating a potential upside of 210.94%. Akebia Therapeutics has a consensus target price of $3.75, indicating a potential upside of 284.73%. Given Akebia Therapeutics' higher possible upside, analysts clearly believe Akebia Therapeutics is more favorable than Annexon.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Annexon
2 Sell rating(s)
2 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.40
Akebia Therapeutics
1 Sell rating(s)
2 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.33

33.9% of Akebia Therapeutics shares are owned by institutional investors. 10.3% of Annexon shares are owned by company insiders. Comparatively, 4.3% of Akebia Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Summary

Annexon beats Akebia Therapeutics on 8 of the 15 factors compared between the two stocks.

How does Akebia Therapeutics compare to Olema Pharmaceuticals?

Olema Pharmaceuticals (NASDAQ:OLMA) and Akebia Therapeutics (NASDAQ:AKBA) are both small-cap healthcare companies, but which is the superior investment? We will contrast the two companies based on the strength of their analyst recommendations, media sentiment, institutional ownership, valuation, earnings, risk, profitability and dividends.

Akebia Therapeutics has higher revenue and earnings than Olema Pharmaceuticals. Akebia Therapeutics is trading at a lower price-to-earnings ratio than Olema Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Olema PharmaceuticalsN/AN/A-$162.45M-$2.12N/A
Akebia Therapeutics$236.20M1.14-$5.34M-$0.11N/A

Olema Pharmaceuticals currently has a consensus price target of $42.40, indicating a potential upside of 294.42%. Akebia Therapeutics has a consensus price target of $3.75, indicating a potential upside of 284.73%. Given Olema Pharmaceuticals' stronger consensus rating and higher probable upside, equities research analysts plainly believe Olema Pharmaceuticals is more favorable than Akebia Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Olema Pharmaceuticals
1 Sell rating(s)
2 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.71
Akebia Therapeutics
1 Sell rating(s)
2 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.33

Olema Pharmaceuticals has a beta of 1.98, indicating that its share price is 98% more volatile than the broader market. Comparatively, Akebia Therapeutics has a beta of 0.19, indicating that its share price is 81% less volatile than the broader market.

In the previous week, Olema Pharmaceuticals had 2 more articles in the media than Akebia Therapeutics. MarketBeat recorded 5 mentions for Olema Pharmaceuticals and 3 mentions for Akebia Therapeutics. Olema Pharmaceuticals' average media sentiment score of 0.73 beat Akebia Therapeutics' score of 0.68 indicating that Olema Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Olema Pharmaceuticals
2 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Akebia Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Olema Pharmaceuticals has a net margin of 0.00% compared to Akebia Therapeutics' net margin of -13.54%. Olema Pharmaceuticals' return on equity of -48.26% beat Akebia Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Olema PharmaceuticalsN/A -48.26% -43.04%
Akebia Therapeutics -13.54%-88.88%-7.74%

91.8% of Olema Pharmaceuticals shares are owned by institutional investors. Comparatively, 33.9% of Akebia Therapeutics shares are owned by institutional investors. 12.6% of Olema Pharmaceuticals shares are owned by insiders. Comparatively, 4.3% of Akebia Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Summary

Olema Pharmaceuticals beats Akebia Therapeutics on 11 of the 15 factors compared between the two stocks.

How does Akebia Therapeutics compare to Adlai Nortye?

Akebia Therapeutics (NASDAQ:AKBA) and Adlai Nortye (NASDAQ:ANL) are both small-cap healthcare companies, but which is the superior business? We will contrast the two businesses based on the strength of their valuation, media sentiment, profitability, analyst recommendations, institutional ownership, earnings, dividends and risk.

Akebia Therapeutics has higher revenue and earnings than Adlai Nortye.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Akebia Therapeutics$236.20M1.14-$5.34M-$0.11N/A
Adlai Nortye$18.06M53.53-$35.53MN/AN/A

In the previous week, Akebia Therapeutics and Akebia Therapeutics both had 3 articles in the media. Adlai Nortye's average media sentiment score of 0.80 beat Akebia Therapeutics' score of 0.68 indicating that Adlai Nortye is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Akebia Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Adlai Nortye
2 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Adlai Nortye has a net margin of 0.00% compared to Akebia Therapeutics' net margin of -13.54%. Adlai Nortye's return on equity of 0.00% beat Akebia Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Akebia Therapeutics-13.54% -88.88% -7.74%
Adlai Nortye N/A N/A N/A

Akebia Therapeutics currently has a consensus target price of $3.75, suggesting a potential upside of 284.73%. Adlai Nortye has a consensus target price of $24.25, suggesting a potential upside of 61.56%. Given Akebia Therapeutics' higher probable upside, research analysts plainly believe Akebia Therapeutics is more favorable than Adlai Nortye.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Akebia Therapeutics
1 Sell rating(s)
2 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.33
Adlai Nortye
1 Sell rating(s)
0 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.67

33.9% of Akebia Therapeutics shares are held by institutional investors. Comparatively, 35.2% of Adlai Nortye shares are held by institutional investors. 4.3% of Akebia Therapeutics shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

Akebia Therapeutics has a beta of 0.19, indicating that its share price is 81% less volatile than the broader market. Comparatively, Adlai Nortye has a beta of 1.04, indicating that its share price is 4% more volatile than the broader market.

Summary

Adlai Nortye beats Akebia Therapeutics on 9 of the 13 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding AKBA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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AKBA vs. The Competition

MetricAkebia TherapeuticsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$272.48M$4.02B$7.27B$12.91B
Dividend YieldN/A3.60%2.53%8.90%
P/E Ratio-8.8612.65272.4325.42
Price / Sales1.141,243.68594.0275.77
Price / CashN/A107.4077.3952.28
Price / Book10.8316.1512.856.17
Net Income-$5.34M-$22.76M$3.48B$349.50M
7 Day Performance10.94%0.30%0.99%-0.15%
1 Month Performance-24.44%8.24%5.49%1.02%
1 Year Performance-67.07%49.08%24.34%14.50%

Akebia Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
AKBA
Akebia Therapeutics
2.3606 of 5 stars
$0.97
-0.9%
$3.75
+284.7%
-67.7%$272.48M$236.20MN/A430
GERN
Geron
1.9121 of 5 stars
$1.49
-1.3%
$4.00
+168.5%
+13.8%$970.14M$183.88MN/A70
DSGN
Design Therapeutics
1.1525 of 5 stars
$15.09
-0.1%
$16.50
+9.3%
+147.8%$945.61MN/AN/A40
ANNX
Annexon
2.0926 of 5 stars
$4.94
-0.6%
$15.33
+210.4%
+126.5%$942.21MN/AN/A60
OLMA
Olema Pharmaceuticals
2.2316 of 5 stars
$10.43
+1.6%
$42.40
+306.5%
+69.3%$898.60MN/AN/A70

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This page (NASDAQ:AKBA) was last updated on 9/5/2026 by MarketBeat.com Staff.
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