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Ultragenyx Pharmaceutical (RARE) Competitors

Ultragenyx Pharmaceutical logo
$25.72 -0.11 (-0.43%)
Closing price 04:00 PM Eastern
Extended Trading
$25.84 +0.12 (+0.47%)
As of 07:24 PM Eastern
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RARE vs. ABVX, PRAX, PTGX, KRYS, and NUVL

Should you buy Ultragenyx Pharmaceutical stock or one of its competitors? Ultragenyx Pharmaceutical's main competitors and comparable companies include Abivax (ABVX), Praxis Precision Medicines (PRAX), Protagonist Therapeutics (PTGX), Krystal Biotech (KRYS), and Nuvalent (NUVL). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Ultragenyx Pharmaceutical compare to Abivax?

Abivax (NASDAQ:ABVX) and Ultragenyx Pharmaceutical (NASDAQ:RARE) are both healthcare companies, but which is the better investment? We will compare the two businesses based on the strength of their risk, valuation, institutional ownership, analyst recommendations, earnings, profitability, media sentiment and dividends.

Abivax has a net margin of 0.00% compared to Ultragenyx Pharmaceutical's net margin of -81.79%. Abivax's return on equity of -99.02% beat Ultragenyx Pharmaceutical's return on equity.

Company Net Margins Return on Equity Return on Assets
AbivaxN/A -99.02% -70.26%
Ultragenyx Pharmaceutical -81.79%-1,024.42%-44.40%

Abivax has a beta of 1.03, meaning that its stock price is 3% more volatile than the broader market. Comparatively, Ultragenyx Pharmaceutical has a beta of 0.35, meaning that its stock price is 65% less volatile than the broader market.

In the previous week, Ultragenyx Pharmaceutical had 31 more articles in the media than Abivax. MarketBeat recorded 32 mentions for Ultragenyx Pharmaceutical and 1 mentions for Abivax. Abivax's average media sentiment score of 1.76 beat Ultragenyx Pharmaceutical's score of 0.98 indicating that Abivax is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Abivax
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive
Ultragenyx Pharmaceutical
20 Very Positive mention(s)
0 Positive mention(s)
6 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Abivax presently has a consensus target price of $156.50, suggesting a potential upside of 34.74%. Ultragenyx Pharmaceutical has a consensus target price of $58.89, suggesting a potential upside of 128.96%. Given Ultragenyx Pharmaceutical's stronger consensus rating and higher possible upside, analysts clearly believe Ultragenyx Pharmaceutical is more favorable than Abivax.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Abivax
1 Sell rating(s)
1 Hold rating(s)
13 Buy rating(s)
0 Strong Buy rating(s)
2.80
Ultragenyx Pharmaceutical
1 Sell rating(s)
2 Hold rating(s)
15 Buy rating(s)
1 Strong Buy rating(s)
2.84

Abivax has higher earnings, but lower revenue than Ultragenyx Pharmaceutical. Abivax is trading at a lower price-to-earnings ratio than Ultragenyx Pharmaceutical, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
AbivaxN/AN/A-$380.27M-$5.21N/A
Ultragenyx Pharmaceutical$673M3.77-$575M-$5.84N/A

47.9% of Abivax shares are held by institutional investors. Comparatively, 97.7% of Ultragenyx Pharmaceutical shares are held by institutional investors. 5.2% of Ultragenyx Pharmaceutical shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

Summary

Ultragenyx Pharmaceutical beats Abivax on 10 of the 16 factors compared between the two stocks.

How does Ultragenyx Pharmaceutical compare to Praxis Precision Medicines?

Praxis Precision Medicines (NASDAQ:PRAX) and Ultragenyx Pharmaceutical (NASDAQ:RARE) are both healthcare companies, but which is the superior investment? We will contrast the two companies based on the strength of their profitability, analyst recommendations, media sentiment, earnings, institutional ownership, dividends, valuation and risk.

Praxis Precision Medicines has a net margin of 0.00% compared to Ultragenyx Pharmaceutical's net margin of -81.79%. Praxis Precision Medicines' return on equity of -34.15% beat Ultragenyx Pharmaceutical's return on equity.

