Opthea (OPT) Institutional Ownership $3.41 +0.23 (+7.23%) As of 08/29/2025 Add Compare Share Share Ownership Stock AnalysisAnalyst ForecastsChartCompetitorsFDA EventsFinancialsHeadlinesOwnershipSEC FilingsShort InterestTrendsBuy This Stock Institutional Ownership Changes (13F Filings) for Opthea (NASDAQ:OPT)CurrentInstitutional OwnershipPercentage55.95%Number ofInstitutional Buyers(last 12 months)8TotalInstitutional Inflows(last 12 months)$8.81MNumber ofInstitutional Sellers(last 12 months)3TotalInstitutional Outflows(last 12 months)$443.74K Get OPT Insider Trade Alerts Want to know when executives and insiders are buying or selling Opthea stock? Sign up for InsiderTrades.com's daily newsletter to get the latest insider transactions delivered to your inbox daily. 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Skip Chart & View Institutional Buying and Selling Data OPT Institutional Buying and Selling by Quarter Opthea Major Shareholders & Ownership History Export to ExcelReporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails5/23/2025 Twin Lakes Capital Management LLC33,156$113K0.1%+67.4%0.022% 5/15/2025 EP Wealth Advisors LLC10,000$34K0.0%N/A0.006% 5/15/2025 Baker BROS. Advisors LP2,087,320$7.12M0.1%-4.0%1.356% 5/15/2025 OLD Mission Capital LLC19,167$65K0.0%+78.7%0.012% 5/14/2025 Hsbc Holdings PLC105,939$356K0.0%-25.7%0.069% 5/13/2025 Regal Partners Ltd5,193,688$17.71M1.8%+78.6%3.374% 2/17/2025 Millennium Management LLC61,101$241K0.0%-9.3%0.045% 2/17/2025 Citadel Advisors LLC19,998$79K0.0%N/A0.015% 2/14/2025 Hsbc Holdings PLC142,515$556K0.0%N/A0.104% 2/12/2025 OLD Mission Capital LLC10,728$42K0.0%N/A0.008% Get the Latest News and Ratings for OPT and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Opthea and its competitors with MarketBeat's FREE daily newsletter. 1/30/2025 ABC Arbitrage SA10,216$40K0.0%N/A0.007% 11/18/2024 Twin Lakes Capital Management LLC19,806$81K0.0%N/A0.034% 11/15/2024 Jane Street Group LLC26,632$114K0.0%N/A0.046% 8/5/2024 Victory Capital Management Inc.840,040$1.61M0.0%-1.8%1.439% 5/15/2024 Baker BROS. Advisors LP2,177,826$8.95M0.1%-15.9%3.729% 11/15/2023 Regal Partners Ltd2,895,987$5.05M1.1%-0.6%4.959% 11/6/2023 Victory Capital Management Inc.884,335$1.50M0.0%-8.0%1.514% 7/27/2023 Victory Capital Management Inc.961,485$2.69M0.0%-14.7%1.646% 5/2/2023 Victory Capital Management Inc.1,127,566$4.47M0.0%-4.3%1.931% 3/10/2023 Victory Capital Management Inc.1,177,995$6.60M0.0%-28.3%2.017% 2/9/2023 Victory Capital Management Inc.1,177,995$6.60M0.0%-28.3%2.018% 11/2/2022 Victory Capital Management Inc.1,643,585$10.17M0.0%+2.5%2.829% 9/9/2022 Regal Partners Ltd2,883,790$18.17M3.1%N/A5.697% 8/15/2022 Laurion Capital Management LP22,660$143K0.0%-9.4%0.051% 8/1/2022 Victory Capital Management Inc.1,604,227$10.11M0.0%+0.5%3.644% 5/4/2022 Victory Capital Management Inc.1,596,207$9.82M0.0%+1.4%3.629% 2/7/2022 Victory Capital Management Inc.1,574,694$11.81M0.0%+6.7%3.580% 11/2/2021 Victory Capital Management Inc.1,475,893$11.82M0.0%+3.0%3.364% 8/17/2021 Millennium Management LLC194,334$1.54M0.0%-6.0%0.443% 8/3/2021 Victory Capital Management Inc.1,433,254$11.38M0.0%+1.8%3.266% (Data available from 1/1/2016 forward) OPT Institutional Ownership - Frequently Asked Questions Who are the largest shareholders of OPT shares? During the previous two years, 11 institutional investors and hedge funds held shares of Opthea. The most heavily invested institutionals were Regal Partners Ltd ($17.71M), Baker BROS. Advisors LP ($7.12M), Victory Capital Management Inc. ($1.61M), Hsbc Holdings PLC ($356K), Millennium Management LLC ($241K), Jane Street Group LLC ($114K), and Twin Lakes Capital Management LLC ($113K).Learn more on Opthea's institutional investors. What percentage of Opthea's stock is owned by institutional investors? 55.95% of Opthea's stock is owned by institutional investors. Learn more on OPT's institutional investor holdings. Which institutional investors have been buying Opthea's stock? The following institutional investors have purchased Opthea's stock in the last 24 months: Regal Partners Ltd ($2.29M), Hsbc Holdings PLC ($142.52K), Twin Lakes Capital Management LLC ($33.16K), Jane Street Group LLC ($26.63K), Citadel Advisors LLC ($20.00K), OLD Mission Capital LLC ($19.17K), and ABC Arbitrage SA ($10.22K). How much institutional buying is happening at Opthea? Institutional investors have bought a total of 2,547,969 shares in the last 24 months. This purchase volume represents approximately $8.81M in transactions. Which of Opthea's major shareholders have been selling company stock? The following institutional investors have sold Opthea stock in the last 24 months: Baker BROS. Advisors LP ($86.30K), Hsbc Holdings PLC ($36.58K), and Millennium Management LLC ($6.29K). How much institutional selling is happening at Opthea? Institutional investors have sold a total of 129,169 shares in the last 24 months. This volume of shares sold represents approximately $443.74K in transactions. Related Companies IRON Major Shareholders CGON Major Shareholders BLTE Major Shareholders MESO Major Shareholders ADPT Major Shareholders SRPT Major Shareholders ANIP Major Shareholders ARQT Major Shareholders VCEL Major Shareholders DYN Major Shareholders This page (NASDAQ:OPT) was last updated on 9/2/2025 by MarketBeat.com Staff From Our PartnersMan Who Called Nvidia at $1.10 Says Buy This Now...In 2004, one man called Nvidia before just about anyone knew it existed. 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