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Relay Therapeutics (RLAY) Short Interest Ratio & Short Volume

Relay Therapeutics logo
$17.47 0.00 (0.00%)
Closing price 09/25/2026 04:00 PM Eastern
Extended Trading
$17.62 +0.15 (+0.85%)
As of 09/25/2026 07:58 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.
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Relay Therapeutics Short Interest Overview

As of September 15, 2026, Relay Therapeutics (RLAY) had a short interest of 44.49 million shares sold short, representing 21.38% of the public float. This marks a 2.15% increase in short interest since the prior report. The short interest ratio (days to cover) is 14.2, meaning it would take 14.2 days of the average trading volume of 3.45 million shares to cover all short positions.

Current Short Interest
44,487,428 shares
Previous Short Interest
43,550,416 shares
Change Vs. Previous Month
2.15%
Dollar Volume Sold Short
$843.93 million
Short Interest Ratio
14.2 Days to Cover
Last Record Date
September 15, 2026
Outstanding Shares
219,140,000 shares
Short Percent of Float
21.38%
Today's Trading Volume
2,983,616 shares
Average Trading Volume
3,449,030 shares
Today's Volume Vs. Average
87%
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Short Interest ChartDays to Cover ChartShort Percent of Float Chart

RLAY Short Interest Over Time

RLAY Days to Cover Over Time

RLAY Percentage of Float Shorted Over Time

Relay Therapeutics Tesla Short Interest History & Recent Changes

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Report DateTotal Shares Sold ShortDollar Volume Sold ShortChange from Previous ReportPercentage of Float ShortedDays to CoverPrice on Report Date
9/15/202644,487,428 shares $843.93 million +2.2%21.4%14.22 $18.97
8/31/202643,550,416 shares $800.46 million +5.3%20.9%16.73 $18.38
8/14/202641,359,202 shares $821.39 million +2.8%19.9%21.59 $19.86
7/31/202640,250,044 shares $757.91 million -5.4%19.3%17.41 $18.83
7/15/202642,557,689 shares $830.30 million -1.1%23.4%13.38 $19.51
6/30/202643,041,464 shares $805.31 million +12.9%23.7%7.24 $18.71
6/15/202638,123,615 shares $570.33 million +10.9%21.0%9.85 $14.96
5/29/202634,389,240 shares $483.17 million +19.3%18.9%5.74 $14.05
5/15/202628,824,051 shares $351.65 million +5.2%15.8%10.29 $12.20
4/30/202627,410,626 shares $355.24 million +1.5%15.1%8.72 $12.96
4/15/202626,998,295 shares $418.20 million +23.1%14.8%6.15 $15.49
3/31/202621,938,652 shares $218.29 million +10.6%12.1%10.25 $9.95
3/13/202619,845,792 shares $205.60 million +2.1%11.6%6.43 $10.36
2/27/202619,437,056 shares $199.42 million -2.3%11.4%9.78 $10.26
2/13/202619,890,452 shares $177.62 million -17.2%10.9%7.34 $8.93
1/30/202624,025,317 shares $184.03 million +7.4%14.5%9.52 $7.66
1/15/202622,381,326 shares $170.77 million +0.7%13.5%12.07 $7.63
12/31/202522,232,137 shares $188.08 million +9.5%13.4%9.53 $8.46
12/15/202520,296,216 shares $172.11 million -12.4%12.2%10.19 $8.48
11/28/202523,160,072 shares $181.92 million +8.4%14.0%10.93 $7.86
11/14/202521,371,170 shares $134.42 million +19.6%12.9%8.31 $6.29
10/31/202517,870,256 shares $127.59 million -18.5%10.8%8.42 $7.14
