Stoke Therapeutics (STOK) News Today $29.90 -0.60 (-1.97%) Closing price 04:00 PM EasternExtended Trading$29.96 +0.06 (+0.20%) As of 07:38 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Headlines Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock Why Is Stoke Therapeutics Down Today?Toggle Visibility of Why Is Stoke Therapeutics Down Today?Stoke Therapeutics, Inc. (NASDAQ:STOK) saw mixed signals today as analysts adjusted earnings forecasts, insiders sold shares and trading volumes spiked. Positive Sentiment: Leerink Partnrs raised its FY2027 loss estimate to ($2.35) per share from ($3.10), signaling a smaller-than-expected decline in earnings. Positive Sentiment: Stoke Therapeutics received a consensus “Buy” rating from ten analysts, reflecting strong confidence among Wall Street firms. Consensus Buy Rating Neutral Sentiment: Short interest remained at zero shares with a days-to-cover ratio of 0.0, indicating minimal bearish positioning. Neutral Sentiment: The stock experienced an 11.7% surge on higher-than-average volume, though recent downward revisions to estimates may curb further gains. Surge Analysis Neutral Sentiment: Trading volume spiked to unusual levels, but there was no specific catalyst identified. Volume Spike Negative Sentiment: Leerink Partnrs cut its FY2028 EPS estimate sharply to ($2.80) from ($1.40), deepening the projected loss outlook. Negative Sentiment: Leerink Partnrs lowered its FY2029 forecast to a $0.40 loss per share from prior expectations of $0.30 in earnings. Negative Sentiment: Weiss Ratings reaffirmed a “Sell (D+)” rating, underscoring persistent skepticism among some analysts. Weiss Ratings Sell Rating Negative Sentiment: Stoke’s general counsel sold 10,000 shares at an average price of $25.07, reducing insider holdings and potentially signaling less confidence at the executive level. Insider Sale Overall, mixed analyst revisions and a reiterated sell rating have weighed on STOK, partially offset by a consensus buy stance and an improved FY2027 outlook. Investors should watch upcoming clinical milestones and guidance for clearer direction.Posted 4h agoAI Generated. May Contain Errors. STOK Latest News All Sources Trusted Sources MarketBeat Barchart Benzinga Bloomberg GlobeNewswire GuruFocus MarketWatch Motley Fool NASDAQ PR Newswire Reuters Seeking Alpha TalkMarkets The Street TipRanks The Wall Street Journal Wall Street Zen Yahoo Finance Source Sentiment refers to the positivity or negativity of each headline according to our language processing algorithm. Sentiment All Sentiments Very Positive Positive Neutral Negative Very Negative Most Recent October 2025 September 2025 August 2025 July 2025 June 2025 May 2025 April 2025 March 2025 February 2025 January 2025 December 2024 November 2024 October 2024 September 2024 August 2024 July 2024 June 2024 May 2024 April 2024 March 2024 February 2024 January 2024 December 2023 November 2023 October 2023 September 2023 August 2023 July 2023 June 2023 May 2023 April 2023 March 2023 February 2023 January 2023 December 2022 November 2022 Time Period Biogen and Stoke Therapeutics Present New Data at the 54th Child Neurology Society (CNS) Annual Meeting that Support the Potential of Zorevunersen as a Disease-Modifying ...4 hours ago | markets.businessinsider.comStoke, Biogen presents new data from OLE studies of zorevunersen4 hours ago | msn.comStoke Therapeutics and Biogen Present New Data at the 54th Child Neurology Society (CNS) Annual Meeting that Support the Potential of Zorevunersen as a Disease-Modifying ...4 hours ago | finance.yahoo.comStoke Therapeutics (NASDAQ:STOK) Given "Sell (D+)" Rating at Weiss RatingsOctober 9 at 2:27 AM | marketbeat.comStoke Therapeutics (NASDAQ:STOK) Sees Unusually-High Trading Volume - Here's WhyOctober 8 at 2:10 PM | marketbeat.comStoke Therapeutics (NASDAQ:STOK) General Counsel Sells $250,700.00 in StockOctober 8 at 5:21 AM | insidertrades.comStoke Therapeutics, Inc. (NASDAQ:STOK) Receives Consensus Rating of "Buy" from AnalystsOctober 8 at 2:55 AM | americanbankingnews.comStoke Therapeutics, Inc. (NASDAQ:STOK) Receives Consensus Recommendation of "Buy" from AnalystsOctober 8 at 2:54 AM | marketbeat.comStoke Therapeutics (NASDAQ:STOK) General Counsel Jonathan Allan Sells 10,000 SharesOctober 7 at 6:48 PM | marketbeat.comStoke Therapeutics (NASDAQ:STOK) Director Sells 42,461 SharesOctober 7 at 6:47 PM | marketbeat.comStoke Therapeutics stock rises after appointing Ian Smith as CEOOctober 6 at 11:50 AM | investing.comStoke Therapeutics Appoints Smith as Permanent CEOOctober 6 at 11:50 AM | marketwatch.comStoke Therapeutics (NASDAQ:STOK) Sets New 12-Month High - Still a Buy?October 6 at 11:29 AM | marketbeat.comStoke Therapeutics Appoints Ian F. Smith as Chief Executive OfficerOctober 6 at 7:30 AM | businesswire.comStoke Therapeutics (NASDAQ:STOK) Sets New 52-Week High - Here's WhySeptember 29, 2025 | marketbeat.comStoke Therapeutics (NASDAQ:STOK) Trading