Company Net Margins Return on Equity Return on Assets
Praxis Precision MedicinesN/A -34.15% -32.42%
Ultragenyx Pharmaceutical -81.79%-1,024.42%-44.40%

In the previous week, Ultragenyx Pharmaceutical had 29 more articles in the media than Praxis Precision Medicines. MarketBeat recorded 32 mentions for Ultragenyx Pharmaceutical and 3 mentions for Praxis Precision Medicines. Ultragenyx Pharmaceutical's average media sentiment score of 0.98 beat Praxis Precision Medicines' score of 0.36 indicating that Ultragenyx Pharmaceutical is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Praxis Precision Medicines
1 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Ultragenyx Pharmaceutical
20 Very Positive mention(s)
0 Positive mention(s)
6 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Praxis Precision Medicines has higher earnings, but lower revenue than Ultragenyx Pharmaceutical. Praxis Precision Medicines is trading at a lower price-to-earnings ratio than Ultragenyx Pharmaceutical, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Praxis Precision Medicines$8.55M1,201.80-$303.27M-$12.93N/A
Ultragenyx Pharmaceutical$673M3.77-$575M-$5.84N/A

67.8% of Praxis Precision Medicines shares are owned by institutional investors. Comparatively, 97.7% of Ultragenyx Pharmaceutical shares are owned by institutional investors. 3.0% of Praxis Precision Medicines shares are owned by company insiders. Comparatively, 5.2% of Ultragenyx Pharmaceutical shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

Praxis Precision Medicines has a beta of 2.78, suggesting that its share price is 178% more volatile than the broader market. Comparatively, Ultragenyx Pharmaceutical has a beta of 0.35, suggesting that its share price is 65% less volatile than the broader market.

Praxis Precision Medicines presently has a consensus target price of $585.95, indicating a potential upside of 59.21%. Ultragenyx Pharmaceutical has a consensus target price of $58.89, indicating a potential upside of 128.96%. Given Ultragenyx Pharmaceutical's higher probable upside, analysts plainly believe Ultragenyx Pharmaceutical is more favorable than Praxis Precision Medicines.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Praxis Precision Medicines
2 Sell rating(s)
0 Hold rating(s)
16 Buy rating(s)
4 Strong Buy rating(s)
3.00
Ultragenyx Pharmaceutical
1 Sell rating(s)
2 Hold rating(s)
15 Buy rating(s)
1 Strong Buy rating(s)
2.84

Summary

Praxis Precision Medicines beats Ultragenyx Pharmaceutical on 9 of the 17 factors compared between the two stocks.

How does Ultragenyx Pharmaceutical compare to Protagonist Therapeutics?

Ultragenyx Pharmaceutical (NASDAQ:RARE) and Protagonist Therapeutics (NASDAQ:PTGX) are both mid-cap healthcare companies, but which is the better investment? We will compare the two businesses based on the strength of their profitability, analyst recommendations, valuation, media sentiment, institutional ownership, risk, earnings and dividends.

Protagonist Therapeutics has a net margin of 29.40% compared to Ultragenyx Pharmaceutical's net margin of -81.79%. Protagonist Therapeutics' return on equity of 12.03% beat Ultragenyx Pharmaceutical's return on equity.

Company Net Margins Return on Equity Return on Assets
Ultragenyx Pharmaceutical-81.79% -1,024.42% -44.40%
Protagonist Therapeutics 29.40%12.03%11.23%

In the previous week, Ultragenyx Pharmaceutical had 23 more articles in the media than Protagonist Therapeutics. MarketBeat recorded 32 mentions for Ultragenyx Pharmaceutical and 9 mentions for Protagonist Therapeutics. Ultragenyx Pharmaceutical's average media sentiment score of 0.98 beat Protagonist Therapeutics' score of 0.95 indicating that Ultragenyx Pharmaceutical is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Ultragenyx Pharmaceutical
20 Very Positive mention(s)
0 Positive mention(s)
6 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Protagonist Therapeutics
6 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Protagonist Therapeutics has lower revenue, but higher earnings than Ultragenyx Pharmaceutical. Ultragenyx Pharmaceutical is trading at a lower price-to-earnings ratio than Protagonist Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Ultragenyx Pharmaceutical$673M3.77-$575M-$5.84N/A
Protagonist Therapeutics$46.02M217.56-$130.15M$1.03150.21

97.7% of Ultragenyx Pharmaceutical shares are held by institutional investors. Comparatively, 98.6% of Protagonist Therapeutics shares are held by institutional investors. 5.2% of Ultragenyx Pharmaceutical shares are held by insiders. Comparatively, 5.2% of Protagonist Therapeutics shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