10/15/202521,930,000 shares $144.96 million -3.1%13.3%12.4 $6.61
9/30/202522,640,000 shares $118.18 million +0.6%N/A11.6 $5.22
9/15/202522,500,000 shares $91.35 million -1.0%N/A11.9 $4.06
8/31/202522,730,000 shares $81.60 million 0.0%13.9%11.9 $3.59
8/15/202522,740,000 shares $80.50 million +1.6%N/A11.8 $3.54
7/31/202522,380,000 shares $78.78 million +4.0%13.6%11 $3.52
7/15/202521,520,000 shares $75.32 million No ChangeN/A10.4 $3.50
6/30/202521,520,000 shares $74.46 million -4.4%13.2%10.4 $3.46
6/15/202522,520,000 shares $72.51 million -0.6%13.8%9.9 $3.22
5/31/202522,650,000 shares $68.18 million -2.2%14.1%9.4 $3.01
5/15/202523,160,000 shares $64.62 million +19.0%14.5%9 $2.79
4/30/202519,470,000 shares $64.84 million +6.1%N/A7.7 $3.33
4/15/202518,360,000 shares $50.67 million +1.7%11.5%8 $2.76
3/31/202518,060,000 shares $47.32 million -5.5%11.3%7.1 $2.62
3/15/202519,120,000 shares $69.98 million +18.1%11.9%8.2 $3.66
2/28/202516,190,000 shares $55.21 million +2.5%10.1%6.8 $3.41
2/15/202515,790,000 shares $63.16 million +0.8%9.9%6.8 $4.00
1/31/202515,660,000 shares $70.00 million +3.0%N/A6.8 $4.47
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1/15/202515,210,000 shares $57.95 million +1.7%N/A6.6 $3.81
12/31/202414,950,000 shares $61.59 million +23.8%N/A7.2 $4.12
12/15/202412,080,000 shares $56.90 million +1.3%N/A6.2 $4.71
11/30/202411,930,000 shares $56.07 million +2.8%N/A5.7 $4.70
11/15/202411,610,000 shares $59.27 million -3.6%N/A5.4 $5.11
10/31/202412,040,000 shares $67.85 million +1.5%N/A6.1 $5.64
10/15/202411,860,000 shares $79.94 million -4.1%N/A6.2 $6.74
9/30/202412,370,000 shares $87.58 million +24.7%N/A6.5 $7.08
9/15/20249,920,000 shares $75.39 million +9.4%N/A5.4 $7.60
8/31/20249,070,000 shares $61.59 million +0.2%N/A5.2 $6.79
8/15/20249,050,000 shares $60.36 million +2.6%N/A7.4 $6.67
7/31/20248,820,000 shares $72.50 million +4.6%N/A6.5 $8.22
7/15/20248,430,000 shares $69.72 million +4.7%N/A6.2 $8.27
6/30/20248,050,000 shares $52.49 million -18.3%N/A6.1 $6.52
6/15/20249,850,000 shares $72.00 million +2.6%N/A7.5 $7.31
5/31/20249,600,000 shares $61.54 million -19.3%N/A7.3 $6.41
5/15/202411,890,000 shares $80.79 million +3.1%N/A9.5 $6.80
4/30/202411,530,000 shares $75.18 million +7.9%N/A9.4 $6.52
4/15/202410,690,000 shares $73.01 million -4.3%N/A9 $6.83
3/31/202411,170,000 shares $92.71 million -5.4%N/A10 $8.30
3/15/202411,810,000 shares $93.89 million +7.4%N/A10.9 $7.95
2/29/202411,000,000 shares $110.22 million +12.1%N/A10.5 $10.02
2/15/20249,810,000 shares $104.67 million +3.8%N/A9.2 $10.67
1/31/20249,450,000 shares $87.41 million -16.3%11.0%9.5 $9.25
1/15/202411,290,000 shares $124.19 million -6.0%13.1%10.3 $11.00
12/31/202312,010,000 shares $132.23 million -12.3%14.1%10.4 $11.01
12/15/202313,700,000 shares $138.92 million -6.4%16.1%11.5 $10.14
11/30/202314,630,000 shares $115.72 million -0.1%17.3%12.1 $7.91
11/15/202314,640,000 shares $125.17 million +1.5%17.3%12.7 $8.55
10/31/202314,430,000 shares $95.24 million +4.8%16.9%12.9 $6.60
10/15/202313,770,000 shares $106.58 million -29.0%16.3%13.5 $7.74
9/30/202319,400,000 shares $163.15 million -3.4%22.9%19.9 $8.41