Up 4.9% - Still a Buy?September 26, 2025 | marketbeat.comAssenagon Asset Management S.A. Sells 421,630 Shares of Stoke Therapeutics, Inc. $STOKSeptember 24, 2025 | marketbeat.comStoke Therapeutics (NASDAQ:STOK) Trading Down 5.1% - Time to Sell?September 20, 2025 | marketbeat.comStoke Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(C)(4)September 16, 2025 | businesswire.comStoke Therapeutics, Inc. (NASDAQ:STOK) Receives Consensus Recommendation of "Buy" from BrokeragesSeptember 15, 2025 | marketbeat.comSiren L.L.C. Buys 247,347 Shares of Stoke Therapeutics, Inc. $STOKSeptember 13, 2025 | marketbeat.comJacobs Levy Equity Management Inc. Purchases New Stake in Stoke Therapeutics, Inc. $STOKSeptember 13, 2025 | marketbeat.comStoke Therapeutics (NASDAQ:STOK) Trading Down 5.4% - Time to Sell?September 11, 2025 | marketbeat.comStoke Therapeutics (STOK) Unveils Promising Data For Dravet Syndrome DrugSeptember 11, 2025 | finance.yahoo.comStoke Therapeutics (NASDAQ:STOK) Hits New 1-Year High - Still a Buy?September 10, 2025 | marketbeat.comStoke Therapeutics, Inc. $STOK Shares Sold by Trexquant Investment LPSeptember 10, 2025 | marketbeat.comInvesco Ltd. Raises Stock Holdings in Stoke Therapeutics, Inc. $STOKSeptember 10, 2025 | marketbeat.comStoke Therapeutics, Inc. $STOK Shares Bought by Granahan Investment Management LLCSeptember 7, 2025 | marketbeat.comStoke Therapeutics, Inc. $STOK is Checkpoint Capital L.P.'s 7th Largest PositionSeptember 6, 2025 | marketbeat.com16,119 Shares in Stoke Therapeutics, Inc. $STOK Acquired by Russell Investments Group Ltd.September 6, 2025 | marketbeat.comInsider Selling: Stoke Therapeutics (NASDAQ:STOK) General Counsel Sells 850 Shares of StockSeptember 5, 2025 | marketbeat.comEdward Md Kaye Sells 1,029 Shares of Stoke Therapeutics (NASDAQ:STOK) StockSeptember 5, 2025 | marketbeat.comStoke Therapeutics (NASDAQ:STOK) Insider Barry Ticho Sells 5,501 SharesSeptember 5, 2025 | marketbeat.comStoke Therapeutics (NASDAQ:STOK) General Counsel Jonathan Allan Sells 6,345 SharesSeptember 5, 2025 | marketbeat.comInsider Selling: Stoke Therapeutics (NASDAQ:STOK) Director Sells $299,280.40 in StockSeptember 5, 2025 | marketbeat.comStoke Therapeutics (NASDAQ:STOK) General Counsel Sells $300,529.08 in StockSeptember 5, 2025 | marketbeat.comEdward Md Kaye Sells 45,996 Shares of Stoke Therapeutics (NASDAQ:STOK) StockSeptember 5, 2025 | marketbeat.comADAR1 Capital Management LLC Buys Shares of 30,085 Stoke Therapeutics, Inc. $STOKSeptember 5, 2025 | marketbeat.comStoke Therapeutics (NASDAQ:STOK) Hits New 1-Year High - Here's WhySeptember 4, 2025 | marketbeat.comRedmile Group LLC Sells 107,648 Shares of Stoke Therapeutics, Inc. $STOKSeptember 4, 2025 | marketbeat.comJonathan Allan Sells 850 Shares of Stoke Therapeutics (NASDAQ:STOK) StockSeptember 4, 2025 | insidertrades.comNuveen LLC Invests $719,000 in Stoke Therapeutics, Inc. $STOKSeptember 4, 2025 | marketbeat.comStoke Therapeutics and Biogen Present Data at the 36th International Epilepsy Congress that Support the Potential for Zorevunersen to be the First Disease-Modifying Medicine ...September 2, 2025 | uk.finance.yahoo.comStoke Therapeutics, Inc. $STOK Shares Sold by Deutsche Bank AGSeptember 2, 2025 | marketbeat.comCharles Schwab Investment Management Inc. Cuts Stake in Stoke Therapeutics, Inc. $STOKSeptember 2, 2025 | marketbeat.comDAFNA Capital Management LLC Raises Holdings in Stoke Therapeutics, Inc. $STOKSeptember 1, 2025 | marketbeat.comStoke Therapeutics, Inc. $STOK Shares Purchased by Vanguard Group Inc.September 1, 2025 | marketbeat.comStoke Therapeutics, Inc. $STOK Shares Purchased by Siren L.L.C.August 31, 2025 | marketbeat.comStoke Therapeutics to Present at Upcoming Investor Conferences in September 2025August 28, 2025 | businesswire.comStoke Therapeutics: Vulnerable To Profit TakingAugust 27, 2025 | seekingalpha.com Get Stoke Therapeutics News Delivered to You Automatically Sign up to receive the latest news and ratings for STOK and its competitors with MarketBeat's FREE daily newsletter. 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Our company news sentiment scores track the average news sentiment of articles about each company over the most recent 7 days in order to identify companies that are receiving positive press. STOK News Sentiment▼0.420.77▲Average Medical News Sentiment STOK News Coverage Learn about the media coverage comparison. We track news headlines from hundreds of news outlets and tag them by company. This chart compares the number of articles about this company in the last seven days compared with the average number of articles about this company on a typical week. STOK Articles This Week▼186▲STOK Articles Average Week Get the Latest News and Ratings for STOK and Related Stocks Enter your email address to receive the latest news and analysts' ratings for Stoke Therapeutics and its competitors. 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