Oncolytics Biotech Inc. is a clinical-stage biotechnology company dedicated to developing pelareorep, an oncolytic immunotherapy derived from a naturally occurring virus designed to target and kill cancer cells while stimulating the body’s immune response. The company’s primary research and development efforts focus on leveraging pelareorep as a platform technology, evaluating its potential both as a standalone treatment and in combination with established cancer therapies, including chemotherapy, targeted agents, and immuno-oncology drugs.
The company’s product pipeline centers on multiple Phase II and exploratory studies across a range of solid tumors. Key investigational indications include breast cancer, head and neck cancer, metastatic pancreatic cancer, and non–small cell lung cancer. By partnering with leading academic institutions and pharmaceutical collaborators, Oncolytics has broad access to patients and trial sites in North America, Europe, and the Asia-Pacific region, facilitating data collection on safety, efficacy, and mechanisms of action.
Founded in 1998 as a spin-out from the University of Calgary, Oncolytics has built a robust intellectual property portfolio and advanced its lead candidate through successive stages of clinical evaluation. The company operates research facilities in Calgary, Alberta, and maintains strategic partnerships to support development and commercialization activities. Its global footprint enables ongoing dialogue with regulators and key opinion leaders to expedite the development pathway for pelareorep.
Oncolytics is led by a seasoned management team with deep expertise in oncology drug development, virology, and regulatory affairs. Under the direction of Chief Executive Officer Lee Schrader, the company continues to expand its clinical trial network and engage with potential collaborators to optimize combination strategies. Oncolytics’ board and scientific advisors include individuals with extensive experience in biotechnology, pharmaceuticals, and academic medicine, positioning the company to advance its novel immunotherapeutic approach toward potential market approval.
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