NASDAQ:SION Sionna Therapeutics (SION) Stock Price, News & Analysis $17.44 +0.70 (+4.18%) As of 04:00 PM Eastern Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOwnershipSEC FilingsTrendsBuy This Stock About Sionna Therapeutics Stock (NASDAQ:SION) 30 days 90 days 365 days Advanced Chart View Price History Chart DataSkip Price History Chart Get Sionna Therapeutics alerts:Sign Up Key Stats Today's Range$16.46▼$17.4550-Day Range$12.00▼$21.5752-Week Range$7.26▼$25.19Volume102,397 shsAverage Volume276,979 shsMarket Capitalization$769.45 millionP/E RatioN/ADividend YieldN/APrice Target$38.50Consensus RatingBuy Company Overview Sionna Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing precision medicines for inflammatory and vascular diseases. The company leverages a proprietary targeted protein degradation platform designed to selectively eliminate disease-driving proteins in the endothelium. By engineering modular molecules that bind and shuttle pathological targets to the cellular degradation machinery, Sionna seeks to address mechanisms underlying conditions such as pulmonary arterial hypertension and diabetic nephropathy. The company’s pipeline comprises several preclinical and early-stage clinical programs aimed at modulating key inflammatory pathways and restoring vascular homeostasis. Lead candidates are designed to penetrate tissue barriers and induce sustained clearance of overactive proteins, offering a differentiated approach versus traditional small-molecule inhibitors or biologics. Sionna maintains active research collaborations with academic institutions and contract research organizations to optimize its delivery technologies and expand its therapeutic reach. Founded in 2020, Sionna Therapeutics is headquartered in Cambridge, Massachusetts, with additional research operations in North America and Europe. The executive team brings together experienced professionals from the biopharmaceutical industry, combining expertise in protein engineering, drug development and clinical operations. Sionna’s leadership has emphasized rapid advancement of its most promising candidates through clinical proof-of-concept studies while continuing to broaden its platform capabilities for future indications.AI Generated. May Contain Errors. Read More Receive SION Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Sionna Therapeutics and its competitors with MarketBeat's FREE daily newsletter. Email Address SION Stock News HeadlinesTpg Gp A, Llc Acquires 60,000 Shares of Sionna Therapeutics, Inc. (NASDAQ:SION) StockJuly 2, 2025 | insidertrades.comSION - Sionna Therapeutics Inc News - MorningstarJuly 2, 2025 | morningstar.comMTrump’s Exec Order #14154 could be a “Millionaire-Maker”Former Presidential Advisor, Jim Rickards, says Trump could “rewire our economy and hand millions of Americans a chance at true financial independence in the months ahead.” We recently sat down with Rickards to capture all the key details on tape. July 21 at 2:00 AM | Paradigm Press (Ad)Sionna Therapeutics reports annual meeting resultsJune 15, 2025 | investing.comStifel analysts reiterate buy rating on Sionna Therapeutics stockJune 6, 2025 | uk.investing.comSionna Therapeutics Announces Positive Phase 1 Results For SION-719, SION-451 In Cystic FibrosisJune 6, 2025 | nasdaq.comSionna Therapeutics Shares Rise on Positive Data for its Cystic Fibrosis TreatmentJune 6, 2025 | marketwatch.comSionna Therapeutics Announces Presentation of Preclinical Data that Demonstrate Proprietary Dual Combination Therapies Enable Full CFTR Correction in CFHBE ModelJune 6, 2025 | globenewswire.comSee More Headlines SION Stock Analysis - Frequently Asked Questions How have SION shares performed this year? Sionna Therapeutics' stock was trading at $20.10 on January 1st, 2025. Since then, SION stock has decreased by 13.2% and is now trading at $17.44. How were Sionna Therapeutics' earnings last quarter? Sionna Therapeutics, Inc. (NASDAQ:SION) posted its quarterly earnings results on Monday, May, 12th. The company reported ($0.62) earnings per share (EPS) for the quarter, missing the consensus estimate of ($0.45) by $0.17. When did Sionna Therapeutics IPO? Sionna Therapeutics (SION) raised $191 million in an initial public offering (IPO) on Friday, February 7th 2025. The company issued 10,588,233 shares at a price of $18.00 per share. When does the company's lock-up period expire? Sionna Therapeutics's lock-up period expires on Wednesday, August 6th. Sionna Therapeutics had issued 10,588,233 shares in its public offering on February 7th. The total size of the offering was $190,588,194 based on an initial share price of $18.00. After the end of the company's lock-up period, restrictions preventing major shareholders and company insiders from selling shares in the company will be lifted. How do I buy shares of Sionna Therapeutics? Shares of SION stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. Company Calendar Last Earnings5/12/2025Today7/21/2025Fiscal Year End12/31/2025Get Stock AlertsIndustry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry MED - BIOMED/GENE Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:SION Previous SymbolNASDAQ:SION CIK2036042 WebN/A Phone(617) 819-2020FaxN/AEmployees35Year FoundedN/APrice Target and Rating Average Price Target for Sionna Therapeutics$38.50 High Price Target$45.00 Low Price Target$32.00 Potential Upside/Downside+120.8%Consensus RatingBuy Rating Score (0-4)3.00 Research Coverage3 Analysts Profitability EPS (Trailing Twelve Months)N/A Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet IncomeN/A Net MarginsN/A Pretax MarginN/A Return on EquityN/A Return on AssetsN/A Debt Debt-to-Equity RatioN/A Current Ratio28.73 Quick Ratio28.73 Sales & Book Value Annual SalesN/A Price / SalesN/A Cash FlowN/A Price / Cash FlowN/A Book ValueN/A Price / BookN/AMiscellaneous Outstanding Shares44,120,000Free Float42,403,000Market Cap$769.45 million OptionableN/A BetaN/A Investing Strategies To Help Grow Your Retirement IncomeNeed to stretch out your 401K or Roth IRA plan? 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