9/15/202320,080,000 shares $188.15 million +1.0%23.7%21 $9.37
8/31/202319,890,000 shares $203.28 million -3.9%23.5%19.1 $10.22
8/15/202320,700,000 shares $219.83 million +5.5%24.5%18.3 $10.62
7/31/202319,630,000 shares $247.34 million -1.1%23.3%16.4 $12.60
7/15/202319,840,000 shares $242.64 million -3.1%23.8%14.7 $12.23
6/30/202320,480,000 shares $257.23 million -2.9%24.6%12.1 $12.56
6/15/202321,080,000 shares $269.61 million -0.4%25.3%12.3 $12.79
5/31/202321,160,000 shares $235.72 million -1.5%25.4%13.1 $11.14
5/15/202321,480,000 shares $221.03 million +8.5%25.8%13.6 $10.29
4/30/202319,800,000 shares $225.13 million +1.4%23.4%13 $11.37
4/15/202319,530,000 shares $340.60 million +3.3%23.1%13.3 $17.44
3/31/202318,910,000 shares $311.45 million +5.5%22.4%15.4 $16.47
3/15/202317,930,000 shares $295.85 million +0.8%21.3%13.8 $16.50
2/28/202317,780,000 shares $287.15 million +3.0%21.1%13 $16.15
2/15/202317,270,000 shares $317.25 million -0.6%20.6%12.9 $18.37
1/31/202317,380,000 shares $372.97 million -6.9%20.7%13 $21.46
1/15/202318,660,000 shares $387.57 million +10.5%22.2%14.7 $20.77
12/30/202216,890,000 shares $252.34 million +25.8%20.0%13.8 $14.94
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12/15/202213,430,000 shares $230.59 million +7.5%15.9%12.2 $17.17
11/30/202212,490,000 shares $232.06 million -4.3%14.8%11.1 $18.58
11/15/202213,050,000 shares $258.39 million -3.1%15.4%10.5 $19.80
10/31/202213,460,000 shares $299.08 million +3.1%16.5%10.9 $22.22
10/15/202213,060,000 shares $254.80 million +7.2%16.1%10.4 $19.51
9/30/202212,180,000 shares $272.47 million +4.0%15.0%10.2 $22.37
9/15/202211,710,000 shares $293.69 million -25.0%15.9%9.2 $25.08
8/31/202215,620,000 shares $358.79 million -15.2%21.2%13.4 $22.97
8/15/202218,420,000 shares $386.27 million -1.8%25.1%18.1 $20.97
7/31/202218,760,000 shares $356.82 million -1.4%25.6%17.4 $19.02
7/15/202219,020,000 shares $368.99 million -6.8%26.0%17.9 $19.40
6/30/202220,410,000 shares $341.87 million +11.2%27.9%20.2 $16.75
6/15/202218,360,000 shares $263.10 million +2.5%25.1%19.2 $14.33
5/31/202217,920,000 shares $291.74 million +9.6%24.5%23.3 $16.28
5/15/202216,350,000 shares $287.43 million +11.7%22.3%21.9 $17.58
4/30/202214,640,000 shares $348.87 million +2.0%19.9%22.2 $23.83
4/15/202214,360,000 shares $441.43 million -1.8%19.6%22.8 $30.74
3/31/202214,620,000 shares $437.58 million -8.9%19.9%22.6 $29.93
3/15/202216,050,000 shares $367.87 million +4.4%21.9%26.4 $22.92
2/28/202215,380,000 shares $370.81 million +2.1%21.0%26.1 $24.11
2/15/202215,070,000 shares $323.25 million +1.3%21.6%25.1 $21.45
1/31/202214,880,000 shares $329.29 million +7.5%21.1%26.3 $22.13
1/15/202213,840,000 shares $363.85 million +1.1%22.2%25.8 $26.29
12/31/202113,690,000 shares $420.42 million -3.9%21.9%19 $30.71
12/15/202114,250,000 shares $414.11 million +3.3%22.8%17.7 $29.06
11/30/202113,790,000 shares $405.70 million +2.6%22.3%16.5 $29.42
11/15/202113,440,000 shares $474.70 million +6.6%21.8%15.8 $35.32
10/29/202112,610,000 shares $419.28 million -1.3%22.5%14.5 $33.25
10/15/202112,770,000 shares $435.58 million +21.0%22.8%15.3 $34.11
9/30/202110,550,000 shares $332.64 million +5.5%18.8%16.8 $31.53

