NASDAQ:SHPH Shuttle Pharmaceuticals (SHPH) Stock Price, News & Analysis $4.60 +0.95 (+26.03%) Closing price 08/5/2026 04:00 PM EasternExtended Trading$4.49 -0.11 (-2.37%) As of 08/5/2026 08:00 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOwnershipSEC FilingsTrendsBuy This Stock About Shuttle Pharmaceuticals Stock (NASDAQ:SHPH) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get SHPH alerts:Sign Up Key Stats Today's Range$3.84▼$4.6050-Day Range$2.78▼$5.3852-Week Range$2.58▼$55.90Volume1.57 million shsAverage Volume4.30 million shsMarket Capitalization$2.94 millionP/E RatioN/ADividend YieldN/APrice TargetN/AConsensus RatingSell Company Overview Shuttle Pharmaceuticals Holdings, Inc., a clinical stage pharmaceutical company, develops novel therapies to cure cancers. It develops Ropidoxuridine, an oral halogenated pyrimidine to treat patients with brain tumors and sarcomas SP-1-161, an HDAC inhibitor that initiates the mutated in ataxia-telangiectasia response pathway for radiation sensitizing cancer cells and protecting normal cells; SP-2-225, a pre-clinical class IIb that effects on the regulation of the immune system; and SP-1-303, a pre-clinical selective Class I HDAC for the treatment of ER positive cancers . The company is based in Gaithersburg, Maryland. Read More Shuttle Pharmaceuticals Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks15th Percentile Overall ScoreSHPH MarketRank™: Shuttle Pharmaceuticals scored higher than 15% of companies evaluated by MarketBeat. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion0.7 / 5Analyst RatingSell Consensus RatingShuttle Pharmaceuticals has received a consensus rating of Sell. The company's average rating score is 1.00, and is based on no strong buy ratings, no buy ratings, no hold ratings, and 1 sell rating.Amount of Analyst CoverageShuttle Pharmaceuticals has only been the subject of 1 research reports in the past 90 days.Read more about Shuttle Pharmaceuticals' stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthN/A Price to Earnings Ratio vs. the MarketThe P/E ratio of Shuttle Pharmaceuticals is -0.10, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Shuttle Pharmaceuticals is -0.10, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioShuttle Pharmaceuticals has a P/B Ratio of 0.41. P/B Ratios below 1 indicate that a company could be undervalued with respect to its assets and liabilities. Short Interest2.0 / 5Short Interest LevelBearish Percentage of Shares Shorted77.14% of the float of Shuttle Pharmaceuticals has been sold short.Short Interest Ratio / Days to CoverShuttle Pharmaceuticals has a short interest ratio ("days to cover") of 0.06, which is generally considered an acceptable ratio of short interest to trading volume.Change versus previous monthShort interest in Shuttle Pharmaceuticals has recently increased by 213.00%, indicating that investor sentiment is decreasing significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldShuttle Pharmaceuticals does not currently pay a dividend.Dividend GrowthShuttle Pharmaceuticals does not have a long track record of dividend growth. News and Social Media1.3 / 5News SentimentN/A Search Interest1 people have searched for SHPH on MarketBeat in the last 30 days. MarketBeat Follows2 people have added Shuttle Pharmaceuticals to their MarketBeat watchlist in the last 30 days. Company Ownership3.0 / 5Insider TradingAcquiring Shares Net Insider BuyingOver the last three months, insiders have purchased a net $49,636.00 in company stock, which represents 1.6860% of the company's market cap.Insider Buying vs. Insider SellingIn the past three months, Shuttle Pharmaceuticals insiders have bought 37.57% more of their company's stock than they have sold. Specifically, they have bought $181,764.00 in company stock and sold $132,128.00 in company stock.Percentage Held by Insiders1.31% of the stock of Shuttle Pharmaceuticals is held by insiders.Percentage Held by Institutions4.58% of the stock of Shuttle Pharmaceuticals is held by institutions.Read more about Shuttle Pharmaceuticals' insider trading history. Receive SHPH Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Shuttle Pharmaceuticals and its competitors with MarketBeat's FREE daily newsletter. 