VistaGen Therapeutics (VTGN) Stock Price, News & Analysis

Company Overview

VistaGen Therapeutics, Inc. (NASDAQ:VTGN) is a clinical-stage biopharmaceutical company dedicated to the discovery and development of next-generation medicines for central nervous system disorders. Incorporated in Delaware in 1998 and headquartered in South San Francisco, California, VistaGen applies advanced human pluripotent stem cell technologies to accelerate drug candidate validation and optimization. The company’s core focus is on addressing unmet medical needs in major depressive disorder, neuropathic pain and dermatological conditions.

The company’s lead candidate, AV-101, is an oral prodrug designed to modulate glutamatergic neurotransmission via the N-methyl-D-aspartate (NMDA) receptor pathway, with clinical programs targeting major depressive disorder and neuropathic pain. VistaGen also develops PH-10, a topical neuroactive small molecule in clinical development for psoriasis and atopic dermatitis. To broaden its development reach, VistaGen has entered strategic partnerships, including a licensing agreement with Yuhan Corporation for AV-101 in South Korea, and continues to advance its clinical and regulatory strategy primarily in North America and Asia.

VistaGen’s proprietary Human Clinical Drug Rescue and ReRationalization platform employs patient-derived pluripotent stem cell–derived neural and cardiac cells to predict clinical efficacy and safety, reduce late-stage development risk and complement traditional preclinical models. This platform supports both in-house pipeline programs and collaborative research initiatives. Leading the company is President and Chief Executive Officer Shawn K. Singh, who has overseen VistaGen’s research and corporate development efforts since joining in 2014 and remains committed to translating innovative science into new therapeutic options for underserved patient populations.

Key Stats

• Today's Range: $3.37 to $3.53
• 50-Day Range: $2.21 to $3.69
• 52-Week Range: $1.90 to $3.88
• Volume: 318,906 shs
• Average Volume: 613,891 shs
• Market Capitalization: $104.01 million
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: N/A
• Consensus Rating: Buy

VistaGen Therapeutics Stock Analysis - MarketRank™

VistaGen Therapeutics scored higher than 20% of companies evaluated by MarketBeat, and ranked 883rd out of 958 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: N/A
• Analyst Rating: N/A

Consensus Rating

There is not enough analysis data for VistaGen Therapeutics.

Earnings and Valuation

• Score: 0.6 / 5
• Proj. Earnings Growth: Growing

Earnings Growth

Earnings for VistaGen Therapeutics are expected to grow in the coming year, from ($1.77) to ($1.74) per share.

Price to Earnings Ratio vs. the Market

The P/E ratio of VistaGen Therapeutics is -1.90, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of VistaGen Therapeutics is -1.90, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Book Value per Share Ratio

VistaGen Therapeutics has a P/B Ratio of 1.39. P/B Ratios below 3 indicates that a company is reasonably valued with respect to its assets and liabilities.

Short Interest

• Score: 3.0 / 5
• Short Interest Level: Healthy

Percentage of Shares Shorted

3.41% of the float of VistaGen Therapeutics has been sold short.

Short Interest Ratio / Days to Cover

VistaGen Therapeutics has a short interest ratio ("days to cover") of 2.2, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in VistaGen Therapeutics has recently increased by 55.71%, indicating that investor sentiment is decreasing significantly.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

VistaGen Therapeutics does not currently pay a dividend.

Dividend Growth

VistaGen Therapeutics does not have a long track record of dividend growth.

Sustainability and ESG

• Score: N/A
• Environmental Score: N/A

Percentage of Shares Shorted

3.41% of the float of VistaGen Therapeutics has been sold short.

Short Interest Ratio / Days to Cover

VistaGen Therapeutics has a short interest ratio ("days to cover") of 2.2, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in VistaGen Therapeutics has recently increased by 55.71%, indicating that investor sentiment is decreasing significantly.

News and Social Media

• Score: 2.9 / 5
• News Sentiment: 0.30

News Sentiment

VistaGen Therapeutics has a news sentiment score of 0.30. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.93 average news sentiment score of Medical companies.