RLAY Short Interest - Frequently Asked Questions

Short interest is the volume of Relay Therapeutics shares that have been sold short but have not yet been closed out or covered. As of September 15th, traders have sold 44,487,428 shares of RLAY short. 21.38% of Relay Therapeutics' shares are currently sold short. Learn More on Relay Therapeutics' current short interest.

The short interest ratio, also known as the "days to cover ratio", is calculated by dividing the number of shares of a stock sold short divided by its average trading volume. A short interest ratio ranging between 1 and 4 generally indicates strong positive sentiment about a stock and a lack of short sellers. A short interest ratio of 10 or greater indicates strong pessimism about a stock. RLAY shares currently have a short interest ratio of 14.2. Learn More on Relay Therapeutics's short interest ratio.

Companies that have a short interest as a percentage of float below 10% indicates positive investor sentiment and few short sellers. Stocks with a short interest percentage above 10% is considered high, suggesting some investors are pessimistic about the stock. Companies with a short interest percentage of 20% or more indicates widespread negative sentiment. 21.38% of Relay Therapeutics' floating shares are currently sold short.

Relay Therapeutics saw a increase in short interest in September. As of September 15th, there was short interest totaling 44,487,428 shares, an increase of 2.2% from the previous total of 43,550,416 shares. Changes in short volume can be used to identify positive and negative investor sentiment. Investors that short sell a stock are betting that its price will decline in the future. An increase in short sale volume suggests bearish (negative) sentiment among investors. A decrease on short sale volume suggests bullish (positive) sentiment.

21.38% of Relay Therapeutics' shares are currently sold short. Here is how the short interest of companies in the industry of "biotechnology" compare to Relay Therapeutics: Ascendis Pharma A/S (10.59%), Exelixis, Inc. (10.94%), Summit Therapeutics PLC (31.21%), BridgeBio Pharma, Inc. (12.85%), Halozyme Therapeutics, Inc. (13.69%), BioMarin Pharmaceutical Inc. (5.24%), Madrigal Pharmaceuticals, Inc. (11.84%), Krystal Biotech, Inc. (12.30%), Kymera Therapeutics, Inc. (15.07%), Arrowhead Pharmaceuticals, Inc. (6.83%),

As of the most recent reporting period, the following stocks had the largest short interest positions: SPDR S&P 500 ETF Trust ($75.21 billion), Invesco QQQ ($46.31 billion), iShares Russell 2000 ETF ($27.98 billion), SPDR S&P Biotech ETF ($11.59 billion), Nebius Group N.V. ($9.70 billion), Canadian Natural Resources Limited ($9.42 billion), iShares 20+ Year Treasury Bond ETF ($8.70 billion), iShares iBoxx $ High Yield Corporate Bond ETF ($8.53 billion), iShares iBoxx $ Investment Grade Corporate Bond ETF ($7.79 billion), and Financial Select Sector SPDR Fund ($7.74 billion). View all of the most shorted stocks.

Short selling RLAY is an investing strategy that aims to generate trading profit from Relay Therapeutics as its price is falling. RLAY shares are trading down $0.26 today. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit.

A short squeeze for Relay Therapeutics occurs when it has a large amount of short interest and its stock increases in price. This forces short sellers to cover their short interest positions by buying actual shares of RLAY, which in turn drives the price of the stock up even further.

Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including RLAY, twice per month. The most recent reporting period available is September, 15 2026.

Understanding short interest metrics can help you assess how traders are positioning around a stock like RLAY:

  • Shares Sold Short: The total number of shares that have been sold by short sellers but have not yet been covered or closed out. A high number may indicate bearish sentiment.
  • Short Float: The percentage of a company’s publicly available shares (or "float") that are sold short. A higher short float suggests a greater portion of the stock is being bet against.
  • Days to Cover (Short Interest Ratio): This estimates how many days it would take short sellers to cover their positions, based on average daily trading volume. Higher values can signal potential for a short squeeze if buying pressure increases.

These metrics are often used by traders to gauge sentiment, volatility risk, and the potential for price movements based on short covering activity.


Related Companies
Short Interest Tools

Short interest data for NASDAQ:RLAY is sourced from the Financial Industry Regulatory Authority (FINRA), with the most recent report published on 9/24/2026. FINRA publishes updated short interest twice a month.
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