Pulse Biosciences, Inc. is a medical technology company focused on the development and commercialization of novel bioelectric therapies using its proprietary Nano-Pulse Stimulation (NPS) platform. The company’s technology delivers ultra-short electrical pulses that create transient nanopores in cell membranes, triggering programmed cell death without the use of heat or chemical agents. This non‐thermal approach aims to provide precise tissue ablation with minimal collateral damage, making it applicable across a range of dermatological and oncological indications.
The company’s primary commercial product, the CellFX® System, is designed to treat benign skin lesions and select aesthetic dermatology applications. CellFX has received regulatory approvals in multiple regions for the clearance of non‐cancerous dermatologic conditions, and clinical studies are ongoing to expand its use in early-stage skin cancers. In parallel, Pulse Biosciences is advancing its oncology pipeline, known as PulseTx®, which leverages NPS technology to target internal tumors and potentially enhance the body’s immune response against cancer cells.
Founded in 2013 and headquartered in Hayward, California, Pulse Biosciences has established a commercial presence in North America and is pursuing regulatory clearances in Europe and Asia-Pacific markets. The company collaborates with leading academic institutions and research centers to validate new clinical applications for its NPS platform. Strategic partnerships and investigator-initiated trials are central to its efforts to broaden the technology’s reach into both aesthetic and therapeutic segments.
Under the leadership of CEO Vadim Gliner, Pulse Biosciences emphasizes innovation and science-driven commercialization. The executive team comprises veterans in medical device development and life sciences, supporting the company’s goal of bringing minimally invasive bioelectric therapies from the laboratory to clinical practice. Pulse Biosciences continues to invest in research and development, aiming to expand its product portfolio and address unmet medical needs in dermatology and oncology.
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