Ultragenyx Pharmaceutical presently has a consensus target price of $58.89, suggesting a potential upside of 128.96%. Protagonist Therapeutics has a consensus target price of $140.53, suggesting a potential downside of 9.17%. Given Ultragenyx Pharmaceutical's higher possible upside, analysts plainly believe Ultragenyx Pharmaceutical is more favorable than Protagonist Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Ultragenyx Pharmaceutical
1 Sell rating(s)
2 Hold rating(s)
15 Buy rating(s)
1 Strong Buy rating(s)
2.84
Protagonist Therapeutics
0 Sell rating(s)
2 Hold rating(s)
15 Buy rating(s)
1 Strong Buy rating(s)
2.94

Ultragenyx Pharmaceutical has a beta of 0.35, suggesting that its stock price is 65% less volatile than the broader market. Comparatively, Protagonist Therapeutics has a beta of 1.78, suggesting that its stock price is 78% more volatile than the broader market.

Summary

Protagonist Therapeutics beats Ultragenyx Pharmaceutical on 10 of the 15 factors compared between the two stocks.

How does Ultragenyx Pharmaceutical compare to Krystal Biotech?

Krystal Biotech (NASDAQ:KRYS) and Ultragenyx Pharmaceutical (NASDAQ:RARE) are both healthcare companies, but which is the superior stock? We will compare the two companies based on the strength of their analyst recommendations, risk, valuation, dividends, media sentiment, profitability, earnings and institutional ownership.

Krystal Biotech has higher earnings, but lower revenue than Ultragenyx Pharmaceutical. Ultragenyx Pharmaceutical is trading at a lower price-to-earnings ratio than Krystal Biotech, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Krystal Biotech$389.13M25.99$204.83M$7.9842.82
Ultragenyx Pharmaceutical$673M3.77-$575M-$5.84N/A

86.3% of Krystal Biotech shares are held by institutional investors. Comparatively, 97.7% of Ultragenyx Pharmaceutical shares are held by institutional investors. 13.1% of Krystal Biotech shares are held by insiders. Comparatively, 5.2% of Ultragenyx Pharmaceutical shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Krystal Biotech has a beta of 0.53, indicating that its stock price is 47% less volatile than the broader market. Comparatively, Ultragenyx Pharmaceutical has a beta of 0.35, indicating that its stock price is 65% less volatile than the broader market.

In the previous week, Ultragenyx Pharmaceutical had 25 more articles in the media than Krystal Biotech. MarketBeat recorded 32 mentions for Ultragenyx Pharmaceutical and 7 mentions for Krystal Biotech. Krystal Biotech's average media sentiment score of 1.26 beat Ultragenyx Pharmaceutical's score of 0.98 indicating that Krystal Biotech is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Krystal Biotech
7 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Ultragenyx Pharmaceutical
20 Very Positive mention(s)
0 Positive mention(s)
6 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Krystal Biotech has a net margin of 54.82% compared to Ultragenyx Pharmaceutical's net margin of -81.79%. Krystal Biotech's return on equity of 19.34% beat Ultragenyx Pharmaceutical's return on equity.

Company Net Margins Return on Equity Return on Assets
Krystal Biotech54.82% 19.34% 17.65%
Ultragenyx Pharmaceutical -81.79%-1,024.42%-44.40%

Krystal Biotech presently has a consensus price target of $365.40, indicating a potential upside of 6.93%. Ultragenyx Pharmaceutical has a consensus price target of $58.89, indicating a potential upside of 128.96%. Given Ultragenyx Pharmaceutical's higher possible upside, analysts clearly believe Ultragenyx Pharmaceutical is more favorable than Krystal Biotech.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Krystal Biotech
0 Sell rating(s)
2 Hold rating(s)
10 Buy rating(s)
1 Strong Buy rating(s)
2.92
Ultragenyx Pharmaceutical
1 Sell rating(s)
2 Hold rating(s)
15 Buy rating(s)
1 Strong Buy rating(s)
2.84

Summary

Krystal Biotech beats Ultragenyx Pharmaceutical on 11 of the 16 factors compared between the two stocks.

How does Ultragenyx Pharmaceutical compare to Nuvalent?

Ultragenyx Pharmaceutical (NASDAQ:RARE) and Nuvalent (NASDAQ:NUVL) are both mid-cap healthcare companies, but which is the better business? We will contrast the two businesses based on the strength of their dividends, analyst recommendations, risk, media sentiment, institutional ownership, earnings, valuation and profitability.