News Coverage This Week

MarketBeat has tracked 3 news articles for VistaGen Therapeutics this week, compared to 1 article on an average week.

Search Interest

9 people have searched for VTGN on MarketBeat in the last 30 days. This is an increase of 350% compared to the previous 30 days.

MarketBeat Follows

3 people have added VistaGen Therapeutics to their MarketBeat watchlist in the last 30 days. This is an increase of 200% compared to the previous 30 days.

Company Ownership

• Score: 1.7 / 5
• Insider Trading: N/A

Insider Buying vs. Insider Selling

In the past three months, VistaGen Therapeutics insiders have not sold or bought any company stock.

Percentage Held by Insiders

Only 2.85% of the stock of VistaGen Therapeutics is held by insiders.

Percentage Held by Institutions

78.39% of the stock of VistaGen Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.

VTGN Stock Analysis - Frequently Asked Questions

How have VTGN shares performed this year?

VistaGen Therapeutics' stock was trading at $2.95 at the beginning of the year. Since then, VTGN stock has increased by 14.9% and is now trading at $3.39.

How were VistaGen Therapeutics' earnings last quarter?

VistaGen Therapeutics, Inc. (NASDAQ:VTGN) posted its earnings results on Thursday, August, 7th. The company reported ($0.47) EPS for the quarter, hitting the consensus estimate of ($0.47). The company earned $0.24 million during the quarter, compared to analyst estimates of $0.22 million. VistaGen Therapeutics had a negative trailing twelve-month return on equity of 74.06% and a negative net margin of 6,777.08%.
Read the conference call transcript.

When did VistaGen Therapeutics' stock split?

Shares of VistaGen Therapeutics reverse split before market open on Wednesday, June 7th 2023.The 1-30 reverse split was announced on Wednesday, June 7th 2023. The number of shares owned by shareholders was adjusted after the closing bell on Wednesday, June 7th 2023. An investor that had 100 shares of stock prior to the reverse split would have 3 shares after the split.

Who are VistaGen Therapeutics' major shareholders?

VistaGen Therapeutics' top institutional shareholders include Stempoint Capital LP (7.87%), AdvisorShares Investments LLC (0.68%), Jane Street Group LLC (0.31%) and Persistent Asset Partners Ltd (0.28%).
View institutional ownership trends.

How do I buy shares of VistaGen Therapeutics?

Shares of VTGN stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of VistaGen Therapeutics own?

Based on aggregate information from My MarketBeat watchlists, some other companies that VistaGen Therapeutics investors own include NVIDIA (NVDA), Meta Platforms (META), Broadcom (AVGO), CrowdStrike (CRWD), Adobe (ADBE), Advanced Micro Devices (AMD) and Arista Networks (ANET).

Company Calendar

• Last Earnings: 8/07/2025
• Today: 9/13/2025
• Next Earnings (Estimated): 11/06/2025
• Fiscal Year End: 3/31/2026

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Medical
• Industry: MED - BIOMED/GENE
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NASDAQ:VTGN
• CIK: 1411685
• Web: www.vistagen.com
• Phone: (650) 577-3600
• Fax: 888-482-2602
• Employees: 40
• Year Founded: 1998

Profitability

• EPS (Trailing Twelve Months): ($1.78)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: -$51.42 million
• Net Margins: -6,777.08%
• Pretax Margin: -8,633.59%
• Return on Equity: -74.06%
• Return on Assets: -64.10%

Debt

• Debt-to-Equity Ratio: N/A
• Current Ratio: 5.98
• Quick Ratio: 5.98

Sales & Book Value

• Annual Sales: $490 thousand
• Price / Sales: 212.26
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: $2.44 per share
• Price / Book: 1.39

Miscellaneous

• Outstanding Shares: 30,680,000
• Free Float: 29,806,000
• Market Cap: $104.01 million
• Optionable: Optionable
• Beta: 0.55