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(NASDAQ:SHPH) Short Interest UpdateJuly 27, 2026 | americanbankingnews.comShuttle Pharmaceuticals (NASDAQ:SHPH) Major Shareholder Buys 8,266 SharesJuly 14, 2026 | insidertrades.comHere’s the stock symbol I’ve promisedWhitney Tilson of Stansberry Research has long recommended Berkshire Hathaway as a core retirement holding - but now he believes he's found something better. This under-the-radar company sits at the intersection of America's two most important industries, including AI, pays massive dividends, and attracted a famous money manager who put 60% of his multi-billion-dollar fund into it. Tilson is revealing the name and ticker symbol completely free - no credit card or email required. | Stansberry Research (Ad)Shuttle Pharmaceuticals (NASDAQ:SHPH) Major Shareholder Financial Lp Hrt Sells 10,580 Shares of StockJuly 10, 2026 | insidertrades.comShuttle Pharmaceuticals (NASDAQ:SHPH) Major Shareholder Acquires 7,851 Shares of StockJuly 8, 2026 | insidertrades.comSHPH Share News TodayJune 26, 2026 | uk.investing.comShuttle Pharma's United Dogecoin eyes multiple revenue streams with AI data centersJune 26, 2026 | msn.comShuttle Pharmaceuticals Announces Planned Reverse Stock SplitJune 11, 2026 | tipranks.comSee More Headlines SHPH Stock Analysis - Frequently Asked Questions How have SHPH shares performed this year? Shuttle Pharmaceuticals' stock was trading at $18.00 on January 1st, 2026. Since then, SHPH stock has decreased by 74.4% and is now trading at $4.60. How were Shuttle Pharmaceuticals' earnings last quarter? Shuttle Pharmaceuticals Holdings, Inc. (NASDAQ:SHPH) posted its quarterly earnings data on Thursday, May, 8th. The company reported ($75.00) earnings per share for the quarter. When did Shuttle Pharmaceuticals' stock split? Shuttle Pharmaceuticals's stock reverse split on the morning of Thursday, June 11th 2026.The 1-10 reverse split was announced on Tuesday, June 9th 2026. The number of shares owned by shareholders was adjusted after the market closes on Wednesday, June 10th 2026. An investor that had 100 shares of stock prior to the reverse split would have 10 shares after the split. When did Shuttle Pharmaceuticals IPO? Shuttle Pharmaceuticals (SHPH) raised $10 million in an initial public offering (IPO) on Tuesday, August 30th 2022. The company issued 1,225,888 shares at $8.13 per share. How do I buy shares of Shuttle Pharmaceuticals? Shares of SHPH stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Shuttle Pharmaceuticals own? Based on aggregate information from My MarketBeat watchlists, some other companies that Shuttle Pharmaceuticals investors own include MSP Recovery (LIFW), NIO (NIO), Tesla (TSLA), Broadcom (AVGO), AMTD Digital (HKD) and NVIDIA (NVDA). Company Calendar Last Earnings5/08/2025Today8/06/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Yellow Zone (2m+) 1-Year History Aug 25 Nov 25 Feb 26 May 26 Aug 26 SHPH's financial health is in the Yellow zone, according to TradeSmith. SHPH has been in this zone for over 2 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorTechnology Industry Software Sub-IndustryApplication Software Current SymbolNASDAQ:SHPH CIK1757499 Webwww.shuttlepharma.com Phone240-403-4212FaxN/AEmployees5Year Founded2012Profitability EPS (Trailing Twelve Months)($47.70) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$11.72 million Net MarginsN/A Pretax MarginN/A Return on Equity-408.34% Return on Assets-138.15% Debt Debt-to-Equity RatioN/A Current Ratio0.30 Quick Ratio0.30 Sales & Book Value Annual SalesN/A Price / SalesN/A Cash FlowN/A Price / Cash FlowN/A Book Value$11.14 per share Price / Book0.41Miscellaneous Outstanding Shares640,000Free Float629,000Market Cap$2.94 million OptionableNot Optionable Beta0.21 Social Links 7 Best Space Stocks to Own in 2026The space race is growing fast, and you don’t have to have gotten in early on SpaceX to profit. 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