Nuvalent has lower revenue, but higher earnings than Ultragenyx Pharmaceutical. Nuvalent is trading at a lower price-to-earnings ratio than Ultragenyx Pharmaceutical, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Ultragenyx Pharmaceutical$673M3.77-$575M-$5.84N/A
NuvalentN/AN/A-$425.38M-$6.06N/A

In the previous week, Ultragenyx Pharmaceutical had 32 more articles in the media than Nuvalent. MarketBeat recorded 32 mentions for Ultragenyx Pharmaceutical and 0 mentions for Nuvalent. Ultragenyx Pharmaceutical's average media sentiment score of 0.98 beat Nuvalent's score of 0.00 indicating that Ultragenyx Pharmaceutical is being referred to more favorably in the media.

Company Overall Sentiment
Ultragenyx Pharmaceutical Positive
Nuvalent Neutral

Nuvalent has a net margin of 0.00% compared to Ultragenyx Pharmaceutical's net margin of -81.79%. Nuvalent's return on equity of -40.11% beat Ultragenyx Pharmaceutical's return on equity.

Company Net Margins Return on Equity Return on Assets
Ultragenyx Pharmaceutical-81.79% -1,024.42% -44.40%
Nuvalent N/A -40.11%-35.43%

97.7% of Ultragenyx Pharmaceutical shares are held by institutional investors. Comparatively, 97.3% of Nuvalent shares are held by institutional investors. 5.2% of Ultragenyx Pharmaceutical shares are held by insiders. Comparatively, 5.0% of Nuvalent shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Ultragenyx Pharmaceutical has a beta of 0.35, meaning that its stock price is 65% less volatile than the broader market. Comparatively, Nuvalent has a beta of 1.14, meaning that its stock price is 14% more volatile than the broader market.

Ultragenyx Pharmaceutical presently has a consensus target price of $58.89, suggesting a potential upside of 128.96%. Nuvalent has a consensus target price of $127.73, suggesting a potential upside of 3.04%. Given Ultragenyx Pharmaceutical's stronger consensus rating and higher probable upside, equities research analysts clearly believe Ultragenyx Pharmaceutical is more favorable than Nuvalent.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Ultragenyx Pharmaceutical
1 Sell rating(s)
2 Hold rating(s)
15 Buy rating(s)
1 Strong Buy rating(s)
2.84
Nuvalent
1 Sell rating(s)
15 Hold rating(s)
4 Buy rating(s)
0 Strong Buy rating(s)
2.15

Summary

Ultragenyx Pharmaceutical beats Nuvalent on 11 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding RARE and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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RARE vs. The Competition

MetricUltragenyx PharmaceuticalBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$2.55B$4.01B$7.36B$12.81B
Dividend YieldN/A3.64%2.53%10.78%
P/E Ratio-4.406.91211.9120.71
Price / Sales3.771,375.63631.7595.36
Price / CashN/A44.9429.0336.89
Price / Book-30.9917.2611.186.40
Net Income-$575M-$22.72M$3.46B$347.95M
7 Day Performance-1.57%2.89%1.98%0.91%
1 Month Performance-4.39%9.74%7.32%5.10%
1 Year Performance-13.63%54.81%24.76%16.16%

Ultragenyx Pharmaceutical Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
RARE
Ultragenyx Pharmaceutical
3.4211 of 5 stars
$25.72
-0.4%
$58.89
+129.0%
-13.3%$2.55B$673MN/A1,371
ABVX
Abivax
2.6767 of 5 stars
$120.73
+1.5%
$156.50
+29.6%
+48.7%$10.38BN/AN/A61
PRAX
Praxis Precision Medicines
2.9726 of 5 stars
$376.38
+2.6%
$579.55
+54.0%
+670.5%$10.24B$8.55MN/A110
PTGX
Protagonist Therapeutics
1.9926 of 5 stars
$158.62
+2.3%
$140.53
-11.4%
+168.5%$10.04B$281.99M154.00120
KRYS
Krystal Biotech
4.1818 of 5 stars
$335.73
+1.0%
$365.40
+8.8%
+130.3%$9.83B$440.48M42.07210

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This page (NASDAQ:RARE) was last updated on 8/24/2026 by MarketBeat.com Staff.
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